KEGG   DISEASE: Tetanus
Entry
H00337                      Disease                                
Name
Tetanus
  Supergrp
Anaerobic infection [DS:H01410]
Description
Tetanus is a serious, often fatal intoxication caused by infection of Clostridium tetani, a gram-positive bacterium, through cuts or wounds. Mortality rate among untreated patients is high. Tetanus affects the muscles and nerves and manifests as muscle spasms in the jaw (lockjaw). Tetanus can be prevented by getting the tetanus vaccine.
Category
Bacterial infectious disease
Brite
Human diseases in ICD-11 classification [BR:br08403]
 01 Certain infectious or parasitic diseases
  Other bacterial diseases
   1C13  Tetanus
    H00337  Tetanus
Genome-based classification of infectious diseases [BR:br08401]
 Bacterial infections
  Infections caused by Gram-positive bacteria
   H00337  Tetanus
Infectious diseases by law in Japan [br08406.html]
 H00337
Pathogen
Clostridium tetani [GN:ctc ctet]
tetanus toxin (TeTx) [KO:K08644]
pore-forming toxin [KO:K06442 K11031 K11068]
Drug
Penicillin G potassium [DR:D01053]
Penicillin G sodium [DR:D05408]
Chlorpromazine hydrochloride [DR:D00789]
Other DBs
ICD-11: 1C13
MeSH: D013742
MedlinePlus: 000615
Reference
PMID:22111470
  Authors
Otero-Maldonado M, Bosques-Rosado M, Soto-Malave R, Deliz-Roldan B, Bertran-Pasarell J, Vargas Otero P
  Title
Tetanus is still present in the 21st century: case report and review of literature.
  Journal
Bol Asoc Med P R 103:41-7 (2011)
Reference
PMID:9416389
  Authors
Ernst ME, Klepser ME, Fouts M, Marangos MN
  Title
Tetanus: pathophysiology and management.
  Journal
Ann Pharmacother 31:1507-13 (1997)
DOI:10.1177/106002809703101211
Reference
PMID:18588497
  Authors
Brook I
  Title
Current concepts in the management of Clostridium tetani infection.
  Journal
Expert Rev Anti Infect Ther 6:327-36 (2008)
DOI:10.1586/14787210.6.3.327
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