KEGG   DRUG: Aceclidine hydrochloride
Entry
D13152                      Drug                                   
Name
Aceclidine hydrochloride;
Vizz (TN)
Product
VIZZ (LENZ Therapeutics)
Formula
C9H15NO2. HCl
Exact mass
205.0870
Mol weight
205.68
Structure
Class
Neuropsychiatric agent
 DG01490  Muscarinic cholinergic receptor agonist
Remark
ATC code: S01EB08
Chemical structure group: DG03358
Product (DG03358): D13152<US>
Efficacy
Miotic, Muscarinic acetylcholine receptor agonist
Comment
Treatment of presbyopia
Target
CHRM1 [HSA:1128] [KO:K04129]
  Pathway
hsa04080  Neuroactive ligand-receptor interaction
hsa04082  Neuroactive ligand signaling
hsa04725  Cholinergic synapse
Interaction
Brite
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
 S SENSORY ORGANS
  S01 OPHTHALMOLOGICALS
   S01E ANTIGLAUCOMA PREPARATIONS AND MIOTICS
    S01EB Parasympathomimetics
     S01EB08 Aceclidine
      D13152  Aceclidine hydrochloride <US>
USP drug classification [BR:br08302]
 Ophthalmic Agents
  Ophthalmic Agents, Other
   Aceclidine
    D13152  Aceclidine hydrochloride
Drug groups [BR:br08330]
 Neuropsychiatric agent
  DG01490  Muscarinic cholinergic receptor agonist
   DG03358  Aceclidine
    D13152  Aceclidine hydrochloride
Target-based classification of drugs [BR:br08310]
 G Protein-coupled receptors
  Rhodopsin family
   Acetylcholine (muscarinic)
    CHRM1
     D13152  Aceclidine hydrochloride <US>
New drug approvals in the USA [br08319.html]
 New molecular entities and new therapeutic biological products
  D13152
New drug approvals in the USA, Europe and Japan [br08328.html]
 Approval dates by FDA, EMA and PMDA
  D13152
Drug groups [BR:br08330]
 Neuropsychiatric agent
  DG01490  Muscarinic cholinergic receptor agonist
   DG03358  Aceclidine
Other DBs
CAS: 6109-70-2
PubChem: 518520872
LinkDB
KCF data

ATOM        13
            1   O7a O    19.2636  -14.5361
            2   C7a C    20.5336  -15.2417
            3   C1a C    21.7331  -14.5361
            4   O6a O    20.5336  -16.5823
            5   C1y C    18.0641  -15.2417
            6   C1x C    18.0641  -16.6529
            7   C1y C    16.7940  -14.5361
            8   C1x C    15.5240  -15.2417
            9   C1x C    15.5240  -16.6529
            10  C1x C    16.2295  -15.8062
            11  C1x C    17.3585  -16.3001
            12  N1y N    16.7235  -17.4290
            13  X   Cl   23.2400  -17.5700
BOND        13
            1     1   2 1
            2     2   3 1
            3     2   4 2
            4     1   5 1
            5     5   6 1
            6     5   7 1
            7     7   8 1
            8     8   9 1
            9     7  10 1
            10   10  11 1
            11   12   9 1
            12    6  12 1
            13   12  11 1

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