Amycolatopsis japonica: AJAP_08300
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Entry
AJAP_08300 CDS
T03225
Name
(GenBank) Putative AIPM/Hcit synthase family transferase
KO
K01649
2-isopropylmalate synthase [EC:
2.3.3.13
]
Organism
aja
Amycolatopsis japonica
Pathway
aja00290
Valine, leucine and isoleucine biosynthesis
aja00620
Pyruvate metabolism
aja01100
Metabolic pathways
aja01110
Biosynthesis of secondary metabolites
aja01210
2-Oxocarboxylic acid metabolism
aja01230
Biosynthesis of amino acids
Module
aja_M00432
Leucine biosynthesis, 2-oxoisovalerate => 2-oxoisocaproate
Brite
KEGG Orthology (KO) [BR:
aja00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00620 Pyruvate metabolism
AJAP_08300
09105 Amino acid metabolism
00290 Valine, leucine and isoleucine biosynthesis
AJAP_08300
Enzymes [BR:
aja01000
]
2. Transferases
2.3 Acyltransferases
2.3.3 Acyl groups converted into alkyl groups on transfer
2.3.3.13 2-isopropylmalate synthase
AJAP_08300
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Gene cluster
GFIT
Motif
Pfam:
HMGL-like
LeuA_dimer
Motif
Other DBs
NCBI-ProteinID:
AIG74567
UniProt:
A0A075UK74
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All DBs
Position
1664151..1665776
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AA seq
541 aa
AA seq
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MTRKEPADTPLGDAFHLYDTTLRDGAQREGISYSVADKLAVARLLDELGVGFIEGGWPGA
LPKDTEFFARAASGELKLRHAALVAFGATRKAGTKAEQDQQVRALLDSQAPVVTLVAKSD
LRHIERALRVDVDEACEMVRDTVAFLVGEGRRVFLDAEHFFDGYAFSPDTALKVLDAGVN
AGADVAVLCDTNGGQLPLGLAETVREVKERTGFRLGIHCQDDTSCAVANSVAAVQAGVTH
VQCTANGYGERAGNADLFAVTGNLVTKLGMEVLPTGGAAELTRVSHALAEIANIAPYTHQ
AYVGASAFAHKAGLHASAIKVDPLLYNHIDPASVGNDMRVLVTEMAGRASLELKGRELGV
DLAGQPEALTSAVKKVKRLESEGWSFEAADASLELLLRREVDGPQSDVLDEPPFELESYR
VVLDHRSDGEVVSEATVKVHVAGQRVIATAEGNGPVHALDAALREALSPHLSWLDSVELA
DYKVRILPGHPGTDAVTRVLVETSDGEREWTTVGVHGNIVEASWLALCDALVHKSLSEGP
A
NT seq
1626 nt
NT seq
+upstream
nt +downstream
nt
gtgacccgcaaggagcccgccgatacaccgctcggcgacgccttccacctgtacgacacg
acgttgcgcgacggtgcgcagcgtgaggggatctcctactccgtcgcggacaaactggcg
gtggcgaggctgctcgacgaactcggggtcgggttcatcgaaggcggatggccgggcgcg
ctgcccaaggacacggaattcttcgcccgtgcggcttcgggcgagctgaaacttcgccat
gccgcgctcgtcgcgttcggcgcgacgcggaaggcgggcaccaaggccgagcaggatcag
caggtgcgggccctgctcgactcgcaggcaccggtggtcacgctcgtggccaaatccgat
ctgcggcacatcgaacgcgcgctgcgggtcgacgtcgacgaagcttgcgagatggtgcgc
gacaccgtcgcgttcctcgtcggtgaaggacgtcgcgtcttccttgacgcggaacacttt
ttcgacggctacgcgttctccccggacaccgcgctgaaggtgctcgacgcgggcgtgaac
gcgggtgccgacgtcgccgtgctgtgcgacaccaacggcgggcaactgccgctcggactc
gcggaaaccgtccgcgaggtcaaggaaaggaccggattccggctcggaatccattgtcag
gacgacacttcctgcgcggtggcgaattccgtcgccgccgtgcaggccggcgtgacgcac
gtccagtgcaccgccaatggttacggcgagcgggcgggtaacgccgatcttttcgccgtg
acagggaatttggtgaccaagctcggtatggaggtgctcccgaccggaggcgccgccgag
ctcacccgggtctcccatgcccttgccgaaatcgcgaacatcgccccctacacccaccag
gcttacgtaggggcgtcggccttcgcccacaaggcgggactgcacgcgagcgcgatcaag
gtggatccgttgctgtacaaccacatcgatccagcttctgtcggcaatgacatgcgggta
ctggtcaccgagatggccggcagggccagcctggagctcaagggacgtgagctcggggtc
gaccttgccggccagcccgaggcgctgacgagcgccgtgaagaaggtgaaacgcctcgaa
tccgaaggctggtccttcgaagccgcggacgcttcactggaactgctgctgcggcgggag
gtcgacggcccgcagagcgacgtcctcgacgaaccgccgttcgaactcgagtcgtaccgg
gtcgtcctcgaccaccggtccgacggcgaggtcgtctccgaggcgacggtgaaggtgcac
gtcgccgggcagcgcgtgatcgcgaccgccgagggcaacgggcccgtgcacgcgctcgac
gccgccctgcgcgaggcgctcagcccgcatctgtcctggttggacagtgtcgagctggcc
gactacaaggtgcggatcctgcccggccatccgggcaccgacgccgtcacccgtgtgctc
gtcgagaccagcgacggcgagcgcgagtggaccaccgtcggcgtgcacggcaacatcgtc
gaggcgagctggctggcgctgtgcgacgcgctcgtgcacaagtccctcagcgagggcccg
gcgtga
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