KEGG   DISEASE: Mpox (Monkeypox)
Entry
H00373                      Disease                                
Name
Mpox (Monkeypox)
Description
Human monkeypox is a rare viral zoonotic disease caused by Monkeypox virus of the genus Orthopoxvirus. It occurs mostly in the rain forests of central and western Africa. Human monkeypox has a clinical presentation similar to that of smallpox, including characteristic rash. Lymphadenopathy is not a common feature of smallpox and is therefore a key distinguishing feature of monkeypox. By contrast with smallpox, human monkeypox has low transmissibility between human beings.
Category
Viral infectious disease
Brite
Human diseases in ICD-11 classification [BR:br08403]
 01 Certain infectious or parasitic diseases
  Viral infections characterised by skin or mucous membrane lesions
   Infections due to poxvirus
    1E71  Monkeypox
     H00373  Mpox (Monkeypox)
Genome-based classification of infectious diseases [BR:br08401]
 Viral infections
  Infections caused by dsDNA viruses
   H00373  Mpox (Monkeypox)
Pathogen
Monkeypox virus [GN:T40083]
Comment
Many animals are infected with monkeypox virus under natural conditions, including squirrels, non-human primates, and rats. However, the primary reservoir for human infection remains unknown.
Other DBs
ICD-11: 1E71
ICD-10: B04
MeSH: D045908
Reference
PMID:6304185
  Authors
Jezek Z, Gromyko AI, Szczeniowski MV
  Title
Human monkeypox.
  Journal
J Hyg Epidemiol Microbiol Immunol 27:13-28 (1983)
Reference
  Authors
Nalca A, Rimoin AW, Bavari S, Whitehouse CA
  Title
Reemergence of monkeypox: prevalence, diagnostics, and countermeasures.
  Journal
Clin Infect Dis 41:1765-71 (2005)
DOI:10.1086/498155
Reference
  Authors
Parker S, Nuara A, Buller RM, Schultz DA
  Title
Human monkeypox: an emerging zoonotic disease.
  Journal
Future Microbiol 2:17-34 (2007)
DOI:10.2217/17460913.2.1.17
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