KEGG   DISEASE: Obsessive-Compulsive and Related Disorder
Entry
H01453                      Disease                                
Name
Obsessive-Compulsive and Related Disorder
Description
Obsessive-Compulsive and Related Disorder (OCRD) is a group of disorders that is characterized by having preoccupations (obsessions) and/or repetitive behaviors (compulsions). Previously, Obsessive-compulsive disorder (OCD) was grouped with the anxiety disorders. However, the fifth edition of the Diagnostic and Statistical Manual of Mental Disorders (DSM-5) moved OCD into a new category, because much of the evidence suggests OCD and OC-spectrum disorders are distinct from other anxiety disorders. Although OCD and anxiety disorders often share core clinical feature, significant differences also exist in effective first-line pharmacological interventions. Patients with anxiety disorders respond to a wide range of pharmacological interventions. In contrast, patients with OCD do not respond to nonserotonergic agents. OCRD includes OCD, Trichotillomania, Hoarding disorder, Excoriation disorder, and Body dysmorphic disorder.
The usual treatments of OCRD are cognitive behavioural therapy (CBT) and selective serotonin reuptake inhibitors (SSRI).
Category
Mental and behavioural disorder
Brite
Human diseases [BR:br08402]
 Other diseases
  Mental and behavioural disorders
   H01453  Obsessive-Compulsive and Related Disorder
Human diseases in ICD-11 classification [BR:br08403]
 06 Mental, behavioural or neurodevelopmental disorders
  Obsessive-compulsive or related disorders
   6B2Z  Obsessive-compulsive or related disorders, unspecified
    H01453  Obsessive-Compulsive and Related Disorder
Comment
See also H01450 Obsessive-compulsive disorder (OCD), H00864 Trichotillomania, H01448 Hoarding disorder, H01449 Excoriation disorder, and H01447 Body Dysmorphic Disorder.
Other DBs
ICD-11: 6B2Z
ICD-10: F42
Reference
  Authors
Van Ameringen M, Patterson B, Simpson W
  Title
DSM-5 obsessive-compulsive and related disorders: clinical implications of new criteria.
  Journal
Depress Anxiety 31:487-93 (2014)
DOI:10.1002/da.22259
Reference
  Authors
Murphy DL, Timpano KR, Wheaton MG, Greenberg BD, Miguel EC
  Title
Obsessive-compulsive disorder and its related disorders: a reappraisal of obsessive-compulsive spectrum concepts.
  Journal
Dialogues Clin Neurosci 12:131-48 (2010)
Reference
  Authors
Nicolini H, Arnold P, Nestadt G, Lanzagorta N, Kennedy JL
  Title
Overview of genetics and obsessive-compulsive disorder.
  Journal
Psychiatry Res 170:7-14 (2009)
DOI:10.1016/j.psychres.2008.10.011
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