KEGG   DISEASE: Toxoplasmosis
Entry
H00435                      Disease                                
Name
Toxoplasmosis
Description
Toxoplasmosis is a worldwide infection caused by the intracellular parasite Toxoplasma gondii. The majority of horizontal transmissions to humans is caused either by the ingestion of tissue cysts in infected meat or by the ingestion of soil, water, or food contaminated with sporulated oocysts derived from the environment or, less frequently, directly from feline feces. The parasite usually causes asymptomatic infection but in immunocompromised individuals, it can result in fatal disease with encephalitis. Transmission can also occur vertically. Congenital infection causes spontaneous abortion or serious defects such as hydrocephalus, chorioretinitis, and intracranial calcification in infants.
Category
Infectious disease
Brite
Infectious diseases [BR:br08401]
 Parasitic infections (protists)
  Infections caused by Alveolates
   H00435  Toxoplasmosis
Human diseases in ICD-11 classification [BR:br08403]
 01 Certain infectious or parasitic diseases
  Parasitic diseases
   Nonintestinal protozoal diseases
    1F57  Toxoplasmosis
     H00435  Toxoplasmosis
Pathway
hsa05145  Toxoplasmosis
Pathogen
Toxoplasma gondii [GN:tgo]
Drug
Sulfadiazine [DR:D00587]
Pyrimethamine [DR:D00488]
Comment
Definitive host: Felis silvestris catus
Other DBs
ICD-11: 1F57
ICD-10: B58
MeSH: D014123
Reference
  Authors
Hosseini SA, Amouei A, Sharif M, Sarvi S, Galal L, Javidnia J, Pagheh AS, Gholami S, Mizani A, Daryani A
  Title
Human toxoplasmosis: a systematic review for genetic diversity of Toxoplasma gondii in clinical samples.
  Journal
Epidemiol Infect 1-9 (2018)
DOI:10.1017/S0950268818002947
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