| Entry |
|
|---|
| Name |
Aleniglipron (USAN/INN) |
|---|
| Formula |
C49H55FN9O6P
|
|---|
| Exact mass |
915.3997
|
|---|
| Mol weight |
915.99
|
|---|
| Structure |
|
|---|
| Class |
Antidiabetic agent
DG02044 Hypoglycemic agent
DG01493 GLP-1 receptor agonist
|
|---|
| Remark |
|
|---|
| Efficacy |
Antidiabetic, Antiobesity, Glucagon-like peptide 1 (GLP-1) receptor agonist |
|---|
| Comment |
Treatment of type 2 diabetes mellitus (T2DM) and obesity
|
|---|
| Target |
|
|---|
| Pathway |
| hsa04080 | Neuroactive ligand-receptor interaction |
|
|---|
| Interaction |
|
|---|
| Brite |
Drug groups [BR:br08330]
Antidiabetic agent
DG02044 Hypoglycemic agent
DG01493 GLP-1 receptor agonist
DG03376 Aleniglipron
D13248 Aleniglipron
Target-based classification of drugs [BR:br08310]
G Protein-coupled receptors
Secretin receptor family
Glucagon
GLP1R
D13248 Aleniglipron (USAN/INN)
Drug groups [BR:br08330]
Antidiabetic agent
DG02044 Hypoglycemic agent
DG01493 GLP-1 receptor agonist
DG03376 Aleniglipron
|
|---|
| Other DBs |
|
|---|
| LinkDB |
|
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| KCF data |
ATOM 66
1 C1x C 17.5549 -14.6873
2 N1y N 17.5549 -16.0861
3 C1y C 18.7438 -16.7855
4 C8y C 20.0028 -16.0861
5 C8y C 20.0028 -14.6873
6 C1x C 18.7438 -13.9879
7 C8y C 21.3316 -16.5058
8 N4y N 22.1009 -15.3867
9 N5x N 21.3316 -14.2677
10 C8y C 23.4997 -15.3867
11 C8x C 24.1991 -16.5757
12 C8y C 25.5979 -16.5757
13 C8y C 26.2973 -15.3867
14 C8y C 25.5979 -14.1978
15 C8x C 24.1991 -14.1978
16 C1a C 26.2973 -13.0088
17 X F 27.6961 -15.3867
18 C1a C 26.2973 -17.7647
19 N4y N 21.7512 -17.8346
20 C8x C 20.9120 -18.9537
21 C8x C 21.7512 -20.0727
22 N4y N 23.0801 -19.6531
23 C8y C 23.0801 -18.2543
24 O5x O 24.1991 -17.4150
25 C8y C 24.1991 -20.4923
26 C8x C 24.1991 -21.8911
27 C8x C 25.3881 -22.5905
28 C8y C 26.6470 -21.8911
29 C8y C 26.6470 -20.4923
30 C8x C 25.3881 -19.7929
31 C1a C 18.7438 -18.1843
32 C5a C 16.3659 -16.7855
33 C8y C 15.1769 -16.0861
34 O5a O 16.3659 -18.1843
35 C8x C 15.0370 -14.6873
36 C8y C 13.6382 -14.4076
37 C8y C 12.9388 -15.5966
38 N4y N 13.8481 -16.6456
39 C8x C 12.9388 -13.2186
40 C8y C 11.5401 -13.1487
41 C8x C 10.8407 -14.4076
42 C8x C 11.5401 -15.5966
43 C1y C 10.8407 -11.9597
44 C1x C 11.5401 -10.7707
45 C1x C 10.8407 -9.5118
46 O2x O 9.3719 -9.5118
47 C1x C 8.6725 -10.7008
48 C1x C 9.3719 -11.9597
49 C1z C 13.1487 -17.8346
50 C1x C 12.7990 -19.1635
51 C1y C 14.1278 -18.8138
52 C1a C 15.4567 -19.1635
53 C8y C 11.7499 -17.8346
54 N4x N 10.9106 -16.7156
55 C8y C 9.5817 -17.1352
56 O7x O 9.5817 -18.5340
57 N5x N 10.9106 -18.9537
58 O6a O 8.3928 -16.2960
59 N1b N 27.8627 -19.7768
60 C1a C 29.0930 -20.4731
61 P1a P 27.8790 -22.6159
62 C1b C 27.1719 -23.8292
63 O3b O 28.5816 -21.4103
64 C1b C 29.0914 -23.3159
65 C1a C 30.3277 -22.6019
66 C1a C 25.7602 -23.8238
BOND 75
1 1 2 1
2 2 3 1
3 3 4 1
4 4 5 1
5 5 6 1
6 1 6 1
7 4 7 2
8 7 8 1
9 8 9 1
10 5 9 2
11 8 10 1
12 10 11 2
13 11 12 1
14 12 13 2
15 13 14 1
16 14 15 2
17 10 15 1
18 14 16 1
19 13 17 1
20 12 18 1
21 7 19 1
22 19 20 1
23 20 21 2
24 21 22 1
25 22 23 1
26 19 23 1
27 23 24 2
28 22 25 1
29 25 26 2
30 26 27 1
31 27 28 2
32 28 29 1
33 29 30 2
34 25 30 1
35 3 31 1 #Down
36 2 32 1
37 32 33 1
38 32 34 2
39 33 35 2
40 35 36 1
41 36 37 1
42 37 38 1
43 33 38 1
44 36 39 2
45 39 40 1
46 40 41 2
47 41 42 1
48 37 42 2
49 43 40 1
50 43 44 1
51 44 45 1
52 45 46 1
53 46 47 1
54 47 48 1
55 43 48 1
56 49 38 1 #Down
57 50 51 1
58 51 49 1
59 49 50 1
60 51 52 1 #Up
61 49 53 1 #Up
62 53 54 1
63 54 55 1
64 55 56 1
65 56 57 1
66 53 57 2
67 55 58 2
68 29 59 1
69 59 60 1
70 28 61 1
71 61 62 1
72 61 63 2
73 61 64 1
74 64 65 1
75 62 66 1
|
|---|
