KEGG   DISEASE: Enterohemorrhagic Escherichia coli (EHEC) infection
H00277                      Disease                                

Enterohemorrhagic Escherichia coli (EHEC) infection
Enterohemorrhagic Escherichia coli (EHEC) infection is typically contracted through consumption of contaminated food or contact with contaminated water, animal feces or infected animals. EHEC is also referred to as verocytotoxin producing E. coli (VTEC) or Shiga toxin producing E. coli (STEC). The serotype O157:H7 is first associated with human disease after a multistate outbreak in the United States in 1982 involving contaminated hamburgers.
Infectious disease
Infectious diseases [BR:br08401]
 Bacterial infections
  Infections caused by enterobacteria
   H00277  Enterohemorrhagic Escherichia coli (EHEC) infection
Human diseases in ICD-11 classification [BR:br08403]
 01 Certain infectious or parasitic diseases
  Gastroenteritis or colitis of infectious origin
   Bacterial intestinal infections
    1A03  Intestinal infections due to Escherichia coli
     H00277  Enterohemorrhagic Escherichia coli (EHEC) infection
hsa05130  Pathogenic Escherichia coli infection
nt06121  TLR signaling (viruses and bacteria)
nt06123  TNF signaling (viruses and bacteria)
nt06125  Membrane trafficking (bacteria)
nt06131  Apoptosis (viruses and bacteria)
nt06135  Cytoskeletal regulation (viruses and bacteria)
nt06139  NLR signaling (viruses and bacteria)
N00926  Escherichia Tir to TLR2/4-MAPK signaling pathway
N00927  Escherichia/Shigella NleE/OspZ to TNF-NFKB signaling pathway
N00928  Escherichia NleB to TNF-NFKB signaling pathway
N00929  Escherichia NleC to TNF-NFKB signaling pathway
N00930  Escherichia NleD to TNF-JNK signaling pathway
N00931  Escherichia NleD to TNF-p38 signaling pathway
N00932  Escherichia NleH1 to TNF-NFKB signaling pathway
N00933  Escherichia NleA to NLRP3 inflammasome signaling pathway
N00935  Escherichia NleF to non-canonical inflammasome signaling pathway
N00936  Escherichia NleB1 to crosstalk between extrinsic and intrinsic apoptotic pathways
N00937  Escherichia NleF to extrinsic apoptotic pathway
N00938  Escherichia NleH to intrinsic apoptotic pathway
N00939  Escherichia EspF to intrinsic apoptotic pathway
N01084  Escherichia EspG to ARNO-ARF-ACTB/G signaling pathway
N01085  Escherichia EspG to ARNO-ARF-ACTB/G signaling pathway
N01086  Escherichia EspT to RAC signaling pathway
N01087  Escherichia EspW to RAC signaling pathway
N01088  Escherichia EspH to LPA-GNA12/13-RhoA signaling pathway
N01089  Escherichia EspM to LPA-GNA12/13-Rho signaling pathway
N01091  Escherichia EspJ to IGG-FCGR-RAC signaling pathway
N01092  Escherichia Eae/Tir to Actin signaling pathway
N01093  Escherichia EspJ/Tir to Actin signaling pathway
N01094  Escherichia Eae/Tir/TccP to Actin signaling pathway
N01095  Escherichia Map to LPA-GNA12/13-RhoA signaling pathway
N01096  Escherichia Map to CDC42 signaling pathway
N01286  Escherichia EspG to Microtubule-RHOA signaling pathway
N01288  Escherichia EspF to Tight junction-Actin signaling pathway
N01290  Escherichia NleA to COPII vesicle formation
N01292  Escherichia EspG to RAB1 signaling pathway
N01294  Escherichia NleF to COPI vesicle formation
Escherichia coli O157:H7 [GN:ece ecs ecf etw elx]
Escherichia coli O26:H11 [GN:eoj]
Escherichia coli O111:H- [GN:eoi]
Escherichia coli O103:H2 [GN:eoh]
Escherichia coli O104:H4 [GN:esl eso esm]
Escherichia coli O145:H28 [GN:ecoo ecoh]
M00542  EHEC/EPEC pathogenicity signature, T3SS and effectors
M00363  EHEC pathogenicity signature, Shiga toxin
Other DBs
ICD-11: 1A03.3
ICD-10: A04.3
MeSH: D004927
Baker DR, Moxley RA, Steele MB, Lejeune JT, Christopher-Hennings J, Chen DG, Hardwidge PR, Francis DH
Differences in virulence among Escherichia coli O157:H7 strains isolated from humans during disease outbreaks and from healthy cattle.
Appl Environ Microbiol 73:7338-46 (2007)
Ahmed SA, Awosika J, Baldwin C, Bishop-Lilly KA, Biswas B, Broomall S, Chain PS, Chertkov O, Chokoshvili O, Coyne S, Davenport K, Detter JC, Dorman W, Erkkila TH, Folster JP, Frey KG, George M, Gleasner C, Henry M, Hill KK, Hubbard K, Insalaco J, Johnson S, Kitzmiller A, Krepps M, Lo CC, Luu T, McNew LA, Minogue T, Munk CA, Osborne B, Patel M, Reitenga KG, Rosenzweig CN, Shea A, Shen X, Strockbine N, Tarr C, Teshima H, van Gieson E, Verratti K, Wolcott M, Xie G, Sozhamannan S, Gibbons HS
Genomic comparison of Escherichia coli O104:H4 isolates from 2009 and 2011 reveals plasmid, and prophage heterogeneity, including shiga toxin encoding phage stx2.
PLoS One 7:e48228 (2012)

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