Whipple disease (WD) is a rare chronic multi-system disease associated with the bacterium Tropheryma whipplei that is ubiquitously present in the environment. The clinical features of WD are non-specific and histological lesions in gastrointestinal system can be the major manifestations. Patients without symptoms of gastrointestinal disease might be insufficiently treated, resulting in a potentially fatal outcome such as endocarditis, neurological infection, osteoarticular infection, or uveitis.
Category
Bacterial infectious disease
Brite
Human diseases in ICD-11 classification [BR:br08403]
13 Diseases of the digestive system
Diseases of small intestine
DA96 Intestinal malabsorption or protein-losing enteropathy
H00352 Whipple disease
Genome-based classification of infectious diseases [BR:br08401]
Bacterial infections
Infections caused by actinobacteria
H00352 Whipple disease
