KEGG   DISEASE: Acute heart failure
Entry
H01631                      Disease                                
Name
Acute heart failure
  Subgroup
Sudden cardiac failure, infantile (SCFI)
Sudden cardiac failure, alcohol-induced (SCFAI)
Description
Acute heart failure (AHF) can be defined as a heterogeneous syndrome of signs and symptoms of new-onset or gradual/rapidly worsening heart failure (HF), requiring urgent therapy. Intrinsic cardiac abnormalities and comorbid conditions, including lung and renal disease, and sleep-disordered breathing, can contribute to the development of AHF. Factors triggering AHF may include ischemia, hypertension, arrhythmias, noncardiac comorbidities, and administered drugs, etc. Because of the poor clinical outcome and the relevant associated morbidity and mortality, it remains a major public health issue with a substantial socioeconomic burden.
Category
Cardiovascular disease
Brite
Human diseases in ICD-11 classification [BR:br08403]
 11 Diseases of the circulatory system
  Heart failure
   BD1Y  Other specified heart failure
    H01631  Acute heart failure
Gene
PPA2 [HSA:27068] [KO:K01507]
Drug
Milrinone lactate [DR:D02085]
Sodium nitroprusside [DR:D00614]
Other DBs
ICD-11: BD1Y
MeSH: D006333
OMIM: 617222 617223
Reference
  Authors
Mentz RJ, O'Connor CM
  Title
Pathophysiology and clinical evaluation of acute heart failure.
  Journal
Nat Rev Cardiol 13:28-35 (2016)
DOI:10.1038/nrcardio.2015.134
Reference
  Authors
Ponikowski P, Jankowska EA
  Title
Pathogenesis and clinical presentation of acute heart failure.
  Journal
Rev Esp Cardiol (Engl Ed) 68:331-7 (2015)
DOI:10.1016/j.rec.2015.02.001
Reference
  Authors
Chowdhury P, Kehl D, Choudhary R, Maisel A
  Title
The use of biomarkers in the patient with heart failure.
  Journal
Curr Cardiol Rep 15:372 (2013)
DOI:10.1007/s11886-013-0372-4
Reference
PMID:27523597 (SCFI_SCFAI)
  Authors
Kennedy H, Haack TB, Hartill V, Matakovic L, Baumgartner ER, Potter H, Mackay R, Alston CL, O'Sullivan S, McFarland R, Connolly G, Gannon C, King R, Mead S, Crozier I, Chan W, Florkowski CM, Sage M, Hofken T, Alhaddad B, Kremer LS, Kopajtich R, Feichtinger RG, Sperl W, Rodenburg RJ, Minet JC, Dobbie A, Strom TM, Meitinger T, George PM, Johnson CA, Taylor RW, Prokisch H, Doudney K, Mayr JA
  Title
Sudden Cardiac Death Due to Deficiency of the Mitochondrial Inorganic Pyrophosphatase PPA2.
  Journal
Am J Hum Genet 99:674-682 (2016)
DOI:10.1016/j.ajhg.2016.06.027
Reference
PMID:27523598 (SCFI)
  Authors
Guimier A, Gordon CT, Godard F, Ravenscroft G, Oufadem M, Vasnier C, Rambaud C, Nitschke P, Bole-Feysot C, Masson C, Dauger S, Longman C, Laing NG, Kugener B, Bonnet D, Bouvagnet P, Di Filippo S, Probst V, Redon R, Charron P, Rotig A, Lyonnet S, Dautant A, de Pontual L, di Rago JP, Delahodde A, Amiel J
  Title
Biallelic PPA2 Mutations Cause Sudden Unexpected Cardiac Arrest in Infancy.
  Journal
Am J Hum Genet 99:666-673 (2016)
DOI:10.1016/j.ajhg.2016.06.021
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