KEGG   DISEASE: Aggregatibacter aphrophilus infection
Entry
H01068                      Disease                                
Name
Aggregatibacter aphrophilus infection
Description
Aggregatibacter aphrophilus (formerly Haemophilus aphrophilus) is a capnophilic, fermentative, non-motile, gram-negative coccobacillus, that is part of the indigenous microbiota of the human oropharynx. Infections with this bacterium are infrequent. It has mainly been associated with endocarditis, brain abscesses, vertebral osteomyelitis, and bacteremia.
Category
Bacterial infectious disease
Brite
Genome-based classification of infectious diseases [BR:br08401]
 Bacterial infections
  Infections caused by other gamma proteobacteria
   H01068  Aggregatibacter aphrophilus infection
Pathogen
Aggregatibacter aphrophilus [GN:aap]
Comment
Resistance to ampicillin, cefuroxime, ceftazidime and cefotaxime has been reported, with clinical failure of treatment with third-generation cephalosporins.
Reference
PMID:6816135
  Authors
Albritton WL
  Title
Infections due to Haemophilus species other than H. influenzae.
  Journal
Annu Rev Microbiol 36:199-216 (1982)
DOI:10.1146/annurev.mi.36.100182.001215
Reference
  Authors
Colson P, La Scola B, Champsaur P
  Title
Vertebral infections caused by Haemophilus aphrophilus: case report and review.
  Journal
Clin Microbiol Infect 7:107-13 (2001)
DOI:10.1046/j.1469-0691.2001.00208.x
Reference
PMID:8170429
  Authors
Wilson CM, Reiss-Levy EA, Sturgess AD, Au TC
  Title
Haemophilus paraphrophilus vertebral osteomyelitis.
  Journal
Med J Aust 160:512-4 (1994)
DOI:10.5694/j.1326-5377.1994.tb138318.x
Reference
PMID:3308306
  Authors
Papasian CJ, Reintjes S, Rengachary SS, Neihart RE, Hodges GR
  Title
Haemophilus paraphrophilus brain abscess.
  Journal
Diagn Microbiol Infect Dis 7:205-9 (1987)
DOI:10.1016/0732-8893(87)90006-X
Reference
PMID:7620027
  Authors
Coll-Vinent B, Suris X, Lopez-Soto A, Miro JM, Coca A
  Title
Haemophilus paraphrophilus endocarditis: case report and review.
  Journal
Clin Infect Dis 20:1381-3 (1995)
DOI:10.1093/clinids/20.5.1381
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