KEGG   DISEASE: Lymphatic filariasis
Entry
H01086                      Disease                                
Name
Lymphatic filariasis
  Supergrp
Filariasis [DS:H02028]
Description
Lymphatic filariasis is a mosquito-borne parasitic nematode infection in tropical and subtropical areas of Asia, Africa, the Western Pacific, and some parts of the Americas. Disease pathogenesis is linked to host inflammation invoked by the death of the adult parasite, manifesting as recurrent debilitating fevers, hydrocoeles, lymphangitis and lymphadenitis, and elephantiasis.
Category
Parasitic infectious disease
Brite
Human diseases in ICD-11 classification [BR:br08403]
 01 Certain infectious or parasitic diseases
  Parasitic diseases
   Helminthiases
    Diseases due to nematodes
     1F66  Filariasis
      H01086  Lymphatic filariasis
Genome-based classification of infectious diseases [BR:br08401]
 Parasitic infections (animals)
  Infections caused by nematodes
   H01086  Lymphatic filariasis
Pathogen
Wuchereria bancrofti
Brugia malayi [GN:bmy]
Brugia timori
Comment
Vectors: Mosquitos including Anopheles, Aedes, Culex, Mansonia, and Ochlerotatus
Other DBs
ICD-11: 1F66.3
MeSH: D004605
Reference
PMID:20739055
  Authors
Taylor MJ, Hoerauf A, Bockarie M
  Title
Lymphatic filariasis and onchocerciasis.
  Journal
Lancet 376:1175-85 (2010)
DOI:10.1016/S0140-6736(10)60586-7
Reference
PMID:21722251
  Authors
Hoerauf A, Pfarr K, Mand S, Debrah AY, Specht S
  Title
Filariasis in Africa--treatment challenges and prospects.
  Journal
Clin Microbiol Infect 17:977-85 (2011)
DOI:10.1111/j.1469-0691.2011.03586.x
Reference
PMID:20847694
  Authors
Bockarie MJ, Deb RM
  Title
Elimination of lymphatic filariasis: do we have the drugs to complete the job?
  Journal
Curr Opin Infect Dis 23:617-20 (2010)
DOI:10.1097/QCO.0b013e32833fdee5
Reference
PMID:18798707
  Authors
Bockarie MJ, Pedersen EM, White GB, Michael E
  Title
Role of vector control in the global program to eliminate lymphatic filariasis.
  Journal
Annu Rev Entomol 54:469-87 (2009)
DOI:10.1146/annurev.ento.54.110807.090626
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