Cibotercept (USAN/INN)

C1711H2625N467O532S19

38833.7402

38858.24

GRGEAETREC LYYNANWELE RTNQSGVERC EGEKDKRLHC YASWRNSSGS LEIVKKGCWL
DDFNCYDRDT CVATKENPQV YFCCCEGNMC NERFTHLPEA GGPEVTYEPP PTAPTGGGDK
THTCPPCPAP ELLGGPSVFL FPPKPKDTLM ISRTPEVTCV VVDVSHEDPE VKFNWYVDGV
EVHNAKTKPR EEQYNSTYRV VSVLTVLHQD WLNGKEYKCK VSNKALPAPI EKTISKAKGQ
PREPQVYTLP PSRDELTKNQ VSLTCLVKGF YPSDIAVEWE SNGQPENNYK TTPPVLDSDG
SFFLYSKLTV DKSRWQQGNV FSCSVMHEAL HNHYTQKSLS LSPG
(Disulfide bridge: 10-40, 30-58, 65-84, 71-83, 85-90, 124-124', 127-127', 159-219, 265-323, 10'-40', "30'-58', 65'-84', 71'-83', 85'-90', 159'-219', 265'-323')

Ligand trap

Treatment of pulmonary arterial hypertension and bone diseases, including osteoporosis and osteogenesis imperfecta

ACVR2B [HSA:93] [KO:K13596]