KEGG   ORTHOLOGY: K09484
Entry
K09484                      KO                                     
Symbol
QUTB, QA-3
Name
quinate dehydrogenase [EC:1.1.1.24]
Pathway
map00400  Phenylalanine, tyrosine and tryptophan biosynthesis
map01100  Metabolic pathways
Reaction
R01872  L-quinate:NAD+ 3-oxidoreductase
Brite
KEGG Orthology (KO) [BR:ko00001]
 09100 Metabolism
  09105 Amino acid metabolism
   00400 Phenylalanine, tyrosine and tryptophan biosynthesis
    K09484  QUTB, QA-3; quinate dehydrogenase
Enzymes [BR:ko01000]
 1. Oxidoreductases
  1.1  Acting on the CH-OH group of donors
   1.1.1  With NAD+ or NADP+ as acceptor
    1.1.1.24  quinate/shikimate dehydrogenase (NAD+)
     K09484  QUTB, QA-3; quinate dehydrogenase
Other DBs
GO: 0030266
Genes
DHA: DEHA2C03674g
PIC: PICST_30813
CTEN: CANTEDRAFT_91884
CAUR: CJI96_0000391
OPA: HPODL_00009
NCR: NCU06025(qa-3)
NTE: NEUTE1DRAFT46730(NEUTE1DRAFT_46730)
SMP: SMAC_07403(qa3)
PAN: PODANSg2393
PBEL: QC761_505110(QA3)
PPSD: QC762_505110(QA3)
PPSP: QC763_505110(QA3)
PPSA: QC764_505110(QA3)
TTT: THITE_2116892
MTM: MYCTH_2309055
CTHR: CTHT_0047970
MGR: MGG_07781
PPEI: PpBr36_03790
PGRI: PgNI_09286
SSCK: SPSK_00849 SPSK_06463
FGR: FGSG_03880 FGSG_05704 FGSG_12357
FPU: FPSE_06307 FPSE_06596 FPSE_06601
FPOA: FPOAC1_006297 FPOAC1_006302 FPOAC1_008652(QA3)
FVN: FVRRES_06901 FVRRES_06906 FVRRES_09249
FVR: FVEG_05965 FVEG_09879
FOX: FOXG_04621 FOXG_08708 FOXG_10944
NHE: NECHADRAFT_32803 NECHADRAFT_51161
FFC: NCS54_00213200 NCS54_01291000
FKR: NCS57_00208300
FMU: J7337_000083 J7337_004802(QA3)
TRE: TRIREDRAFT_109687
TRR: M419DRAFT_131881
MAW: MAC_04533
MAJ: MAA_07943
PCHM: VFPPC_13532
CMT: CCM_06001
AMUS: LMH87_005397
PLJ: VFPFJ_10299
PTKZ: JDV02_003520
VAL: VDBG_08510
VDA: VDAG_08175
CFJ: CFIO01_01549 CFIO01_09601
CLUP: CLUP02_09230 CLUP02_14466
CHIG: CH63R_14195
SAPO: SAPIO_CDS6511
ELA: UCREL1_1141 UCREL1_7618
PFY: PFICI_03111 PFICI_14932 PFICI_15086
SSL: SS1G_09188
BFU: BCIN_06g00810
MBE: MBM_00576 MBM_09548
PSCO: LY89DRAFT_635429 LY89DRAFT_680000 LY89DRAFT_698602
GLZ: GLAREA_11530
ANI: ANIA_01137
AFM: AFUA_1G11590 AFUA_3G14800
ACT: ACLA_024050
NFI: NFIA_013950
AOR: AO090038000263 AO090103000428 AO090103000431
ANG: An03g03710 An04g08100
AFV: AFLA_008750 AFLA_013099 AFLA_013104
ALUC: AKAW2_30242S AKAW2_50769A
ACHE: ACHE_30247S ACHE_80025A
APUU: APUU_30054A APUU_31273S APUU_50617S
PCS: N7525_003333
PDP: PDIP_30870
POU: POX_d05553
TMF: EYB26_001333 EYB26_002338
TRG: TRUGW13939_02954 TRUGW13939_04943
PNO: SNOG_10413 SNOG_11439
PTE: PTT_10795
BZE: COCCADRAFT_83737
BSC: COCSADRAFT_107251
BOR: COCMIDRAFT_39029
AALT: CC77DRAFT_994183
ARAB: EKO05_0007380
ZTR: MYCGRDRAFT_84424(qa-3)
PFJ: MYCFIDRAFT_84957
FFU: CLAFUR5_10641
CBET: CB0940_06130
BCOM: BAUCODRAFT_32361
NPA: UCRNP2_4112
CCAC: CcaHIS019_0606160(CcaverHIS019_0606160)
SHS: STEHIDRAFT_87473
HIR: HETIRDRAFT_476563
RSX: RhiXN_08452
UMA: UMAG_05412
PFP: PFL1_00209
SGRA: EX895_002614
 » show all
Reference
PMID:2976880
  Authors
Hawkins AR, Lamb HK, Smith M, Keyte JW, Roberts CF
  Title
Molecular organisation of the quinic acid utilization (QUT) gene cluster in Aspergillus nidulans.
  Journal
Mol Gen Genet 214:224-31 (1988)
DOI:10.1007/BF00337715
  Sequence
[ani:ANIA_01137]
LinkDB

KEGG   ENZYME: 1.1.1.24
Entry
EC 1.1.1.24                 Enzyme                                 
Name
quinate/shikimate dehydrogenase (NAD+);
quinate dehydrogenase (ambiguous);
quinic dehydrogenase (ambiguous);
quinate:NAD oxidoreductase;
quinate 5-dehydrogenase (ambiguous);
quinate:NAD+ 5-oxidoreductase
Class
Oxidoreductases;
Acting on the CH-OH group of donors;
With NAD+ or NADP+ as acceptor
Sysname
L-quinate:NAD+ 3-oxidoreductase
Reaction(IUBMB)
L-quinate + NAD+ = 3-dehydroquinate + NADH + H+ [RN:R01872]
Reaction(KEGG)
R01872;
(other) R06847
Substrate
L-quinate [CPD:C00296];
NAD+ [CPD:C00003]
Product
3-dehydroquinate [CPD:C00944];
NADH [CPD:C00004];
H+ [CPD:C00080]
Comment
The enzyme, found mostly in bacteria (mostly, but not exclusively in Gram-positive bacteria), fungi, and plants, participates in the degradation of quinate and shikimate with a strong preference for NAD+ as a cofactor. While the enzyme can act on both quinate and shikimate, activity is higher with the former. cf. EC 1.1.5.8, quinate/shikimate dehydrogenase (quinone), EC 1.1.1.282, quinate/shikimate dehydrogenase [NAD(P)+], and EC 1.1.1.25, shikimate dehydrogenase (NADP+).
History
EC 1.1.1.24 created 1961, modified 1976, modified 2004, modified 2021
Pathway
ec00400  Phenylalanine, tyrosine and tryptophan biosynthesis
ec01100  Metabolic pathways
Orthology
K09484  quinate dehydrogenase
K25901  quinate/shikimate dehydrogenase (NAD+)
Genes
DHA: DEHA2C03674g
PIC: PICST_30813
CTEN: CANTEDRAFT_91884
CAUR: CJI96_0000391
OPA: HPODL_00009
NCR: NCU06025(qa-3)
NTE: NEUTE1DRAFT46730(NEUTE1DRAFT_46730)
SMP: SMAC_07403(qa3)
PAN: PODANSg2393
PBEL: QC761_505110(QA3)
PPSD: QC762_505110(QA3)
PPSP: QC763_505110(QA3)
PPSA: QC764_505110(QA3)
TTT: THITE_2116892
MTM: MYCTH_2309055
CTHR: CTHT_0047970
MGR: MGG_07781
PPEI: PpBr36_03790
PGRI: PgNI_09286
SSCK: SPSK_00849 SPSK_06463
FGR: FGSG_03880 FGSG_05704 FGSG_12357
FPU: FPSE_06307 FPSE_06596 FPSE_06601
FPOA: FPOAC1_006297 FPOAC1_006302 FPOAC1_008652(QA3)
FVN: FVRRES_06901 FVRRES_06906 FVRRES_09249
FVR: FVEG_05965 FVEG_09879
FOX: FOXG_04621 FOXG_08708 FOXG_10944
NHE: NECHADRAFT_32803 NECHADRAFT_51161
FFC: NCS54_00213200 NCS54_01291000
FKR: NCS57_00208300
FMU: J7337_000083 J7337_004802(QA3)
TRE: TRIREDRAFT_109687
TRR: M419DRAFT_131881
MAW: MAC_04533
MAJ: MAA_07943
PCHM: VFPPC_13532
CMT: CCM_06001
AMUS: LMH87_005397
PLJ: VFPFJ_10299
PTKZ: JDV02_003520
VAL: VDBG_08510
VDA: VDAG_08175
CFJ: CFIO01_01549 CFIO01_09601
CLUP: CLUP02_09230 CLUP02_14466
CHIG: CH63R_14195
SAPO: SAPIO_CDS6511
ELA: UCREL1_1141 UCREL1_7618
PFY: PFICI_03111 PFICI_14932 PFICI_15086
SSL: SS1G_09188
BFU: BCIN_06g00810
MBE: MBM_00576 MBM_09548
PSCO: LY89DRAFT_635429 LY89DRAFT_680000 LY89DRAFT_698602
GLZ: GLAREA_11530
ANI: ANIA_01137
AFM: AFUA_1G11590 AFUA_3G14800
ACT: ACLA_024050
NFI: NFIA_013950
AOR: AO090038000263 AO090103000428 AO090103000431
ANG: An03g03710 An04g08100
AFV: AFLA_008750 AFLA_013099 AFLA_013104
ALUC: AKAW2_30242S AKAW2_50769A
ACHE: ACHE_30247S ACHE_80025A
APUU: APUU_30054A APUU_31273S APUU_50617S
PCS: N7525_003333
PDP: PDIP_30870
POU: POX_d05553
TMF: EYB26_001333 EYB26_002338
TRG: TRUGW13939_02954 TRUGW13939_04943
PNO: SNOG_10413 SNOG_11439
PTE: PTT_10795
BZE: COCCADRAFT_83737
BSC: COCSADRAFT_107251
BOR: COCMIDRAFT_39029
AALT: CC77DRAFT_994183
ARAB: EKO05_0007380
ZTR: MYCGRDRAFT_84424(qa-3)
PFJ: MYCFIDRAFT_84957
FFU: CLAFUR5_10641
CBET: CB0940_06130
BCOM: BAUCODRAFT_32361
NPA: UCRNP2_4112
CCAC: CcaHIS019_0606160(CcaverHIS019_0606160)
SHS: STEHIDRAFT_87473
HIR: HETIRDRAFT_476563
RSX: RhiXN_08452
UMA: UMAG_05412
PFP: PFL1_00209
SGRA: EX895_002614
SRR: SerAS9_2492
SRL: SOD_c23570(aroE1)
SRY: M621_12875
SPLY: Q5A_013025(aroE_1)
SRS: SerAS12_2493
SRA: SerAS13_2494
SFO: Z042_00790
VNA: PN96_18520
VEJ: VEJY3_18086
VFL: AL536_10335
PAE: PA0244
PAEV: N297_250
PAEI: N296_250
PAU: PA14_03020(aroE)
PAP: PSPA7_0329
PAG: PLES_02411
PAF: PAM18_0240
PNC: NCGM2_0250(aroE)
PAEB: NCGM1900_0235(aroE)
PDK: PADK2_01210
PSG: G655_01210
PRP: M062_01200
PAEP: PA1S_01255
PAER: PA1R_gp3758
PAEM: U769_01225
PAEL: T223_01210
PAES: SCV20265_0248
PAEU: BN889_00293
PAEG: AI22_02690
PAEC: M802_249
PAEO: M801_250
PMK: MDS_4143
PRE: PCA10_26230
PFUW: KF707C_28210
PCQ: PcP3B5_36090(aroE_2)
PMUI: G4G71_15935
PNT: G5B91_16140
PPAA: B7D75_01235
PPU: PP_2406
PPF: Pput_3289
PPG: PputGB1_2040
PPW: PputW619_1912
PPT: PPS_1993
PPB: PPUBIRD1_3278(aroE_3)
PPI: YSA_01027
PPX: T1E_5274
PPUH: B479_09845
PPUT: L483_09770
PPUN: PP4_34090
PPUD: DW66_2247
PFV: Psefu_2606
PMON: X969_07925
PMOT: X970_07900
PPJ: RK21_03038
POR: APT59_19470
PMOL: CLJ08_23645
PALD: LU682_018950
PIX: RIN61_21340
PMOS: O165_006915
PST: PSPTO_2348
PSB: Psyr_2132
PSYR: N018_09990
PSP: PSPPH_2107
PAMG: BKM19_013400
PCI: PCH70_29500
PAVL: BKM03_17595
PVD: CFBP1590__2183(aroE)
PCAB: JGS08_16195
PCOF: POR16_10150
PTRE: I9H09_14835
PSYI: MME58_10925
PAST: N015_16060
PLIJ: KQP88_13965
PFL: PFL_5382(aroE)
PPRC: PFLCHA0_c53540(aroE2)
PPRO: PPC_5354
PFE: PSF113_5094
PFN: HZ99_13190
PFO: Pfl01_4903(aroE)
PFS: PFLU_5365(aroE)
PFC: PflA506_4651(aroE)
PPZ: H045_17240
PFB: VO64_2201
PMAN: OU5_4277
PTV: AA957_18295
PCG: AXG94_11380
PVR: PverR02_27465
PAZO: AYR47_02890
POI: BOP93_22525
PRX: HRH33_23350
PMED: E3Z27_24450
PKR: AYO71_26425
PMUD: NCTC8068_04581(aroE2)
PTOL: I7845_25170
PFW: PF1751_v1c47820(aroE)
PFF: PFLUOLIPICF712040
PFX: A7318_24445
PEN: PSEEN2020
PLUL: FOB45_05210
PBA: PSEBR_a4908
PBC: CD58_25700
PPUU: PputUW4_04721(aroE2)
PSV: PVLB_14625
PSK: U771_27605
PKC: PKB_2854(aroe3)
PCH: EY04_27295
PCZ: PCL1606_08840
PCP: JM49_04410
PCHP: C4K32_5464
PALK: PSAKL28_46430
PRH: LT40_19550
PPV: NJ69_07395
PSES: PSCI_3913
PSEM: TO66_27300
PSEC: CCOS191_3120(aroE2)
PSOS: POS17_5342
PFK: PFAS1_15210
PANR: A7J50_5080
PPSL: BJP27_11410
PSET: THL1_2538
PSIL: PMA3_02960
PYM: AK972_0562
PKE: DLD99_24960
PALL: UYA_20250
PUM: HGP31_27245
POJ: PtoMrB4_30530(aroE_2)
PGY: AWU82_16660
PLAL: FXN65_14975
PSEJ: HNQ25_05410
PVK: EPZ47_25765
PEZ: HWQ56_25095
PBZ: GN234_22355
PTY: JWV26_06320
PMAO: PMYSY11_2178(aroE)
PATA: JWU58_04510
PDW: BV82_0037
PZE: HU754_026040
PMOE: HV782_025280
PVW: HU752_004900
PTRT: HU722_0025755
PXA: KSS93_17230
PSAM: HU731_011890
PTZ: HU718_026470
PQI: KH389_03380
PSHH: HU773_024245
PXN: HU772_012935
PHV: HU739_025225
PPRG: HU725_009140
PANH: HU763_009955
PASG: KSS96_24765
PFAK: KSS94_14320
PMUY: KSS95_14485
PMAM: KSS90_11145
PAZE: KSS91_25115
PALV: KSS97_25135
PORY: EJA05_11990
PWZ: J7655_17725
PTK: EXN22_04970
PTW: TUM18999_29460(aroE_3)
PZA: HU749_025880
PIE: HU724_024500
PWY: HU734_014425
PTAE: NCTC10697_00709(aroE_2)
PGF: J0G10_26850
PCAV: D3880_08840
PJU: L1P09_15005
PIZ: LAB08_R53100
PPEG: KUA23_26130
PSII: NF676_23450
PSIH: LOY51_11845
PCAS: LOY40_25015
PFIT: KJY40_26270
PASI: LG197_14820
PKM: PZ739_09525
PNB: NK667_31870
PSOA: PSm6_53400(aroE_3)
PTAI: ICN73_16105
PKK: QQ992_09900
PHYG: JTY93_22970
PHOM: KJF94_22690
PCHE: QYM18_03825
PCUC: PSH97_24240
PPAE: LDL65_07255
PPAO: K3169_10910
PRHZ: CRX69_23335
PSJY: AA098_10805
PSKU: KUIN1_21230(aroE_2)
AVN: Avin_38080
AVL: AvCA_38080
AVD: AvCA6_38080
ACX: Achr_12150
PDEN: F1C79_07845
ALR: DS731_17010
CSA: Csal_0293
HAK: KO116_00154
HAM: HALO0078
HHU: AR456_17795
HMD: CTT34_17695
HPRO: LMS44_23345
HHAO: QWG60_01680
HASO: B2G49_18455
HOL: HORIV_71380
HSR: HSBAA_65470
HPIZ: GYM47_17285
HNP: SR894_21850
HTT: HZS52_05170
HTX: EKK97_10020 EKK97_21495
SAJS: QO259_01825
MMW: Mmwyl1_3919
MME: Marme_1424
MPC: Mar181_0397
MPRI: MP3633_0460
MARD: IBG28_03005
MFOI: JSY38_12290
MPRF: J8N69_06090
MPON: MACH16_05450
MARS: A8C75_03190 A8C75_03735
GSN: YC6258_01690
LLP: GH975_03110
VFF: VITFI_CDS3289
AMAH: DLM_2147
AQS: DKK66_18620
RSO: RSp1398(aroE2)
RSE: F504_4864
RPU: CDC45_24665
RNC: GO999_20895
RSL: RPSI07_mp1386(aroE)
RSN: RSPO_m00665(aroE)
RSM: CMR15_mp30057(aroE)
RSG: JK151_16930
BMA: BMAA0850
BMV: BMASAVP1_1754
BML: BMA10229_2206
BMN: BMA10247_A0893
BMAE: DM78_4000
BMAI: DM57_09825
BMAF: DM51_4546
BMAZ: BM44_4880
BMAB: BM45_3782
BPS: BPSS0341(aroE)
BPM: BURPS1710b_A1897(aroE)
BPL: BURPS1106A_A0483(aroE)
BPD: BURPS668_A0580(aroE)
BPSE: BDL_3573
BPSM: BBQ_5858
BPSU: BBN_3737
BPSD: BBX_5411
BPZ: BP1026B_II0370
BPQ: BPC006_II0460
BPK: BBK_5553
BPSH: DR55_5006
BPSA: BBU_5776
BPSO: X996_4775
BUT: X994_4275
BTE: BTH_II2057
BTQ: BTQ_5337
BTJ: BTJ_3989
BTZ: BTL_4813
BTD: BTI_4389
BTV: BTHA_5417
BTHE: BTN_4463
BTHM: BTRA_4728
BTHA: DR62_4577
BTHL: BG87_4794
BOK: DM82_4416
BOC: BG90_6154
BUU: WS70_19200
BSAV: WS86_20545
BHG: I6G56_31120
BUD: AQ610_21295
BVI: Bcep1808_3551
BVE: AK36_3208
BUR: Bcep18194_B0345
BCM: Bcenmc03_4965
BCH: Bcen2424_5303
BCJ: BCAM2501(aroE)
BCEN: DM39_5336
BCEW: DM40_3153
BCEO: I35_6401(aroE)
BAM: Bamb_4664 Bamb_5913
BAC: BamMC406_5192
BMJ: BMULJ_05108(aroE)
BMU: Bmul_3420
BMK: DM80_4803
BMUL: NP80_5129
BCT: GEM_5894
BCED: DM42_5473
BCEP: APZ15_23060
BDL: AK34_3328
BPYR: ABD05_23050
BCON: NL30_16335
BUB: BW23_3722 BW23_5798
BDF: WI26_25325
BLAT: WK25_28355
BTEI: WS51_09460
BSEM: WJ12_32565
BPSL: WS57_01610
BMEC: WJ16_31040
BSTG: WT74_31390
BSTL: BBJ41_26485
BANN: JFN94_16870
BARI: NLX30_24605
BAEN: L3V59_27495
BGL: bglu_2g03870
BGU: KS03_5533
BUG: BC1001_4109
BGF: BC1003_5307
BGD: bgla_2g05580
BGO: BM43_4188
BYI: BYI23_A007640
BUK: MYA_3179
BUE: BRPE67_ACDS07620(aroE)
BUL: BW21_3922
BUQ: AC233_29060
BGP: BGL_2c04790(aroE2)
BPLA: bpln_2g05340
BURK: DM992_24190
BXE: Bxe_B0884
BXB: DR64_6205
BGE: BC1002_4378
BPX: BUPH_00691
BPY: Bphyt_4569
BUZ: AYM40_30940
BFN: OI25_6636
PSPW: BJG93_24235
PARB: CJU94_24625
PGP: CUJ91_27155
PCJ: CUJ87_17850
PTS: CUJ90_19420
PCAF: DSC91_000926
PMEG: FNZ07_01505
PTRO: G5S35_36570
PGIS: I6I06_25150
PACP: FAZ97_31925
PACS: FAZ98_32385
PDIO: PDMSB3_2300.1(aroE)
PBRY: NDK50_25460
PKF: RW095_10990
PPAI: E1956_39095
PAND: DRB87_20845
PLG: NCTC10937_03700(aroE_2)
BUO: BRPE64_ACDS08590
CABK: NK8_08380
TVL: FAZ95_32735
TCAR: U0034_22065
BOJ: CBF45_02385
CDN: BN940_00686
KGY: EHF36_02780
ACK: C380_23180
ARAD: KI609_22035
MLIR: LPB04_18595
AON: DEH84_10705
AZA: AZKH_p0471(aroE)
THU: AC731_016930
THAU: C4PIVTH_0856(aroE)
BEBA: BWI17_06815
MOP: Mesop_2760
MAMO: A6B35_12285
MESM: EJ066_01655 EJ066_30260
MESR: FGU64_18860
MOH: IHQ72_13525
MMEI: LRP31_31000
MESO: BSQ44_01550
PHT: BLM14_17570 BLM14_19965
PHYL: HB779_22995
NIY: FQ775_15050
SME: SM_b20037(aroE2)
SMK: Sinme_4133
SMQ: SinmeB_4629
SMX: SM11_pD0010(aroE2)
SMI: BN406_05097(aroE)
SMEG: C770_GR4pD0011
SMEL: SM2011_b20037(aroE2)
SMER: DU99_25515
SMD: Smed_5698
RHI: NGR_b00200 NGR_b06000
SFH: SFHH103_06819
SFD: USDA257_c22240(aroE1) USDA257_c56320(aroE2)
SIX: BSY16_5041
SAME: SAMCFNEI73_pC0018(aroE)
SINO: SS05631_b49820 SS05631_b63110
ESJ: SJ05684_b47210 SJ05684_b53920
EAK: EKH55_1601 EKH55_4826
EMX: FKV68_32805
ENU: PYH37_001683
EGI: PZN02_005180
SKM: PZL22_000815
STEG: QA637_20350
EAD: OV14_a1268
EAH: FA04_32175
ECAA: J3R84_21425
ENP: JVX98_28580
ATU: Atu4532(aroE)
ATA: AWN88_10320
AGR: AGROH133_13894
ATF: Ach5_42290(aroE)
AGC: BSY240_2611
AGT: EYD00_14830
ARUI: G6M88_16385
AVQ: HRR99_17595
AVV: RvVAT039_38280(aroE)
AVF: RvVAR031_41320(aroE)
RIR: BN877_II0219(aroE2)
RPUS: CFBP5875_14980
ACUC: KZ699_22660
ALEG: CFBP4996_24005
AVI: Avi_5454(aroE)
RET: RHE_CH02291(aroEch2) RHE_PC00214(aroEc)
REL: REMIM1_CH02301(aroE-2) REMIM1_PB00219(aroE-3)
REP: IE4803_CH01956(aroE-2) IE4803_PD00660(aroE-3)
REI: IE4771_CH02031(aroE-2) IE4771_PE00684(aroE-3)
RLT: Rleg2_3465
RLU: RLEG12_21050
RTR: RTCIAT899_PC05330 RTCIAT899_PC07925
RGA: RGR602_PC02220(aroE-2)
RHN: AMJ98_CH02346(aroE-2) AMJ98_PB00285(aroE-3)
RPHA: AMC79_CH03887(aroE-2) AMC79_PA00326(aroE-3)
RHX: AMK02_CH02362(aroE-2) AMK02_PB00300(aroE-3)
RHV: BA939_25910
RHK: Kim5_CH02056(aroE-2) Kim5_PD00633(aroE-3)
REZ: AMJ99_CH02424(aroE-2) AMJ99_PA00285(aroE-3)
RHR: CKA34_29330
ROY: G3A56_24505
RHID: FFM81_009860
RBQ: J2J99_09965 J2J99_26870
RLN: J0663_20970 J0663_29630
RBAN: J2J98_29090
RLS: HB780_04215
RROS: D4A92_07705
RAW: NE851_01455
RSUL: N2599_20680
RCT: PYR68_08115
ARA: Arad_7777(aroEc)
ARO: B0909_14870
NGL: RG1141_CH22140
NEO: CYG48_19360
NPM: QEO92_11760
RHT: NT26_0312(aroE)
RFV: RFYW14_00591
SOJ: K6301_18725 K6301_20725 K6301_22005
SSUM: Q9314_19400 Q9314_21180 Q9314_26130
ABAW: D5400_07000
PDES: FE840_019145
OIN: IAR37_14160
OAN: Oant_4426
OAH: DR92_3819
BPSN: NIK97_16240
OCR: HGK82_15250
OCL: GTN27_12805
BJA: bll1059(aroE) bll6391(aroE)
BJU: BJ6T_10850
BJP: RN69_05295
BRA: BRADO5598
BBT: BBta_6119
BRS: S23_67540(aroE)
AOL: S58_20090
BRC: BCCGELA001_34360
BIC: LMTR13_30170
BRO: BRAD285_1609(aroE) BRAD285_3019(aroE)
BRK: CWS35_04590
BOT: CIT37_01000
BRQ: CIT40_30150
BGQ: X265_05330 X265_34730
BGZ: XH91_05355 XH91_33120
BSYM: CIT39_29285
BBET: F8237_13120
BARH: WN72_46280
BVZ: BRAD3257_6024(aroE) BRAD3257_8666(aroE)
BEL: BE61_11000(aroE)
BDG: LPJ38_02230
BSEP: HAP48_0017345
BQB: J4P68_0020890
BSEI: KMZ68_01605
BBAN: J4G43_050785
BCAN: BcanWSM471_35530
BAUT: QA635_41010
BGK: IC762_02850
BCOU: IC761_34720
BPAH: QA639_41160
BXN: I3J27_37670
BROS: QUH67_34010
BRAZ: LRP30_29860 LRP30_42230
RBK: E0H22_07575
VGO: GJW-30_1_01140(aroE_2)
TRB: HB776_29265
BOS: BSY19_2154
BVV: BHK69_16495
BOI: BLM15_13550
BOF: FQV39_13450
BVES: QO058_24235
MET: M446_4753
MNO: Mnod_0118 Mnod_0120
MAQU: Maq22A_c10215(aroE) Maq22A_c19135(aroE)
MEE: DA075_08870 DA075_24535
MTEA: DK419_05545 DK419_21185
MIND: mvi_02410(aroE_1) mvi_33050(aroE_3)
MOC: BB934_22135 BB934_24965
MTEZ: HPT29_004335
MLD: U0023_14245
CHEL: AL346_23315
PHL: KKY_192
PEM: OF122_04930
DEQ: XM25_01075
DEA: FPZ08_04000
DSAL: K1X15_06310
DEVO: H4N61_04435
DRH: JI748_03145
YTI: FNA67_04880
MHAR: L1P08_01980
HDI: HDIA_2135(aroE_1)
MMED: Mame_02255(aroE_2)
AUB: LXB15_03025
JAV: OXU80_01155
RBM: TEF_15285
PPHR: APZ00_24125
LAP: ACP90_08185 ACP90_08360
LABP: FJ695_22940
LABT: FIU93_13825(aroE2)
LAGG: B0E33_20240
RPOP: K1718_03205
SIW: GH266_20435
PHR: C6569_12820
PSTG: E8M01_24900
PAQT: E8L99_20195
BGOE: IFJ75_11145
SIL: SPO2425
KVL: KVU_2375
KVU: EIO_0027
KRO: BVG79_00492(aroE)
CID: P73_0153
CMAR: IMCC12053_267
MALG: MALG_04308
YPAC: CEW88_16985 CEW88_22640
YAN: AYJ57_19750
PABY: Ga0080574_TMP2880
SULZ: C1J03_16910
SULD: B5M07_19165
SPSE: SULPSESMR1_00067(aroE)
RID: RIdsm_00847(aroE_1)
AHT: ANTHELSMS3_04736
SAGU: CDO87_22940
OCD: FHY55_04795
ROT: FIV09_00180(aroE1)
RMH: LVO79_05975
MALU: KU6B_47460
HAT: RC74_13050
LSAL: KBK07_03125
TRY: QF118_04195
PLCG: RVY76_00470
MARU: FIU81_13570(aroE1)
FYT: QF092_12055
PZH: CX676_15720
PARO: CUV01_11550
PARR: EOJ32_02835
PLIA: E4191_19215
PMAU: CP157_03022(aroE_2)
PAEX: JHW48_17335
PALP: JHW40_19070
RHC: RGUI_2714
DAA: AKL17_3719
TEC: AKL02_012920
RBG: BG454_02255
GFU: KM031_17340
SALO: EF888_13035
SEDI: EBB79_14370
HML: HmaOT1_14065
LIT: FPZ52_14880
PPRU: FDP22_11930
PSHQ: F3W81_03735
PGV: SL003B_3183(aroE)
HDH: G5B40_03820
CMAG: CBW24_11500
ACRO: K3J57_00095
PBAE: P8S53_07140
LVR: T8T21_17895
RBX: I3V23_07580
NAR: Saro_1590
NPP: PP1Y_AT12412
NPN: JI59_22210
NOT: C7W88_09525
NOR: FA702_20405
NHUM: PQ457_09655
SPHC: CVN68_02860
SECH: B18_06690
SBIN: SBA_ch2_1490(aroE_1) SBA_ch2_3400(aroE_2)
SNAP: PQ455_14670
SDON: M9980_11075
SYA: A6768_16970
SPYG: YGS_C2P0952 YGS_C2P1151
POQ: KZX46_10990
PMEA: KTC28_17930
RGI: RGI145_19285
ROS: CTJ15_17230
RMUC: FOB66_21285
RMT: IAI58_06090
RFL: Rmf_43830(aroE_1)
RCV: PFY06_04880
ACIM: GT370_14830
STEL: STAQ_36940
AZL: AZL_c01580(aroE)
AOZ: HUE56_08025
AZS: E6C72_24240
NCB: C0V82_17955
SROE: JL101_034875
FER: FNB15_06815
TXI: TH3_00450
TII: DY252_21770
THAI: IT893_00495
TLU: R1T41_08975
TTB: MACH01_01000
NACI: NUH88_20890
THAR: T8K17_09310
PARH: I5S86_10430
MDX: BTO20_25545
MGAU: MGALJ_11380(aroE_2)
MVQ: MYVA_1532(aroE1)
MLL: B1R94_20840
MMAG: MMAD_03550(aroE_1)
MPSC: MPSYJ_49110
MARZ: MARA_04370(aroE_1)
MGAD: MGAD_12800(aroE_1)
MMAT: MMAGJ_48380(aroE_1)
MSEI: MSEDJ_10090(aroE_1)
MBRM: L2Z93_002211
MRF: MJO55_07765
CGL: Cgl0424(Cgl0424)
CGB: cg0504(aroE)
CGU: WA5_0409(AroE)
CGT: cgR_0495
CGS: C624_02475
CGG: C629_02475
CGM: cgp_0504
CGJ: AR0_02670
CGQ: CGLAR1_02535
CGX: SB89_02350
CEF: CE0443(aroE)
CHN: A605_12900
CMD: B841_00095
CCG: CCASEI_03735
CGY: CGLY_11595(aroE2)
CDX: CDES_02325(aroE)
CSTA: CSTAT_03275
CCJZ: ccrud_02210
CAMG: CAMM_03390
CSUR: N24_0563(aroE)
CCYC: SCMU_39920(aroE_2) SCMU_40300(aroE_3)
CPOY: GP475_09285
CFAC: CFAEC_01760(aroE1)
BFV: C628_02520
RHA: RHA1_ro01342(aroE1) RHA1_ro01853(aroE3)
RER: RER_38080 RER_46930
REY: O5Y_17580 O5Y_22160
REB: XU06_17790 XU06_22275
RQI: C1M55_18770 C1M55_23615
ROP: ROP_10580(aroE) ROP_15380(aroE) ROP_21990(aroE)
ROA: Pd630_LPD05461 Pd630_LPD06023
RPY: Y013_09920 Y013_14040
RBY: CEJ39_20805
RHB: NY08_388
RAV: AAT18_10970 AAT18_25260
RFA: A3L23_03714(aroE_1)
RHS: A3Q41_04526(aroE_2)
RRZ: CS378_00720 CS378_14840
RHQ: IM25_01750
RHOD: AOT96_03650 AOT96_29400
RRT: 4535765_03803(aroE_2)
RKO: JWS14_06905 JWS14_09520 JWS14_12960
RGO: KYT97_26160 KYT97_30380
ROZ: CBI38_11155 CBI38_24855
RPSK: JWS13_32905 JWS13_36315 JWS13_39525
RGOR: NMQ04_16630
GPO: GPOL_c35180(aroE2)
GOR: KTR9_3202
GOM: D7316_05043(aroE_2)
GOI: LK459_22220
SMA: SAVERM_1777(aroE2)
SGRF: SGFS_028670
SCB: SCAB_15781(aroE)
SHY: SHJG_7568
SHO: SHJGH_7329
SRC: M271_50395
SMAL: SMALA_4905
SSOI: I1A49_28550
SDV: BN159_1815(aroE)
SVT: SVTN_37120
SCW: TU94_28565
SAMB: SAM23877_6314(aroE)
SCX: AS200_10075
SLE: sle_11670(sle_11670)
SPAV: Spa2297_27665
STSI: A4E84_34060
SGM: GCM10017557_12750(aroE)
SCAD: DN051_08985
SPHW: NFX46_11855
SLS: SLINC_7056
SAUO: BV401_28275
SGE: DWG14_01551(aroE_1)
SGD: ELQ87_05910
SCYA: EJ357_39750
SAST: CD934_03835
SHAW: CEB94_34940
SGAL: CP966_30490
SPAD: DVK44_30730
SAQU: EJC51_38720
SPHV: F9278_40145 F9278_41605
SFUG: CNQ36_30540
SPAC: B1H29_05990
SCHA: CP983_07265
SCOE: CP976_36430
SBAT: G4Z16_02755
SBRO: GQF42_37160
STUI: GCM10017668_59870(aroE)
SFEU: IM697_29355
SVD: CP969_31915
SPRA: CP972_30595
SROI: IAG44_06740
SXN: IAG42_35030
SLF: JEQ17_09435
SDEC: L3078_38420
SDUR: M4V62_37915
SAKB: K1J60_06795
SCAE: IHE65_06340
SSPN: LXH13_32575
SCIR: STRCI_006737
SLON: LGI35_33740
SANT: QR300_16755
SJN: RI060_06440
SCYN: N8I84_33625
SKG: KJK29_04830
SCOA: QU709_05930
SINN: ABB07_05435
AGLA: OIE69_22575
LEIF: HF024_03830
LSE: F1C12_19630
MTS: MTES_3524
MIH: BJP65_01485
MAUR: BOH66_06235
MHOS: CXR34_05715 CXR34_10865
MPRT: ET475_04355
MCAW: F6J84_07905
MBIN: LXM64_08715
MTEC: OAU46_08330
MRG: SM116_09595
MINV: T9R20_09675
AARC: G127AT_09245
AMAV: GCM10025877_22880(aroE_2)
MYL: C3E77_01220
SALC: C2138_05390
SALD: FVA74_03545
LEB: G7066_01925
LVI: G7068_10910
LALL: MUN78_01210
LTN: KVY00_10585 KVY00_10615
ART: Arth_4080
ARR: ARUE_c41890(aroE2)
ARL: AFL94_05075 AFL94_14405
ARH: AHiyo8_36170
ARY: ATC04_03530 ATC04_12810
ARZ: AUT26_19095
ARU: ASPU41_05325
ARQ: BWQ92_10770
ARN: CGK93_22695
ACRY: AC20117_10665
ARTH: C3B78_19185
ARTP: E5206_03525 E5206_14090
AJG: KKR91_09620
ASUN: KG104_10035
ARTY: AHiyo4_50600
AWW: G8758_12020
ACAO: NF551_08110 NF551_14275
AZH: MUK71_08240
AGEG: MUG94_09330
AOD: Q8Z05_07475
AKO: N9A08_07810
AZX: N2K95_08095
AJR: N2K98_08705
AAU: AAur_4046(aroE)
PUE: FV140_20830
PNV: JMY29_13025 JMY29_19420
ACH: Achl_3856
APN: Asphe3_38880
PSUL: AU252_10730
PSNI: NIBR502771_05770
PSEY: GU243_16305
PDEL: JCQ34_19030
POK: SMD14_19835
GAR: AOZ07_14620
GCR: GcLGCM259_2463
GLU: F0M17_13980
GPR: JQN66_05515 JQN66_14430
GMI: NMP99_14595
GMY: XH9_11470
GNC: QQS42_14415
KPL: KPaMU14_10570
KFV: AS188_01875
KII: KocCE7_12080
KRS: EQG70_04025
KOD: HBK84_11950
RMU: RMDY18_00530
RTER: IDM49_00510
RKR: I6G21_01425
SATK: SA2016_3914 SA2016_3943
NAE: BHE16_08020
CIG: E7744_10615
CMUA: P8192_01890
BLY: A2T55_15545
BLIN: BLSMQ_3388
BSPO: L1F31_15915
PPC: HMPREF9154_1964
MPH: MLP_29170
RAIN: Rai3103_00170
NARO: CFH99_04015
NAQU: ENKNEFLB_00208(aroE_1)
NRO: K8W59_01505
NPS: KRR39_02465
MUZ: H4N58_14735
SGRG: L0C25_05970
NEC: KGD82_11625
SNAH: OUQ99_25230
SAIU: J4H86_00355
NOA: BKM31_07160
NGN: LCN96_34275
NFS: OIE67_10185
GOB: Gobs_2247
MMAR: MODMU_2945(aroE)
AMD: AMED_4360(aroE)
AMN: RAM_22205
AMM: AMES_4308(aroE)
AMZ: B737_4308(aroE)
AOI: AORI_3513(aroE)
AJA: AJAP_21575(aroE)
AMYC: CU254_25630
AMYB: BKN51_14910
AAB: A4R43_06640
AMYY: YIM_20095(aroE2)
AORI: SD37_18145
APRT: MUY14_09335
AROO: NQK81_04935
ARHD: VSH64_05395
PSEA: WY02_02035
PSEE: FRP1_10995
PSEH: XF36_10740 XF36_13835
PSEQ: AD006_19960
PECQ: AD017_27800
SSYI: EKG83_29670
KUT: JJ691_98840(aroE_3)
KBU: Q4V64_46305
ACTY: OG774_13365 OG774_28610
UME: RM788_49300
AMS: AMIS_66680
AFS: AFR_16070
ACTL: L3i22_063440(aroE)
ASIC: Q0Z83_040480 Q0Z83_102990
PLAB: C6361_15530
SNA: Snas_5094
JTL: M6D93_07005
DGE: Dgeo_2374
DDR: Deide_1p01400
SUS: Acid_3092
PFER: IRI77_21630
MICA: P0L94_18115
 » show all
Reference
1  [PMID:13208693]
  Authors
MITSUHASHI S, DAVIS BD.
  Title
Aromatic biosynthesis. XIII. Conversion of quinic acid to 5-dehydroquinic acid by quinic dehydrogenase.
  Journal
Biochim Biophys Acta 15:268-80 (1954)
DOI:10.1016/0006-3002(54)90069-4
Reference
2
  Authors
Gamborg, O.L.
  Title
Aromatic metabolism in plants. III. Quinate dehydrogenase from mung bean cell suspension cultures.
  Journal
Biochim Biophys Acta 128:483-491 (1966)
Reference
3  [PMID:7049157]
  Authors
Hawkins AR, Giles NH, Kinghorn JR.
  Title
Genetical and biochemical aspects of quinate breakdown in the filamentous fungus Aspergillus nidulans.
  Journal
Biochem Genet 20:271-86 (1982)
DOI:10.1007/BF00484424
Reference
4  [PMID:18669580]
  Authors
Singh S, Stavrinides J, Christendat D, Guttman DS.
  Title
A phylogenomic analysis of the shikimate dehydrogenases reveals broadscale functional diversification and identifies one functionally distinct subclass.
  Journal
Mol Biol Evol 25:2221-32 (2008)
DOI:10.1093/molbev/msn170
Reference
5  [PMID:19376919]
  Authors
Teramoto H, Inui M, Yukawa H.
  Title
Regulation of expression of genes involved in quinate and shikimate utilization in Corynebacterium glutamicum.
  Journal
Appl Environ Microbiol 75:3461-8 (2009)
DOI:10.1128/AEM.00163-09
  Sequence
[cgt:cgR_0495]
Reference
6  [PMID:23306642]
  Authors
Kubota T, Tanaka Y, Hiraga K, Inui M, Yukawa H.
  Title
Characterization of shikimate dehydrogenase homologues of Corynebacterium glutamicum.
  Journal
Appl Microbiol Biotechnol 97:8139-49 (2013)
DOI:10.1007/s00253-012-4659-y
  Sequence
[cgt:cgR_0495]
Reference
7  [PMID:25524738]
  Authors
Peek J, Christendat D.
  Title
The shikimate dehydrogenase family: functional diversity within a conserved structural and mechanistic framework.
  Journal
Arch Biochem Biophys 566:85-99 (2015)
DOI:10.1016/j.abb.2014.12.006
Other DBs
ExplorEnz - The Enzyme Database: 1.1.1.24
IUBMB Enzyme Nomenclature: 1.1.1.24
ExPASy - ENZYME nomenclature database: 1.1.1.24
BRENDA, the Enzyme Database: 1.1.1.24
CAS: 9028-28-8
LinkDB

KEGG   REACTION: R01872
Entry
R01872                      Reaction                               
Name
L-quinate:NAD+ 3-oxidoreductase;
quinate:NAD+ 5-oxidoreductase
Definition
Quinate + NAD+ <=> 3-Dehydroquinate + NADH + H+
Equation
C00296 + C00003 <=> C00944 + C00004 + C00080
Comment
3-Dehydroquinate was formerly called "5-Dehydroquinate" on old nomenclature system of numbering
Reaction class
RC00001  C00003_C00004
RC00154  C00296_C00944
Enzyme
1.1.1.24        1.1.1.282
Pathway
rn00400  Phenylalanine, tyrosine and tryptophan biosynthesis
rn01100  Metabolic pathways
Brite
Enzymatic reactions [BR:br08201]
 1. Oxidoreductase reactions
  1.1  Acting on the CH-OH group of donors
   1.1.1  With NAD+ or NADP+ as acceptor
    1.1.1.24
     R01872  Quinate + NAD+ <=> 3-Dehydroquinate + NADH + H+
    1.1.1.282
     R01872  Quinate + NAD+ <=> 3-Dehydroquinate + NADH + H+
Orthology
K05887  quinate/shikimate dehydrogenase [EC:1.1.1.282]
K09484  quinate dehydrogenase [EC:1.1.1.24]
K25901  quinate/shikimate dehydrogenase (NAD+) [EC:1.1.1.24]
Other DBs
RHEA: 22367
LinkDB

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