KEGG DISEASE: Familial ventricular tachycardia

KEGG

DISEASE: Familial ventricular tachycardia

Entry

H02269                      Disease

Name

Familial ventricular tachycardia

Description

Sudden cardiac death resulting from ventricular tachyarrhythmia represents a major healthcare issue. Familial ventricular tachycardia is usually attributable to recognized conditions such as arrhythmogenic right ventricular dysplasia, hypertrophic cardiomyopathy, familial cardiomyopathy or one of the long QT interval syndromes. However, some patients had no specific electrocardiographic (ECG) changes. Their QT intervals were normal and showed no cardiac abnormalities. It has been reported that absence of the inhibitory G-Protein (G alpha i-2) predisposes to ventricular tachycardia.

Category

Cardiovascular disease

Brite

Human diseases in ICD-11 classification [BR:br08403]
11 Diseases of the circulatory system
  Cardiac arrhythmia
   Ventricular rhythm disturbance
    BC71  Ventricular tachyarrhythmia
     H02269  Familial ventricular tachycardia

Gene

GNAI2 [HSA:2771] [KO:K04630]

Other DBs

ICD-11:

MeSH:

OMIM:

Reference

Authors

Fisher JD, Krikler D, Hallidie-Smith KA

Title

Familial polymorphic ventricular arrhythmias: a quarter century of successful medical treatment based on serial exercise-pharmacologic testing.

Journal

J Am Coll Cardiol 34:2015-22 (1999)
DOI:10.1016/S0735-1097(99)00438-6

Reference

Authors

Zuberi Z, Nobles M, Sebastian S, Dyson A, Lim SY, Breckenridge R, Birnbaumer L, Tinker A

Title

Absence of the inhibitory G-protein Galphai2 predisposes to ventricular cardiac arrhythmia.

Journal

Circ Arrhythm Electrophysiol 3:391-400 (2010)
DOI:10.1161/CIRCEP.109.894329

LinkDB

» Japanese version

DBGET integrated database retrieval system