KEGG Modules

Carbohydrate metabolism
Central carbohydrate metabolism
M00001 Glycolysis (Embden-Meyerhof pathway), glucose => pyruvate
M00002 Glycolysis, core module involving three-carbon compounds
M00003 Gluconeogenesis, oxaloacetate => fructose-6P
M00307 Pyruvate oxidation, pyruvate => acetyl-CoA
M00009 Citrate cycle (TCA cycle, Krebs cycle)
M00010 Citrate cycle, first carbon oxidation, oxaloacetate => 2-oxoglutarate
M00011 Citrate cycle, second carbon oxidation, 2-oxoglutarate => oxaloacetate
M00004 Pentose phosphate pathway (Pentose phosphate cycle)
M00006 Pentose phosphate pathway, oxidative phase, glucose-6P => ribulose-5P
M00007 Pentose phosphate pathway, non-oxidative phase, fructose-6P => ribose-5P
M00580 Pentose phosphate pathway, archaea, fructose-6P => ribose-5P
M00005 PRPP biosynthesis, ribose-5P => PRPP

Other carbohydrate metabolism
M00631 Galacturonate degradation, bacteria, galacturonate => pyruvate + glyceraldehyde-3P
M00061 Glucuronate degradation, glucuronate => pyruvate + glyceraldehyde-3P
M00632 Galactose degradation, Leloir pathway, galactose => alpha-D-glucose-1P
M00854 Glycogen biosynthesis, glucose-1P => glycogen/starch
M00855 Glycogen degradation, glycogen => glucose-6P
M00741 Propanoyl-CoA metabolism, propanoyl-CoA => succinyl-CoA

Energy metabolism
Carbon fixation
M00168 CAM (Crassulacean acid metabolism), dark
M00169 CAM (Crassulacean acid metabolism), light
M00579 Phosphate acetyltransferase-acetate kinase pathway, acetyl-CoA => acetate

Methane metabolism
M00345 Formaldehyde assimilation, ribulose monophosphate pathway

Sulfur metabolism
M00176 Assimilatory sulfate reduction, sulfate => H2S

ATP synthesis
M00144 NADH:quinone oxidoreductase, prokaryotes
M00157 F-type ATPase, prokaryotes and chloroplasts

Lipid metabolism
Fatty acid metabolism
M00082 Fatty acid biosynthesis, initiation
M00083 Fatty acid biosynthesis, elongation
M00086 beta-Oxidation, acyl-CoA synthesis

Lipid metabolism
M00098 Acylglycerol degradation
M00093 Phosphatidylethanolamine (PE) biosynthesis, PA => PS => PE

Nucleotide metabolism
Purine metabolism
M00048 De novo purine biosynthesis, PRPP + glutamine => IMP
M00049 Adenine ribonucleotide biosynthesis, IMP => ADP,ATP
M00050 Guanine ribonucleotide biosynthesis, IMP => GDP,GTP
M00053 Deoxyribonucleotide biosynthesis, ADP/GDP/CDP/UDP => dATP/dGTP/dCTP/dUTP

Pyrimidine metabolism
M00051 De novo pyrimidine biosynthesis, glutamine (+ PRPP) => UMP
M00052 Pyrimidine ribonucleotide biosynthesis, UMP => UDP/UTP,CDP/CTP
M00938 Pyrimidine deoxyribonucleotide biosynthesis, UDP => dTTP

Amino acid metabolism
Serine and threonine metabolism
M00020 Serine biosynthesis, glycerate-3P => serine
M00018 Threonine biosynthesis, aspartate => homoserine => threonine
M00621 Glycine cleavage system

Cysteine and methionine metabolism
M00021 Cysteine biosynthesis, serine => cysteine
M00338 Cysteine biosynthesis, homocysteine + serine => cysteine
M00017 Methionine biosynthesis, aspartate => homoserine => methionine
M00035 Methionine degradation

Branched-chain amino acid metabolism
M00019 Valine/isoleucine biosynthesis, pyruvate => valine / 2-oxobutanoate => isoleucine
M00535 Isoleucine biosynthesis, pyruvate => 2-oxobutanoate
M00570 Isoleucine biosynthesis, threonine => 2-oxobutanoate => isoleucine
M00432 Leucine biosynthesis, 2-oxoisovalerate => 2-oxoisocaproate

Lysine metabolism
M00016 Lysine biosynthesis, succinyl-DAP pathway, aspartate => lysine
M00526 Lysine biosynthesis, DAP dehydrogenase pathway, aspartate => lysine
M00527 Lysine biosynthesis, DAP aminotransferase pathway, aspartate => lysine

Arginine and proline metabolism
M00028 Ornithine biosynthesis, glutamate => ornithine
M00844 Arginine biosynthesis, ornithine => arginine
M00015 Proline biosynthesis, glutamate => proline
M00970 Proline degradation, proline => glutamate

Polyamine biosynthesis
M00133 Polyamine biosynthesis, arginine => agmatine => putrescine => spermidine
M00134 Polyamine biosynthesis, arginine => ornithine => putrescine

Histidine metabolism
M00026 Histidine biosynthesis, PRPP => histidine
M00045 Histidine degradation, histidine => N-formiminoglutamate => glutamate

Aromatic amino acid metabolism
M00022 Shikimate pathway, phosphoenolpyruvate + erythrose-4P => chorismate
M00023 Tryptophan biosynthesis, chorismate => tryptophan
M00024 Phenylalanine biosynthesis, chorismate => phenylpyruvate => phenylalanine
M00025 Tyrosine biosynthesis, chorismate => HPP => tyrosine
M00040 Tyrosine biosynthesis, chorismate => arogenate => tyrosine

Other amino acid metabolism
M00027 GABA (gamma-Aminobutyrate) shunt
M00118 Glutathione biosynthesis, glutamate => glutathione

Glycan metabolism
Nucleotide sugar biosynthesis
M00909 UDP-GlcNAc biosynthesis, prokaryotes, Fru-6P => UDP-GlcNAc
M00995 UDP-MurNAc biosynthesis, Fru-6P => UDP-MurNAc
M00549 UDP-Glc biosynthesis, Glc => UDP-Glc
M01004 UDP-Galf biosynthesis, UDP-Glc => UDP-Galf
M00997 UDP-Xyl/L-Ara biosynthesis, UDP-Glc => UDP-Xyl => UDP-L-Ala
M00999 UDP-GlcA/GalA biosynthesis, UDP-Glc => UDP-GlcA => UDP-GalA
M00554 UDP-Gal biosynthesis, Gal => UDP-Gal
M01000 GDP-Man biosynthesis, Fru-6P => GDP-Man
M01015 GDP-Man biosynthesis, Man => GDP-Man
M01001 GDP-L-Fuc biosynthesis, L-Fuc => GDP-L-Fuc
M01036 UDP-GalNAcA biosynthesis, UDP-GlcNAc => UDP-GalNAcA
M00923 UDP-L-FucNAc biosynthesis, UDP-GlcNAc => UDP-L-FucNAc
M01011 CMP-Leg5Ac7Ac biosynthesis, UDP-BacNAc4NAc => CMP-Leg5Ac7Ac
M00063 CMP-KDO biosynthesis, ribulose-5P => CMP-KDO
M01014 UDP-ManNAcA biosynthesis, UDP-GlcNAc => UDP-ManNAcA
M00793 dTDP-L-Rha biosynthesis, Glc-1P => dTDP-L-Rha
M01006 GDP-D-Rha4N biosynthesis, Fru-6P => GDP-D-Rha4N
M01016 GDP-L-Fuc biosynthesis, GDP-Man => GDP-L-Fuc
M01018 GDP-D-Rha biosynthesis, GDP-Man => GDP-D-Rha

Metabolism of cofactors and vitamins
Cofactor and vitamin metabolism
M00127 Thiamine biosynthesis, prokaryotes, AIR (+ DXP/tyrosine) => TMP/TPP
M00899 Thiamine salvage pathway, HMP/HET => TMP
M00125 Riboflavin biosynthesis, plants and bacteria, GTP => riboflavin/FMN/FAD
M00916 Pyridoxal phosphate biosynthesis, R5P + glyceraldehyde-3P + glutamine => pyridoxal-P
M00115 NAD biosynthesis, aspartate => quinolinate => NAD
M00119 Pantothenate biosynthesis, valine/L-aspartate => pantothenate
M00120 Coenzyme A biosynthesis, pantothenate => CoA
M00572 Pimeloyl-ACP biosynthesis, BioC-BioH pathway, malonyl-ACP => pimeloyl-ACP
M00123 Biotin biosynthesis, pimeloyl-ACP/CoA => biotin
M00577 Biotin biosynthesis, BioW pathway, pimelate => pimeloyl-CoA => biotin
M00881 Lipoic acid biosynthesis, plants and bacteria, octanoyl-ACP => dihydrolipoyl-E2/H
M00126 Tetrahydrofolate biosynthesis, GTP => THF
M00988 PreQ1 biosynthesis, GTP => 7-Aminomethyl-7-deazaguanine
M00140 C1-unit interconversion, prokaryotes
M00924 Cobalamin biosynthesis, anaerobic, uroporphyrinogen III => sirohydrochlorin => cobyri..
M00122 Cobalamin biosynthesis, cobyrinate a,c-diamide => cobalamin
M00930 Menaquinone biosynthesis, futalosine pathway

Gene set
Drug resistance
M00627 beta-Lactam resistance, Bla system
M00652 Vancomycin resistance, D-Ala-D-Ser type

Module set
Metabolic capacity
M00616 Sulfate-sulfur assimilation