KEGG Pathway Maps

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 Metabolism
   Global and overview maps
     01100  Metabolic pathways
     01110  Biosynthesis of secondary metabolites
     01120  Microbial metabolism in diverse environments
     01200  Carbon metabolism
     01210  2-Oxocarboxylic acid metabolism
     01212  Fatty acid metabolism
     01230  Biosynthesis of amino acids
     01232  Nucleotide metabolism
     01250  Biosynthesis of nucleotide sugars
     01240  Biosynthesis of cofactors
     01220  Degradation of aromatic compounds
     01310  Nitrogen cycle
     01320  Sulfur cycle
   Carbohydrate metabolism
     00010  Glycolysis / Gluconeogenesis
     00020  Citrate cycle (TCA cycle)
     00030  Pentose phosphate pathway
     00040  Pentose and glucuronate interconversions
     00051  Fructose and mannose metabolism
     00052  Galactose metabolism
     00053  Ascorbate and aldarate metabolism
     00500  Starch and sucrose metabolism
     00620  Pyruvate metabolism
     00630  Glyoxylate and dicarboxylate metabolism
     00640  Propanoate metabolism
     00650  Butanoate metabolism
     00660  C5-Branched dibasic acid metabolism
     00562  Inositol phosphate metabolism
     00566  Sulfoquinovose metabolism
   Energy metabolism
     00190  Oxidative phosphorylation
     00195  Photosynthesis
     00196  Photosynthesis - antenna proteins
     00710  Carbon fixation by Calvin cycle
     00720  Other carbon fixation pathways
     00680  Methane metabolism
     00910  Nitrogen metabolism
     00920  Sulfur metabolism
   Lipid metabolism
     00061  Fatty acid biosynthesis
     00062  Fatty acid elongation
     00071  Fatty acid degradation
     00073  Cutin, suberine and wax biosynthesis
     00074  Mycolic acid biosynthesis
     00100  Steroid biosynthesis
     00120  Primary bile acid biosynthesis
     00121  Secondary bile acid biosynthesis
     00140  Steroid hormone biosynthesis
     00561  Glycerolipid metabolism
     00564  Glycerophospholipid metabolism
     00565  Ether lipid metabolism
     00600  Sphingolipid metabolism
     00590  Arachidonic acid metabolism
     00591  Linoleic acid metabolism
     00592  alpha-Linolenic acid metabolism
     01040  Biosynthesis of unsaturated fatty acids
   Nucleotide metabolism
     00230  Purine metabolism
     00240  Pyrimidine metabolism
   Amino acid metabolism
     00250  Alanine, aspartate and glutamate metabolism
     00260  Glycine, serine and threonine metabolism
     00270  Cysteine and methionine metabolism
     00280  Valine, leucine and isoleucine degradation
     00290  Valine, leucine and isoleucine biosynthesis
     00300  Lysine biosynthesis
     00310  Lysine degradation
     00220  Arginine biosynthesis
     00330  Arginine and proline metabolism
     00340  Histidine metabolism
     00350  Tyrosine metabolism
     00360  Phenylalanine metabolism
     00380  Tryptophan metabolism
     00400  Phenylalanine, tyrosine and tryptophan biosynthesis
   Metabolism of other amino acids
     00410  beta-Alanine metabolism
     00430  Taurine and hypotaurine metabolism
     00440  Phosphonate and phosphinate metabolism
     00450  Selenocompound metabolism
     00460  Cyanoamino acid metabolism
     00470  D-Amino acid metabolism
     00480  Glutathione metabolism
   Glycan biosynthesis and metabolism
     00520  Amino sugar and nucleotide sugar metabolism
     00541  Biosynthesis of various nucleotide sugars
     00510  N-Glycan biosynthesis
     00513  Various types of N-glycan biosynthesis
     00512  Mucin type O-glycan biosynthesis
     00515  Mannose type O-glycan biosynthesis
     00514  Other types of O-glycan biosynthesis
     00532  Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate
     00534  Glycosaminoglycan biosynthesis - heparan sulfate / heparin
     00533  Glycosaminoglycan biosynthesis - keratan sulfate
     00531  Glycosaminoglycan degradation
     00563  Glycosylphosphatidylinositol (GPI)-anchor biosynthesis
     00601  Glycosphingolipid biosynthesis - lacto and neolacto series
     00603  Glycosphingolipid biosynthesis - globo and isoglobo series
     00604  Glycosphingolipid biosynthesis - ganglio series
     00511  Other glycan degradation
     00540  Lipopolysaccharide biosynthesis
     00542  O-Antigen repeat unit biosynthesis
     00550  Peptidoglycan biosynthesis
     00552  Teichoic acid biosynthesis
     00571  Lipoarabinomannan (LAM) biosynthesis
     00572  Arabinogalactan biosynthesis - Mycobacterium
     00543  Exopolysaccharide biosynthesis
   Metabolism of cofactors and vitamins
     00730  Thiamine metabolism
     00740  Riboflavin metabolism
     00750  Vitamin B6 metabolism
     00760  Nicotinate and nicotinamide metabolism
     00770  Pantothenate and CoA biosynthesis
     00780  Biotin metabolism
     00785  Lipoic acid metabolism
     00790  Folate biosynthesis
     00670  One carbon pool by folate
     00830  Retinol metabolism
     00860  Porphyrin metabolism
     00130  Ubiquinone and other terpenoid-quinone biosynthesis
   Metabolism of terpenoids and polyketides
     00900  Terpenoid backbone biosynthesis
     00902  Monoterpenoid biosynthesis
     00909  Sesquiterpenoid and triterpenoid biosynthesis
     00904  Diterpenoid biosynthesis
     00906  Carotenoid biosynthesis
     00905  Brassinosteroid biosynthesis
     00981  Insect hormone biosynthesis
     00908  Zeatin biosynthesis
     00903  Limonene degradation
     00907  Pinene, camphor and geraniol degradation
     01052  Type I polyketide structures
     00522  Biosynthesis of 12-, 14- and 16-membered macrolides
     01051  Biosynthesis of ansamycins
     01059  Biosynthesis of enediyne antibiotics
     01056  Biosynthesis of type II polyketide backbone
     01057  Biosynthesis of type II polyketide products
     00253  Tetracycline biosynthesis
     00523  Polyketide sugar unit biosynthesis
     01054  Nonribosomal peptide structures
     01053  Biosynthesis of siderophore group nonribosomal peptides
     01055  Biosynthesis of vancomycin group antibiotics
   Biosynthesis of other secondary metabolites
     00940  Phenylpropanoid biosynthesis
     00945  Stilbenoid, diarylheptanoid and gingerol biosynthesis
     00941  Flavonoid biosynthesis
     00944  Flavone and flavonol biosynthesis
     00942  Anthocyanin biosynthesis
     00943  Isoflavonoid biosynthesis
     00946  Degradation of flavonoids
     00901  Indole alkaloid biosynthesis
     00403  Indole diterpene alkaloid biosynthesis
     00950  Isoquinoline alkaloid biosynthesis
     00960  Tropane, piperidine and pyridine alkaloid biosynthesis
     00996  Biosynthesis of various alkaloids
     00232  Caffeine metabolism
     00965  Betalain biosynthesis
     00966  Glucosinolate biosynthesis
     00402  Benzoxazinoid biosynthesis
     00311  Penicillin and cephalosporin biosynthesis
     00332  Carbapenem biosynthesis
     00261  Monobactam biosynthesis
     00331  Clavulanic acid biosynthesis
     00521  Streptomycin biosynthesis
     00524  Neomycin, kanamycin and gentamicin biosynthesis
     00525  Acarbose and validamycin biosynthesis
     00401  Novobiocin biosynthesis
     00404  Staurosporine biosynthesis
     00405  Phenazine biosynthesis
     00333  Prodigiosin biosynthesis
     00254  Aflatoxin biosynthesis
     00975  Biosynthesis of various siderophores
     00998  Biosynthesis of various antibiotics
     00999  Biosynthesis of various plant secondary metabolites
     00997  Biosynthesis of various other secondary metabolites
   Xenobiotics biodegradation and metabolism
     00362  Benzoate degradation
     00627  Aminobenzoate degradation
     00364  Fluorobenzoate degradation
     00625  Chloroalkane and chloroalkene degradation
     00361  Chlorocyclohexane and chlorobenzene degradation
     00623  Toluene degradation
     00622  Xylene degradation
     00633  Nitrotoluene degradation
     00642  Ethylbenzene degradation
     00643  Styrene degradation
     00791  Atrazine degradation
     00930  Caprolactam degradation
     00363  Bisphenol degradation
     00621  Dioxin degradation
     00626  Naphthalene degradation
     00624  Polycyclic aromatic hydrocarbon degradation
     00365  Furfural degradation
     00984  Steroid degradation
     00980  Metabolism of xenobiotics by cytochrome P450
     00982  Drug metabolism - cytochrome P450
     00983  Drug metabolism - other enzymes
   Chemical structure transformation maps
     01010  Overview of biosynthetic pathways
     01060  Biosynthesis of plant secondary metabolites
     01061  Biosynthesis of phenylpropanoids
     01062  Biosynthesis of terpenoids and steroids
     01063  Biosynthesis of alkaloids derived from shikimate pathway
     01064  Biosynthesis of alkaloids derived from ornithine, lysine and nicotinic acid
     01065  Biosynthesis of alkaloids derived from histidine and purine
     01066  Biosynthesis of alkaloids derived from terpenoid and polyketide
     01070  Biosynthesis of plant hormones
 
 Genetic Information Processing
   Transcription
     03020  RNA polymerase
     03022  Basal transcription factors
     03040  Spliceosome
   Translation
     03010  Ribosome
     00970  Aminoacyl-tRNA biosynthesis
     03013  Nucleocytoplasmic transport
     03015  mRNA surveillance pathway
     03008  Ribosome biogenesis in eukaryotes
   Folding, sorting and degradation
     03060  Protein export
     04141  Protein processing in endoplasmic reticulum
     04130  SNARE interactions in vesicular transport
     04120  Ubiquitin mediated proteolysis
     04122  Sulfur relay system
     03050  Proteasome
     03018  RNA degradation
   Replication and repair
     03030  DNA replication
     03410  Base excision repair
     03420  Nucleotide excision repair
     03430  Mismatch repair
     03440  Homologous recombination
     03450  Non-homologous end-joining
     03460  Fanconi anemia pathway
   Chromosome
     03082  ATP-dependent chromatin remodeling
     03083  Polycomb repressive complex
   Information processing in viruses
     03230  Viral genome structure
     03240  Viral replication
     03250  Viral life cycle - HIV-1
     03260  Virion - Human immunodeficiency virus
     03271  Virion - Rotavirus
     03262  Virion - Coronavirus
     03261  Virion - Influenza virus
     03263  Virion - Enterovirus
     03264  Virion - Flavivirus and Alphavirus
     03265  Virion - Ebolavirus, Lyssavirus and Morbillivirus
     03273  Virion - Lassa virus and SFTS virus
     03272  Virion - Hepatitis viruses
     03266  Virion - Herpesvirus
     03268  Virion - Orthopoxvirus
     03267  Virion - Adenovirus
     03259  Virion - Bacteriophages T4 and T7
     03258  Virion - Bacteriophage lambda
 
 Environmental Information Processing
   Membrane transport
     02010  ABC transporters
     02060  Phosphotransferase system (PTS)
     03070  Bacterial secretion system
   Signal transduction
     02020  Two-component system
     04010  MAPK signaling pathway
     04013  MAPK signaling pathway - fly
     04016  MAPK signaling pathway - plant
     04011  MAPK signaling pathway - yeast
     04012  ErbB signaling pathway
     04014  Ras signaling pathway
     04015  Rap1 signaling pathway
     04310  Wnt signaling pathway
     04330  Notch signaling pathway
     04340  Hedgehog signaling pathway
     04341  Hedgehog signaling pathway - fly
     04350  TGF-beta signaling pathway
     04390  Hippo signaling pathway
     04391  Hippo signaling pathway - fly
     04392  Hippo signaling pathway - multiple species
     04370  VEGF signaling pathway
     04371  Apelin signaling pathway
     04630  JAK-STAT signaling pathway
     04064  NF-kappa B signaling pathway
     04668  TNF signaling pathway
     04066  HIF-1 signaling pathway
     04068  FoxO signaling pathway
     04020  Calcium signaling pathway
     04070  Phosphatidylinositol signaling system
     04072  Phospholipase D signaling pathway
     04071  Sphingolipid signaling pathway
     04024  cAMP signaling pathway
     04022  cGMP-PKG signaling pathway
     04151  PI3K-Akt signaling pathway
     04152  AMPK signaling pathway
     04150  mTOR signaling pathway
     04075  Plant hormone signal transduction
   Signaling molecules and interaction
     04080  Neuroactive ligand-receptor interaction
     04082  Neuroactive ligand signaling
     04081  Hormone signaling
     04060  Cytokine-cytokine receptor interaction
     04061  Viral protein interaction with cytokine and cytokine receptor
     04512  ECM-receptor interaction
     04514  Cell adhesion molecule (CAM) interaction
     04517  IgSF CAM signaling
     04518  Integrin signaling
 
 Cellular Processes
   Transport and catabolism
     04144  Endocytosis
     04145  Phagosome
     04142  Lysosome
     04146  Peroxisome
     04140  Autophagy - animal
     04138  Autophagy - yeast
     04136  Autophagy - other
     04137  Mitophagy - animal
     04139  Mitophagy - yeast
     04148  Efferocytosis
   Cell growth and death
     04110  Cell cycle
     04111  Cell cycle - yeast
     04112  Cell cycle - Caulobacter
     04113  Meiosis - yeast
     04114  Oocyte meiosis
     04210  Apoptosis
     04214  Apoptosis - fly
     04215  Apoptosis - multiple species
     04216  Ferroptosis
     04217  Necroptosis
     04115  p53 signaling pathway
     04218  Cellular senescence
   Cellular community - eukaryotes
     04510  Focal adhesion
     04520  Adherens junction
     04530  Tight junction
     04540  Gap junction
     04550  Signaling pathways regulating pluripotency of stem cells
   Cellular community - prokaryotes
     02024  Quorum sensing
     05111  Biofilm formation - Vibrio cholerae
     02025  Biofilm formation - Pseudomonas aeruginosa
     02026  Biofilm formation - Escherichia coli
   Cell motility
     02030  Bacterial chemotaxis
     02040  Flagellar assembly
     04814  Motor proteins
     04820  Cytoskeleton in muscle cells
     04810  Regulation of actin cytoskeleton
 
 Organismal Systems
   Immune system
     04640  Hematopoietic cell lineage
     04610  Complement and coagulation cascades
     04611  Platelet activation
     04613  Neutrophil extracellular trap formation
     04620  Toll-like receptor signaling pathway
     04624  Toll and Imd signaling pathway
     04621  NOD-like receptor signaling pathway
     04622  RIG-I-like receptor signaling pathway
     04623  Cytosolic DNA-sensing pathway
     04625  C-type lectin receptor signaling pathway
     04650  Natural killer cell mediated cytotoxicity
     04612  Antigen processing and presentation
     04660  T cell receptor signaling pathway
     04658  Th1 and Th2 cell differentiation
     04659  Th17 cell differentiation
     04657  IL-17 signaling pathway
     04662  B cell receptor signaling pathway
     04664  Fc epsilon RI signaling pathway
     04666  Fc gamma R-mediated phagocytosis
     04670  Leukocyte transendothelial migration
     04672  Intestinal immune network for IgA production
     04062  Chemokine signaling pathway
   Endocrine system
     04911  Insulin secretion
     04910  Insulin signaling pathway
     04922  Glucagon signaling pathway
     04923  Regulation of lipolysis in adipocytes
     04920  Adipocytokine signaling pathway
     03320  PPAR signaling pathway
     04929  GnRH secretion
     04912  GnRH signaling pathway
     04913  Ovarian steroidogenesis
     04915  Estrogen signaling pathway
     04914  Progesterone-mediated oocyte maturation
     04917  Prolactin signaling pathway
     04921  Oxytocin signaling pathway
     04926  Relaxin signaling pathway
     04935  Growth hormone synthesis, secretion and action
     04918  Thyroid hormone synthesis
     04919  Thyroid hormone signaling pathway
     04928  Parathyroid hormone synthesis, secretion and action
     04916  Melanogenesis
     04924  Renin secretion
     04614  Renin-angiotensin system
     04925  Aldosterone synthesis and secretion
     04927  Cortisol synthesis and secretion
   Circulatory system
     04260  Cardiac muscle contraction
     04261  Adrenergic signaling in cardiomyocytes
     04270  Vascular smooth muscle contraction
   Digestive system
     04970  Salivary secretion
     04971  Gastric acid secretion
     04972  Pancreatic secretion
     04976  Bile secretion
     04973  Carbohydrate digestion and absorption
     04974  Protein digestion and absorption
     04975  Fat digestion and absorption
     04979  Cholesterol metabolism
     04977  Vitamin digestion and absorption
     04981  Folate transport and metabolism
     04980  Cobalamin transport and metabolism
     04978  Mineral absorption
   Excretory system
     04962  Vasopressin-regulated water reabsorption
     04960  Aldosterone-regulated sodium reabsorption
     04961  Endocrine and other factor-regulated calcium reabsorption
     04964  Proximal tubule bicarbonate reclamation
     04966  Collecting duct acid secretion
   Nervous system
     04724  Glutamatergic synapse
     04727  GABAergic synapse
     04725  Cholinergic synapse
     04728  Dopaminergic synapse
     04726  Serotonergic synapse
     04720  Long-term potentiation
     04730  Long-term depression
     04723  Retrograde endocannabinoid signaling
     04721  Synaptic vesicle cycle
     04722  Neurotrophin signaling pathway
   Sensory system
     04744  Phototransduction
     04745  Phototransduction - fly
     04740  Olfactory transduction
     04742  Taste transduction
     04750  Inflammatory mediator regulation of TRP channels
   Development and regeneration
     04320  Dorso-ventral axis formation
     04360  Axon guidance
     04361  Axon regeneration
     04380  Osteoclast differentiation
     04382  Cornified envelope formation
   Aging
     04211  Longevity regulating pathway
     04212  Longevity regulating pathway - worm
     04213  Longevity regulating pathway - multiple species
   Environmental adaptation
     04710  Circadian rhythm
     04713  Circadian entrainment
     04711  Circadian rhythm - fly
     04712  Circadian rhythm - plant
     04714  Thermogenesis
     04626  Plant-pathogen interaction
 
 Human Diseases
   Cancer: overview
     05200  Pathways in cancer
     05202  Transcriptional misregulation in cancer
     05206  MicroRNAs in cancer
     05205  Proteoglycans in cancer
     05204  Chemical carcinogenesis - DNA adducts
     05207  Chemical carcinogenesis - receptor activation
     05208  Chemical carcinogenesis - reactive oxygen species
     05203  Viral carcinogenesis
     05230  Central carbon metabolism in cancer
     05231  Choline metabolism in cancer
     05235  PD-L1 expression and PD-1 checkpoint pathway in cancer
   Cancer: specific types
     05210  Colorectal cancer
     05212  Pancreatic cancer
     05225  Hepatocellular carcinoma
     05226  Gastric cancer
     05214  Glioma
     05216  Thyroid cancer
     05221  Acute myeloid leukemia
     05220  Chronic myeloid leukemia
     05217  Basal cell carcinoma
     05218  Melanoma
     05211  Renal cell carcinoma
     05219  Bladder cancer
     05215  Prostate cancer
     05213  Endometrial cancer
     05224  Breast cancer
     05222  Small cell lung cancer
     05223  Non-small cell lung cancer
   Infectious disease: viral
     05166  Human T-cell leukemia virus 1 infection
     05170  Human immunodeficiency virus 1 infection
     05161  Hepatitis B
     05160  Hepatitis C
     05171  Coronavirus disease - COVID-19
     05164  Influenza A
     05162  Measles
     05168  Herpes simplex virus 1 infection
     05163  Human cytomegalovirus infection
     05167  Kaposi sarcoma-associated herpesvirus infection
     05169  Epstein-Barr virus infection
     05165  Human papillomavirus infection
   Infectious disease: bacterial
     05110  Vibrio cholerae infection
     05120  Epithelial cell signaling in Helicobacter pylori infection
     05130  Pathogenic Escherichia coli infection
     05132  Salmonella infection
     05131  Shigellosis
     05135  Yersinia infection
     05133  Pertussis
     05134  Legionellosis
     05150  Staphylococcus aureus infection
     05152  Tuberculosis
     05100  Bacterial invasion of epithelial cells
   Infectious disease: parasitic
     05146  Amoebiasis
     05144  Malaria
     05145  Toxoplasmosis
     05140  Leishmaniasis
     05142  Chagas disease
     05143  African trypanosomiasis
   Immune disease
     05310  Asthma
     05322  Systemic lupus erythematosus
     05323  Rheumatoid arthritis
     05320  Autoimmune thyroid disease
     05321  Inflammatory bowel disease
     05330  Allograft rejection
     05332  Graft-versus-host disease
     05340  Primary immunodeficiency
   Neurodegenerative disease
     05010  Alzheimer disease
     05012  Parkinson disease
     05014  Amyotrophic lateral sclerosis
     05016  Huntington disease
     05017  Spinocerebellar ataxia
     05020  Prion disease
     05022  Pathways of neurodegeneration - multiple diseases
   Substance dependence
     05030  Cocaine addiction
     05031  Amphetamine addiction
     05032  Morphine addiction
     05033  Nicotine addiction
     05034  Alcoholism
   Cardiovascular disease
     05417  Lipid and atherosclerosis
     05418  Fluid shear stress and atherosclerosis
     05410  Hypertrophic cardiomyopathy
     05412  Arrhythmogenic right ventricular cardiomyopathy
     05414  Dilated cardiomyopathy
     05415  Diabetic cardiomyopathy
     05416  Viral myocarditis
   Endocrine and metabolic disease
     04930  Type II diabetes mellitus
     04940  Type I diabetes mellitus
     04950  Maturity onset diabetes of the young
     04936  Alcoholic liver disease
     04932  Non-alcoholic fatty liver disease
     04931  Insulin resistance
     04933  AGE-RAGE signaling pathway in diabetic complications
     04934  Cushing syndrome
   Drug resistance: antimicrobial
     01501  beta-Lactam resistance
     01502  Vancomycin resistance
     01503  Cationic antimicrobial peptide (CAMP) resistance
   Drug resistance: antineoplastic
     01521  EGFR tyrosine kinase inhibitor resistance
     01524  Platinum drug resistance
     01523  Antifolate resistance
     01522  Endocrine resistance
 
 Drug Development
   Chronology: Antiinfectives
     07011  Penicillins
     07012  Cephalosporins - parenteral agents
     07013  Cephalosporins - oral agents
     07021  Aminoglycosides
     07019  Tetracyclines
     07020  Macrolides and ketolides
     07014  Quinolones
     07023  Rifamycins
     07026  Antifungal agents
     07044  Antiviral agents
     07053  Anti-HIV agents
   Chronology: Antineoplastics
     07040  Antineoplastics - alkylating agents
     07041  Antineoplastics - antimetabolic agents
     07042  Antineoplastics - agents from natural products
     07043  Antineoplastics - hormones
     07045  Antineoplastics - protein kinase inhibitors
   Chronology: Nervous system agents
     07032  Hypnotics
     07030  Anxiolytics
     07033  Anticonvulsants
     07015  Local analgesics
     07039  Opioid analgesics
     07028  Antipsychotics
     07029  Antipsychotics - phenothiazines
     07031  Antipsychotics - butyrophenones
     07027  Antidepressants
     07056  Agents for Alzheimer-type dementia
     07057  Antiparkinsonian agents
   Chronology: Other drugs
     07055  Sulfonamide derivatives - overview
     07016  Sulfonamide derivatives - sulfa drugs
     07017  Sulfonamide derivatives - diuretics
     07018  Sulfonamide derivatives - hypoglycemic agents
     07037  Antiarrhythmic drugs
     07038  Antiulcer drugs
     07046  Immunosuppressive agents
     07047  Osteoporosis drugs
     07048  Antimigraines
     07049  Antithrombosis agents
     07050  Antirheumatics - DMARDs and biological agents
     07051  Antidiabetics
     07052  Antidyslipidemic agents
     07054  Antiglaucoma agents
   Target-based classification: G protein-coupled receptors
     07220  Cholinergic and anticholinergic drugs
     07215  alpha-Adrenergic receptor agonists/antagonists
     07214  beta-Adrenergic receptor agonists/antagonists
     07213  Dopamine receptor agonists/antagonists
     07212  Histamine H1 receptor antagonists
     07227  Histamine H2/H3 receptor agonists/antagonists
     07211  Serotonin receptor agonists/antagonists
     07228  Eicosanoid receptor agonists/antagonists
     07224  Opioid receptor agonists/antagonists
     07229  Angiotensin receptor and endothelin receptor antagonists
   Target-based classification: Nuclear receptors
     07225  Glucocorticoid and mineralocorticoid receptor agonists/antagonists
     07226  Progesterone, androgen and estrogen receptor agonists/antagonists
     07223  Retinoic acid receptor (RAR) and retinoid X receptor (RXR) agonists/antagonists
     07222  Peroxisome proliferator-activated receptor (PPAR) agonists
   Target-based classification: Ion channels
     07221  Nicotinic cholinergic receptor antagonists
     07230  GABA-A receptor agonists/antagonists
     07036  Calcium channel blocking drugs
     07231  Sodium channel blocking drugs
     07232  Potassium channel blocking and opening drugs
     07235  N-Methyl-D-aspartic acid (NMDA) receptor antagonists
   Target-based classification: Transporters
     07233  Ion transporter inhibitors
     07234  Neurotransmitter transporter inhibitors
   Target-based classification: Enzymes
     07216  Catecholamine transferase inhibitors
     07219  Cyclooxygenase inhibitors
     07024  HMG-CoA reductase inhibitors
     07217  Renin-angiotensin system inhibitors
     07218  HIV protease inhibitors
   Structure-based classification
     07025  Quinolines
     07034  Eicosanoids
     07035  Prostaglandins
   Skeleton-based classification
     07110  Benzoic acid family
     07112  1,2-Diphenyl substitution family
     07114  Naphthalene family
     07117  Benzodiazepine family

Last updated: December 8, 2025

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