KEGG   DRUG: Olezarsen sodium
Entry
D13023                      Drug                                   
Name
Olezarsen sodium (USAN);
Tryngolza (TN)
Product
TRYNGOLZA (Ionis Pharmaceuticals)
Formula
C296H419N71O154P20S19.20Na
Exact mass
9118.4538
Mol weight
9124.43
Remark
Product: D13023<US>
Efficacy
Lipid-lowering agent, Translation inhibitor
  Disease
Familial chylomicronemia syndrome [DS:H00154]
  Type
Antisense oligonucleotide
Comment
Treatment of hypertriglyceridemia in patients with cardiovascular disease
Target
APOC3 [HSA:345] [KO:K08759] (mRNA)
  Pathway
hsa03320  PPAR signaling pathway
hsa04979  Cholesterol metabolism
Brite
Target-based classification of drugs [BR:br08310]
 Not elsewhere classified
  Organismal systems
   Digestive system
    APOC3
     D13023  Olezarsen sodium (USAN) <US>
New drug approvals in the USA [br08319.html]
 New molecular entities and new therapeutic biological products
  D13023
New drug approvals in the USA, Europe and Japan [br08328.html]
 Approval dates by FDA, EMA and PMDA
  D13023
Other DBs
CAS: 2298451-31-5
PubChem: 505120112
LinkDB

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