KEGG   DRUG: Linaprazan glurate hydrochloride
Entry
D13198                      Drug                                   
Name
Linaprazan glurate hydrochloride (USAN)
Formula
C26H32N4O5. HCl
Exact mass
516.2139
Mol weight
517.01
Structure
Class
Gastrointestinal agent
 DG01975  Agents for peptic ulcer
  DG01646  Proton pump inhibitor (PPI)
Remark
Chemical structure group: DG03371
Efficacy
Proton pump inhibitor
Comment
Treatment of gastroesophageal reflux disease
Target
ATP4 [HSA:495 496] [KO:K01542 K01543]
  Pathway
hsa04966  Collecting duct acid secretion
hsa04971  Gastric acid secretion
Interaction
Brite
Drug groups [BR:br08330]
 Gastrointestinal agent
  DG01975  Agents for peptic ulcer
   DG01646  Proton pump inhibitor (PPI)
    DG03371  Linaprazan
     D13198  Linaprazan glurate hydrochloride
Target-based classification of drugs [BR:br08310]
 Enzymes
  Hydrolases (EC3)
   ATPase
    ATP4
     D13198  Linaprazan glurate hydrochloride (USAN)
Drug groups [BR:br08330]
 Gastrointestinal agent
  DG01975  Agents for peptic ulcer
   DG01646  Proton pump inhibitor (PPI)
    DG03371  Linaprazan
Other DBs
CAS: 2770544-34-6
PubChem: 520621159
LinkDB
KCF data

ATOM        36
            1   C8y C    15.0095  -12.7753
            2   C8x C    15.0095  -14.1716
            3   C8y C    13.7529  -14.8697
            4   C8y C    12.4963  -14.1716
            5   N4y N    12.4963  -12.7753
            6   C8x C    13.7529  -12.0772
            7   N5x N    11.1699  -14.5904
            8   C8y C    10.4020  -13.5433
            9   C8y C    11.1699  -12.3565
            10  C1a C     9.0058  -13.5433
            11  C5a C    16.1963  -12.0772
            12  N1b N    17.3830  -12.7753
            13  O5a O    16.1963  -10.6810
            14  C1b C    18.5698  -12.0772
            15  N1b N    13.7529  -16.2659
            16  C1a C    10.6812  -11.0301
            17  C1b C    19.7566  -12.7753
            18  O7a O    20.9434  -12.0772
            19  C1b C    14.9397  -16.9640
            20  C8y C    14.9397  -18.3602
            21  C8y C    16.1264  -19.0583
            22  C8x C    16.1264  -20.4545
            23  C8x C    14.9397  -21.2224
            24  C8x C    13.7529  -20.4545
            25  C8y C    13.7529  -19.0583
            26  C1a C    17.3830  -18.3602
            27  C1a C    12.5661  -18.3602
            28  C7a C    22.2000  -12.7753
            29  C1b C    23.3868  -12.0772
            30  O6a O    22.1302  -14.2414
            31  C1b C    24.5735  -12.7753
            32  C1b C    25.7603  -12.0772
            33  C6a C    26.9471  -12.7753
            34  O6a O    28.2037  -12.0772
            35  O6a O    26.9471  -14.2414
            36  X   Cl   25.9000  -19.5300
BOND        37
            1     1   2 1
            2     2   3 2
            3     3   4 1
            4     4   5 1
            5     5   6 1
            6     1   6 2
            7     4   7 2
            8     7   8 1
            9     8   9 2
            10    5   9 1
            11    8  10 1
            12    1  11 1
            13   11  12 1
            14   11  13 2
            15   12  14 1
            16    3  15 1
            17    9  16 1
            18   14  17 1
            19   17  18 1
            20   15  19 1
            21   19  20 1
            22   20  21 2
            23   21  22 1
            24   22  23 2
            25   23  24 1
            26   24  25 2
            27   20  25 1
            28   21  26 1
            29   25  27 1
            30   18  28 1
            31   28  29 1
            32   28  30 2
            33   29  31 1
            34   31  32 1
            35   32  33 1
            36   33  34 1
            37   33  35 2

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