KEGG    Network variation - N-Glycan biosynthesis
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ENTRYnt06015
NameN-Glycan biosynthesis
CategoryPathway view; Glycan/glycoprotein metabolism
Pathwayhsa00510 N-Glycan biosynthesis
hsa00520 Amino sugar and nucleotide sugar metabolism
Modulehsa_M00055 N-glycan precursor biosynthesis
hsa_M00072 N-glycosylation by oligosaccharyltransferase
hsa_M00073 N-glycan precursor trimming
hsa_M00075 N-glycan biosynthesis, complex type
DiseaseH00118 Congenital disorders of glycosylation type I (CDG-I)
H00119 Congenital disorders of glycosylation type II (CDG-II)
Display drug-target relation   disease type
N00675    F-PP−(DHDDS+NUS1)⇉DHRSX⇉SRD5A3⇉DOLK→P-Dol
      DHDDS*
      NUS1*
        DHRSX*
          SRD5A3*
            DOLK*
 
N00653    P-Dol−ALG7⇉(ALG13+ALG14)⇉ALG1⇉ALG2⇉ALG11→G00006
      ALG7*
        ALG13*
          ALG1*
            ALG2*
              ALG11*
 
N00667    Glc-6P−GPI⇉MPI⇉PMM1/2⇉GMPP⇉DPM1/2/3→Man-P-Dol
        MPI*
          PMM2*
              DPM1*
              DPM2*
              DPM3*
 
N00830    G00006−RFT1→G00006(ER)
      RFT1*
 
N00680    G00006+Man-P-Dol−ALG3⇉ALG9⇉ALG12⇉ALG9→G00007
      ALG3*
        ALG9*
          ALG12*
 
N00673    Glc-6P−PGM1/2⇉UGP2→UDP-Glc
N00682          UDP-Glc+P-Dol−ALG5→Glc-P-Dol
      PGM1*
 
N00681    G00007+Glc-P-Dol−ALG6⇉ALG8⇉ALG10⇉(STT+OST)→G00009
      ALG6*
        ALG8*
            STT3A*
            STT3B*
            DDOST*
            MAGT1*
 
N00820    G00009−MOGS⇉GANAB⇉MAN1⇉MGAT1⇉MAN2⇉MGAT2⇉FUT8⇉B4GALT⇉ST6GAL→G00018
    CDG2B   MOGS*
    CDG2A             MGAT2*
    CDG2D                 B4GALT1*
 
N00824    GDP-Fuc−SLC35C1→GDP-Fuc(Golgi)
    CDG2C   SLC35C1*
 
N00826    UDP-Gal−SLC35A2→UDP-Gal(Golgi)
    CDG2M   SLC35A2*
 
N00828    CMP-Neu5Ac−SLC35A1→CMP-Neu5Ac(Golgi)
    CDG2F   SLC35A1*

Disease nameDisease category
CDG1BBH00118Congenital disorders of glycosylation type IInherited metabolic disorder
CDG1AAH00118Congenital disorders of glycosylation type IInherited metabolic disorder
CDG1DDH00118Congenital disorders of glycosylation type IInherited metabolic disorder
CDG1QH00118Congenital disorders of glycosylation type IInherited metabolic disorder
CDG1MH00118Congenital disorders of glycosylation type IInherited metabolic disorder
CDG1JH00118Congenital disorders of glycosylation type IInherited metabolic disorder
CDG1SH00118Congenital disorders of glycosylation type IInherited metabolic disorder
CDG1KH00118Congenital disorders of glycosylation type IInherited metabolic disorder
CDG1IH00118Congenital disorders of glycosylation type IInherited metabolic disorder
CDG1PH00118Congenital disorders of glycosylation type IInherited metabolic disorder
CDG1BH00118Congenital disorders of glycosylation type IInherited metabolic disorder
CDG1AH00118Congenital disorders of glycosylation type IInherited metabolic disorder
CDG1EH00118Congenital disorders of glycosylation type IInherited metabolic disorder
CDG1UH00118Congenital disorders of glycosylation type IInherited metabolic disorder
CDG1OH00118Congenital disorders of glycosylation type IInherited metabolic disorder
CDG1NH00118Congenital disorders of glycosylation type IInherited metabolic disorder
CDG1DH00118Congenital disorders of glycosylation type IInherited metabolic disorder
CDG1LH00118Congenital disorders of glycosylation type IInherited metabolic disorder
CDG1GH00118Congenital disorders of glycosylation type IInherited metabolic disorder
CDG1TH00118Congenital disorders of glycosylation type IInherited metabolic disorder
CDG1CH00118Congenital disorders of glycosylation type IInherited metabolic disorder
CDG1HH00118Congenital disorders of glycosylation type IInherited metabolic disorder
CDG1WARH00118Congenital disorders of glycosylation type IInherited metabolic disorder
CDG1XH00118Congenital disorders of glycosylation type IInherited metabolic disorder
CDG1RH00118Congenital disorders of glycosylation type IInherited metabolic disorder
CDG1CC H00118Congenital disorders of glycosylation type IInherited metabolic disorder
CDG2BH00119Congenital disorders of glycosylation type IIInherited metabolic disorder
CDG2AH00119Congenital disorders of glycosylation type IIInherited metabolic disorder
CDG2DH00119Congenital disorders of glycosylation type IIInherited metabolic disorder
CDG2CH00119Congenital disorders of glycosylation type IIInherited metabolic disorder
CDG2MH00119Congenital disorders of glycosylation type IIInherited metabolic disorder
CDG2FH00119Congenital disorders of glycosylation type IIInherited metabolic disorder