KEGG   NETWORK: N01234
Entry
N01234                      Network                                

Name
CXCL1/5/8 to KSHV vGPCR signaling
Definition
(CXCL1,CXCL5,CXCL8) -> vGPCR
  Expanded
(2919,6374,3576) -> K21667
Class
nt06150 Cytokine-cytokine receptor interaction (viruses)
Type
Pathogen
Pathway
hsa04061  Viral protein interaction with cytokine and cytokine receptor
Disease
H00041  Kaposi sarcoma
Gene
2919  CXCL1; C-X-C motif chemokine ligand 1
6374  CXCL5; C-X-C motif chemokine ligand 5
3576  CXCL8; C-X-C motif chemokine ligand 8
Perturbant
K21667 (vGPCR)  vGPCR; KSHV G-protein coupled receptor
Reference
  Authors
Pontejo SM, Murphy PM
  Title
Chemokines encoded by herpesviruses.
  Journal
J Leukoc Biol 102:1199-1217 (2017)
DOI:10.1189/jlb.4RU0417-145RR
Reference
  Authors
de Munnik SM, Smit MJ, Leurs R, Vischer HF
  Title
Modulation of cellular signaling by herpesvirus-encoded G protein-coupled receptors.
  Journal
Front Pharmacol 6:40 (2015)
DOI:10.3389/fphar.2015.00040
Reference
  Authors
Vischer HF, Siderius M, Leurs R, Smit MJ
  Title
Herpesvirus-encoded GPCRs: neglected players in inflammatory and proliferative diseases?
  Journal
Nat Rev Drug Discov 13:123-39 (2014)
DOI:10.1038/nrd4189
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