| Entry |
|
|---|
| Name |
Naperiglipron (USAN) |
|---|
| Formula |
C33H26F2N4O4
|
|---|
| Exact mass |
580.1922
|
|---|
| Mol weight |
580.58
|
|---|
| Structure |
|
|---|
| Class |
Antidiabetic agent
DG02044 Hypoglycemic agent
DG01493 GLP-1 receptor agonist
|
|---|
| Remark |
|
|---|
| Efficacy |
Antidiabetic, Antiobesity, Glucagon-like peptide 1 (GLP-1) receptor agonist |
|---|
| Comment |
Treatment of diabetes and chronic weight management
|
|---|
| Target |
|
|---|
| Pathway |
| hsa04080 | Neuroactive ligand-receptor interaction |
|
|---|
| Interaction |
|
|---|
| Brite |
Drug groups [BR:br08330]
Antidiabetic agent
DG02044 Hypoglycemic agent
DG01493 GLP-1 receptor agonist
DG03364 Naperiglipron
D13181 Naperiglipron
Target-based classification of drugs [BR:br08310]
G Protein-coupled receptors
Secretin receptor family
Glucagon
GLP1R
D13181 Naperiglipron (USAN)
Drug groups [BR:br08330]
Antidiabetic agent
DG02044 Hypoglycemic agent
DG01493 GLP-1 receptor agonist
DG03364 Naperiglipron
|
|---|
| Other DBs |
|
|---|
| LinkDB |
|
|---|
| KCF data |
ATOM 43
1 C8y C 23.4500 -15.6100
2 C1b C 24.7100 -14.9100
3 C8y C 25.9000 -15.6100
4 N4y N 25.8300 -17.0100
5 C8y C 27.1600 -17.5000
6 C8y C 28.0700 -16.3800
7 N5x N 27.2300 -15.1900
8 C1b C 24.7100 -17.7800
9 C1y C 24.7100 -19.1800
10 O2x O 23.7300 -20.1600
11 C1x C 24.7100 -21.1400
12 C1x C 25.6900 -20.1600
13 C8x C 27.7200 -18.7600
14 C8y C 29.0500 -18.9700
15 C8x C 29.9600 -17.8500
16 C8x C 29.4000 -16.5900
17 C6a C 29.6100 -20.2300
18 O6a O 30.9400 -20.4400
19 O6a O 28.7000 -21.3500
20 C8x C 23.4500 -17.0100
21 C8y C 22.1900 -17.7100
22 C8y C 21.0000 -16.9400
23 C8x C 21.0000 -15.5400
24 C8y C 22.2600 -14.9100
25 C8y C 19.8100 -17.6400
26 N5x N 19.8100 -19.0400
27 C8y C 18.5500 -19.7400
28 C8x C 17.3600 -18.9700
29 C8x C 17.3600 -17.5700
30 C8x C 18.6200 -16.9400
31 X F 22.2600 -13.5100
32 C1a C 22.1900 -19.1100
33 O2a O 18.5500 -21.1400
34 C1b C 17.3600 -21.8400
35 C8y C 16.1000 -21.2100
36 C8y C 14.9100 -21.9100
37 C8x C 13.6500 -21.2800
38 C8y C 13.6500 -19.8800
39 C8x C 14.8400 -19.1100
40 C8x C 16.1000 -19.8100
41 X F 14.9100 -23.3100
42 C3b C 12.4600 -19.1800
43 N3a N 11.2000 -18.4800
BOND 48
1 1 2 1
2 2 3 1
3 3 4 1
4 4 5 1
5 5 6 2
6 6 7 1
7 3 7 2
8 4 8 1
9 9 8 1 #Down
10 9 10 1
11 10 11 1
12 11 12 1
13 9 12 1
14 5 13 1
15 13 14 2
16 14 15 1
17 15 16 2
18 6 16 1
19 14 17 1
20 17 18 1
21 17 19 2
22 1 20 2
23 20 21 1
24 21 22 2
25 22 23 1
26 23 24 2
27 1 24 1
28 22 25 1
29 25 26 2
30 26 27 1
31 27 28 2
32 28 29 1
33 29 30 2
34 25 30 1
35 24 31 1
36 21 32 1
37 27 33 1
38 33 34 1
39 34 35 1
40 35 36 2
41 36 37 1
42 37 38 2
43 38 39 1
44 39 40 2
45 35 40 1
46 36 41 1
47 38 42 1
48 42 43 3
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|---|
