KEGG   DRUG: Linaprazan glurate
Entry
D13197                      Drug                                   
Name
Linaprazan glurate (USAN/INN)
Formula
C26H32N4O5
Exact mass
480.2373
Mol weight
480.56
Structure
Class
Gastrointestinal agent
 DG01975  Agents for peptic ulcer
  DG01646  Proton pump inhibitor (PPI)
Remark
Chemical structure group: DG03371
Efficacy
Proton pump inhibitor
Comment
Treatment of gastroesophageal reflux disease
Target
ATP4 [HSA:495 496] [KO:K01542 K01543]
  Pathway
hsa04966  Collecting duct acid secretion
hsa04971  Gastric acid secretion
Interaction
Brite
Drug groups [BR:br08330]
 Gastrointestinal agent
  DG01975  Agents for peptic ulcer
   DG01646  Proton pump inhibitor (PPI)
    DG03371  Linaprazan
     D13197  Linaprazan glurate
Target-based classification of drugs [BR:br08310]
 Enzymes
  Hydrolases (EC3)
   ATPase
    ATP4
     D13197  Linaprazan glurate (USAN/INN)
Drug groups [BR:br08330]
 Gastrointestinal agent
  DG01975  Agents for peptic ulcer
   DG01646  Proton pump inhibitor (PPI)
    DG03371  Linaprazan
Other DBs
CAS: 1228559-81-6
PubChem: 520621158
LinkDB
KCF data

ATOM        35
            1   C8y C    14.9989  -12.8441
            2   C8x C    14.9989  -14.1856
            3   C8y C    13.7281  -14.8916
            4   C8y C    12.4572  -14.1856
            5   N4y N    12.4572  -12.8441
            6   C8x C    13.7281  -12.1381
            7   N5x N    11.1158  -14.6092
            8   C8y C    10.3392  -13.5502
            9   C8y C    11.1158  -12.4205
            10  C1a C     8.9271  -13.5502
            11  C5a C    16.1991  -12.1381
            12  N1b N    17.3288  -12.8441
            13  O5a O    16.1991  -10.7261
            14  C1b C    18.5290  -12.1381
            15  N1b N    13.7281  -16.3036
            16  C1a C    10.6216  -11.0791
            17  C1b C    19.7292  -12.8441
            18  O7a O    20.9295  -12.1381
            19  C1b C    14.9283  -17.0097
            20  C8y C    14.9283  -18.4217
            21  C8y C    16.1285  -19.1277
            22  C8x C    16.1285  -20.5397
            23  C8x C    14.9283  -21.2458
            24  C8x C    13.7281  -20.5397
            25  C8y C    13.7281  -19.1277
            26  C1a C    17.3288  -18.4217
            27  C1a C    12.5278  -18.4217
            28  C7a C    22.1581  -12.8342
            29  C1b C    23.3496  -12.1331
            30  O6a O    22.0993  -14.2556
            31  C1b C    24.5654  -12.8219
            32  C1b C    25.7466  -12.1271
            33  C6a C    26.9675  -12.8190
            34  O6a O    28.1980  -12.0948
            35  O6a O    26.9786  -14.2560
BOND        37
            1     1   2 1
            2     2   3 2
            3     3   4 1
            4     4   5 1
            5     5   6 1
            6     1   6 2
            7     4   7 2
            8     7   8 1
            9     8   9 2
            10    5   9 1
            11    8  10 1
            12    1  11 1
            13   11  12 1
            14   11  13 2
            15   12  14 1
            16    3  15 1
            17    9  16 1
            18   14  17 1
            19   17  18 1
            20   15  19 1
            21   19  20 1
            22   20  21 2
            23   21  22 1
            24   22  23 2
            25   23  24 1
            26   24  25 2
            27   20  25 1
            28   21  26 1
            29   25  27 1
            30   18  28 1
            31   28  29 1
            32   28  30 2
            33   29  31 1
            34   31  32 1
            35   32  33 1
            36   33  34 1
            37   33  35 2

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