| Entry |
|
|---|
| Name |
Imdatifan (USAN/INN) |
|---|
| Formula |
C18H9F6NO2
|
|---|
| Exact mass |
385.0537
|
|---|
| Mol weight |
385.26
|
|---|
| Structure |
|
|---|
| Class |
Antineoplastic
DG03327 Hypoxia-inducible factor-2 alpha inhibitor
|
|---|
| Efficacy |
Antineoplastic, Hypoxia-inducible factor-2 alpha inhibitor |
|---|
| Comment |
Treatment of clear renal cell carcinoma
|
|---|
| Target |
|
|---|
| Pathway |
|
|---|
| Brite |
Drug groups [BR:br08330]
Antineoplastic
DG03327 Hypoxia-inducible factor-2 alpha inhibitor
D13003 Imdatifan
Target-based classification of drugs [BR:br08310]
Not elsewhere classified
Genetic information processing
Transcription factor
HIF2A (EPAS1)
D13003 Imdatifan (USAN/INN)
|
|---|
| Other DBs |
|
|---|
| LinkDB |
|
|---|
| KCF data |
ATOM 27
1 C8x C 18.7600 -13.8600
2 C8x C 18.7600 -15.2600
3 C8y C 19.9500 -15.9600
4 C8y C 21.2100 -15.2600
5 C8y C 21.2100 -13.8600
6 C8y C 19.9500 -13.1600
7 C1y C 22.5400 -15.6800
8 C1x C 23.3800 -14.5600
9 C1z C 22.4000 -13.3700
10 O2a O 19.9500 -17.3600
11 C8y C 18.7600 -18.0600
12 C8x C 17.5700 -17.3600
13 C8y C 16.3100 -18.0600
14 C8x C 16.3100 -19.4600
15 C8y C 17.5700 -20.1600
16 C8x C 18.7600 -19.4600
17 X F 17.5700 -21.5600
18 C3b C 15.1200 -17.3600
19 N3a N 13.8600 -16.6600
20 C1z C 21.9800 -11.8300
21 C1z C 20.5100 -11.8300
22 X F 22.9600 -17.0100
23 O1a O 23.7300 -13.0200
24 X F 20.7200 -10.4300
25 X F 23.4500 -11.8300
26 X F 19.1100 -11.8300
27 X F 21.7700 -10.4300
BOND 30
1 1 2 2
2 2 3 1
3 3 4 2
4 4 5 1
5 5 6 2
6 1 6 1
7 4 7 1
8 7 8 1
9 8 9 1
10 5 9 1
11 3 10 1
12 10 11 1
13 11 12 2
14 12 13 1
15 13 14 2
16 14 15 1
17 15 16 2
18 11 16 1
19 15 17 1
20 13 18 1
21 18 19 3
22 9 20 1
23 6 21 1
24 21 20 1
25 7 22 1 #Down
26 9 23 1 #Down
27 21 24 1
28 20 25 1
29 21 26 1
30 20 27 1
|
|---|
