Arcanobacterium haemolyticum: Arch_0346
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Entry
Arch_0346 CDS
T01242
Name
(GenBank) 2-oxoglutarate dehydrogenase, E1 subunit
KO
K01616
multifunctional 2-oxoglutarate metabolism enzyme [EC:
2.2.1.5
4.1.1.71
1.2.4.2
2.3.1.61
]
Organism
ahe
Arcanobacterium haemolyticum
Pathway
ahe00020
Citrate cycle (TCA cycle)
ahe00630
Glyoxylate and dicarboxylate metabolism
ahe00785
Lipoic acid metabolism
ahe01100
Metabolic pathways
ahe01110
Biosynthesis of secondary metabolites
ahe01120
Microbial metabolism in diverse environments
ahe01200
Carbon metabolism
ahe01210
2-Oxocarboxylic acid metabolism
Module
ahe_M00009
Citrate cycle (TCA cycle, Krebs cycle)
ahe_M00011
Citrate cycle, second carbon oxidation, 2-oxoglutarate => oxaloacetate
Brite
KEGG Orthology (KO) [BR:
ahe00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00020 Citrate cycle (TCA cycle)
Arch_0346
00630 Glyoxylate and dicarboxylate metabolism
Arch_0346
09108 Metabolism of cofactors and vitamins
00785 Lipoic acid metabolism
Arch_0346
Enzymes [BR:
ahe01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.4 With a disulfide as acceptor
1.2.4.2 oxoglutarate dehydrogenase (succinyl-transferring)
Arch_0346
2. Transferases
2.2 Transferring aldehyde or ketonic groups
2.2.1 Transketolases and transaldolases
2.2.1.5 2-hydroxy-3-oxoadipate synthase
Arch_0346
2.3 Acyltransferases
2.3.1 Transferring groups other than aminoacyl groups
2.3.1.61 dihydrolipoyllysine-residue succinyltransferase
Arch_0346
4. Lyases
4.1 Carbon-carbon lyases
4.1.1 Carboxy-lyases
4.1.1.71 2-oxoglutarate decarboxylase
Arch_0346
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Gene cluster
GFIT
Motif
Pfam:
E1_dh
2-oxoacid_dh
Transket_pyr
OxoGdeHyase_C
2-oxogl_dehyd_N
SH3BP5
Motif
Other DBs
NCBI-ProteinID:
ADH92101
UniProt:
D7BMF2
LinkDB
All DBs
Position
complement(402592..406308)
Genome browser
AA seq
1238 aa
AA seq
DB search
MASSQSEEFGANQGFIEDLYSSFLQNPQSVGPQWHEMFHAWQAEGREAPSSSLSPSEETQ
EAQRTVHSSHSREATPATNVTRSDLPPQPRSAAQPAVTPYAKKFDLKPKFDDIFTKSDTE
YVQLKGAERGLAKNMDSSLELPTATSVRALPARVMFDNRTVINKYLATTRGGKISFTHLI
AYAMVEALSEMPEMNYSYQVSDAGKPTLVKPSAVNLGIAIDVAKPNGERTLVVPSIKNAE
HMTFSEFLAAYENLVKRGREGALTIEDYQGTTASLTNPGGLGTTHSIPRLMKGQGLIVGV
GSMVYPPAFAGTAEAQLARMSVSKVVHVTSTYDHRVIQGATSGRFLRLMEHKLLGLDGFY
ERIYIALHVPYKPFVWETDVEYDAERELGKPARIAELIHAYRSRGHLIADTDPLSFHIRR
HPDLEIGSYGLTLWDLDRSFPTGGFAHSSHLTLREILDQLRESYCRTVGIEYMHIQDPVQ
RRWFQERIEKPAEPATIDQRRRILTKLNEAEAFETFLQTKYVGQKRFSLEGGESLIPALD
SILEGAAESGLSDVAIGMAHRGRLNVLTNIAGKSYGQVFNEFDGRIDPSSVQGSGDVKYH
LGTEGVYTSPKGDKVGVYLAANPSHLEAADGVLEGIVRGKHDLIGTDGTFYPVLPILIHG
DAALSGQGVVWEVFNLSQLPAYKNGGTIHIVVNNQIGFTTSPSSGRSSRYTTDIAKGLQI
PIFHVNGDDPEAVARMARMAQEFREAFHKDVIVDISCYRRRGHNEGDDPSMTQPVMYSLV
DSKRTTRHIYAEALIGRGDMTAEDVAELESAYHDTLNEALNSVRASEQTRTESEEQASRS
LGKPQSQEDDAGAMIGWQTAVSPDVVARIGAAHVQVPDGFTPHKKIMQLFNKRNTMCSEG
KIDWGFGELLAFGSLLIEGVPVRMSGQDVRRGTFVQRHATVHGEGTGTEWTPLQHLTEDQ
APLAIYDSALSEYSVMAFEYGYSVERPDALVVWEAQFGDFANGAQTVVDEFISSAEQKWN
QRSSVVLMLPHGYEGQGPDHSSARIERYLQLCAENNMIVAQPSTPANHFHMLRRQAYQRP
RKPLIAITPKQLLRRKGATSAVEEFTSGTFQPVIGEHRTDLNVTRVIMCTGRLYYDLVER
RDQNNDTSVAIIRLEQLYPNPVAELKAELDKYPNAELLWVQDEPANQGAWPHLALEMFMP
MGLQVRRVSRPAAASTATGLGKIHQAQAQTLLNEAFAR
NT seq
3717 nt
NT seq
+upstream
nt +downstream
nt
gtggcgtcatctcaatcggaagaatttggagctaaccaaggcttcatcgaggatctctac
tcctcattccttcaaaatccccaaagtgtaggaccgcagtggcacgagatgttccacgca
tggcaagcagaaggacgcgaagccccgtcgtcgtccctttccccatcagaagaaacccaa
gaagcccaacgaaccgtgcattcatcgcactctcgcgaagcaacaccagctaccaacgtg
acccgttcggatcttccgccgcaaccgcgatcggcagcacaaccggcggtcaccccatac
gcaaagaaattcgatctcaaaccaaaattcgatgatatcttcaccaaaagcgacacggaa
tacgtccagctgaaaggcgcagaacgtggcctggcgaaaaatatggattcgtcactggaa
cttccaactgctacgtcggtgcgtgcgctcccagcccgagtcatgtttgataaccgcact
gtcatcaataaataccttgccacaacccgcggcggaaaaatctccttcacacacctgatc
gcctacgcaatggtggaagccctctctgaaatgccggagatgaactactcgtatcaggtg
agtgacgcgggcaagccaacactcgtgaaaccctccgcagtaaacctgggtatcgcaatt
gacgttgccaaaccaaacggtgaacgcacgctcgttgtgccatccatcaaaaacgcggaa
cacatgaccttctctgagttcctggcggcctacgaaaatctggtgaaacgaggccgcgaa
ggcgccctcaccatcgaagattaccaaggcacaacggcttccctcacaaaccccggcggg
ctcggaactacgcactcaatcccgcgccttatgaaaggccaggggctgatcgtaggcgtt
ggatcgatggtttacccacctgcgttcgctggaactgccgaagcgcaactggcgcgcatg
agcgtatcgaaagtcgtacacgtcacttcaacctacgatcaccgcgtgatccagggcgca
acgtccgggcgattcttgcgcctcatggaacacaagctcctgggactcgatggattctac
gaacgcatctacatcgcacttcacgtgccatacaagcctttcgtctgggaaacggacgtg
gagtatgacgccgaacgggaactcggcaaaccagcccgcatcgcagaactcattcacgcg
tatcgttcgcgcgggcacctgatcgcggataccgatccgctttcgttccatatccgccgc
caccccgatctggaaatcggatcgtatggcctcacgctgtgggatcttgatcgatcgttc
ccaacgggcggatttgctcattcgtctcacttgaccttgcgcgaaatccttgaccaactg
cgcgaatcctactgccgcaccgtaggcatcgaatacatgcatattcaagatcccgtgcag
cggcgctggttccaagaacgcatcgaaaagccggccgaaccggcaacaatcgaccagcga
cgccgaatcctcaccaaactcaacgaagccgaagcattcgaaaccttcctacaaactaag
tatgtggggcaaaagcggttctcactagaaggcggcgaatcgttgattccagcgctcgat
tcgatcctagaaggggctgccgaatccgggctttctgacgtggcgatcgggatggctcac
cgcgggcgattgaacgtgttaacgaacattgctgggaaatcttacgggcaggtctttaac
gaattcgacgggcgcatcgatccgtcatccgtgcaaggatctggggacgtcaagtatcac
ctgggaaccgaaggcgtttatacctcacctaagggcgataaagttggtgtttacttggcc
gcgaacccatcgcatttggaagctgccgacggcgtgttggaaggtatcgtgcgcggcaag
cacgatctcataggcacagatggtacgttctatcctgttttgccgattctcattcacggc
gatgctgccctttctggccagggcgtggtgtgggaagtgttcaacctttcacaactgcca
gcctacaagaacggtggaaccatccacatcgtggtgaacaaccagatcggcttcaccacc
tctccatcatccggccgttcttcgcgttacaccaccgatattgccaaaggtctgcagatc
ccgatcttccacgtgaatggcgatgatcccgaagccgtggcgcggatggcgcggatggct
caagaattccgcgaagccttccacaaagacgtgatcgttgacatttcttgttatcgccgg
cgcgggcataacgaaggcgacgatccttcgatgacccagccagtcatgtattctttagtt
gattccaaacgcaccacccgccatatttatgccgaagcgttgatcggccgtggcgatatg
actgccgaagacgttgccgaactcgaatccgcgtaccatgacactctaaatgaggcgctc
aattctgtgcgcgcttccgaacagactcgtaccgaatctgaagaacaggcatcgcgttct
ttgggcaaacctcaatctcaagaagacgacgccggggcgatgattggctggcagactgcc
gtttcgccggatgttgttgcgcgcattggcgctgctcatgttcaggtgccggacgggttt
acgccacacaagaagatcatgcagctgtttaacaaacgcaacacgatgtgttccgaaggg
aagatcgattggggctttggcgaactgctggctttcggttccttgttgatcgaaggcgta
ccagtgcgtatgtctggccaagatgttcgccgtggaacattcgtacaacgccacgctacc
gttcatggcgaaggcacgggtaccgaatggaccccactgcaacacttaaccgaagatcag
gctccactggcaatctacgattccgcgttgtctgaatattctgtgatggcgttcgagtac
gggtattccgtagagcgccctgatgccctggtggtgtgggaagcccagttcggtgatttc
gccaacggcgctcaaaccgtggttgatgaattcatttcttctgcggaacaaaagtggaac
cagcgttcttccgttgttctcatgttgccgcacggatacgaaggccaggggccggatcac
tcgtcggctcgtatcgaacggtatttgcagttgtgcgcagaaaacaacatgatcgtggcc
cagccgtctaccccggcaaaccacttccacatgttgcgccgccaggcctaccagcggcca
cgcaagccactcatcgcaatcacgcctaaacagttgttgcgccgcaagggagcaacatct
gccgtggaagagttcacgtcaggcacgttccagccggtgatcggcgaacaccgcaccgat
ctgaatgtcacgcgcgtcatcatgtgtaccggccgcctctactacgatttggtagaacgg
cgggatcagaacaacgatacgtccgttgccattatccgccttgaacagctctacccgaac
ccagtagccgaactgaaggctgaactcgataagtatccgaacgcagaactgctgtgggta
caagacgaaccagctaaccaaggcgcatggccacaccttgctctggaaatgttcatgccg
atggggttgcaggtacgccgcgtatcccgcccggcagccgcttcaaccgccactggtttg
ggcaagattcaccaggcgcaagcacaaactcttctgaatgaggcgtttgctaggtag
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