| Entry |
|
|---|
| Name |
Naperiglipron erbumine (USAN) |
|---|
| Formula |
C33H26F2N4O4. C4H11N
|
|---|
| Exact mass |
653.2814
|
|---|
| Mol weight |
653.72
|
|---|
| Structure |
|
|---|
| Class |
Antidiabetic agent
DG02044 Hypoglycemic agent
DG01493 GLP-1 receptor agonist
|
|---|
| Remark |
|
|---|
| Efficacy |
Antidiabetic, Antiobesity, Glucagon-like peptide 1 (GLP-1) receptor agonist |
|---|
| Comment |
Treatment of diabetes and chronic weight management
|
|---|
| Target |
|
|---|
| Pathway |
| hsa04080 | Neuroactive ligand-receptor interaction |
|
|---|
| Interaction |
|
|---|
| Brite |
Drug groups [BR:br08330]
Antidiabetic agent
DG02044 Hypoglycemic agent
DG01493 GLP-1 receptor agonist
DG03364 Naperiglipron
D13182 Naperiglipron erbumine
Target-based classification of drugs [BR:br08310]
G Protein-coupled receptors
Secretin receptor family
Glucagon
GLP1R
D13182 Naperiglipron erbumine (USAN)
Drug groups [BR:br08330]
Antidiabetic agent
DG02044 Hypoglycemic agent
DG01493 GLP-1 receptor agonist
DG03364 Naperiglipron
|
|---|
| Other DBs |
|
|---|
| LinkDB |
|
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| KCF data |
ATOM 48
1 C8y C 20.9885 -13.1528
2 C1b C 22.2478 -12.4532
3 C8y C 23.4371 -13.1528
4 N4y N 23.3672 -14.5520
5 C8y C 24.6964 -15.0417
6 C8y C 25.6059 -13.9224
7 N5x N 24.7664 -12.7330
8 C1b C 22.2478 -15.3216
9 C1y C 22.2478 -16.7208
10 O2x O 21.2683 -17.7003
11 C1x C 22.2478 -18.6797
12 C1x C 23.2272 -17.7003
13 C8x C 25.2561 -16.3011
14 C8y C 26.5854 -16.5109
15 C8x C 27.4949 -15.3916
16 C8x C 26.9352 -14.1322
17 C6a C 27.1451 -17.7702
18 O6a O 28.4744 -17.9801
19 O6a O 26.2356 -18.8896
20 C8x C 20.9885 -14.5520
21 C8y C 19.7292 -15.2516
22 C8y C 18.5398 -14.4821
23 C8x C 18.5398 -13.0828
24 C8y C 19.7991 -12.4532
25 C8y C 17.3505 -15.1817
26 N5x N 17.3505 -16.5809
27 C8y C 16.0912 -17.2805
28 C8x C 14.9018 -16.5109
29 C8x C 14.9018 -15.1117
30 C8x C 16.1611 -14.4821
31 X F 19.7991 -11.0539
32 C1a C 19.7292 -16.6509
33 O2a O 16.0912 -18.6797
34 C1b C 14.9018 -19.3794
35 C8y C 13.6425 -18.7497
36 C8y C 12.4532 -19.4493
37 C8x C 11.1939 -18.8197
38 C8y C 11.1939 -17.4204
39 C8x C 12.3832 -16.6509
40 C8x C 13.6425 -17.3505
41 X F 12.4532 -20.8486
42 C3b C 10.0045 -16.7208
43 N3a N 8.7452 -16.0212
44 C1d C 32.2000 -14.9100
45 N1a N 32.2000 -13.5100
46 C1a C 30.8000 -14.9100
47 C1a C 33.6000 -14.9100
48 C1a C 32.2000 -16.3100
BOND 52
1 1 2 1
2 2 3 1
3 3 4 1
4 4 5 1
5 5 6 2
6 6 7 1
7 3 7 2
8 4 8 1
9 9 8 1 #Down
10 9 10 1
11 10 11 1
12 11 12 1
13 9 12 1
14 5 13 1
15 13 14 2
16 14 15 1
17 15 16 2
18 6 16 1
19 14 17 1
20 17 18 1
21 17 19 2
22 1 20 2
23 20 21 1
24 21 22 2
25 22 23 1
26 23 24 2
27 1 24 1
28 22 25 1
29 25 26 2
30 26 27 1
31 27 28 2
32 28 29 1
33 29 30 2
34 25 30 1
35 24 31 1
36 21 32 1
37 27 33 1
38 33 34 1
39 34 35 1
40 35 36 2
41 36 37 1
42 37 38 2
43 38 39 1
44 39 40 2
45 35 40 1
46 36 41 1
47 38 42 1
48 42 43 3
49 44 45 1
50 44 46 1
51 44 47 1
52 44 48 1
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