| Entry |
|
|---|
| Name |
Nafithromycin (INN) |
|---|
| Formula |
C42H62N6O11S
|
|---|
| Exact mass |
858.4197
|
|---|
| Mol weight |
859.04
|
|---|
| Structure |
|
|---|
| Class |
Antibacterial
DG01551 Macrolide antibiotic
|
|---|
| Remark |
|
|---|
| Efficacy |
Antibacterial, Protein biosynthesis inhibitor |
|---|
| Target |
50S ribosomal subunit |
|---|
| Interaction |
|
|---|
| Brite |
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
J ANTIINFECTIVES FOR SYSTEMIC USE
J01 ANTIBACTERIALS FOR SYSTEMIC USE
J01F MACROLIDES, LINCOSAMIDES AND STREPTOGRAMINS
J01FA Macrolides
J01FA17 Nafithromycin
D13243 Nafithromycin (INN)
Drug groups [BR:br08330]
Antibacterial
DG01551 Macrolide antibiotic
D13243 Nafithromycin
Antimicrobials [BR:br08307]
Antibacterials
Protein biosynthesis inhibitor
Macrolide
D13243 Nafithromycin (INN)
|
|---|
| Other DBs |
|
|---|
| LinkDB |
|
|---|
| KCF data |
ATOM 60
1 C5x C 18.4800 -18.0600
2 C1y C 18.4800 -16.7300
3 C1y C 17.2900 -18.7600
4 C1x C 17.2900 -16.0300
5 C1y C 17.2900 -20.0900
6 C1z C 17.2900 -14.6300
7 C1z C 16.1000 -20.7900
8 C1y C 16.1000 -14.0000
9 C1y C 14.9100 -20.0900
10 C1y C 14.9100 -14.6300
11 O7x O 14.9100 -18.7600
12 C5x C 14.9100 -16.0300
13 C7x C 13.7900 -18.0600
14 C1y C 13.7900 -16.7300
15 O6a O 12.6000 -18.7600
16 C1a C 12.6000 -16.0300
17 O5x O 16.1000 -16.7300
18 C1a C 13.7200 -13.9300
19 O2a O 16.1000 -12.6000
20 C1y C 14.9100 -11.9000
21 O2x O 13.7200 -12.6000
22 C1y C 12.4600 -11.9000
23 C1x C 12.4600 -10.5000
24 C1y C 13.6500 -9.8000
25 C1y C 14.9100 -10.5000
26 C1a C 11.2700 -12.6000
27 N1c N 13.6500 -8.4000
28 C1a C 12.4600 -7.7000
29 C1a C 14.8400 -7.7000
30 O1a O 16.1000 -9.8000
31 O2a O 18.4800 -13.9300
32 C1a C 18.5500 -15.3300
33 C1a C 18.4800 -12.5300
34 C1a C 19.7400 -16.6600
35 O5x O 19.6700 -18.7600
36 C1a C 16.1000 -18.0600
37 C1a C 14.9100 -21.4900
38 C1b C 13.7200 -20.7900
39 C1a C 12.5300 -20.0900
40 C1y C 18.3400 -21.0000
41 C7x C 17.7800 -22.2600
42 O7x O 16.3800 -22.1200
43 O6a O 18.4800 -23.4500
44 C2c C 19.7400 -21.0000
45 N1a N 20.4400 -19.8100
46 N2b N 20.4400 -22.1900
47 O2a O 21.8400 -22.1900
48 C1c C 22.5400 -21.0000
49 C8y C 23.9400 -21.0000
50 C1a C 21.8400 -19.8100
51 N5x N 24.7800 -19.8800
52 N5x N 26.1100 -20.3000
53 C8y C 26.1100 -21.7000
54 S2x S 24.7800 -22.1200
55 C8y C 27.2300 -22.5400
56 C8x C 28.4200 -21.8400
57 C8x C 29.6800 -22.6100
58 C8x C 29.6800 -24.0100
59 C8x C 28.4200 -24.6400
60 N5x N 27.2300 -23.9400
BOND 64
1 1 2 1
2 1 3 1
3 2 4 1
4 3 5 1
5 4 6 1
6 5 7 1
7 6 8 1
8 7 9 1
9 8 10 1
10 9 11 1
11 10 12 1
12 11 13 1
13 12 14 1
14 13 14 1
15 13 15 2
16 14 16 1 #Down
17 12 17 2
18 10 18 1 #Down
19 8 19 1 #Up
20 20 19 1 #Down
21 20 21 1
22 21 22 1
23 22 23 1
24 23 24 1
25 24 25 1
26 20 25 1
27 22 26 1 #Down
28 24 27 1 #Down
29 27 28 1
30 27 29 1
31 25 30 1 #Up
32 6 31 1 #Down
33 6 32 1 #Up
34 31 33 1
35 2 34 1 #Up
36 1 35 2
37 3 36 1 #Up
38 7 37 1 #Up
39 9 38 1 #Up
40 38 39 1
41 5 40 1
42 40 41 1
43 41 42 1
44 7 42 1
45 41 43 2
46 40 44 1 #Down
47 44 45 1
48 44 46 2
49 46 47 1
50 47 48 1
51 48 49 1
52 48 50 1 #Up
53 49 51 2
54 51 52 1
55 52 53 2
56 53 54 1
57 49 54 1
58 53 55 1
59 55 56 2
60 56 57 1
61 57 58 2
62 58 59 1
63 59 60 2
64 55 60 1
|
|---|
