KEGG    Network variation - N-Glycan biosynthesis
[ Network menu | Network entry | Help ]
ENTRYnt06015
NameN-Glycan biosynthesis
CategoryPathway view; Glycan/glycoprotein metabolism
Pathwayhsa00510 N-Glycan biosynthesis
hsa00520 Amino sugar and nucleotide sugar metabolism
Modulehsa_M00055 N-glycan precursor biosynthesis
hsa_M00072 N-glycosylation by oligosaccharyltransferase
hsa_M00073 N-glycan precursor trimming
hsa_M00075 N-glycan biosynthesis, complex type
DiseaseH00118 Congenital disorders of glycosylation type I (CDG-I)
H00119 Congenital disorders of glycosylation type II (CDG-II)
Display drug-target relation   disease type
N00675    F-PP−(DHDDS+NUS1)⇉DHRSX⇉SRD5A3⇉DOLK→P-Dol
    CDG1BB   DHDDS*
    CDG1AA   NUS1*
    CDG1DD     DHRSX*
    CDG1Q       SRD5A3*
    CDG1M         DOLK*
 
N00653    P-Dol−ALG7⇉(ALG13+ALG14)⇉ALG1⇉ALG2⇉ALG11→G00006
    CDG1J   ALG7*
    CDG1S     ALG13*
    CDG1K       ALG1*
    CDG1I         ALG2*
    CDG1P           ALG11*
 
N00667    Glc-6P−GPI⇉MPI⇉PMM1/2⇉GMPP⇉DPM1/2/3→Man-P-Dol
    CDG1B     MPI*
    CDG1A       PMM2*
    CDG1E           DPM1*
    CDG1U           DPM2*
    CDG1O           DPM3*
 
N00830    G00006−RFT1→G00006(ER)
    CDG1N   RFT1*
 
N00680    G00006+Man-P-Dol−ALG3⇉ALG9⇉ALG12⇉ALG9→G00007
    CDG1D   ALG3*
    CDG1L     ALG9*
    CDG1G       ALG12*
 
N00673    Glc-6P−PGM1/2⇉UGP2→UDP-Glc
N00682          UDP-Glc+P-Dol−ALG5→Glc-P-Dol
    CDG1T   PGM1*
 
N00681    G00007+Glc-P-Dol−ALG6⇉ALG8⇉ALG10⇉(STT+OST)→G00009
    CDG1C   ALG6*
    CDG1H     ALG8*
    CDG1WAR         STT3A*
    CDG1X         STT3B*
    CDG1R         DDOST*
    CDG1CC         MAGT1*
 
N00820    G00009−MOGS⇉GANAB⇉MAN1⇉MGAT1⇉MAN2⇉MGAT2⇉FUT8⇉B4GALT⇉ST6GAL→G00018
    CDG2B   MOGS*
    CDG2A             MGAT2*
    CDG2D                 B4GALT1*
 
N00824    GDP-Fuc−SLC35C1→GDP-Fuc(Golgi)
    CDG2C   SLC35C1*
 
N00826    UDP-Gal−SLC35A2→UDP-Gal(Golgi)
    CDG2M   SLC35A2*
 
N00828    CMP-Neu5Ac−SLC35A1→CMP-Neu5Ac(Golgi)
    CDG2F   SLC35A1*

Disease nameDisease category
CDG1BBH00118Congenital disorders of glycosylation type IInherited metabolic disorder
CDG1AAH00118Congenital disorders of glycosylation type IInherited metabolic disorder
CDG1DDH00118Congenital disorders of glycosylation type IInherited metabolic disorder
CDG1QH00118Congenital disorders of glycosylation type IInherited metabolic disorder
CDG1MH00118Congenital disorders of glycosylation type IInherited metabolic disorder
CDG1JH00118Congenital disorders of glycosylation type IInherited metabolic disorder
CDG1SH00118Congenital disorders of glycosylation type IInherited metabolic disorder
CDG1KH00118Congenital disorders of glycosylation type IInherited metabolic disorder
CDG1IH00118Congenital disorders of glycosylation type IInherited metabolic disorder
CDG1PH00118Congenital disorders of glycosylation type IInherited metabolic disorder
CDG1BH00118Congenital disorders of glycosylation type IInherited metabolic disorder
CDG1AH00118Congenital disorders of glycosylation type IInherited metabolic disorder
CDG1EH00118Congenital disorders of glycosylation type IInherited metabolic disorder
CDG1UH00118Congenital disorders of glycosylation type IInherited metabolic disorder
CDG1OH00118Congenital disorders of glycosylation type IInherited metabolic disorder
CDG1NH00118Congenital disorders of glycosylation type IInherited metabolic disorder
CDG1DH00118Congenital disorders of glycosylation type IInherited metabolic disorder
CDG1LH00118Congenital disorders of glycosylation type IInherited metabolic disorder
CDG1GH00118Congenital disorders of glycosylation type IInherited metabolic disorder
CDG1TH00118Congenital disorders of glycosylation type IInherited metabolic disorder
CDG1CH00118Congenital disorders of glycosylation type IInherited metabolic disorder
CDG1HH00118Congenital disorders of glycosylation type IInherited metabolic disorder
CDG1WARH00118Congenital disorders of glycosylation type IInherited metabolic disorder
CDG1XH00118Congenital disorders of glycosylation type IInherited metabolic disorder
CDG1RH00118Congenital disorders of glycosylation type IInherited metabolic disorder
CDG1CC H00118Congenital disorders of glycosylation type IInherited metabolic disorder
CDG2BH00119Congenital disorders of glycosylation type IIInherited metabolic disorder
CDG2AH00119Congenital disorders of glycosylation type IIInherited metabolic disorder
CDG2DH00119Congenital disorders of glycosylation type IIInherited metabolic disorder
CDG2CH00119Congenital disorders of glycosylation type IIInherited metabolic disorder
CDG2MH00119Congenital disorders of glycosylation type IIInherited metabolic disorder
CDG2FH00119Congenital disorders of glycosylation type IIInherited metabolic disorder