KEGG   DISEASE: Actinic keratosis
Entry
H02429                      Disease                                
Name
Actinic keratosis
Description
Actinic keratosis (AK) is a common cutaneous lesion associated with chronic exposure to ultraviolet (UV) radiation. AK presents scaly, erythematous papule or plaque and is considered the earliest clinically recognizable manifestation of squamous cell carcinoma.
Category
Skin disease
Brite
Human diseases in ICD-11 classification [BR:br08403]
 14 Diseases of the skin
  Disorders of the skin of uncertain or unpredictable malignant potential
   EK90  Actinic keratosis and other discrete epidermal dysplasias
    H02429  Actinic keratosis
Drug
Imiquimod [DR:D02500]
Ingenol mebutate [DR:D09393]
Tirbanibulin [DR:D11691]
Aminolevulinic acid hydrochloride [DR:D02908]
Other DBs
ICD-11: EK90.0
ICD-10: L57.0
MeSH: D055623
OMIM: 148390
Reference
PMID:27500794
  Authors
Siegel JA, Korgavkar K, Weinstock MA
  Title
Current perspective on actinic keratosis: a review.
  Journal
Br J Dermatol 177:350-358 (2017)
DOI:10.1111/bjd.14852
Reference
PMID:25371768
  Authors
Goldenberg G, Perl M
  Title
Actinic keratosis: update on field therapy.
  Journal
J Clin Aesthet Dermatol 7:28-31 (2014)
Reference
PMID:2757930
  Authors
Atherton DJ, Botcherby PK, Francis AJ, Smith NP, Wells RS, Giannelli F
  Title
Familial keratoses of actinic distribution associated with internal malignancy and cellular hypersensitivity to UVA.
  Journal
Br J Dermatol 120:671-81 (1989)
DOI:10.1111/j.1365-2133.1989.tb01355.x
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