KEGG   DISEASE: Cryptosporidiosis
Entry
H00356                      Disease                                
Name
Cryptosporidiosis
Description
Human cryptosporidiosis is a self-limited diarrheal disease characterized by acute, persistent, or chronic diarrhea and biliary/pulmonary disease. Transmission of the causative agent, Cryptosporidium, occurs by the fecal-oral route. Water-borne transmission often occurs. The disease can be potentially serious in immunocompromised patients.
Category
Parasitic infectious disease
Brite
Human diseases in ICD-11 classification [BR:br08403]
 01 Certain infectious or parasitic diseases
  Gastroenteritis or colitis of infectious origin
   Protozoal intestinal infections
    1A32  Cryptosporidiosis
     H00356  Cryptosporidiosis
Genome-based classification of infectious diseases [BR:br08401]
 Parasitic infections (protists)
  Infections caused by Alveolates
   H00356  Cryptosporidiosis
Pathogen
Cryptosporidium parvum [GN:cpv]
Cryptosporidium hominis [GN:cho]
Drug
Nitazoxanide [DR:D02486]
Comment
The most important therapy is hydroelectrolytic resuscitation. Antiretroviral therapy appears to play a critical role in resolution of AIDS-associated cryptosporidiosis.
Other DBs
ICD-11: 1A32
ICD-10: A07.2
MeSH: D003457
MedlinePlus: 000617
Reference
  Authors
Collinet-Adler S, Ward HD
  Title
Cryptosporidiosis: environmental, therapeutic, and preventive challenges.
  Journal
Eur J Clin Microbiol Infect Dis 29:927-35 (2010)
DOI:10.1007/s10096-010-0960-9
Reference
  Authors
Chappell CL, Okhuysen PC
  Title
Cryptosporidiosis.
  Journal
Curr Opin Infect Dis 15:523-7 (2002)
DOI:10.1097/00001432-200210000-00012
Reference
  Authors
Cabada MM, White AC Jr
  Title
Treatment of cryptosporidiosis: do we know what we think we know?
  Journal
Curr Opin Infect Dis 23:494-9 (2010)
DOI:10.1097/QCO.0b013e32833de052
Reference
  Authors
McDonald V
  Title
Cryptosporidiosis: host immune responses and the prospects for effective immunotherapies.
  Journal
Expert Rev Anti Infect Ther 9:1077-86 (2011)
DOI:10.1586/eri.11.123
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