Anser cygnoides domesticus (swan goose): 106031696 Help Entry 106031696         CDS       T04896                                  Symbol RYR3 Name (RefSeq) ryanodine receptor 3 isoform X15   KO K04963   ryanodine receptor 3 Organism acyg  Anser cygnoides domesticus (swan goose) Pathway acyg04020   Calcium signaling pathway acyg04371   Apelin signaling pathway Brite KEGG Orthology (KO) [BR:acyg00001]  09130 Environmental Information Processing   09132 Signal transduction    04371 Apelin signaling pathway     106031696 (RYR3)    04020 Calcium signaling pathway     106031696 (RYR3)  09180 Brite Hierarchies   09183 Protein families: signaling and cellular processes    04040 Ion channels [BR:acyg04040]     106031696 (RYR3) Ion channels [BR:acyg04040]  Voltage-gated cation channels   Ryanodine receptor    106031696 (RYR3) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  RYDR_Jsol RYDR_ITPR RyR RR_TM4-6 MIR SPRY Ins145_P3_rec RIH_assoc Ion_trans EF-hand_7 EF-hand_1 EF-hand_6 EF-hand_8 TBK1_ULD Motif Other DBs NCBI-GeneID:  106031696 NCBI-ProteinID:  XP_013029687 LinkDB All DBs Position Unknown AA seq 4868 aa AA seqDB search MAEGGEGGEDEIQFLRTDDEVVLQCVASVHKEQRKFCLAAEGLGNRLCFLEPTSEAKYVP PDLCICNFVLEQSLSVRALQEMLANTGDNASEGAAQGGHRTLLYGHAILLRHSFSEMYLT CLTSSRSQTDKLAFDVGLRENAAGEACWWTIHPASKQRSEGEKVRIGDDLILVSVSSERY LHLSMSNGSIQVDASFMQTLWNVHPTCSGSNITEGYLLGGHVVRFFHGHDECLTIPSTDQ NDSQQKKVLYETGGAGVRARSLWRVEPLRISWSGSNIKWGQPFRLRHITTGMYLALNDDE GLVMLDREKSDTTSTAFCFRASKELKEKQDSTLKRDIDGMGVPEIKYGDSVCFVQHVASA LWLTYKAQDAKSARLGLLKRKVILHQEGHMDDGLTLQRCQHEESQAARIIRNTTSLFSQF LSGNNRTLSPIALPVEEMAQTLQDLITYFQPPEEDLEHEDKQSKLRSLKNRQNLFKEEGM LALVLNCIDRLNDSNSAAHFAEIAREENGTTWKEILNLLYKLLAALIRGNRNNCTQFSSN LDWLISKLDRLESSSGILEVLHCILIESPEALNIIAEEHIKSIISLLDKHGRNYKVLDVL CSLCVCNGVAVRANQNLICDNLLPRRDLLLQTRLINDVTSIRPNIFLGVAEGSAQYKKWY FELIIDQVDPFLTAEPTHLRVGWASTSGYAPYPGGGEGWGGNGVGDDLYSYGFDGLHLWS GRVPRAVASVNQHLLSSDDVVSCCLDLGVPSISFRINGQPVQGMFENFCTEGFFFPVVSL SAGVKARFLLGGRHGEFKFLPPAGYAPCYEALLPKEKMKLEPVKEYKRDSDGVRDLLGTT QFLSQASFIPCPIDTSQIALPFHLEKIRDKLAENIHELWGMNKIELGWTYGKIRDDNKRH HPCLVEFSKLPETEKNYNLQMSTETLKTLLALGCHIVHANPAAEEDLKKVKLPKNYMMSN GYKPAPLDLSEVKLLPSQEFLVDKLAENAHNVWAKDRIKQGWTYGIQQDLKNKRNPRLVP YALLDERTKKSNRDSLREAVRTFAGYGYSVEPPDQEIADQTTEKVSIDKIRFFRVEQSYA VKSGKWYFEFEAVTGGDMRVGWARPGCRPDIELGADDQAFVFEGSKGQRWHQGSGFFGRS WQPGDVVGCMINLDDKSIIFTLNGELLITSKGSELAFADFGIESGFVPICALGLSQIGRM NLGMDASTFKYYTMCGLQEGFEPFAVNMNRDVAMWFSKRLPTFVNVPKNHPHIEIWRIDG TIESPPRLKVTHKTFGTQNSSSDMIYCRLSMPVEFRSSFNFGMGVENASSDVFQKRKHSQ EVSVPSTTYFYSLRIFAGQDPSCVWVGWVTPDYHFYSENFDLNKNCTVTVTLGDERGRVH ESVKRSNCYMVWGGDITSNSQRSGRSNVDLEIGCFVDLATGMLSFTANGKELGTCYQVEP NTKLFPATFVQPTSTNLVQFELGKLKNTMPLSAAIFKSEERNPVPQCPPRLDVQTITPVL WSRMPNSFLKVETERVSERHGWVVQCLEPLQMMALHIPEENRCVDILELCEQEDLMKFHY HTLKLYSSVCALGNTRVAYALCSHVDVSQLFYTIDNQYLPGLLRSGFYDLLISIHLEHAK QAKLMMNNEFIIPVTEETRTIRLYPDETKKHGLPGVGLSTCLKPGFHFSAPCFIVTSEEH QTSSPEIPLDTLKSKAISMLTEAVQCSGAHIRDPVGGHIAFQFVPVLKLIATLLIMGVFD DDDVKQVLILIDPNVFGDHKEETEEGTEKEEVTQVEEKAVEAGEKAIKETKAPTTGLLQT RLPESVKLQMCHLLNYFCDCELQHRVEAIVSFADRYVSKLQYNQKYRYNELMQALNMSAA LTAKKTKEFRSPPQEQINMLLNFQLGEDCPCPEEIRDELYDFHDDLLIHCGIPLEEEEEE EEDSTLTGKLRSLIYKIKGPPKAEKVEPREEEEKSPTTLKELISQTMVRWSQEDQIQDPE LVRIMYTLLRRQYDSIGELLQALRKAYTISATSVKDTINLLAALGQIRSLLSVRMGKEEE LLMINGLGDIMNNKVFYQHPNLMRVLGMHETVMDVMVNVLGGDKSQIVFPKMVASCCRFL CYFCRISRQNQKAMFEHLSYLLENSSVGLAFPSMRGSTPLDVAAASVMDNNELALALEEP DLDKVVTYLAGCGLQSCPVLLAKGYPDIGWNPIEGERYLSFLRFAVFVNSESVEENASVV VKLLIRRPECFGPDLRGEGGNGLLAAMQEAIRISENPSRDLPSQGYRREGDEEEEEEEIV HMGNAIMSFYSALIDLLGRCAPEMHLIQSGKGEAIRIRSILRSLVPTEDLVGIISIPLKL STVNKDGTVNEPDMSANFCPDHKAPMVLFLDRVYGIKDQSFLLHLLEVGFLPDLRASASL DTVTLSTTEAALALNRYICSAVFPLLKRCAPLFSGTEHHASLVDSMLHTIYRLSKGRSLT KAQRDTIEECLLAICHHLRPSMLQQLLRRLVFDVPLLNEYCKMPLKLLTNHYEQCWKYYC LPSGMGSYGIAAEEELHLTEKLFWGIFDSLSHKKYDPELFRMALPCLSAIAGALPPDYLD TRIRSTLEKQTSVDPEGNFDPKPVSTANLVLPEKLEYIVSKYAEHSHDKWAFDKTNNGWK YGVSLDENTKTHPLIRPFKTLTEKEKEIYRWPARESLKTMLAMGWSLERTKEGGEAILHQ RENEKLRSISQSSQGNGYSPAPLDLSNVVLSRELQGMVEVMAENYHNIWAKKKKMELESK GGGSHPLLVPYDTLTAKEKSRDREKAQELFKFLQVNGIIISRGLNDMDLDASSMEKRFAF KFLKKILKYVDSAQEFIAHLEAIVTSGKTEKSPHDQEIKFFAKVLLPLVDQYFTNHCLYF LSSPTKTLSSSGYASNKEKEMVASLFCKLAALVRHRISIFGSDSTTMVSCLHILAQSLDT RTVMKSGSELVKAGLRAFFENAAEDLEKTSENLKLGKFTHSRTQIKGVSQNINYTTVALL PVLTSIFEHISQYQFGVDLLLGDVQVSCYRILCSLYSLGTGKNIYVERQRPALGECLASL AAAIPVAFLEPSLNHYNPLSVFNTKSARERAILGMPDTVEEMCPEIPQLDGLIKEINDLA ESGARYTEMPHVIEVILPMLCNYLSYWWERGSESVPESAGPFCTMITSEHLSIILGNILK IINNNLGIDEASWMKRIAVYAQPIISKARPDLLKTHFIPTLEKLKKKAIKIVMEEEQLKA DSKTDTQEAELLILDEFAVLCRDLYAFYPMLIRYVDNNRANWLKKPDADSDELFRMVAEV FILWCKSHNFKREEQNFVIQNEINNLAFLTGDTKSKMSKAMQVKSGGQDQERKKSKRRGD LYSIQTSLIVAALKKMLPIGLNMCTPGDQELISLAKTRYSHRDTDEEVKEHLRNNLHLQE KSDDPAVKWQLNLYKDILKSDEPTDPEKNVERVQRISAALYHLEQVEQPLRSKKAVWHKL LSKQRKRAVVACFRMAPLYNLPRHRSINLFLHGYQNYWIETEEYSFEEKLVQDLATPPKK DEEEEEDTEKKQPDPLHQIILYFSRNALTERSKLEDDPLYIAYSAMMAKSCQEEEEEEEE EKEKTFEEKEMEKQRTLYQQARLHDRGAAEMVLQMISASKGHTGPMVVETLKLGIAILNG GNTIVQQKMLDYLKEKKDAGFFQSLSGLMQSCSVLDLNAFERQNKAEGLGMVTEEGTLIV RERGEKVLQHDEFTRDLFRFLQLLCEGHNNDFQNYLRTQMGNTTTVNIIISTVDYLLRLQ ESISDFYWYYSGKDVIDESGQRNFSKALAVTKQIFNSLTEYIQGPCIGNQQSLAHSRLWD AVVGFLHVFANMQMKLSQDSAQIELLKELLDLLKDMVVMLLSLLEGNVVNGTIGKQMVDT LVESSSNVELILKFFDMFLKLKDLTNSDAFKEHDPDGKGIISKKEFQKSMEAQKQYIQSE IEFLLSCAEADENDMFNYVDFVERFHEPAKDIGFNVAVLLTNLSEHMPNDSRLQSLLEPA ESVLNYFEPYLGRIEIMGGAKKIERVYFEISESSRMQWEKPQVKESKRQFIFDVVNEGGE QEKMELFVNFCEDTIFEMQLASQISETDSAERPEEEEEESCYVVDIGDDEEEEKSLESPS AFAMACAAVKKNVTNFFKMVTVKNLRKQYRKVRKMTVKEMVKVFFSFFWILFVGMFQLFF TIVWGIFQILWSTVFGGGLVEGAKNIKVTKILGDMPDPTQFGIHDDVTEAEKAEGAEHGI RAELVQFVKGEKAETDIISDIFGIPTKKEGGSKHGHDAGLGDIAEILGSDIQSSLENTVR KKKGLQLSEIAKEAEAERKVEAEKADMEDGEKQDKAKEVLSEQLEEGKVKKKKRRHGQKI EKPEAVMANFFKALEIYQTKMLHYLARNFYNLRFLALFVAFAINFILLFYKVTEEPLDEV EEDSNLWNTFDEEEEEEGMVFFVLEESTGYMAPALRALAVIHTIISFVCVIGYYCLKVPL VVFKREKEVARKLEFDGLYITEQPSEDDIKGQWDRLVINTPSFPNNYWDKFVKRKVINKY GDLYGAERIAELLGLDKNALDFSPVEESEPEEASLLSWLSSIDTKYHIWKLGVVFTDNSF LYLAWYTTMSILGHYNNFFFAAHLLDIAMGFKTLRTILSSVTHNGKQLVLTVGLLAVVVY LYTVVAFNFFRKFYNKSEDEDEPDMKCDDMMTCYLFHMYVGVRAGGGIGDEIEDPAGDPY EMYRIVFDITFFFFVIVILLAIIQGLIIDAFGELRDQQEQVREDMETKCFICGIGNDYFD TTPHGFETHTLQEHNLANYLFFLMYLINKDETEHTGQESFVWKMYQERCWDFFPAGDCFR KQYEDQLG NT seq 14607 nt NT seq  +upstreamnt  +downstreamnt atggctgaagggggtgaaggaggggaagatgaaatacagttcctacgaactgatgacgaa gtagtacttcagtgtgttgccagcgttcacaaagaacaaaggaagttttgcttggcagct gagggacttgggaatcgcctgtgctttttggaaccaacatcagaagctaaatatgttcct ccggacctttgcatttgtaattttgtacttgaacagtccctgtctgtcagagcccttcaa gaaatgctggccaacacaggggataatgccagtgaaggggctgctcaaggtggtcacaga accctgctatatggtcatgctatactacttcgacattcgttcagtgaaatgtatttgact tgtttaacgtcatcaagatcccagacagataaacttgcatttgatgtgggactgagagaa aatgcagcaggtgaagcatgctggtggacaatacaccctgcatctaaacaaaggtcagaa ggagaaaaagttcgaataggtgatgatcttatcctggtcagtgtgtcttctgaaagatac ctgcatctctccatgtcaaatggaagtattcaggtggatgcctcctttatgcagacgctt tggaatgtacatcctacatgctcaggaagcaatattacagaagggtatcttcttggtggg catgtagtacgttttttccatggccatgatgagtgtttgacaattccatctacagatcag aatgattcacagcagaagaaagtactttatgaaactggaggagctggagttcgagcaagg tctttgtggagagtagaaccgcttcgaataagttggagtggaagtaacatcaaatgggga caacctttccgtcttcgacatattacaacaggaatgtacttggctctgaatgatgatgaa ggacttgtaatgttagacagagaaaagtcagatacaacatctactgccttctgttttaga gcatcaaaggagctaaaagaaaaacaggattccactcttaaacgtgatattgatggaatg ggagtcccagaaataaagtacggtgattcagtctgttttgttcaacatgtggccagtgct ttatggttgacttataaagcgcaggatgctaaatcagcacgtttaggtctcttgaaaaga aaggttatattgcaccaagaaggccatatggatgatggtctaaccttacaaagatgtcag catgaagaatcccaggctgctcgaatcattcgcaatactacaagcttattcagccagttt ttaagtggaaacaacagaacactatcacccatcgccctgcctgttgaggagatggctcag actctgcaagacctgattacttacttccagcctcctgaagaagacttggaacacgaggat aaacaaagcaagcttcggtcactgaaaaacagacaaaatctattcaaagaagagggcatg ctggcactagttttgaattgcattgatcgtttaaatgactccaacagtgcagctcatttt gcagaaattgccagagaagaaaatggtaccacatggaaagaaattttaaatctcctttac aaattgttagctgccctcattcgtggcaacagaaacaattgtactcaattttccagtaac cttgattggctaataagtaaattggacagattagaatcttcctcaggtattttggaagtg ttgcactgtatcttgattgaaagcccagaagctttaaatataatagctgaggagcatata aaatctattatttcattgttggataaacatgggcgcaattacaaggttctcgatgtgctt tgctctctctgtgtctgtaatggagttgcggttcgtgccaatcaaaatttgatctgtgac aatctattgcctagaagagacttactcttgcaaacacgtttgattaatgatgtgacaagc ataaggccgaacatatttttgggtgttgctgagggctctgcacaatacaagaagtggtac tttgaattaataattgatcaggttgatccattcttgacggcagaacccacacatttacga gttggatgggcttctacttcaggttatgctccctatcctggaggaggagaaggatggggt ggcaatggtgttggcgatgacctatactcttacggttttgatggccttcatctgtggtct ggtcgagtacccagggctgtagcatctgtcaatcagcatttgttgtcatctgatgatgtg gttagctgctgcttggatttaggtgtgcccagcatttcattccgcattaatgggcagcct gtacaaggaatgtttgagaacttctgtactgaagggtttttcttccctgttgtaagctta tcagcaggtgtaaaagctcgtttcttattgggtggacgtcatggagagtttaaatttctc cctcctgctggctatgctccctgctatgaagccttgcttccaaaagagaagatgaaactg gaaccagtgaaagaatacaagagagattctgatggagtgagggatttgctgggtacaaca caattcctctcccaagcttcctttatcccttgtcctatagacaccagtcagattgctctt ccttttcatcttgaaaagatcagggacaaactagctgaaaatatccatgaactgtgggga atgaataaaatagaactgggctggacatatggcaagatacgggatgataataaaaggcat catccttgtcttgtagaattctcaaaattacctgagacagagaagaattataatctgcaa atgtcaactgaaactctcaaaacccttttggcccttgggtgtcacattgttcatgctaat ccagcagcagaagaagatcttaaaaaagtcaagcttcctaaaaattacatgatgtcaaat ggatataaacctgcccctcttgatctttctgaagtgaaattgttaccttctcaagaattc ctagttgacaaactagcagaaaatgcacacaacgtctgggcaaaagacagaataaagcaa ggatggacctatggcattcaacaggatcttaagaacaaacgtaatcctcggctagtgcca tatgcattattagatgaacgtactaaaaaatcgaacagagatagcctccgtgaagctgtt agaacatttgcaggctatggttatagtgttgagccacctgaccaagaaatagctgatcaa acaacggaaaaagtcagcattgacaagatacgctttttcagagtcgaacagtcttatgca gtgaagtctggaaagtggtactttgaatttgaagctgtgacaggtggagacatgcgtgtt ggctgggccaggccaggctgtcgacctgacatagaactgggagctgatgaccaagcattt gtttttgaaggaagcaaaggccagcgttggcatcaaggcagtggattctttggacgaagt tggcaaccaggagatgtggttggttgcatgataaacttggatgacaaatcaattatcttt actttgaatggagaattgcttataaccagtaaaggttcagaacttgcgtttgctgacttc ggaatagaaagtggttttgttccaatttgcgcactgggtctgtctcagattggacgtatg aaccttggaatggatgccagtacattcaagtattatacaatgtgtggccttcaagaaggt tttgaaccttttgcagtaaatatgaaccgagatgtcgctatgtggtttagtaaacgctta ccaacatttgtcaatgtgccaaaaaatcatcctcacatagagatatggagaattgatgga accattgagagtccacctcgattaaaagttactcacaaaacatttggcacacagaacagc agttcagacatgatatattgtcgtttgagtatgcctgttgagttccgttcatcattcaac tttggcatgggtgtggaaaatgcctcatctgatgttttccaaaaacgaaaacacagccaa gaagtttctgttccttctactacgtatttttattcattgcggatatttgctgggcaagac ccatcctgtgtctgggttggctgggtaacaccagactatcatttttacagtgaaaatttt gacctaaataaaaattgtacagtgacggttactttaggtgatgagagaggcagggttcat gaaagtgtgaagcgcagtaattgctatatggtttggggaggagatataacttctaattcc cagagatcaggtcgtagcaatgttgatttagaaattggatgctttgttgacctagctact ggaatgttgtcattcacagccaatggaaaagagcttggcacttgttatcaggttgaacca aacacaaaactttttccagcaacttttgtacagcctacgagcactaacttggttcagttt gaacttggtaaattaaagaataccatgcctttatcagcagcaatttttaaaagtgaggaa agaaatcctgttcctcagtgtccccctcgccttgatgtgcaaacaattacacctgtttta tggagcaggatgcctaacagctttcttaaagtagaaactgagcgtgtcagtgaacgtcat ggatgggttgtgcagtgtttggaacctctgcagatgatggcacttcatatcccagaggaa aacagatgcgttgatattttggaactatgtgaacaagaagatttgatgaagtttcactat cacactttaaaactctatagctcagtttgtgctctaggtaacactagagttgcttatgca ctttgtagccatgtggatgtatctcagttattttacacaatagataatcaatatttacct ggactcctacgttctggattctatgacttgttgattagtatacatttggagcatgccaaa caagccaagctcatgatgaacaatgaatttatcattccagttacagaggaaactcgaact attagattatatcccgatgaaacaaagaagcatggtttacctggagtagggcttagcact tgtctgaaaccaggctttcatttttctgctccttgctttattgtgaccagtgaagaacat cagacatccagcccagagataccccttgatacacttaaatccaaagccataagtatgcta acagaggcagtacagtgtagtggtgctcatatacgagaccctgttggaggacacattgca ttccagtttgttcctgttcttaaactaatagcaacactgctcataatgggggtttttgat gatgatgatgtgaagcaggtgttaatcctcattgatccaaatgtatttggagatcacaag gaagaaacagaagaggggacagaaaaggaagaagttacacaagttgaagaaaaagctgta gaagctggagaaaaagcaataaaagaaaccaaagctcctacaacaggcttgttgcagaca agattaccagaatctgttaagcttcagatgtgccatttactcaattatttctgtgactgt gagctgcaacatagagtggaagcaattgtgtcatttgcagaccgttatgtatcaaaatta cagtataatcagaaatacaggtataatgaactcatgcaagccttgaacatgtctgcagct ttgactgccaagaagactaaagaatttcggtctcctccacaagaacagattaatatgttg ctgaattttcaactgggagaggattgtccatgtccagaggagattcgggatgagctgtat gacttccatgatgatcttctaattcactgtggtattccactagaagaggaagaagaggaa gaggaagattccaccttgactggcaaactccgttcgttaatatacaaaatcaaaggtcca ccaaaagcagaaaaagtagagcctagggaagaagaagagaaatcacctactacactgaag gaactcatatcccagactatggtacgctggtctcaggaagatcagattcaagatccagaa ttggttcggattatgtataccctccttcgtaggcaatatgacagcattggtgagctactt caagctctgaggaaagcatacactattagtgctacctctgtgaaggatacaattaatctg cttgctgcactgggccagattcgctcacttctcagtgtcagaatgggaaaagaggaggaa ttgctaatgattaatggattaggggatataatgaacaacaaggtgttttatcagcatcct aacttaatgagagtcttgggcatgcatgagacagttatggatgtgatggtgaatgtgctt ggaggagataagtctcagatcgtttttcctaagatggtggcaagctgttgtcgattccta tgctacttctgtcgaattagtcgtcaaaaccaaaaagccatgtttgagcatcttagttac ttactggaaaacagcagcgttgggctggcatttccttcaatgagaggttcaacaccacta gatgttgcagcagcctccgtaatggacaacaatgagcttgcactagcactggaagagcca gatctggataaagttgttacttatttggctggttgcggcctgcagagttgtccagtattg ctagcgaaaggatatccagacattggatggaatccaatagagggtgaacgttacctgtca ttcttaagatttgcagtttttgttaacagtgaaagtgttgaagaaaatgcaagtgttgtt gtcaagctccttattcgacggccagagtgctttggaccagaccttagaggagaaggagga aatggtttgctggcagctatgcaagaagctatcagaatctcagagaatccttctcgtgac cttccctcacagggatataggagagaaggtgatgaggaggaggaagaggaggagattgtg cacatgggcaatgcaatcatgtcattttactcggctctcatagatttacttggacgctgt gcaccagaaatgcatcttattcaaagtggaaaaggtgaagctattcgaatcaggtcaatc ctccgatctctagtgccaactgaagatttggttggaattataagtataccactaaagctg tcaacagttaacaaagatggcacagtaaatgagccagacatgtctgcaaatttctgtcct gatcataaagcaccaatggtactcttcttggaccgtgtatatggtattaaggaccaaagc ttcctccttcacctattggaagttggatttttaccagatttaagagcttctgcctctctg gatacagttactctaagtaccacagaggcagctctcgcactaaatagatatatttgttca gctgtgtttccgttactcaaaagatgtgctcccctcttttctggaacagagcatcatgct tctctggttgactccatgcttcacacaatatataggttatccaaaggacgttcccttaca aaagcacaacgagacactattgaagaatgcctgcttgctatttgccaccacttacgtccc tctatgctacaacagctgttgagaaggctagtttttgatgtaccgctactcaatgagtac tgtaaaatgcctctcaagcttctgacaaatcactatgaacagtgctggaaatactattgt ctaccttcaggaatgggaagctatggaattgcagcagaagaagaattacatttaactgag aaacttttctggggaatatttgattccttgtctcataagaagtatgatccagagctcttt cgaatggccttgccttgtttaagtgctatagctggtgccttgcctcctgattatttagat acacgaattagatcaactttggaaaagcagacttcagtggatccagaaggaaattttgat cccaaacctgtcagtacagcaaaccttgtacttccggaaaagttggagtatattgtcagc aagtatgctgaacattcccatgataagtgggcctttgataagactaataatggatggaaa tacggtgtttcactggatgaaaatacaaagactcacccattaataagacctttcaaaact ttaactgaaaaggaaaaagaaatttatcgttggcctgctagagaatcactgaaaaccatg ttggccatgggatggagcctagaaaggaccaaagaaggaggagaagcaatattacatcag cgtgaaaatgaaaagctccgtagcatatctcagtcgagccagggaaatggatatagccca gcaccacttgatctctctaatgtggtgctttctagggagcttcagggaatggttgaggta atggcagaaaactaccataatatatgggccaaaaagaagaaaatggagttggaaagcaaa ggtggaggtagtcatcctttattggtaccttatgacacattgacagccaaggagaaatca cgggaccgtgaaaaggcacaggagctgtttaaattccttcaagtgaatggtataatcata tctcggggtctgaatgacatggatttggatgcttcatccatggaaaagaggtttgccttt aagtttctgaagaaaattttaaaatatgttgactctgctcaagagttcattgcacatttg gaagccattgtaaccagtggaaaaactgaaaaatctccacatgaccaagaaataaaattc tttgcgaaagttcttttaccattagttgatcagtactttacaaatcactgcctgtacttc ctgtcttctccaacaaaaacactcagtagcagtggatatgcatcaaataaggaaaaggaa atggtagcaagcctgttctgcaaactagctgctcttgttagacataggatctcaattttt ggtagtgattctacaacaatggttagctgcctgcacatcttagctcagtctcttgacact cgaactgttatgaaatcgggatctgagctagttaaagctggattacgtgccttttttgaa aatgcagctgaagatctggaaaaaacttcagaaaatcttaaacttggaaaatttacccat tcacgaacacaaatcaagggtgtttcacagaatatcaattatactacagtagcattgtta cctgtcttgacatcaatttttgagcatatttcacagtatcagtttggagttgatttactt ttgggtgatgtacaagtttcatgttatagaattctttgtagcctctattcccttgggact gggaagaacatctatgttgaaaggcagcgccctgcacttggtgagtgcttagcatctctt gcggcagccattccggtagcatttcttgaaccttctctcaaccattacaacccattgtct gtcttcaacacaaaaagtgcaagagaaagagcaattttaggtatgcctgatacagtagag gagatgtgtccagagatcccccagttggatggactaataaaggaaattaatgatttagca gagtctggagcaaggtatactgaaatgcctcatgtaattgaggttatcttacccatgcta tgcaactatttgtcctactggtgggaacgagggtccgagagtgttcctgaaagtgctggg cctttctgtacaatgataacatctgaacatctaagcatcattctgggaaacattctgaaa atcattaacaacaatctgggaatagatgaagcatcttggatgaagagaattgcagtttat gctcagcctatcatcagcaaagccagaccagatctgctgaaaactcactttattccaaca cttgagaaattgaagaagaaagctataaagattgtgatggaagaggagcaactgaaagca gacagtaaaactgacacccaggaagctgagctactcattctcgatgaatttgctgttctt tgtagagacctctacgccttctatccaatgttgatacgttatgtagacaacaacagagcc aattggctaaagaaaccagatgcagactctgatgaactcttccgaatggtagctgaagtg tttatcctgtggtgtaaatcacataatttcaaaagagaagaacaaaattttgtgattcag aatgaaatcaacaacttggcatttttaacaggagataccaaaagcaagatgtctaaagcc atgcaagtaaagtctggaggacaagatcaagaaagaaagaagtcaaaacgtagaggggat ttgtactccatacaaacatccttgattgtagctgcacttaaaaagatgcttcctattggc ttgaatatgtgtactcctggagatcaagagctcatctctttggctaagactagatacagc catagggacactgatgaagaagtcaaagaacatttacgtaacaacttacatttgcaggaa aagtctgatgatccagctgtgaaatggcagttaaatctgtataaagacattttgaaaagt gatgagcctactgaccctgagaaaaatgtggaacgtgtgcagaggatatcagctgctctg tatcatctggagcaggttgaacaaccgctgagatcaaagaaagctgtttggcataaactc ctgtcaaaacaacgcaaaagggctgttgttgcttgttttagaatggcaccattgtacaac ctgcccaggcaccgttctattaacctcttcctccatggctatcagaactattggatagaa acagaggaatattcatttgaggagaaactagttcaggatttggctacacctccaaaaaaa gatgaagaagaagaggaagatactgagaaaaaacagcctgatccacttcatcagattatc ctttattttagtcgcaatgctctcacagagaggagcaaactagaagatgatcctttatat atcgcctattctgccatgatggcaaagagctgtcaggaagaagaggaggaagaagaggaa gaaaaagagaagacatttgaggagaaagaaatggaaaagcagagaactctttaccagcaa gctcgcttgcatgatcgtggagctgctgagatggtccttcagatgattagtgcaagcaaa ggtcatacaggacccatggttgttgaaacattaaaacttggtattgctattctaaatggt gggaataccatagttcaacagaaaatgttagactacctgaaggagaaaaaggatgctgga ttctttcaaagtctctctggcttgatgcagtcctgcagtgttcttgacttgaatgcgttt gagagacaaaataaagcagaaggcctgggaatggttactgaagaaggaactctcatcgtt cgtgagcgtggtgaaaaagtgttgcagcatgatgaatttactcgagatctatttagattt ttacaactgctctgtgaagggcataacaatgattttcaaaattacctacgtactcagatg ggcaacaccacaacagtgaatattatcattagtactgttgactatctcttgcgtcttcag gaatcaatcagtgacttttattggtactattcaggaaaagatgtcattgatgaatcagga caacgtaacttctctaaagctttggctgtcaccaaacaaatattcaattcccttacagaa tatattcagggcccttgcataggtaaccaacaaagtctggctcatagtaggctgtgggat gcagttgttggctttcttcatgtctttgccaatatgcagatgaaactttcacaggactct gctcagattgaattgcttaaagaactgctagatctactaaaggatatggtagtcatgctg ttgtcactgcttgaaggtaatgttgtaaacggaacgatcggaaaacaaatggtcgatacg cttgtagaatcatctagcaatgtagaattgattttgaaattttttgacatgttcctcaaa ttaaaagatctaactaactcagatgctttcaaagaacatgacccagatggtaaaggcata atttcaaaaaaggaattccagaagtcaatggaggctcaaaaacaatatatacagtcagag attgaattcctgctatcctgtgcagaagctgatgaaaatgacatgtttaactatgtcgat tttgtggaaagattccatgaaccagccaaagacattggatttaatgtagcagtattgcta acaaacctttcagaacacatgcctaacgattcacgccttcagagtttacttgaacctgca gaaagtgttcttaattactttgaaccataccttggccgtattgaaataatgggtggagcc aagaaaatagaaagagtttactttgaaatcagtgagtccagtagaatgcagtgggagaag ccacaggtgaaggaatccaaaaggcagttcatatttgatgttgtaaatgaaggtggagag caagaaaagatggaactctttgtgaatttctgtgaagacacaatctttgaaatgcagtta gcatcacagatctctgaaactgattcagctgagaggcctgaggaagaggaagaagagtct tgctatgttgtagatattggagatgatgaggaagaagaaaagtccctggaatctccttca gcttttgcaatggcctgtgctgcagtgaagaagaatgttaccaacttttttaaaatggtc actgtgaagaacctaagaaaacagtacaggaaagttagaaagatgacagtaaaagagatg gtgaaagtgtttttctcctttttctggatcctatttgtagggatgttccaactgttcttt actatagtgtggggaattttccagattctttggagcactgtatttgggggtggcctggtt gaaggagccaaaaacattaaagtcactaaaatattaggggacatgcctgacccaacacag tttggaatccatgatgatgttacagaagcagaaaaagctgaaggtgctgagcatggcatt agagctgaacttgtccagtttgtaaagggcgaaaaggcagaaactgacattatctctgat atttttggcattcctaccaaaaaagaaggtggctcaaaacatggtcatgatgctggactt ggggatattgcagaaatacttggttctgatatccagtcttctttggaaaacacagttcgt aagaaaaaaggattacagctatctgaaattgcaaaagaagctgaagcagaaagaaaagtg gaagctgagaaggctgacatggaagatggtgagaaacaagataaagcaaaggaagtactg tctgagcagctggaagagggaaaggtgaagaaaaagaagagaaggcatggacaaaaaatt gagaaacctgaggctgttatggctaacttcttcaaagctttggaaatttatcaaaccaaa atgcttcactacctagcaagaaatttttataacttaaggtttcttgctctatttgttgca tttgctatcaactttattctactattttacaaggtgacagaagagccacttgatgaggta gaggaagactctaatctctggaacacttttgatgaagaggaagaggaggaaggcatggtg tttttcgttttagaagaaagtacaggttacatggcacctgctctcagagcattggcagtt attcataccatcatctcctttgtctgtgtgattggatactattgcttaaaggtccctctg gttgtattcaagagagaaaaggaagtagctaggaagctggaatttgatggattatacata actgaacagccatctgaagatgatattaaaggacaatgggatcgcctggttataaacaca ccgtcctttcctaacaattactgggacaaatttgtaaaacggaaggttattaacaagtac ggagacttatatggagcagagcgcatagcagaacttttgggtttggacaaaaatgccctt gattttagtccagtggaagagagtgaaccagaagaggcatctcttctatcatggttaagc tccattgataccaagtaccacatttggaagctcggtgttgttttcactgataattcattt ttatacttagcttggtacacaactatgtctatccttgggcactacaacaacttcttcttt gctgctcatctgctggatattgctatgggtttcaagactttgcgaaccattctgtcttca gtcactcacaatggcaaacagcttgtgcttactgtaggactcctggctgtagtagtgtat ctttacaccgttgtggcattcaactttttccgcaaattctacaacaaaagtgaagatgaa gatgaaccagacatgaaatgtgatgacatgatgacgtgttacctgttccacatgtatgtg ggtgtaagagctggcggtggcattggggatgaaattgaggatcctgcaggagacccttat gaaatgtatcgaattgtctttgacatcacatttttcttctttgtcattgttatcctactg gccattattcaaggtctgatcattgatgcttttggtgaattaagagaccagcaagaacaa gtgagagaagatatggagaccaaatgttttatttgtggaattggcaacgactattttgac acaaccccacatggctttgaaacacatactttgcaagagcacaacttggcaaactacctg ttctttttaatgtatctcataaacaaggatgaaactgagcatactggccaggaatcattt gtgtggaagatgtaccaagaaagatgttgggattttttcccagcaggagactgcttccgg aaacagtatgaggatcaacttggctaa

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