KEGG   NETWORK: N01254
Entry
N01254                      Network                                
Name
HIV gp120 to CXCR4 signaling
Definition
gp120 -> CXCR4
  Expanded
K19287 -> 7852
Class
nt06150 Cytokine-cytokine receptor interaction (viruses)
Type
Pathogen
Pathway
hsa04061  Viral protein interaction with cytokine and cytokine receptor
Disease
H01563  HIV infection
Gene
7852  CXCR4; C-X-C motif chemokine receptor 4
Perturbant
K19287 (gp120)  gp160; HIV-1 envelope glycoprotein gp160
Reference
  Authors
Lee C, Liu QH, Tomkowicz B, Yi Y, Freedman BD, Collman RG
  Title
Macrophage activation through CCR5- and CXCR4-mediated gp120-elicited signaling pathways.
  Journal
J Leukoc Biol 74:676-82 (2003)
DOI:10.1189/jlb.0503206
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