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ENTRY	nt06015
Name	N-Glycan biosynthesis
Category	Pathway view; Glycan/glycoprotein metabolism
Pathway	hsa00510 N-Glycan biosynthesis hsa00520 Amino sugar and nucleotide sugar metabolism
Module	hsa_M00055 N-glycan precursor biosynthesis hsa_M00072 N-glycosylation by oligosaccharyltransferase hsa_M00073 N-glycan precursor trimming hsa_M00075 N-glycan biosynthesis, complex type
Disease	H00118 Congenital disorders of glycosylation type I (CDG-I) H00119 Congenital disorders of glycosylation type II (CDG-II)
Display	drug-target relation   disease type

N00675    F-PP − (DHDDS+NUS1) ⇉ DHRSX ⇉ SRD5A3 ⇉ DOLK → P-Dol     CDG1BB     DHDDS*     CDG1AA     NUS1*     CDG1DD         DHRSX*     CDG1Q             SRD5A3*     CDG1M                 DOLK*   N00653    P-Dol − ALG7 ⇉ (ALG13+ALG14) ⇉ ALG1 ⇉ ALG2 ⇉ ALG11 → G00006     CDG1J     ALG7*     CDG1S         ALG13*     CDG1K             ALG1*     CDG1I                 ALG2*     CDG1P                     ALG11*   N00667    Glc-6P − GPI ⇉ MPI ⇉ PMM1/2 ⇉ GMPP ⇉ DPM1/2/3 → Man-P-Dol     CDG1B         MPI*     CDG1A             PMM2*     CDG1E                     DPM1*     CDG1U                     DPM2*     CDG1O                     DPM3*   N00830    G00006 − RFT1 → G00006(ER)     CDG1N     RFT1*   N00680    G00006+Man-P-Dol − ALG3 ⇉ ALG9 ⇉ ALG12 ⇉ ALG9 → G00007     CDG1D     ALG3*     CDG1L         ALG9*     CDG1G             ALG12*   N00673    Glc-6P − PGM1/2 ⇉ UGP2 → UDP-Glc N00682                UDP-Glc+P-Dol − ALG5 → Glc-P-Dol     CDG1T     PGM1*   N00681    G00007+Glc-P-Dol − ALG6 ⇉ ALG8 ⇉ ALG10 ⇉ (STT+OST) → G00009     CDG1C     ALG6*     CDG1H         ALG8*     CDG1WAR                 STT3A*     CDG1X                 STT3B*     CDG1R                 DDOST*     CDG1CC                 MAGT1*   N00820    G00009 − MOGS ⇉ GANAB ⇉ MAN1 ⇉ MGAT1 ⇉ MAN2 ⇉ MGAT2 ⇉ FUT8 ⇉ B4GALT ⇉ ST6GAL → G00018     CDG2B     MOGS*     CDG2A                         MGAT2*     CDG2D                                 B4GALT1*   N00824    GDP-Fuc − SLC35C1 → GDP-Fuc(Golgi)     CDG2C     SLC35C1*   N00826    UDP-Gal − SLC35A2 → UDP-Gal(Golgi)     CDG2M     SLC35A2*   N00828    CMP-Neu5Ac − SLC35A1 → CMP-Neu5Ac(Golgi)     CDG2F     SLC35A1*

		Disease name	Disease category
CDG1BB	H00118	Congenital disorders of glycosylation type I	Inherited metabolic disorder
CDG1AA	H00118	Congenital disorders of glycosylation type I	Inherited metabolic disorder
CDG1DD	H00118	Congenital disorders of glycosylation type I	Inherited metabolic disorder
CDG1Q	H00118	Congenital disorders of glycosylation type I	Inherited metabolic disorder
CDG1M	H00118	Congenital disorders of glycosylation type I	Inherited metabolic disorder
CDG1J	H00118	Congenital disorders of glycosylation type I	Inherited metabolic disorder
CDG1S	H00118	Congenital disorders of glycosylation type I	Inherited metabolic disorder
CDG1K	H00118	Congenital disorders of glycosylation type I	Inherited metabolic disorder
CDG1I	H00118	Congenital disorders of glycosylation type I	Inherited metabolic disorder
CDG1P	H00118	Congenital disorders of glycosylation type I	Inherited metabolic disorder
CDG1B	H00118	Congenital disorders of glycosylation type I	Inherited metabolic disorder
CDG1A	H00118	Congenital disorders of glycosylation type I	Inherited metabolic disorder
CDG1E	H00118	Congenital disorders of glycosylation type I	Inherited metabolic disorder
CDG1U	H00118	Congenital disorders of glycosylation type I	Inherited metabolic disorder
CDG1O	H00118	Congenital disorders of glycosylation type I	Inherited metabolic disorder
CDG1N	H00118	Congenital disorders of glycosylation type I	Inherited metabolic disorder
CDG1D	H00118	Congenital disorders of glycosylation type I	Inherited metabolic disorder
CDG1L	H00118	Congenital disorders of glycosylation type I	Inherited metabolic disorder
CDG1G	H00118	Congenital disorders of glycosylation type I	Inherited metabolic disorder
CDG1T	H00118	Congenital disorders of glycosylation type I	Inherited metabolic disorder
CDG1C	H00118	Congenital disorders of glycosylation type I	Inherited metabolic disorder
CDG1H	H00118	Congenital disorders of glycosylation type I	Inherited metabolic disorder
CDG1WAR	H00118	Congenital disorders of glycosylation type I	Inherited metabolic disorder
CDG1X	H00118	Congenital disorders of glycosylation type I	Inherited metabolic disorder
CDG1R	H00118	Congenital disorders of glycosylation type I	Inherited metabolic disorder
CDG1CC	H00118	Congenital disorders of glycosylation type I	Inherited metabolic disorder
CDG2B	H00119	Congenital disorders of glycosylation type II	Inherited metabolic disorder
CDG2A	H00119	Congenital disorders of glycosylation type II	Inherited metabolic disorder
CDG2D	H00119	Congenital disorders of glycosylation type II	Inherited metabolic disorder
CDG2C	H00119	Congenital disorders of glycosylation type II	Inherited metabolic disorder
CDG2M	H00119	Congenital disorders of glycosylation type II	Inherited metabolic disorder
CDG2F	H00119	Congenital disorders of glycosylation type II	Inherited metabolic disorder