Actinoplanes friuliensis: AFR_12415 Help Entry AFR_12415         CDS       T02892                                  Name (GenBank) amino acid adenylation protein Organism afs  Actinoplanes friuliensis SSDB OrthologParalogGene clusterGFIT Motif Pfam:  Condensation AMP-binding AMP-binding_C PP-binding PapA_C Motif Other DBs NCBI-ProteinID:  AGZ40769 UniProt:  U5VV71 LinkDB All DBs Position 2680139..2700052 Genome browser AA seq 6637 aa AA seqDB search MPATPDKEHLMSSDQQSRIEALPAHLQQILRQRLSGSAPAAPVAEPIPAAPSGEPLPLSF SQQRLWFLDRFQPGGTEYNSALALRLRGPLDRPALTVALRALMTRHEALRTTFDDVDGTA LQVVNPVPDLDVPLVEASAEGLDGLLYDGYAVPFDLRHGPLFRATLYRLADDEHVLLLAV HHIVTDGWSMGILVADLGTLYTAARTGAPGPLPAPELRYADFACWQRRQATGDAARRHAG YWTGQLAGLAPLELPTDRPRPAVRTSHGAVHRFTVPAAVAARLSTLARAHDTTLFTVLTA ACALLFSRYAGQDDVALGTVVSGRNRPELERLVGFFVNTVVLRARVDERHTFAGLLTHVR ETALDAFAHDDVAFERLVEAAGAVRDPSRNPLFDVMVLLHDQRRAAPQLAGLQVEEIELS RRAATVDVSVEFERQDEHLAGFVEYNTDLFDTATAERLTGHLLALLDAVSARPDQRLATV SMLGAGERDRVLTEWNATAADVPPGTFAELYEAQADRTPDATALVARDATLTYRQLDERA NRLARLLADRGAGPERLVALALPRTADMIVALLAVAKAGAVYLPLDPDLPAERIAFVLDD AAPVLILTAGGVVPAGDTPHVALDDPRIVAELAGRPAARPAGAGTRPDHAAYVIYTSGST GRPKGVVVEHRQLVNLFHHHRHGLAAAVGRPMRVTLTAAFSFDTSWEGPLLMADGHELHV VDEQTRLDPHALVGYVRRHRIDFLDLTPSYLRHLLSVGLLADDAHRPAVLMLGGEAIGES LWRELGEVPGTTAYNFYGPTECTVDALSAEVRPGVRPVVGRPLRNVRAYVLDEARQPVPV GIAGELYLAGAQVARGYLHRPGLTAERFVADPYGAPGERMYRTGDRARWTPDGQLDYLGR TDDQVKVRGFRIEPGEIETALLSTPGVAEAVVIARDDDAGHRRLVGYVVPAGSDTVDDAG LRAALRRSLPDYMVPAVFVTLDRLPTTSTGKIDRRALPAPAAPTGEQAAFTAARTEVEQH LAAIWAEVLGAERVGITDNFFALGGDSILSIQVVSRARQAGLRLTSRDIFLHQCIADLAP AVEAATAPADTPLITGPAPLTPIQRWFFDTYGPLPHFTMSMVLELAADVDENRLGAALDA LTRHHEGLRLACTADAQQPVAGHAVLHRHDGLEEAAAALRAALDPATGRMFGAALVRPDD DPAPRLLLVAHHLVVDGVSWRILLEDLETAYCQLGDGQPVALPPVTTPFTQWAHRLAGHV TAGGLDEALDHWTAAGAPPPLPVDHHGTADGHSTRTITVRLGRDDTTALLHRVPPAYRTQ VNDVLLGALGRVLADWTGHDRVAITCEGHGREELLDGVDLSRTVGWFTTQFPVTLQLPAA GDWGRTLLAVKEQLRAVPHRGLSYEALRYLSPAATALSGRPLPQVCFNYHGRWDAGAATG LIRARHDGVGPELDLDRAPAYLLDVVGLVEDGELRLSWLYSDQAHDEATVRRLADAMVEA LQAVVAHCTAPGAGGRSPADFPLAGLDQAGVDRVAGDGRAVEDVYPLTPLQAGMVFHSLV DAGAGLYADRTRLRLGGVTDPTVLAAAWQRVVDRTPALRTTVVWEGVDHPVQVVHREVTL PVSIHDWRALDEAARDDALATLIADDERAGLDLTAVPLMRLAVARTADDEVLVVWTSHHV LLDGWSVGQVFAEVAAEYTAHVRGTATRPVHRRPFRDYLAWLADQDLGQAEQYWRAVLAG MTEPTPLPYDRQPGEVHRSESAETVRVRLSDTESTALRRTAQQHGLTVNTVVQGAWALLL ARCGGGPDVVFGTTVSGRPAELTGVESMIGMFINTVPTRVSVLRDEPAADWLRGLQQAQS EARRFDWTALSRLRGWSDLPAGDNLFDSVVVFENYPYDEAAVTAGALQLRDVHATDTTNF ALALSAYLADGLRLELAYDPGLFDPGTAQALAARLRLLLNSFAADPRRPVADHAWLLPGE RHRVLTEWNATGLDIPATTWTQAFEEQVRRTPDVLALTCQDTTFTYAALEARANRLAHLM IRAGVGPERVVAVTLPRSADSVVAILAVLKAGGVYLPVDPTLPADRIHLLCRDAGAALVL GAAPGPGGDLPVLRLDDPATTAALAGCPDTAPHDGDRLSPLRPENSAYLIYTSGSTGRPK GVLVEHRQLSTLYFDHRHELIEPESRAAGRPLTVALTAVFSFDTSWEGLLFLAAGHPLHV IDDETRLDPAALVGYITEHRVDLLDLTPTYARQLLPAGLLDDARPYPRVVMLGGEATDPE LWQALAGSRVTGYNYYGPTECAVDSVSCRITDADRPVIGRPGRNQHAYVLDAGLAPVPPG VTGELYIAGDQVARGYLNRPGLTAQRFVADPYTGPGTRMYRTGDLVRWTSEGLLEYLGRA DEQIKIRGHRIEPGEVEAALLAGPELTAAAVVAHESAPGLRRLVAYLVAAPGATLPVAAD LRTHLARTLPEQLIPAAFVEVDRLPMNSSGKLDRRSLPAPDFGDTGGRVHIALRTPAERL VARVWSEVLAVPVIGAGDNFFELGGDSILSMRVTARLRELSGVRISPRAVFTTPTPAGLA SVLDAGAAVPAGGVIPRADRSRPLPLSFAQQRLWFLDQFEPGGTEYVSPLALQLTGDLDT GALEAALTALVDRHESLRTTFRTGADGLAEQLIHPPAPVHLDRVDLTGADPEAVDRALAE HTGRPFDLAAGPLLRVLLARTGAQQHVLLLVLHHIITDGWSGGLLTDELGELYAAALHGT PARLPELPLTYADFAVWQRARLTGPAVDGQLGYWRDRLAGITPLDLPTDRPRPAVRTSAG AAHAFTVPAELTARLHSLGRAHDCTLFTTLVAACQLLLSRWSGQDDITVGTVTSGREHPG LERIVGFFVNTVVLRSAVDPRTPFHALLRRVRETVLGAFAHQDVPFERLVDELQPVRDTS RNPLFDVLVVLQNLPAEPPALTGLSAEELPPPVLTATHDLAFEFEERDGVLAGAVEYNTD LFDAATVARLTAHLVTLLAAVVDAPGRPVGAAALLTAGERHEVTALHCGPPADVPATPFP ELVAAQAVRTPDATAVVAGTDTLTYAELLNRADRLAARLRSRGCGPEQVVAVALPRRIDL VIAFLAVLRAGAVYLPIDPDQPAARTAVVLHDAAPVLVITAGALAGVPAGTGTLDLTVAA ALDDTPPQHFTPPGPEHAAYIIYTSGSTGRPKGVTVEHRQLTNLAAHQRAGFLADFAAAH GDRPLRAALAAAATFDASLEELLLLAGGHEVHVLDDTVRLDAEAFTGYVAEHRIDLVDVT PSYARTLLPAGLLDDRRHRPHIMLLGGEAIGAPLWTALSRVPDLLAYNMYGPTECTVDSL AGRISGDGRPVLGRPLTNLRAYVLDQRLEPVPVGVPGELYLAGPQVARGYLHHPGRTAAQ FPADPYGPPGERMYRTGDRARWTAEGTCEFLGRADEQLKIRGFRVEPGEVEAALTGHPDV TEAVVAGHTGQDGHQRLVGYLVTTGGRDPDDAGLRAWIKRTLPGYLVPAVFVVVDRLPLT PAGKVDRRALPEPPLPGGDRTDFVAPRTDIEQSLAGIWADVLGAARVGVTDNFFALGGDS ILSIQVVSRARQAGLRVSSKDIFLHQTVADLATVVTTSRPAAATAAAMTGPAPLTPIQHW FLGHETEHRDHFAMSMLVDVPADVDRRILGAALDAVVAHHQALRMRFSHGPAGWTQQPAD AAGGSLTVHDLSDLAADDLEAALDRHALDAQRGLGITAGPLLRAVLFELGADRPPRLLLV VHHLVIDGVSWRILLDDLETVYRRLTDGRPAEPAPVGTEYTAWAHRLAGLVAAGGLDDAV PYWTRTVAETAANLPVDRDGANTTATTRSVTVELSPADTDALLHRVPPVYRTQANDVLLS ALGRVLGGWTGRDRILIALEGHGREELFEDVDTSRTVGWFTAEFPVALTVPAGDWAAVLT GVKEQLRAVPHRGLSYGALRHLSAPDAPGAALHGTPVPQLSFNYHGRWDVDAEPDGLIRA AHPGVGQDVAPDSNRPYLIEITGAVTDGRLQLEWAYSEQRHDEATIRRLAEAMTDALREI VEHCARPGAGGRTPSDFPLAGLDQAAVDRLAGDGRDVEDIYPLTPLQAGMLFHSLVDGDS GAYLDQVQVRISGVTDPAALAEAWQRVADRTPALRSAVAWEGLTRPVQVVRRHVTVPVTL LDRRSWPADDLPAELDRLAEADRAITMAVTTAPLLRLAIIRLPGDEVLLRWSSHHLILDG WSTAAVFAEVSEQYAGLTTGREPRLTPRRPFRDYLAWLQEQDPADTRRYWREVLAGVEAP TPLPYDRPPTGTHRTESTAAVRVELTAAESALLHATARTAGLTVNTVVQGAWALLLAHHS GERDVLFGTTVSGRPADLPGVESMIGMFINTLPTRTRIDDRADLVGWLRELQLQQSEARR YGHASLVDLRGCSDLPPGGHGLFDSMVAFENYPIDADPAHDGGLQIGAVDGIDTTTFALS LTAYLDDQLRFELAYDPGLFDAVTAAALTDRLCILLRAVADDPHRTLDRLPWLPGDTVSQ VLTGFNTTSRPLEPATLTRLLRDQTARTPDAPAVVFEGERLTYAELDARARDLAARLVAA GAGPETCVAVALPRSTELIVALVAVLHAGAAYLPIEPGLPADRVAFMLADARPVLTLDTT TELPAPAAGPLPEPVPGNPAYVIYTSGSTGRPKGVTVPHEGIVNRLLWMQHEYALGAGDV VLQKTPAGFDVSVWEFFWPLTVGATLVVARPDGHRDPGYLAAVIQEQAVTTVHFVPSMLR AFVAEPAATGCTSLRRVICSGEALPGDLVADFQRVLDAGLHNLYGPTEASVDVTAYACPP GWTAATVPIGRPVWNTRTYVLDRRLRPVPPGVPGELYLAGVQLARGYLHRPGLTAQRFPA DPYGRPGERMYRTGDLARWTADGRLEYLGRTDHQIKINGQRVEPGEIEAALAAHPALREV AVVARDDGPGGARLVGYLVPADDDIPDTAALRAWLRRGLPEHMVPAAFVTLDRLPLTTSG KLDRRALPAPGPDTRTGPGFLAPRTETERIVAAIWAELLKVDRVGAADDFFALGGDSILS IGLTSRLREAFGTQLSPRAVFDHPTVAGLAVALTGAPGTDGIPVRPRDRALPLSFAQQRL WFLHQFEPDSAEYVTPVALRLTGPLDTGALDAALTALTARHESLRTTFRTGADGVAEQVI HPPLPAPAEQQPVTPETLDAVLAELVGRPFDLAAGPLLRPTLLRLAAEDHVLLLVQHHII TDGWSTGVLIAELAELYTAHVTGAPAHLPTLPVQYADFAAWQRDRLTGPLLDDQLAFWRE TLAGVDTLELPTDRPRPPVHSTHGAVHELRIPPALAARLTALGRTHGGTLFTTLVAACQV LLSRWSGQDDIAVGTVTSGRDRAELADLVGFFVNTLVLRTAVDGRRTFAELLDDVRHTVL GALAHQDVPFERLVDELRPARDPSRTPLFQVMVVLQNLPGAAPELPGLRAEPVELELTTA GYDLTMEFEDSADGLGVSLTYNTDLFDAATIGRLATHLTSLFEAVVADPDQPVSRLPLLG DDERRHLLTGLNDTGRTVPPATLDELFAAQAARTPDAPAVRHPGGELTYAELDEQVDRLA RLLIGRGAGPESIVALLLPRSADIVVAQLAAGRAGAAYLPVDPGYPAGRIAFMLEDARPV LTVTRTGLAGGVPAGTELVLLDDPAVTAALATGTPRVTDTDRRAPLRPEHPAYVIYTSGS TGRPKGVTVTHAGVAGFSAAEIAHFAVAPGDRVLQFASPSFDASVLELCMALPAGATLVV PPPGPLVGEHLGAVLAGERVTHTLIPPAALATVPEIELPDLATLIVGGDACDAALVARWA PGRRMINAYGPTESTVVTSWTGPLSPGGVPAIGRPILNTRVYVLDRHLQPVPLGVAGELY VAGVGLARGYLRRTGLTAQRFIADPYGASGTRMYRTGDVARWTAAGELEFLGRADDQVKI RGFRIELGEVQAALTAHPEVAQAVVTAREDQPGIKRLVAYVVPPSGTAAPATTQLREFLG RTLPDYLVPAVFVPLTALPVTANGKVDRAALPAPDPAAGAAPGAGHVSPRTPVEQTLAGI WADVLGLDRVGVHDNFFDAGGDSILSIQVVSRTRQAGLHLTTKDLFRHQDIASLAGVVTV VAADDAAHAPVVGEVQLTPIQQWFFDTHTANPHHFNQAVMLELPAEVDDVALNEALTTLV AQHDALRSVFTRTPDGWRQEIMPVRPVAVLRHHRLPDTGDAQQQAALEKVADDVHASFDL HRGGLFQAVLFDRGTGQRPYLLLVAHHLVVDGVSWRILLDDLDTAYRQLRGGDPADLGAR TTSVRDWAARLAGHVTSGALDGEVEYWAAAGPATAAPLSPPTPSDDPPVPMGTVSVTLDA DDTETLLRSAPGAYRTRINDVLLAGLAWALSGRTGSGRVLVQLEGHGREDILDGVDLSRT VGWFTTVYPVALDVPAGPEPHWRTLIKSIRRQLRAVPGNGLGHGALRYLGDDRTRERLSG SPGPEVVFNYLGQWDARPQEAQDTLYVAAHPAPGQDHDPRDRQSQALEVVGSVHGGELEF SWYFQPGRHDHDQVSAVAEAFAAALRAIAVDCRQGRA NT seq 19914 nt NT seq  +upstreamnt  +downstreamnt atgccggcgacccccgacaaggagcacctgatgtcgtctgaccagcagagccgcatcgaa gcgctacccgcccacctgcagcagatcctccgccagcgcctgagcggctcagcgccggcc gccccggtcgccgagccgatcccggccgcaccgtccggcgagccgctgccgctgtcgttc tcccagcagcggctgtggttcctggaccgcttccagcccggcggcaccgagtacaacagc gccctggccctgcgcctgcgcgggccactggaccggccggcgctcaccgtcgcactgcgc gccctgatgacccggcacgaggcgctgcgcaccaccttcgacgacgtcgacgggaccgcg ctgcaagtggtcaacccggtgcccgacctcgacgtgccgctggtcgaggcgtccgccgaa ggactggacgggctgctgtacgacggctacgccgtcccgttcgacctgcggcacggcccc ctgttccgggccaccctgtaccggctcgccgacgacgagcacgtgctcctgctggccgtg caccacatcgtcaccgacggctggtcgatgggcatcctggtcgccgacctcggcacgctg tacaccgcggcccgcaccggcgcaccgggcccgctgcccgctccggagctgcgctacgcc gacttcgcctgctggcaacgccgccaggccaccggcgacgcggcccggcggcacgccggc tactggaccggtcagctcgccggcctggctccgctggaactgcccaccgaccggccgcgg ccggcggtacggacctcacacggcgccgtgcaccggttcaccgtgcccgccgccgtcgcc gcccgcctgagcacgctggcccgggcgcacgacaccaccctgttcaccgtcctgaccgcc gcctgcgcgctgctcttctcccggtacgcaggccaggacgacgtggcgctgggcaccgtg gtctccggtcgcaaccgccccgagctcgaacgcctcgtcggttttttcgtcaacaccgtc gtcctgcgcgcccgggtcgacgagcgccacaccttcgccggtctgctgacccacgtccgg gagaccgccctggacgccttcgcccacgacgacgtcgcgttcgaacggctcgtcgaggcc gccggcgccgtccgcgaccccagccgcaacccgctgttcgacgtgatggtgctgctgcac gaccagcggcgggccgccccgcagctggccgggctgcaggtggaggagatcgagctgtcc cgccgcgccgccacggtggacgtctccgtggagttcgaacgccaggacgagcacctggcc ggcttcgtggaatacaacaccgacctgttcgacaccgccaccgccgagcggctgaccggt cacctgctggccctgctcgacgccgtctccgcccgccccgatcaacggctggcgacggtg tccatgctcggtgccggtgaacgcgaccgggtgctcaccgagtggaacgccaccgccgcc gacgtcccgccgggcaccttcgccgagctgtacgaggctcaggccgaccgcaccccggac gccaccgccctggtcgcccgggacgccacgctgacctaccggcagctcgacgagcgggcg aaccggctggcccggctgctcgccgaccgcggcgccggcccggagcggctggtcgctctg gccctgccgcggaccgccgacatgatcgtggctctgctcgccgtggccaaggccggtgcg gtgtatctgccgctcgacccggacctgccggccgagcggatcgccttcgtgctggacgac gccgccccggtgctcatcctgaccgcgggcggcgtcgtcccggccggtgacaccccgcac gtcgctctcgacgacccgcggatcgtcgcggaactcgccggccgacccgccgcccggccg gccggtgccggcacccgaccggaccacgccgcctacgtcatctacacctccggctcgacc ggccgccccaagggcgtggtggtcgagcaccggcagctggtcaacctgttccaccaccac cggcacggcctggccgccgcggtgggccggccgatgcgggtcacgctgacggcggcgttc tccttcgacacctcgtgggagggcccgctgctgatggccgacgggcacgagctgcacgtc gtcgacgagcagacccgcctcgacccgcacgccctggtcggctacgtgcgccggcaccgg atcgacttcctcgacctgacgccgtcgtacctgcggcacctgctcagcgtcgggctgctg gccgacgacgcccaccgcccggccgtgctgatgctcggcggcgaggcgatcggcgagtcc ctctggcgggaactgggcgaggtgcccggcaccaccgcgtacaacttctacggccccacc gagtgcaccgtggacgcgttgtcggccgaggtccgccccggcgtgcggccggtggtcggg cggccgctgcgcaacgtgcgggcgtacgtgctcgacgaggcccggcaaccggtgccggtg gggatcgccggagagctgtacctggccggggcccaggtcgcccggggttacctgcaccgt cccggcctgacggcggagcgcttcgtggccgacccgtacggcgcgccgggggagcggatg taccgcaccggcgaccgggcccggtggacccccgacggccagctcgactacctcggccgc accgacgaccaggtcaaggtccgcggcttccggatcgagcccggcgagatcgagaccgcc ctgctcagcacgcccggcgtcgccgaggcggtcgtcatcgcccgcgacgacgacgccggg caccggcggctggtgggctacgtggtgccggccgggtccgacacggtggacgacgccggg ctgcgtgccgcgctgcgccggtcgctgcccgactacatggtgccggcggtgttcgtcacc ctggaccggctgcccaccacctccaccggaaagatcgaccgccgggcgctgccggccccc gccgccccgaccggcgagcaggccgccttcaccgctgcgcgcaccgaggtcgaacagcac ctggccgccatctgggcggaggtcctcggcgccgaacgggtgggcatcaccgacaacttc ttcgccctcggcggcgattcgatcctcagcatccaggtggtctcccgggcccggcaggcc ggcctgcgcctgacctcgcgcgacatcttcctgcatcagtgcatcgccgacctggcaccc gccgtcgaggccgccacggcaccggcggacaccccgctgatcaccgggccggcgccgctg acccccatccagcgctggttcttcgacacctacggcccgctgccgcatttcaccatgtcg atggtgctcgaactggccgccgacgtggacgagaaccggctgggcgcggccctggacgcc ctgacccgccaccatgagggcctgcgcctggcctgcaccgccgacgcgcagcaaccggtg gccggccacgccgtcctgcaccggcacgacgggctcgaggaggccgccgcggctctgcgg gccgccctcgaccccgccaccgggcggatgttcggcgccgccctggtccgtccggacgac gacccggcgccccggttgctgctggtcgcccaccacctcgtcgtcgacggagtgtcctgg cgcatcctgctcgaggacctggagaccgcctactgccagctcggagacgggcagccggtg gccctgcccccggtgaccacaccgttcacccagtgggcccaccgcctggccgggcacgtc accgccggaggcctagacgaggcgctggaccactggacggcggcgggcgcgccaccgccg ctgccggtcgaccaccacggcaccgccgacggccactccacccgcaccatcaccgtccgg ctgggccgtgacgacaccaccgctctgctgcaccgggtgccaccggcctaccgcacccag gtcaacgacgtgctgctcggcgccctcggccgggtgctggccgactggaccggccacgac cgggtggcgatcacctgcgagggccacggccgcgaggaactgctcgacggcgtcgacctg tcacggaccgtcggctggttcaccacccagttcccggtcaccctgcagctgcccgcggcc ggcgattggggccgcacactgctcgccgtcaaggaacagctgcgcgcggtgccgcaccgc gggctcagctacgaggccctgcggtacctgtccccggccgccaccgccctgtccggccgt cccctgccccaggtctgcttcaactaccacggccgctgggacgccggcgccgccaccggg ctgatccgggcccggcacgacggcgtcggccccgaactcgatttggaccgcgcaccggcg tacctgctggacgtcgtgggcctggtcgaggacggcgagctgcggttgagctggctctac agcgaccaggcgcacgacgaggccaccgtccgccggctggccgacgccatggtggaggcg ttgcaggccgtcgtcgcgcactgcacggcgcccggcgccggcggacgctcgccggccgac ttcccgctcgccgggctcgaccaggcgggcgtggaccgggtggccggcgacggccgcgcc gtcgaggacgtctacccgctgaccccgctgcaggccggcatggtcttccacagcctggtc gacgccggcgccggcctgtacgccgaccgcacccggctgcgcctcggcggcgtcaccgat cccaccgtcctggccgccgcctggcagcgggtcgtcgaccgcaccccggccctgcgcacg accgtggtctgggagggcgtcgaccacccggtccaggtcgtccaccgcgaggtcaccctg ccggtgagcatccacgactggcgggccctggacgaagccgcccgcgacgacgcactggcg acgctgatcgccgacgacgaacgggccgggctggacctgacggccgtcccgctgatgcgc ctggccgtggcccggaccgccgacgacgaggtactggtcgtgtggacctcgcaccacgtg ctgctcgacggctggagcgtcgggcaggtcttcgccgaggtggccgccgagtacaccgcc cacgtgcggggcaccgcgacccggccggtgcaccgccgcccgttccgtgactacctcgcc tggctggccgaccaggacctcggccaggccgagcagtactggcgtgcggtgctcgcgggg atgaccgaaccgaccccgctgccgtacgaccggcagcccggcgaggtccaccgcagcgaa tccgccgagaccgtccgggtccgcctgtccgacaccgaatccacggccctgcgccgcacc gcccagcagcacgggctgaccgtcaacaccgtcgtgcagggcgcctgggcgttgctgctg gcgcgctgcggcggcggacccgacgtggtgttcggcaccaccgtctccgggcgccccgcc gagctcaccggcgtggagtcgatgatcggcatgttcatcaacaccgtcccgacccgggtc agcgtgctccgcgacgaaccggcggccgactggctgcgcgggctgcaacaggcgcagagc gaggcccgccgcttcgactggaccgccctgtcgcggctgcgcggctggagcgacctgccc gccggggacaacctgttcgacagcgtcgtggtcttcgagaactacccgtacgacgaggcg gccgtgaccgccggagcgttgcagctgcgcgacgtgcacgccaccgacaccaccaacttc gccctggccctgagcgcctatctggccgacgggctgcgcctggagctggcctacgacccg gggctgttcgaccccgggaccgcgcaggccctcgccgcccgcctgcgactgctgctgaac tccttcgccgccgacccgcgccggccggtcgccgaccacgcctggctgctgcccggcgaa cgccaccgggtgctgaccgagtggaacgccaccggtctcgacatccccgccaccacctgg acccaggccttcgaggagcaggtccggcggacaccggacgtattggccctgacctgtcag gacaccacgttcacctacgccgccctggaggcccgcgccaaccggctcgcccacctgatg atccgcgccggggtcggtcccgaacgcgtggtcgcggtgaccctgccgcgcagcgccgac agcgtggtcgcgatcctggccgtcctcaaggccggcggcgtctacctgccggtcgatccc acgctgcccgccgaccggatccacctgctgtgccgggacgccggagcggccctggtcctg ggcgccgcaccgggacccggcggcgacctgccggtgctccggctcgacgacccggcgacg accgcggcgctggccggctgcccggacaccgccccccacgacggcgaccggctcagcccg ctgcgaccggagaactccgcctacctgatctacacctccggctccaccgggcggcccaag ggtgtgctggtcgaacaccggcagctgagcacgttgtacttcgaccaccggcacgagctg atcgagccggagagccgcgccgccggccggccgctgaccgtggccctgaccgcggtgttc tccttcgacacgtcctgggaaggcctgctgttcctggccgccgggcacccgctgcacgtc atcgacgacgagacgcgcctggacccggccgcgctggtcggctacatcaccgagcaccgc gtcgacttgctcgacctcaccccgacctatgcccggcagctgctgccggccggcctgctc gacgacgcccggccgtacccaagggtggtcatgctgggcggcgaggcgaccgatcccgaa ctgtggcaggccctggccggcagccgggtcaccggctacaactactacgggcccaccgag tgcgccgtggactcggtctcctgccggatcaccgacgcggaccggccggtcatcggccgc cccggccgcaaccagcacgcgtacgttctcgacgccggcctggccccggtcccgccgggc gtcaccggcgagctctacatcgccggcgaccaggtggcccgcggctacctgaaccggccc gggctcaccgcgcaacgcttcgtcgccgacccgtacaccgggcccggcacgcgcatgtac cgcaccggcgacctggtccgctggaccagcgaaggcctgctggaatacctcggccgcgcc gacgagcagatcaagatccgcggccaccggatcgagcccggcgaggtcgaggcggcgctg ctggccggccctgagctgaccgctgccgcggtcgtcgcccacgagtccgcacccgggctg cgccggctggtggcctacctggtcgccgcgcccggcgccaccctgccggtcgccgcggac ctgcgcacgcacctggcccggacgctgcccgagcagctgatcccggcggcgttcgtcgag gtcgaccggctgccgatgaacagcagcggcaagctggaccgccggtcgctgcccgcgccg gacttcggtgacaccggtggccgtgtgcacatcgccctccgcactccggccgagcggctg gtcgcccgggtctggtccgaggtgctcgccgtgccggtgatcggcgccggcgacaacttc ttcgagctgggcggcgactcgatcctgagcatgcgcgtcaccgcccggttgcgggagctg tcaggcgtacggatctcaccgcgcgcggtcttcaccaccccgaccccggccgggctcgcc tccgtactcgacgcgggcgccgccgtccccgccggcggcgtcattccccgcgccgaccgc agccggccgctgccgctgtcgttcgcccagcagcgcctgtggttcctcgaccagttcgag ccgggaggcaccgagtacgtcagcccgctggcgctgcaactcaccggcgacctcgacacc ggggcactcgaggcggccctgaccgccctggtggaccggcacgagtcgctgcggaccacc ttccggaccggcgccgacgggctcgccgagcagctgatccacccgccggcgccggtccac ctcgaccgcgtcgacctgaccggcgccgacccggaagccgtggacagggccctggccgaa cacaccggccgaccgttcgacctggccgccggcccgctgctgcgggtgctgctggcccgc accggcgctcagcagcacgtgctgctgctggtgctgcaccacatcatcaccgacggctgg tccggcgggctgctcaccgacgaactcggcgagctgtacgcggccgcactgcacggcacc cccgcccggctgccggagctgccgctgacctacgccgacttcgcggtgtggcaacgagcc cggctcaccggcccggccgtcgacggccagctcggctactggcgcgaccggctggctggg atcaccccgctggacctgccgaccgaccggccccgccccgccgtgcgcacctccgccggt gccgcccacgccttcacggtgccggccgagctcaccgcccggctccacagcctgggccga gcccacgactgcaccctgttcaccactctcgtggccgcctgccagctgctgctgagccgc tggtccggccaggacgacatcaccgtcggcacggtcacctccgggcgggagcaccccggc ctggaacggatcgtcggcttcttcgtcaacacggtcgtgctgcgctcggcagtcgacccg cggacaccgttccacgccctgctgcgccgcgtccgcgagaccgtgctgggtgcgttcgcc caccaggacgtgcccttcgaacggctcgtcgacgagctgcaaccggtccgcgacaccagc cgcaaccccctgttcgacgtgctggtggtgctgcagaacctgcccgccgaaccgcccgcg ctgaccgggctgtccgccgaggaactgccgccaccggtgctcaccgcgacccacgacctg gcgttcgagttcgaggaacgcgacggtgtgctggccggggcggtggaatacaacaccgac ctgttcgacgcggcgaccgtcgcccggctgaccgctcacctggtgacgctgctggccgcc gtcgtggacgcgcccggccggccggtcggtgcggcggcgctgctgaccgccggagaacgc cacgaggtgacggccctccactgcggcccaccggccgacgtgcccgccacaccgttcccg gaactcgtggccgctcaggccgtccgcaccccggacgcgaccgccgtggtcgccgggacc gacacgctgacctacgccgagctgctgaaccgcgccgaccggctggccgcccggctgcgg tcccgcggctgcggcccggaacaggtggtggcggtggccctgccgcgccgcatcgacctg gtgatcgcgttcctggccgtgctgcgcgccggtgcggtgtacctgccgatcgaccccgac cagcccgccgcccgcaccgcagtggtgctgcacgacgccgcgcccgtcctggtgatcacc gcgggtgccctggccggcgtcccggccggaaccggcaccctggacctgaccgtggcggca gccctcgacgacacaccgccgcagcacttcacaccgccagggccggagcacgccgcctac atcatctacacctccggctcgaccggccggcccaagggcgtcaccgtcgagcaccgccag ctgaccaacctggccgcccaccagcgcgccggcttcctcgccgacttcgccgcagcccac ggcgaccgcccgctgcgcgccgcgctcgccgccgcggccaccttcgacgcctcgctggag gaactgctgctgctggccggcggtcatgaggtgcacgtgctcgacgacaccgtgcggctg gacgccgaggccttcaccgggtacgtcgccgagcaccgcatcgacctggtcgacgtgacc ccgtcgtacgcccggacgctgctgccggccggactgctcgacgaccgccggcaccgcccg cacatcatgctcctcggcggcgaggcgatcggtgcaccactgtggaccgccttgagccgc gtccccgatcttctggcctacaacatgtacggcccgaccgagtgcacagtggacagcctg gccggacggatcagtggggacgggcgtccggtcctggggcgcccgctgaccaacctgcgg gcgtacgtgctcgaccagcggctcgagccggtgccggtcggcgtacccggcgagctgtac ctggccggcccgcaggtggcccggggctacctccaccacccgggccgcaccgccgcgcag ttccccgccgacccgtacggtccgccgggggagcggatgtaccgcaccggcgaccgggcc cgctggaccgccgagggcacctgtgagttcctcggccgcgccgacgaacagctcaagatc cgcggattccgggtcgagcccggcgaggtcgaggcggccctgaccggtcaccccgacgtg accgaggcggtcgtggccgggcacaccggccaggacggccaccagcggctggtgggatac ctggtgaccaccggcggtcgtgaccccgacgacgccggactgcgggcctggatcaaacgc acgctgcccggctacctggtccccgcggtgttcgtggtagtggaccggctgccgctgacc ccggccggcaaggtcgaccggcgcgccctgccggagcccccgctgccgggcggcgaccgg accgacttcgtcgcaccgcgcaccgacatcgagcagagcctggccggcatctgggccgac gtgctcggcgccgcgcgggtcggcgtcaccgacaacttcttcgccctcggcggtgactcc atcctgagcatccaggtggtctcccgggcgcggcaggccggcctgcgggtcagctccaag gacatcttcctgcaccagaccgtcgccgacctggccaccgtcgtcaccaccagccggccc gcggccgccaccgcggctgcgatgaccggacccgccccgctgaccccgatccagcactgg ttcctcggccacgagaccgaacaccgtgaccacttcgccatgtccatgctggtcgacgtg cccgccgacgtggaccggcgcatcctgggtgccgcgctcgacgcggtggtggcccaccac caggcgctgcggatgcggttcagccacggacccgccggctggacccagcaacccgccgac gccgccggcggcagtctgaccgtccacgacctgtccgatctcgccgccgacgacctcgag gccgcgctggaccgccacgccctggacgcccagcgcggactcggtatcaccgccgggccc ctgctgcgggcggtgctgttcgaactcggcgccgaccggccaccccggctgttgctggtc gtccaccacctggtgatcgacggcgtgtcctggcgcatcctgctcgacgacctggagacc gtctaccgccggctgaccgacggtcgtccggcagaacccgcgccggtcggcaccgaatac accgcctgggcccaccggctcgccggtctggtcgccgccggcggcctggacgacgccgtg ccctactggacccggacggtcgccgagacggccgcgaacctgccggtcgatcgcgacggc gcgaacaccacggcgaccacccgcagcgtcaccgtcgagctgtccccggccgacaccgac gcgctgctgcaccgggtgccaccggtctaccgcacccaggccaacgacgtgctgctcagc gcgctcggccgggtgctcggcggatggaccggccgggaccggatcctgatcgccctggag ggccacggccgggaggaactgttcgaggacgtggacacctcccgcaccgtcggctggttc accgccgagttcccggtcgcgctgaccgtcccggccggtgactgggccgccgtgctgacc ggcgtcaaggaacaactgcgggcggtgccgcaccgcgggctcagctacggcgccctgcgc cacctgagcgccccggacgcgccgggtgcggccctgcacggcacacccgtgccccagctc agcttcaactaccacggccggtgggacgtggacgccgaaccggacgggctgatccgcgcc gcgcaccccggcgtaggccaggacgtcgccccggacagcaaccgcccctacctgatcgag atcaccggcgcggtcaccgacgggcggctccagctcgagtgggcgtactccgagcagcgc cacgacgaggccaccatccgccgcctcgccgaagccatgacggacgcgctacgggagatc gtcgagcactgcgcccggcccggcgccgggggccgtaccccctcggacttcccgctggcc ggcctggaccaggccgcggtggaccggctggccggcgacggccgcgacgtcgaggacatc tacccgctcaccccgctgcaggccggcatgctgttccacagcctggtcgacggcgacagc ggcgcctacctggatcaggtccaggtgcggatctccggcgtcaccgacccggccgccctc gccgaggcgtggcagcgggtcgccgaccgcacccccgcactgcgcagcgccgtcgcctgg gaaggactcacccggccggtgcaggtggtccggcgccacgtcacggtgccggtcaccctg ctcgaccggcgctcgtggcccgccgacgacctgccggccgagctggaccggctcgccgag gcggaccgcgccatcacgatggcggtgaccacggcaccgctgctgcgcctggcgatcatc cggctccccggcgacgaggtgctgctgcgctggagctcgcaccacctcatcctggacggc tggagcaccgctgccgtcttcgccgaggtcagcgagcagtacgccggcctgaccaccggc cgggaaccgcggctcaccccgcgccggccgttccgcgactacctggcctggctgcaggag caggacccggccgacacgcggcgctactggcgcgaagtgctggccggcgtcgaggcgccg acgccgctgccctacgaccggccgccgacgggcacgcaccgcaccgaatcgaccgccgcc gtccgggtggaactgacggccgcggaatcggcgctgctgcacgccaccgcccgcaccgcc ggactgaccgtcaacaccgtcgtgcagggcgcctgggccttgctgctggcccaccacagc ggtgaacgcgacgtgctgttcggcacgaccgtctccggccgcccggccgacctgcccggt gtcgagtcgatgatcggcatgttcatcaacaccctgcccacccggacccgcatcgacgac cgggccgatctggtcggctggctgcgggagctgcaactgcagcagagcgaggcccgccgg tacggccacgcgtcgctggtcgacctccgcggctgcagcgacctgcccccgggcggccac gggctgttcgacagcatggtggccttcgagaactacccgatcgacgccgacccggcccac gacggcggcctgcagatcggcgcggtcgacggcatcgacaccaccaccttcgccctgagc ctgaccgcctacctcgacgaccagctgcgcttcgaactggcctacgaccccgggctgttc gacgccgtcaccgcggccgcgctcaccgaccggctgtgcatcctgctgcgcgctgtcgcc gacgatccgcaccgcaccctcgaccggctgccctggctgcccggcgacacggtcagccag gtactgaccggcttcaacaccaccagccgtccgctggagccggccaccctgacccggctc ctgcgcgaccagaccgcccgtacccccgacgccccggccgtggtcttcgaaggcgagcgg ctcacctacgccgagctggacgcacgcgcccgggacctggccgcccggctggtcgccgcc ggcgccgggccggagacctgcgtcgcggtggcgctgccgcgctcgacggagctgatcgtc gccctggtcgccgtgctgcacgcgggcgcggcgtacctgccgatcgagccaggcctgccc gccgaccgggtcgcgttcatgctggccgacgcccggccggtgctgacgctcgacacgacg accgagctgcccgcaccggcggccggaccgctgcccgaaccggtgcccggcaaccccgcg tacgtcatctacacctccggctcgaccgggcggcccaagggcgtgacggtgccgcacgag ggcatcgtcaaccggctgctctggatgcagcacgagtacgccctcggcgccggcgacgtg gtgctgcagaagaccccggccgggttcgacgtgtcggtgtgggagttcttctggccgctg accgtcggcgccaccctggtggtggcccgcccggacggccaccgtgaccccggctacctg gccgcggtcatccaggagcaggccgtcaccacggtccacttcgtaccgtcgatgctgcgc gcgttcgtggccgagcccgcggcgaccggctgcaccagcctgcgccgggtcatctgcagc ggcgaggcgctgcccggggacctggtcgccgacttccaacgggtgctcgacgccggactg cacaacctctacgggcccaccgaggcctccgtcgacgtgaccgcgtacgcctgcccgccc ggctggaccgcggcgacggtgccgatcggccggccggtgtggaacacccgcacctacgtg ctggaccggcggctgcgcccggtgccaccgggcgtccccggcgagctgtacctggccggc gtccagctggcccgcggctacctgcaccgccccggcctgaccgcgcaacgcttcccggcc gacccgtacggccggcccggcgagcggatgtaccgcaccggcgacctcgcccggtggacg gccgacggccggctggaatatctgggccgcaccgaccaccagatcaagatcaacggtcag cgcgtcgaacccggggagatcgaagccgcactggccgcccacccggccctgcgcgaggtg gccgtcgtggcccgcgacgacggccccggcggagcccggctggtcggttacctggtgccc gccgacgacgacatcccggacaccgccgcgctgcgcgcctggctgcggcgcggactcccg gagcacatggtgcccgcggcgttcgtcaccctcgaccggctgccgctgaccaccagcggc aaactcgaccgccgggcgctaccggcacccggcccggacacccggaccggccccggtttc ctcgccccgcgcactgagaccgaacgcatcgtcgccgcgatctgggccgagctgctgaag gtggaccgggtcggcgccgccgacgacttcttcgccctcggcggcgactcgatcctgagc atcggcctgacctcccggctgcgcgaggcgttcggcacgcagctgtcgccccgcgcggtc ttcgatcaccccaccgtcgccgggctggccgtcgcgctgaccggcgcacccggcaccgac ggcatccccgtccggccccgcgaccgcgcgctgccgctgtccttcgcccagcaacggctg tggttcctgcaccagttcgagccggacagcgcggagtacgtcaccccggtggcgctccgc ctgaccggaccgctggacaccggcgcgctcgacgccgcgctcaccgccctgacggcccgc cacgagtcactgcgcaccaccttccggaccggcgcggacggcgtcgccgaacaggtgatc catccgccgctcccggcgccggccgaacagcagccggtcacgccggaaacgctggacgcg gtcctggccgagctcgtcggccgcccgttcgacctggccgccggcccgctgctgcgcccg acgctgctgcgcctggccgccgaggaccacgtgctgctgctggtgcagcaccacatcatc accgacggctggtcgaccggtgtgctgatcgccgagctggccgagctctacaccgcgcat gtcaccggagcgccggcccacctgcccacgctgccggtgcagtacgccgacttcgccgcc tggcagcgtgaccggctcaccgggccgctgctggacgaccagctcgccttctggcgggag accctggccggcgtggacaccctggaactgccgaccgaccggccgcgtccgcccgtgcac agcacgcacggcgcggtccacgagctccggataccgcccgcgctggcggcccgcctcacc gccctggggcgcacgcatgggggcaccctgttcaccacgctggtggccgcgtgccaggtg ctgctcagccgctggtccggtcaggacgacatcgccgtcggcaccgtcacttcgggccgc gaccgggccgaactggccgacctcgtcgggttcttcgtcaacaccctggtactgcgcacc gcggtggacggccgtcgcacctttgccgagctgctcgacgacgtccggcacaccgtcctg ggcgccctggcccaccaggacgtgccgttcgagcggctggtcgacgagctgcgcccggcc cgcgaccccagccgcaccccgctgttccaggtcatggtggtgctgcagaacctgcccggc gcggcgccggagctgcccggcctgcgcgccgaaccggtcgagctggagctgaccacggcc ggctacgacctgacgatggagttcgaggactccgccgacgggctgggcgtgtccctgacc tacaacaccgacctgttcgacgccgccaccatcggccggctggcgacccacctgacctcg ctgttcgaggcggtcgtggccgacccggaccagcccgtctcacggctgccgctgctcggc gacgacgagcggcgtcacctgctgaccggcctcaacgacaccggccggacagtcccgccg gccaccctggacgaactgttcgccgcgcaggccgcccgcaccccggacgccccggccgtc cgccaccccggcggcgagctgacctacgccgagctcgacgaacaggtggaccggctggcc cggttgctcatcgggcgcggcgcgggcccggagtccatcgtcgcgttgctgctgccgcgc tcggccgacatcgtggtcgcccagctcgccgccggccgggccggggcggcctacctgccc gtcgaccccgggtatcccgccgggcggatcgcgttcatgctcgaggacgcccgcccggtg ctcaccgtgacccgcaccggcctggccggcggcgtacccgccggcaccgagctcgtcctc ctggacgaccccgcggtgaccgcggccctggccaccggcacaccccgggtgaccgacacc gaccgccgggcgcccctgcgcccggagcacccggcgtacgtcatctacacctccgggtcc accggccggcccaagggcgtcacggtcacccacgccggcgtggccggcttctccgccgcc gagatcgcccacttcgcggtcgcgcccggcgaccgggtgctgcagttcgcctcgcccagc ttcgacgcctcggtgctggagctctgcatggccctgccggcgggcgcgaccctggtggtg ccgccaccgggacccctggtcggcgaacacctgggcgcggtcctggccggggaacgggtg acgcacacgctgatcccgccggccgccctggccaccgtgccggagatcgagctgcccgac ctcgccacgctgatcgtcggcggtgacgcctgcgacgcggccctggtggcccgctgggcg cccggtcgtcgcatgatcaacgcgtacggcccgaccgagtccacggtggtcaccagctgg accggccccctgtcgccgggcggcgtgccggccatcggccggccgatcctcaacacccgg gtgtacgtgctggaccgccacctgcaacccgtgccgctcggcgtcgccggtgagctgtac gtcgccggtgtcggcctggcccgcggctacctgcgccgcaccggcctgaccgcgcaacgc ttcatcgccgacccgtacggtgcgtcgggcacccggatgtaccgcaccggagacgtggcc cgctggaccgccgccggcgagctggagttcctcggccgggccgacgaccaggtcaagatc cgcggattccggatcgaactgggagaggtgcaggccgcgctgaccgcccaccccgaggtg gcccaggccgtggtgaccgcccgggaggaccagcccgggatcaagcggctggtcgcgtac gtcgtaccaccgagcggcacagccgcgccggccaccacgcagttgcgggagttcctcggg cggactctgccggactacctcgtcccggcggtgttcgtgccgctgacggcgctgccggtc accgccaacggcaaggtggaccgggccgcgctgcccgccccggaccccgccgccggggcc gcaccgggcgccggacacgtcagcccccgcaccccggtcgagcagaccctggccgggatc tgggccgacgtgctcggcctggaccgggtcggcgtgcacgacaacttcttcgacgcgggc ggggactccatcctcagcatccaggtggtgtcccggacccggcaggcgggcctgcacctg acgaccaaggacctcttccggcaccaggacatcgcgtcgctggccggggtcgtcacggtc gtcgccgccgacgacgcggctcacgcgccggtggtgggcgaagtacagctcacgccgatc cagcagtggttcttcgacacccacaccgccaacccccaccacttcaaccaggcggtgatg ctggagctgccggccgaggtcgacgacgtggcgctgaacgaggcgctgaccactctggtc gcgcagcacgacgccctgcggtcggtgttcacccgcacgccggacgggtggcggcaggag atcatgccggtccggccggtcgcggtgctgcgccaccaccggctgcccgacaccggcgac gcccagcagcaggcggcgctggagaaggtcgccgacgacgtgcacgcgtccttcgacctg catcgcggcgggctgttccaggcggtgctgttcgaccgggggaccgggcagcggccgtac ctgctgctggtcgcgcaccacctggtcgtggacggcgtgtcctggcggatcctgctcgac gatctggacaccgcctaccgccagctgcgcggcggcgacccggcggacctgggcgcccgc accacctcggtccgggactgggccgcccggctggccgggcacgtcacctcgggcgcgctc gacggggaggtggagtactgggccgccgccggtcctgccaccgccgcgccgctgtccccg ccgaccccgtccgatgacccgcccgtgccgatgggaaccgtctcggtgacgctcgacgcg gacgacaccgagaccctcctgcgctccgcgcccggtgcgtaccggacccggatcaacgat gtgctgctggccggtctggcctgggcgctgtccggccggaccggctccgggcgggtgctg gtccagctggaggggcacggccgcgaggacatcctcgacggcgtcgacctgtcccgcacc gtcggctggttcaccaccgtctacccggtggcgctcgacgtcccggccggcccggaaccg cactggcggacgctgatcaaatcgatccgcaggcagctgcgagcggttcccggcaacggc ctcggccacggcgccctgcggtacctcggcgacgaccggacccgggagcggctgtccggg tcgcccggacccgaggtggtcttcaactacctcggtcagtgggacgcccgtccccaggag gcgcaggacaccctgtacgtggccgcgcaccccgcgcccggacaggaccacgacccgcgc gaccggcagtcgcaggcgctggaggtcgtcggctcggtgcacggcggcgagctcgagttc tcctggtacttccagcccggccgccacgaccacgaccaggtgtccgcggtcgccgaagcc ttcgccgccgcgttgcgggcgatcgccgtggactgccggcaggggcgggcatga

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