| Entry |
|
|---|
| Name |
Bexicaserin (USAN/INN) |
|---|
| Formula |
C15H19F2N3O
|
|---|
| Exact mass |
295.1496
|
|---|
| Mol weight |
295.33
|
|---|
| Structure |
|
|---|
| Remark |
|
|---|
| Efficacy |
Antiepileptic, Serotonin receptor agonist |
|---|
| Comment |
Treatment of seizures associated with developmental and epileptic encephalopathies
|
|---|
| Target |
|
|---|
| Pathway |
| hsa04080 | Neuroactive ligand-receptor interaction |
|
|---|
| Brite |
Target-based classification of drugs [BR:br08310]
G Protein-coupled receptors
Rhodopsin family
Serotonin
HTR2C
D13035 Bexicaserin (USAN/INN)
|
|---|
| Other DBs |
|
|---|
| LinkDB |
|
|---|
| KCF data |
ATOM 21
1 C1x C 18.4800 -19.3900
2 C1x C 17.6400 -18.2700
3 N1y N 17.9900 -16.8700
4 C8y C 19.2500 -16.3100
5 N1x N 19.9500 -19.3900
6 C8y C 20.5100 -16.9400
7 C1x C 20.8600 -18.2700
8 C8y C 19.2500 -14.9100
9 C8y C 20.5100 -14.2100
10 C8x C 21.7000 -14.9100
11 C8x C 21.7000 -16.3100
12 C1x C 17.1500 -15.7500
13 C1y C 17.9900 -14.6300
14 C1a C 17.5043 -13.3170
15 C5a C 20.5272 -12.8101
16 O5a O 19.3108 -12.0876
17 N1b N 21.7351 -12.1324
18 C1b C 22.9542 -12.8568
19 C1c C 24.1698 -12.1754
20 X F 25.3605 -12.8833
21 X F 24.1175 -10.7805
BOND 23
1 3 4 1
2 1 5 1
3 4 6 1
4 2 3 1
5 5 7 1
6 1 2 1
7 6 7 1
8 4 8 2
9 8 9 1
10 9 10 2
11 10 11 1
12 11 6 2
13 3 12 1
14 12 13 1
15 8 13 1
16 13 14 1 #Down
17 9 15 1
18 15 16 2
19 15 17 1
20 17 18 1
21 18 19 1
22 19 20 1
23 19 21 1
|
|---|
