KEGG Modules
Pathway modules
Carbohydrate metabolism
Central carbohydrate metabolism
M00001 Glycolysis (Embden-Meyerhof pathway), glucose => pyruvate
M00002 Glycolysis, core module involving three-carbon compounds
M00003 Gluconeogenesis, oxaloacetate => fructose-6P
M00307 Pyruvate oxidation, pyruvate => acetyl-CoA
M00009 Citrate cycle (TCA cycle, Krebs cycle)
M00010 Citrate cycle, first carbon oxidation, oxaloacetate => 2-oxoglutarate
M00011 Citrate cycle, second carbon oxidation, 2-oxoglutarate => oxaloacetate
M00004 Pentose phosphate pathway (Pentose phosphate cycle)
M00006 Pentose phosphate pathway, oxidative phase, glucose-6P => ribulose-5P
M00007 Pentose phosphate pathway, non-oxidative phase, fructose-6P => ribose-5P
M00580 Pentose phosphate pathway, archaea, fructose-6P => ribose-5P
M00005 PRPP biosynthesis, ribose-5P => PRPP
Other carbohydrate metabolism
M00855 Glycogen degradation, glycogen => glucose-6P
Energy metabolism
Carbon fixation
M00579 Phosphate acetyltransferase-acetate kinase pathway, acetyl-CoA => acetate
Methane metabolism
M00345 Formaldehyde assimilation, ribulose monophosphate pathway
ATP synthesis
M00144 NADH:quinone oxidoreductase, prokaryotes
M00416 Cytochrome aa3-600 menaquinol oxidase
M00157 F-type ATPase, prokaryotes and chloroplasts
Lipid metabolism
Fatty acid metabolism
M00082 Fatty acid biosynthesis, initiation
M00083 Fatty acid biosynthesis, elongation
M00086 beta-Oxidation, acyl-CoA synthesis
Nucleotide metabolism
Purine metabolism
M00048 De novo purine biosynthesis, PRPP + glutamine => IMP
M00049 Adenine ribonucleotide biosynthesis, IMP => ADP,ATP
M00050 Guanine ribonucleotide biosynthesis, IMP => GDP,GTP
M00053 Deoxyribonucleotide biosynthesis, ADP/GDP/CDP/UDP => dATP/dGTP/dCTP/dUTP
Pyrimidine metabolism
M00051 De novo pyrimidine biosynthesis, glutamine (+ PRPP) => UMP
M00052 Pyrimidine ribonucleotide biosynthesis, UMP => UDP/UTP,CDP/CTP
M00938 Pyrimidine deoxyribonucleotide biosynthesis, UDP => dTTP
Amino acid metabolism
Serine and threonine metabolism
M00020 Serine biosynthesis, glycerate-3P => serine
M00018 Threonine biosynthesis, aspartate => homoserine => threonine
M00621 Glycine cleavage system
M00555 Betaine biosynthesis, choline => betaine
Cysteine and methionine metabolism
M00021 Cysteine biosynthesis, serine => cysteine
M00017 Methionine biosynthesis, aspartate => homoserine => methionine
Branched-chain amino acid metabolism
M00432 Leucine biosynthesis, 2-oxoisovalerate => 2-oxoisocaproate
Lysine metabolism
M00016 Lysine biosynthesis, succinyl-DAP pathway, aspartate => lysine
Arginine and proline metabolism
M00028 Ornithine biosynthesis, glutamate => ornithine
M00844 Arginine biosynthesis, ornithine => arginine
M00015 Proline biosynthesis, glutamate => proline
M00970 Proline degradation, proline => glutamate
M00972 Proline metabolism
Polyamine biosynthesis
M00134 Polyamine biosynthesis, arginine => ornithine => putrescine
Histidine metabolism
M00026 Histidine biosynthesis, PRPP => histidine
M00045 Histidine degradation, histidine => N-formiminoglutamate => glutamate
Aromatic amino acid metabolism
M00022 Shikimate pathway, phosphoenolpyruvate + erythrose-4P => chorismate
M00023 Tryptophan biosynthesis, chorismate => tryptophan
Other amino acid metabolism
M00949 Staphylopine biosynthesis, L-histidine => staphylopine
Glycan metabolism
Nucleotide sugar biosynthesis
M00909 UDP-GlcNAc biosynthesis, prokaryotes, Fru-6P => UDP-GlcNAc
M00995 UDP-MurNAc biosynthesis, Fru-6P => UDP-MurNAc
M00549 UDP-Glc biosynthesis, Glc => UDP-Glc
M01000 GDP-Man biosynthesis, Fru-6P => GDP-Man
M01015 GDP-Man biosynthesis, Man => GDP-Man
M00793 dTDP-L-Rha biosynthesis, Glc-1P => dTDP-L-Rha
Metabolism of cofactors and vitamins
Cofactor and vitamin metabolism
M00899 Thiamine salvage pathway, HMP/HET => TMP
M00125 Riboflavin biosynthesis, plants and bacteria, GTP => riboflavin/FMN/FAD
M00916 Pyridoxal phosphate biosynthesis, R5P + glyceraldehyde-3P + glutamine => pyridoxal-P
M00115 NAD biosynthesis, aspartate => quinolinate => NAD
M00119 Pantothenate biosynthesis, valine/L-aspartate => pantothenate
M00120 Coenzyme A biosynthesis, pantothenate => CoA
M00123 Biotin biosynthesis, pimeloyl-ACP/CoA => biotin
M00577 Biotin biosynthesis, BioW pathway, pimelate => pimeloyl-CoA => biotin
M00881 Lipoic acid biosynthesis, plants and bacteria, octanoyl-ACP => dihydrolipoyl-E2/H
M00882 Lipoic acid biosynthesis, eukaryotes, octanoyl-ACP => dihydrolipoyl-H
M00883 Lipoic acid biosynthesis, animals and bacteria, octanoyl-ACP => dihydrolipoyl-H => di..
M00126 Tetrahydrofolate biosynthesis, GTP => THF
M00880 Molybdenum cofactor biosynthesis, GTP => molybdenum cofactor
M00988 PreQ1 biosynthesis, GTP => 7-Aminomethyl-7-deazaguanine
M00140 C1-unit interconversion, prokaryotes
M00141 C1-unit interconversion, eukaryotes
M00926 Heme biosynthesis, bacteria, glutamyl-tRNA => coproporphyrin III => heme
M00116 Menaquinone biosynthesis, chorismate (+ polyprenyl-PP) => menaquinol
Biosynthesis of terpenoids and polyketides
Terpenoid backbone biosynthesis
M00096 C5 isoprenoid biosynthesis, non-mevalonate pathway
M00364 C10-C20 isoprenoid biosynthesis, bacteria
M00365 C10-C20 isoprenoid biosynthesis, archaea
Signature modules
Gene set
Drug resistance
M00627 beta-Lactam resistance, Bla system
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