[ Network menu | Network entry | Help ]

ENTRY	nt06015
Name	N-Glycan biosynthesis
Category	Pathway view; Glycan/glycoprotein metabolism
Pathway	hsa00510 N-Glycan biosynthesis hsa00520 Amino sugar and nucleotide sugar metabolism
Module	hsa_M00055 N-glycan precursor biosynthesis hsa_M00073 N-glycan precursor trimming hsa_M00075 N-glycan biosynthesis, complex type
Disease	H00118 Congenital disorders of glycosylation type I (CDG-I) H00119 Congenital disorders of glycosylation type II (CDG-II)
Display	drug-target relation   disease type

N00675    F-PP − (DHDDS+NUS1) ⇉ SRD5A3 ⇉ DOLK → P-Dol     CDG-Ibb     DHDDS*     CDG-Iaa     NUS1*     CDG-Iq         SRD5A3*     CDG-Im             DOLK*   N00653    P-Dol − ALG7 ⇉ (ALG13+ALG14) ⇉ ALG1 ⇉ ALG2 ⇉ ALG11 → G00006     CDG-Ij     ALG7*     CDG-Is         ALG13*     CDG-Ik             ALG1*     CDG-Ii                 ALG2*     CDG-Ip                     ALG11*   N00667    Glc-6P − GPI ⇉ MPI ⇉ PMM1/2 ⇉ GMPP ⇉ DPM1/2/3 → Man-P-Dol     CDG-Ib         MPI*     CDG-Ia             PMM2*     CDG-Ie                     DPM1*     CDG-Iu                     DPM2*     CDG-Io                     DPM3*   N00830    G00006 − RFT1 → G00006(ER)     CDG-In     RFT1*   N00680    G00006+Man-P-Dol − ALG3 ⇉ ALG9 ⇉ ALG12 ⇉ ALG9 → G00007     CDG-Id     ALG3*     CDG-IL         ALG9*     CDG-Ig             ALG12*   N00673    Glc-6P − PGM1/2 ⇉ UGP2 → UDP-Glc N00682                UDP-Glc+P-Dol − ALG5 → Glc-P-Dol     CDG-It     PGM1*   N00681    G00007+Glc-P-Dol − ALG6 ⇉ ALG8 ⇉ ALG10 ⇉ (STT+OST) → G00009     CDG-Ic     ALG6*     CDG-Ih         ALG8*     CDG-Iw                 STT3A*     CDG-Ix                 STT3B*     CDG-Ir                 DDOST*   N00820    G00009 − MOGS ⇉ GANAB ⇉ MAN1 ⇉ MGAT1 ⇉ MAN2 ⇉ MGAT2 ⇉ FUT8 ⇉ B4GALT ⇉ ST6GAL → G00018     CDG-IIb     MOGS*     CDG-IIa                         MGAT2*     CDG-IId                                 B4GALT1*   N00824    GDP-Fuc − SLC35C1 → GDP-Fuc(Golgi)     CDG-IIc     SLC35C1*   N00826    UDP-Gal − SLC35A2 → UDP-Gal(Golgi)     CDG-IIm     SLC35A2*   N00828    CMP-Neu5Ac − SLC35A1 → CMP-Neu5Ac(Golgi)     CDG-IIf     SLC35A1*

		Disease name	Disease category
CDG-Ibb	H00118	Congenital disorders of glycosylation type I	Inherited metabolic disorder
CDG-Iaa	H00118	Congenital disorders of glycosylation type I	Inherited metabolic disorder
CDG-Iq	H00118	Congenital disorders of glycosylation type I	Inherited metabolic disorder
CDG-Im	H00118	Congenital disorders of glycosylation type I	Inherited metabolic disorder
CDG-Ij	H00118	Congenital disorders of glycosylation type I	Inherited metabolic disorder
CDG-Is	H00118	Congenital disorders of glycosylation type I	Inherited metabolic disorder
CDG-Ik	H00118	Congenital disorders of glycosylation type I	Inherited metabolic disorder
CDG-Ii	H00118	Congenital disorders of glycosylation type I	Inherited metabolic disorder
CDG-Ip	H00118	Congenital disorders of glycosylation type I	Inherited metabolic disorder
CDG-Ib	H00118	Congenital disorders of glycosylation type I	Inherited metabolic disorder
CDG-Ia	H00118	Congenital disorders of glycosylation type I	Inherited metabolic disorder
CDG-Ie	H00118	Congenital disorders of glycosylation type I	Inherited metabolic disorder
CDG-Iu	H00118	Congenital disorders of glycosylation type I	Inherited metabolic disorder
CDG-Io	H00118	Congenital disorders of glycosylation type I	Inherited metabolic disorder
CDG-In	H00118	Congenital disorders of glycosylation type I	Inherited metabolic disorder
CDG-Id	H00118	Congenital disorders of glycosylation type I	Inherited metabolic disorder
CDG-IL	H00118	Congenital disorders of glycosylation type I	Inherited metabolic disorder
CDG-Ig	H00118	Congenital disorders of glycosylation type I	Inherited metabolic disorder
CDG-It	H00118	Congenital disorders of glycosylation type I	Inherited metabolic disorder
CDG-Ic	H00118	Congenital disorders of glycosylation type I	Inherited metabolic disorder
CDG-Ih	H00118	Congenital disorders of glycosylation type I	Inherited metabolic disorder
CDG-Iw	H00118	Congenital disorders of glycosylation type I	Inherited metabolic disorder
CDG-Ix	H00118	Congenital disorders of glycosylation type I	Inherited metabolic disorder
CDG-Ir	H00118	Congenital disorders of glycosylation type I	Inherited metabolic disorder
CDG-IIb	H00119	Congenital disorders of glycosylation type II	Inherited metabolic disorder
CDG-IIa	H00119	Congenital disorders of glycosylation type II	Inherited metabolic disorder
CDG-IId	H00119	Congenital disorders of glycosylation type II	Inherited metabolic disorder
CDG-IIc	H00119	Congenital disorders of glycosylation type II	Inherited metabolic disorder
CDG-IIm	H00119	Congenital disorders of glycosylation type II	Inherited metabolic disorder
CDG-IIf	H00119	Congenital disorders of glycosylation type II	Inherited metabolic disorder