| Entry | T08175 |
| Org code | cng |
| Name | Cryptococcus neoformans var. grubii H99 |
| Annotation | yes |
| Taxonomy | TAX:235443 |
| Lineage | Eukaryota; Fungi; Basidiomycota; Tremellomycetes; Tremellales; Cryptococcaceae; Cryptococcus; Cryptococcus neoformans |
| Org group | Fungi; Basidiomycetes; Tremellomycetes |
| Brite | KEGG organisms [BR:br08601]
KEGG organisms in the NCBI taxonomy [BR:br08610]
KEGG organisms in taxonomic ranks [BR:br08611]
KEGG organisms: fungi [BR:br08614] |
| Data source | RefSeq (Assembly: GCF_000149245.1 Chromosome) |
| Keywords | Human pathogen |
| Disease | H00364 Cryptococcosis |
| Comment | Host: Homo sapiens [GN:hsa] [TAX:9606]
Pathogenic basidiomycetous yeast.
Major human pathogen responsible for deadly meningoencephalitis in immunocompromised patients.
Originally isolated in 1978 at Duke University Medical Center. |
| Chromosome | 1 (RS: NC_026745)
2 (RS: NC_026746)
3 (RS: NC_026747)
4 (RS: NC_026748)
5 (RS: NC_026749)
6 (RS: NC_026750)
7 (RS: NC_026751)
8 (RS: NC_026752)
9 (RS: NC_026753)
10 (RS: NC_026754)
11 (RS: NC_026755)
12 (RS: NC_026756)
13 (RS: NC_026757)
14 (RS: NC_026758)
MT; Circular (RS: NC_018792) |
| Statistics | Number of protein genes: 6975
Number of RNA genes: 1215 |
| Created | 2022 |
| Reference | PMID: 24743168 |
| Authors | Janbon G, Ormerod KL, Paulet D, Byrnes EJ 3rd, Yadav V, Chatterjee G, Mullapudi N, Hon CC, Billmyre RB, Brunel F, et al. |
| Title | Analysis of the genome and transcriptome of Cryptococcus neoformans var. grubii reveals complex RNA expression and microevolution leading to virulence attenuation. |
| Journal | PLoS Genet 10:e1004261 (2014)
DOI: 10.1371/journal.pgen.1004261 |