| Entry |
|
|---|
| Name |
Solengepras (USAN) |
|---|
| Formula |
C24H29F2N5O3
|
|---|
| Exact mass |
473.2238
|
|---|
| Mol weight |
473.52
|
|---|
| Structure |
|
|---|
| Efficacy |
Antiparkinsonian, GPR6 inverse agonist |
|---|
| Comment |
Treatment of Parkinson's disease
|
|---|
| Target |
|
|---|
| Brite |
Target-based classification of drugs [BR:br08310]
G Protein-coupled receptors
Rhodopsin family
Orphan GPCR
GPR6
D12980 Solengepras (USAN)
|
|---|
| Other DBs |
|
|---|
| LinkDB |
|
|---|
| KCF data |
ATOM 34
1 C8y C 15.3300 -16.5200
2 C8y C 15.3300 -17.9200
3 N5x N 16.5424 -18.6200
4 C8y C 17.7549 -17.9200
5 C8y C 17.7549 -16.5200
6 N5x N 16.5424 -15.8200
7 C1x C 18.9673 -18.6200
8 N1y N 20.1797 -17.9200
9 C1x C 20.1797 -16.5200
10 C1x C 18.9673 -15.8200
11 C5a C 21.3773 -18.6115
12 C1a C 22.5656 -17.9255
13 O5a O 21.3774 -20.0197
14 N1b N 14.1176 -18.6200
15 N1y N 14.1176 -15.8200
16 C1x C 14.1176 -14.4202
17 C1x C 12.9051 -13.7202
18 C1y C 11.6927 -14.4202
19 C1x C 11.6927 -15.8200
20 C1x C 12.9051 -16.5200
21 O2a O 10.4782 -13.7190
22 C8y C 9.2818 -14.4099
23 C8y C 8.0949 -13.7247
24 C8x C 6.8825 -14.4247
25 C8y C 6.8825 -15.8247
26 C8x C 8.0694 -16.5099
27 C8x C 9.2818 -15.8099
28 X F 8.0948 -12.3202
29 X F 5.6554 -16.5334
30 C1y C 14.1175 -20.0198
31 C1x C 12.9996 -20.8321
32 O2x O 13.4267 -22.1463
33 C1x C 14.8086 -22.1462
34 C1x C 15.2355 -20.8320
BOND 38
1 1 2 2
2 2 3 1
3 3 4 2
4 4 5 1
5 5 6 2
6 1 6 1
7 4 7 1
8 7 8 1
9 8 9 1
10 9 10 1
11 5 10 1
12 8 11 1
13 11 12 1
14 11 13 2
15 2 14 1
16 1 15 1
17 15 16 1
18 16 17 1
19 17 18 1
20 18 19 1
21 19 20 1
22 15 20 1
23 18 21 1
24 21 22 1
25 22 23 2
26 23 24 1
27 24 25 2
28 25 26 1
29 26 27 2
30 22 27 1
31 23 28 1
32 25 29 1
33 30 14 1 #Down
34 30 31 1
35 31 32 1
36 32 33 1
37 33 34 1
38 30 34 1
|
|---|
