KEGG   DISEASE: Leptospirosis
Entry
H00355                      Disease                                

Name
Leptospirosis;
Weil disease
Description
Leptospirosis is a zoonosis, caused by pathogenic spirochetes belonging to the genus Leptospira. Many mammalian species and amphibians may act as reservoirs. Leptospira colonize the renal tubules of chronically infected reservoir animals and are shed via urine into the environment, and then usually gain entry to the host via mucosal surfaces or damaged skin. Clinical symptoms range from a self-resolving acute febrile illness to severe, sometimes fatal disease (Weil disease).
Category
Infectious disease
Brite
Infectious diseases [BR:br08401]
 Bacterial infections
  Infections caused by spirochaetes
   H00355  Leptospirosis
Human diseases in ICD-11 classification [BR:br08403]
 01 Certain infectious or parasitic diseases
  Certain zoonotic bacterial diseases
   1B91  Leptospirosis
    H00355  Leptospirosis
Pathogen
Leptospira interrogans [GN:lil lic lis]
Leptospira borgpetersenii [GN:lbj lbl]
Leptospira santarosai [GN:lst]
Leptospira kmetyi [GN:lkm]
Other DBs
ICD-11: 1B91
ICD-10: A27
MeSH: D007922
MedlinePlus: 001376
Reference
  Authors
Lehmann JS, Matthias MA, Vinetz JM, Fouts DE
  Title
Leptospiral pathogenomics.
  Journal
Pathogens 3:280-308 (2014)
DOI:10.3390/pathogens3020280
Reference
  Authors
Levett PN
  Title
Leptospirosis.
  Journal
Clin Microbiol Rev 14:296-326 (2001)
DOI:10.1128/CMR.14.2.296-326.2001
Reference
  Authors
Lim VK
  Title
Leptospirosis: a re-emerging infection.
  Journal
Malays J Pathol 33:1-5 (2011)
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