KEGG   Antechinus flavipes (yellow-footed antechinus): 127552159
Entry
127552159         CDS       T08818                                 
Name
(RefSeq) phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN
  KO
K01110  phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN [EC:3.1.3.16 3.1.3.48 3.1.3.67]
Organism
afz  Antechinus flavipes (yellow-footed antechinus)
Pathway
afz00562  Inositol phosphate metabolism
afz01100  Metabolic pathways
afz01521  EGFR tyrosine kinase inhibitor resistance
afz04068  FoxO signaling pathway
afz04070  Phosphatidylinositol signaling system
afz04071  Sphingolipid signaling pathway
afz04115  p53 signaling pathway
afz04140  Autophagy - animal
afz04150  mTOR signaling pathway
afz04151  PI3K-Akt signaling pathway
afz04218  Cellular senescence
afz04510  Focal adhesion
afz04931  Insulin resistance
afz05165  Human papillomavirus infection
afz05166  Human T-cell leukemia virus 1 infection
afz05200  Pathways in cancer
afz05206  MicroRNAs in cancer
afz05208  Chemical carcinogenesis - reactive oxygen species
afz05213  Endometrial cancer
afz05214  Glioma
afz05215  Prostate cancer
afz05218  Melanoma
afz05222  Small cell lung cancer
afz05224  Breast cancer
afz05225  Hepatocellular carcinoma
afz05230  Central carbon metabolism in cancer
afz05235  PD-L1 expression and PD-1 checkpoint pathway in cancer
afz05415  Diabetic cardiomyopathy
Brite
KEGG Orthology (KO) [BR:afz00001]
 09100 Metabolism
  09101 Carbohydrate metabolism
   00562 Inositol phosphate metabolism
    127552159
 09130 Environmental Information Processing
  09132 Signal transduction
   04068 FoxO signaling pathway
    127552159
   04070 Phosphatidylinositol signaling system
    127552159
   04071 Sphingolipid signaling pathway
    127552159
   04151 PI3K-Akt signaling pathway
    127552159
   04150 mTOR signaling pathway
    127552159
 09140 Cellular Processes
  09141 Transport and catabolism
   04140 Autophagy - animal
    127552159
  09143 Cell growth and death
   04115 p53 signaling pathway
    127552159
   04218 Cellular senescence
    127552159
  09144 Cellular community - eukaryotes
   04510 Focal adhesion
    127552159
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    127552159
   05206 MicroRNAs in cancer
    127552159
   05208 Chemical carcinogenesis - reactive oxygen species
    127552159
   05230 Central carbon metabolism in cancer
    127552159
   05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
    127552159
  09162 Cancer: specific types
   05225 Hepatocellular carcinoma
    127552159
   05214 Glioma
    127552159
   05218 Melanoma
    127552159
   05215 Prostate cancer
    127552159
   05213 Endometrial cancer
    127552159
   05224 Breast cancer
    127552159
   05222 Small cell lung cancer
    127552159
  09172 Infectious disease: viral
   05166 Human T-cell leukemia virus 1 infection
    127552159
   05165 Human papillomavirus infection
    127552159
  09166 Cardiovascular disease
   05415 Diabetic cardiomyopathy
    127552159
  09167 Endocrine and metabolic disease
   04931 Insulin resistance
    127552159
  09176 Drug resistance: antineoplastic
   01521 EGFR tyrosine kinase inhibitor resistance
    127552159
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01009 Protein phosphatases and associated proteins [BR:afz01009]
    127552159
Enzymes [BR:afz01000]
 3. Hydrolases
  3.1  Acting on ester bonds
   3.1.3  Phosphoric-monoester hydrolases
    3.1.3.16  protein-serine/threonine phosphatase
     127552159
    3.1.3.48  protein-tyrosine-phosphatase
     127552159
    3.1.3.67  phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase
     127552159
Protein phosphatases and associated proteins [BR:afz01009]
 Protein tyrosine phosphatases (PTPs)
  Class I PTPs (Dual specificity phosphatases)
   Phosphatase and Tensin homologs (PTEN)
    127552159
SSDB
Motif
Pfam: PTEN_C2 DSPc Y_phosphatase PTPlike_phytase Y_phosphatase3 DUF3256
Other DBs
NCBI-GeneID: 127552159
NCBI-ProteinID: XP_051838611
LinkDB
Position
2:674164038..674236967
AA seq 404 aa
MTAIIKEIVSRNKRRYQEDGFDLDLTYIYPNIIAMGFPAERLEGVYRNNIDDVVRFLDSK
HKNHYKIYNLCAERHYDATKFNCRVAQYPFEDHNPPQLELIKPFCEDLDQWLSEDDNHVA
AIHCKAGKGRTGVMICAYLLHRGKFLKAQEALDFYGEVRTRDKKGVTIPSQRRYVYYYSH
LLKHHLDYRPVALLFHKMMFETIPMFSGGTCNPQFVVCQLKVKIYTSPSGPTRREDKYMY
FEFPQPLPVCGDIKVEFFHKQNKMLKKDKMFHFWVNTFFIPGPEENSDKVENGSLCGDQE
IDSIGSAERSDNDKEYLILTLSKNDLDKANKDKANRYFSPNFKVKLFFTKTVEEPANPEA
SSSTSVTPDVSDNEPDHYRYSDTTDSDPENEPFDEDQHTQITKV
NT seq 1215 nt   +upstreamnt  +downstreamnt
atgacagccatcatcaaggagatcgtgagcagaaacaaaaggagataccaagaggatgga
ttcgacttggacttgacctatatttatccaaacatcattgctatggggtttcctgcagaa
agacttgaaggcgtatacaggaacaacatcgatgatgtagtcaggtttttggattcaaaa
cataaaaatcattacaagatatacaatctatgtgctgaaagacattatgatgccaccaaa
tttaactgtagagttgcacagtatccttttgaagaccacaacccaccccagctagagctc
atcaaacccttttgtgaggatctcgaccagtggctaagtgaagatgacaatcatgttgca
gcaattcactgtaaagcaggaaagggacgaactggtgtaatgatttgtgcatatttatta
catcgaggaaagttcttaaaggcacaagaggctctagatttctatggggaagtcaggacc
agagacaaaaagggagtgactattcccagccagaggcgctatgtatattactatagccac
ctgttaaagcaccatttggattacagaccagtggccctgctctttcacaagatgatgttt
gaaacaattccaatgttcagtggtggaacttgcaatcctcagttcgtggtctgccagctg
aaggtaaagatctacacatccccttcagggcccacaaggcgggaagacaagtacatgtat
tttgaattcccccagcctttgcccgtgtgcggtgacattaaggtggaattcttccacaag
cagaacaagatgctcaagaaggacaaaatgtttcacttttgggtaaatacattcttcata
ccaggaccagaggaaaactcagacaaagtagaaaatggaagtctttgtggtgatcaagag
attgatagtattggcagcgccgagcgatcagataatgacaaagaatatctcatactcaca
ttatccaaaaacgatcttgacaaagcgaataaagacaaggccaacagatacttttctcca
aactttaaggtgaagcttttcttcacaaaaactgtagaggagccggcaaacccagaggcc
agcagttccacttcggtcaccccggacgttagtgacaatgaacctgatcattatagatac
tcggacaccactgactctgatccagagaacgagccttttgatgaagatcaacacacacag
atcacaaaagtctga

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