Actinosynnema mirum: Amir_3197 Help Entry Amir_3197         CDS       T00957                                  Name (GenBank) Acyl transferase   KO K16029   ansamitocin polyketide synthase A Organism ami  Actinosynnema mirum Pathway ami01051   Biosynthesis of ansamycins ami01052   Type I polyketide structures Brite KEGG Orthology (KO) [BR:ami00001]  09100 Metabolism   09109 Metabolism of terpenoids and polyketides    01052 Type I polyketide structures     Amir_3197    01051 Biosynthesis of ansamycins     Amir_3197  09180 Brite Hierarchies   09181 Protein families: metabolism    01008 Polyketide biosynthesis proteins [BR:ami01008]     Amir_3197 Polyketide biosynthesis proteins [BR:ami01008]  Polyketide synthase (PKS)   Modular type I PKS    cis-AT PKS     Ansamitocin PKS      Amir_3197 BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  ketoacyl-synt Acyl_transf_1 KR Ketoacyl-synt_C AMP-binding PKS_DH_N PS-DH PP-binding KAsynt_C_assoc AMP-binding_C ADH_zinc_N_2 Thiolase_N adh_short Epimerase ADH_zinc_N ADH_N Motif Other DBs NCBI-ProteinID:  ACU37108 UniProt:  C6W8K9 LinkDB All DBs Position 3705533..3719260 Genome browser AA seq 4575 aa AA seqDB search MLRSDLIRPLPELLREHAARRGDRVAFRDARRAVTWADLELRTRRLAGHLAARRLLPGDR AVILLGNRVETVECYLALVRAGAVGVPLNPVSTDAELGGLLDDSGARLVLTDAAHADQLA GLRATRPALEVVHVDRDYEALAGVDAPLPAHDALELDDLAWMLYTSGTTGTPKGVLSTQR NCLWSVAACYAPVLGLTPDDRVLWPLPLFHSLSHIAGVLATTAVGATTRVVDGRSPQDVL AALHEERSTVLAGVPTTYHHLVRAAGERGFLAPDLRVGLVGGAITTAELRAAVEQRFGVP LIDAYGSTETCGSITVNWPTGPRVEGSSGLPVPGLAVRLVDPDTGLDAPTGAEGEVWVRG PSVMLGYHNRPEATAAALRDGWYRTGDLATRDESGFHAVTGRIDDVVVRGGEKVHPAEVE AVLRAVPGVADAAVVGRPHDVLGEVPVAFLVPGEGFDPARVLAVCRERLSYHKVPEELYQ IESVPRTASGKITRRVLLDTPARLRARGERGALFRTDWVPLTAAVGAVTAPGSAVTEPGA ETTVGAATDPDAGSPAGAPTAPVPAPGDAPVVLDLRGDDAPALSGRPDLVLTRGAVAVDG GPVRLGQLAAWTAARRAGITAVDTDDDAAVDPVALLAAGEPRLLVRSGVVLVPRLHEVPG SVVGRGALDPRRAVAVTGADSGTAAALARHLRGAHGVRDLLLITGPDGRARAGALRDDLV ASGARVVLAVAGPDALDRALSRAPSPLGALVHTGDGDPEALPYLLGARVELVVCATAFDS AAAEDVVLRRRAAGMPARCLAWGPWEAEAAQARPGLAVLPLRDGLAAFDAALGADEPVVS VLRPDPDLVAGDVPAPLRDLLHVVAAEPEPVRVAELRAGLAGRGERERRRRLLDLVRAET AALRPAEFVVDGHERGFAELGFTSATSVALRNRLTAATGLALPATAAFEHPTPTALAALL HDELFGASQSPEQAPVAPARAVERSGEPIAVVAAGCRLPGGVASPEDLWEVVRSGSDVVS PFPVDRGWDLDALRGACAGGGFLADAALFDAALFGVHPREALAMDPQQRLLLEVAWEVFE RAGIDPRSVAGDGTGVFAGLMGHDYGSRPGLDRQLVEGYLSTGNAGSVASGRIAYAFGLT GPALTVDTACSSSLVAVHLAVQSLRRGECAMALAGGATVMATPADFVEFARQGALAPDGR CKPFSASADGTAWSEGAGLVLLERLSDARRNGRRVLAVVRGSAVNSDGASNGLTAPSGAA QQRVIRAALADAGLSTADVDAVEAHGTGTRLGDPIEARALVATYGRDRGGEPLWLGSLKS NFGHPQGAAGIAGLIKLVQALRHGVLPRTLHVDAPTPEVEWNGVAVLAEQRAWPEVGRPR RAAVSSFGVSGTNAHVVLEQAPAAPAAPAAPERGAVPLPVSAVDAAALRAQARRLADFLA PSDVTAAELAGALRAGRADLGERAVVVADDRAGALAALEALASDEPSPALVTGRADVTGR VVLVFPGQGGQWVGMGARLLDESPVFAELVDECAAAVDPLVDFRVVDVLRGGDLSRVDVV QPVAFVVMVALARLWRSVGVEPDAVLGHSQGEIAAACVAGALSPADAARVVVLRSRAIAA GLDGGGMASIPLPQAEVEELVAGTGVCVAAVNGPGSVVVSGDVDALVARVEGARRLPVGY ASHSPAVDVLREGLLADLAPITPRPAEIPMLSTVTGTWLDGPELDADYWFANLRHPVRFA DAAALLVADGFRAFVEVGAHPVLTAPVQDLLAGAGPSVATGTLRRDDGGLDRFLRSAAEL HVRGVAVDLSPLAPPPVRALDLPTYPFQRARYWLDADPTAASALRHPLLTSATDLAGGED LVCQARLSTARHPWLADHVVRGSAVLPGTCWAELAIRAGDEVGAPALDELLVEAPLVLPE RGAVEVQLRIGAPDAAGRRPLEAHARAEGGAWTRHASGSLAVDRSTPVPLTEWPPTGARE VDLAGFYDSRAAEGYGYGPALRGLRRAWTRDGEVFAEVELPEPLSPDGWGLHPALFDAAL HATGLLPPARVAADEVLLPFSWRGTRLRATGATALRVRLTGTADDHVLRAYDPEGAPVVE VDALRLRPAPATALVGSGALFRVEWVDLDVHGPTPGSESTTPVLDLPDGDARALLGLTLE ALREHDELTVVTRGAAEDPAAAAVWGLLRTAQTERPGRFTLVDLDDDPASRALLPALPAT GEPQVRVRAGRAGAPRLARTRDDGLRLPAAPTWCLTCDGGTFTDLAATPSPAATRPLEPG EVRVGVRAAGVNFRDAAVVLNAVPGQRGLGGEAAGVVLETGPGVTGLAVGDRVLGTFDRD FGAFGPVAITDARLLAPVPPGWGFARAASVPVAFLTALHGLRDLAQVGPGDRVLVHAGAG GVGGAAVRLAALLGAEVFATASPAKWPVLRALGLDDAHLASSRDTGFAERFPAVDVVLNS LTGELVDASLRLLAPGGRFLELGKVDVRDLVRADVAYRAYDLRDAGPDRTAELLAEVLGL FEQGRLEPLPLTVRDIRHAPEALRHVASGGHVGKVVLTVPRPLDPEGTVLVHGGGALGAL TARHLVSAHGARHLLITSRRGPDAPGAAELAADLAELGATTRFERCDAADRDRVAALLAD LGEHPLTAVVHTAGALDDALLADQDAARVDAVLRPKLDGALLLDQLTRDADLAAFVLFSS AAGTLGNAGQANYAAANAALDALATRRRSAGLPATSIAWGHWESASALTAGLTAADLARG ARHGAGSLGTTEALALLDAALASPEPAVLAAALDPRRAAEVPPLLRDLAGPRRAVAAQAV AGADRPLIDVVRAHTATVLGHRDASAVDAHRAFKELGVDSLTAVELRNRLAAATGLALAA TSVFDHPTPALLTAHLLAELGHAPAAGTTAPATAVTADAGEPIAIVSMACRFPGDVSSPE DLWDLVAGGGDALTPFPADRGWDLATLFAPDPDGAGRSHARAGGFLADVAGFDADLFGIS PREAIGTDPQQRLLLEVAWELFERAGIAPDSLRGTDTGVFAGVIAHGYPVLPAHSDQGLE GHRVTGVSGSVVSGRVAYAFGLQGPAMTVDTACSSSLVGVHLAVRALRGGECSLALAGGV TVLSTPDLFVDFSRQRGLAADGRCKAFGAGADGTGFGEGVGLVLLERLSDARRNGHRVLG LVRGSAVNSDGASNGLTAPSGPAQERVIGRALADAGLSAADVDLVEAHGTGTRLGDPIEA RALVATYGRDRGGEPLWLGSVKSNIGHTQAAAGVAGLIKAVQALRHGVLPATLHADEPTP EVEWDGVAVLAERRDWPEVGRPRRAAVSSFGVSGTNAHVVLEQAPEERVPEGRGPEREAP AGADDRDVPGHLPLVLSAHDPVALRATAAALLPVAEHLPLPDLALSLVTGRAALPCRAVL PARDRDQALAALRDLASGATEPAGRDGGSVAFLLSGQGSQRAGTGRLLERRFPVFRDALR EVCALLDRRIVGGPGVRAALDDPGLLADTRYAQAGLFAVQVALVRLLDALGVRPDLLAGH SVGEIAVAHAAGVLSLEDASTLVAARGALMRELPPGVMVAVRAGEDEVRAALVDGVELAA VNGPRATVLTGDEAAVTEVAARLGRATRLRVAHAFHSAAVDAVLPAFADVLARLDFRPPR VPVVATAPGALDAPEYWLGQAREPVRFADAVTDLHRRGATAFVEVGPGGGLAAAAQECLD GHDVLCAPLLHRDRDEDHSLITALGALHARGARVDFAPLLADAGGRTTDLPTYPFQRRRF WLDPAPPTTDAAPLEHPLLTGELEIPGSDTAAFTGRAATGAHPWLADHRLLDAVVVPGTA LLDLVRAAGRQLGLPEVAELVNEVPLVLGDGAALLRVTAAAPGPDGRREVAVHSRPESAG PRSPWTRHVTGQLAPDGGPLAFDLAQWPPPGAQPLPVADHRAAMAATGHGYGPAFLGLRA AWRLDDEVLVEAVLPDEVADDGHTVHPALLDAVLQALSLTGVEDGSQVRVPFSWRSARGA GRAGRAVRASLRPDGDGGVRVRVACPQGRPLLEIASLVSRPVTPDRLRPGVLLRQAWTEV GPPPGAAEPVPLREVGERVPPVVRVDAGHVRDLLPLLQEAVTEPRWESTRLLVTTSGAVG PRAGRAEGAAVWGLVRSAAAEHPGRFVLADLDDRPESAALLPALATGALPEAVLRAGRVL VPGLHRVAAPSTGGTALDPGGTALITGGSGALAALLAEHLVRAHGVRSLVLLSRSGRGPD VPGADVRHVRGDVADRADVVAALAAVPPDRPLTLVAHLAGVLDDGALTSLTPERLDAVLR PKAEGARHLDELTRDRDLAAFVLFSSVAGVLGHAGQANYAAANAHLDGLAHERHALGLPA TALAWGPWTEGMARGRGGGLSPQVALGLFDAALRTGLPALVPLDREPERRVPAPRAATPA PAGPSLADRLRPMPPAERRAHLLELVTAEALGVLGHDDGAALPAGQAFRDAGFDSITAMA LRNRLVRLAGVRLPASVVFDHPTPAATAERLEAELFPAEQLPGPRHGDDFDDMAADELVR RALGGEWPTPLGGPA NT seq 13728 nt NT seq  +upstreamnt  +downstreamnt atgctgcgaagcgacctgatccgtcccctgcccgaactgctgcgcgagcacgcggccagg cgcggagaccgcgtcgccttccgcgacgcgcgacgcgccgtcacgtgggccgacctggag ctccgcacgcgcaggctcgccgggcacctggccgcgcgcaggctgctccccggcgaccgc gccgtgatcctgctgggcaaccgggtggagaccgtcgagtgctacctggcgctcgtgcgg gccggcgcggtgggcgtgccgctgaacccggtgtccaccgacgccgagctgggcggcctg ctcgacgacagcggcgcccggctcgtcctcaccgacgccgcgcacgccgaccagctcgcc gggctccgcgccacccggcccgcgctggaggtcgtgcacgtcgaccgggactacgaggcg ctcgcgggcgtcgacgccccgctgcccgcgcacgacgcgctggagctggacgacctggcc tggatgctctacacctccggcaccaccgggacccccaagggcgtgctgtccacccagcgc aactgcctgtggtcggtggccgcctgctacgcgcccgtgctcggcctgaccccggacgac cgggtgctgtggccgctgccgctgttccacagcctgtcgcacatcgccggtgtgctggcc accaccgccgtcggcgccaccacccgcgtggtggacgggcgctccccgcaggacgtgctg gccgcgctgcacgaggagcgctccacggtgctcgcgggcgtgcccacgacctaccaccac ctggtgcgcgcggccggtgagcgcgggttcctcgcgcccgacctgcgggtcggcctggtc ggcggcgcgatcaccacggccgagctgcgggccgccgtcgagcagcggttcggcgtgccg ctcatcgacgcctacggcagcaccgagacctgcgggtcgatcaccgtgaactggccgacc gggcccagggtcgagggctccagcggcctcccggtgccggggctggcggtgcggctcgtc gacccggacaccggcctggacgcgccgaccggcgcggagggcgaggtgtgggtgcgcggg ccgagcgtcatgctcggctaccacaaccggcccgaggcgacggccgccgcgctgcgcgac ggctggtaccgcaccggcgacctggcgaccagggacgagtccgggttccacgcggtcacc gggcgcatcgacgacgtcgtggtgcgcggcggcgagaaggtccacccggcggaggtggag gcggtgctgcgggccgtgccgggcgtcgcggacgccgccgtggtgggcaggccgcacgac gtgctgggcgaggtcccggtggcgttcctggtgccgggggaggggttcgacccggcgcgg gtgctggcggtgtgccgggagcggctgtcgtaccacaaggtgcccgaggagctgtaccag atcgagtcggtgccgcgcacggcctccgggaagatcacccggcgggtgctgctggacacg cccgcgcggctgcgggcgcgcggcgagcggggggcgctgttccgcaccgactgggtgccg ctgaccgccgcggttggtgcggtgaccgcgcctggttctgcggtgactgagcctggtgcc gagaccacggttggtgcggcgaccgatcccgacgccgggtcgcccgcgggcgcgcccacc gccccggtcccggcgcccggtgacgcgccggtggtgctcgacctgcgcggcgacgacgcg cccgcgctgtccggccgccccgacctggtgctcacccgaggggcggtggccgtcgacggc gggccggtgcggctcgggcagctcgccgcgtggaccgccgcccgccgcgccgggatcacc gcggtcgacaccgacgacgacgccgcggtcgacccggtcgcgctgctcgccgccggtgag ccccggctgctcgtgcgctccggggtcgtgctcgtgccgcgcctgcacgaggtccccggc tccgtcgtcgggcgcggcgcgctcgacccccgccgggccgtcgccgtcaccggcgccgac agcgggaccgccgccgccctggcccggcacctgcgcggcgcgcacggcgtgcgcgacctg ctgctgatcaccggcccggacgggcgggcccgcgcgggcgcgctgcgcgacgacctcgtg gcctcgggcgcgcgggtcgtgctcgccgtcgccggaccggacgcgctcgaccgcgcgctc agccgggcgccgtccccgctgggcgcgctcgtgcacaccggcgacggggacccggaggcc ctgccctacctgctcggcgcgcgggtcgagctggtggtgtgcgcgaccgcgttcgactcg gccgccgccgaggacgtcgtgctgcgccgccgcgccgccgggatgcccgcccggtgcctg gcctggggaccgtgggaggccgaggccgcgcaggcccggccggggctggccgtgctgccc ctgcgggacgggctggccgcgttcgacgccgcgctcggcgccgacgagccggtcgtctcg gtgctgcgccccgaccccgacctggtggccggggacgtgcccgcgccgctgcgcgacctg ctgcacgtggtcgccgccgaacccgagccggtccgggtggccgagctgcgggcgggcctg gccggtcgcggggagcgggagcgcaggaggcggctgctcgacctggtgcgcgccgagacc gcggccctgcgacccgccgagttcgtggtcgacgggcacgagcgcggcttcgccgagctc ggcttcacctccgccacctcggtcgccctgcgcaaccggctcaccgccgcgaccgggctc gcgctgcccgcgaccgccgcgttcgagcaccccaccccgaccgcgctcgccgcgctgctg cacgacgagctgttcggcgcgtcgcagtcccccgagcaggccccggtcgcgcccgcgcgc gccgtcgagcgctcgggcgagccgatcgcggtcgtcgccgccgggtgcaggctgcccggc ggcgtcgcctcgcccgaggacctatgggaggtcgtgcgctccggctcggacgtggtgtcg ccgttcccggtcgaccggggctgggacctggacgcgctgcgcggcgcctgcgcgggcggc gggttcctggccgacgccgccctgttcgacgcggccctgttcggggtgcacccgcgcgag gccctcgccatggacccgcagcagcggctgctgctcgaagtcgcgtgggaggtgttcgag cgcgccgggatcgacccgcgctcggtggcgggtgacgggaccggcgtgttcgccgggctg atgggccacgactacgggtcgcggccggggctggaccggcagctcgtggagggctacctg agcaccggcaacgcgggcagcgtcgcctcagggcggatcgcctacgcgttcgggctcacc gggcccgcgctcaccgtggacaccgcgtgctcgtcgtcgctggtggcggtgcacctggcg gtgcagtcgctgcggcgcggcgagtgcgcgatggcgctggcgggtggcgcgacggtcatg gccacgcccgccgacttcgtcgagttcgcccggcagggcgcgctggccccggacggccgc tgcaagccgttctcggcgtcggcggacgggacggcgtggtccgagggcgcggggctggtg ctgctggagcggctgtcggacgcgcggcgcaacgggcgccgggtgctggccgtggttcgg ggcagcgcggtgaactcggacggggcgtcgaacgggttgaccgcgccgagtggtgcggcg cagcagcgggtgatccgggcggcgctggcggatgccggtctgtccactgcggacgtggac gcggtggaggcgcacgggaccgggacccggttgggcgacccgatcgaggcgcgggcgctg gtcgccacctacgggcgggaccggggtggtgagccgctgtggctcggctcgctgaagtcg aacttcgggcacccccagggcgcggccgggatcgccgggctgatcaagctcgtgcaggcg ctgcggcacggcgtgctgccgcgcaccctgcacgtcgacgcgcccacgcccgaggtcgag tggaacggtgtcgcggtgctggccgagcagcgcgcgtggcccgaggtgggcaggccgcgc agggcggcggtgtcctcgttcggggtcagcggcaccaacgcgcacgtggtcctggagcag gcccccgccgcgcccgccgcgcccgccgcacccgagcgcggggccgtgccgctgccggtg tccgccgtcgacgcggcggcgttgcgcgcccaggcccggcggctcgccgacttcctcgcc ccctccgacgtcacggccgccgagctggcgggcgcgctgcgcgcgggccgggccgacctc ggcgagcgcgccgtcgtggtcgccgacgaccgggcgggcgcgctcgccgcgctggaggca ctggcctcggacgagccctcgcccgccctggtcacggggcgcgcggacgtcaccggccgc gtggtgctcgtgttccccggacagggcggccagtgggtgggcatgggcgcccggctgctc gacgagtccccggtgttcgccgagctggtggacgagtgcgcggcggccgtcgaccccctg gtggacttccgcgtggtcgacgtgctgcgcggcggcgacctgagccgcgtggacgtcgtc cagccggtcgcgttcgtcgtcatggtcgcgctggcccggctgtggcgctcggtcggcgtc gagcccgacgcggtgctcggccactcgcagggcgagatcgccgcagcctgcgtcgcggga gcgctctcgcctgccgacgcggcccgcgtggtggtgctgcgcagccgggccatcgccgcc gggctcgacggcggcggcatggcctcgatcccgctgccgcaggccgaggtcgaggagctg gtcgcgggcaccggggtgtgcgtcgcggcggtcaacggccccggctcggtggtcgtctcc ggcgacgtcgacgcgctggtcgcccgcgtggagggcgcccgcaggcttccggtgggctac gcctcgcactcgcccgccgtggacgtgctgcgcgagggcctgctcgccgacctcgcgccg atcaccccccgaccggccgagatcccgatgctgtccaccgtcacgggcacgtggctggac ggtcccgagctcgacgccgactactggttcgccaacctgcgccaccccgtccgcttcgcc gacgccgccgcgctcctggtcgccgacgggttccgggcgttcgtggaggtcggcgcgcac ccggtgctcaccgcgcccgtccaggacctgctcgcgggcgcgggcccctcggtcgccacc ggcacgctgcgccgcgacgacggcggcctcgaccggttcctgcgctccgccgccgagctg cacgtgcgcggcgtggccgtcgacctctccccgctggcgcccccgccggtccgggcgctc gacctgcccacctacccgttccagcgcgcccgctactggctggacgccgaccccaccgcc gcctccgcgctgcggcacccgctgctcacctccgccaccgacctcgcgggcggcgaggac ctggtgtgccaggcgcggctgagcaccgcgcggcacccgtggctcgccgaccacgtggtg cgcgggtccgccgtcctgcccggcacgtgctgggcggagctggccatccgcgccggcgac gaggtcggcgcgcccgcactggacgagctgctggtggaggcgccgctggtgctgcccgag cgcggcgcggtggaggtgcagctcaggatcggcgccccggacgccgcagggcgcaggccg ctggaggcgcacgcccgcgccgagggcggcgcgtggacccggcacgccagcggctccctc gccgtcgaccggtccaccccggtcccgctgaccgagtggccgccgaccggcgcgcgcgag gtcgacctggccgggttctacgacagccgggccgccgagggctacggctacgggccggcg ctgcgcgggctgcggcgggcctggacccgcgacggcgaggtgttcgccgaggtggagctg cccgaaccgctgagcccggacggctggggcctgcacccggccctgttcgacgccgcgctg cacgccaccggcctgctgcccccggctcgggtcgccgccgacgaggtgctgctgccgttc tcctggcgggggaccaggctgcgcgccaccggggcgaccgcgctgcgcgtgcgcctgacc gggaccgccgacgaccacgtgctgcgcgcctacgaccccgagggcgcgccggtcgtggag gtcgacgccctgcggctgcgcccggccccggccaccgcgctcgtcggctctggcgcgctg ttccgcgtcgagtgggtcgacctggacgtccacgggcccacgccgggctccgagtcgacc acccccgtgctcgacctgcccgacggcgacgcgcgcgccctcctcggcctgaccctggag gccctgcgcgagcacgacgagctgaccgtggtcacgcgcggcgcggccgaggacccggcc gccgccgccgtgtgggggctgctgcgcaccgcccagaccgagcggccgggccgcttcacc ctggtcgacctggacgacgaccccgcctcgcgcgccctgctgcccgccctgcccgccacc ggcgaaccgcaggtccgggtgcgggcggggagggcgggagcgccgcgcctggcgcgcacg cgcgacgacggcctgcggctgcccgccgccccgacctggtgcctgacctgcgacggcggc acgttcaccgacctggccgcgaccccgagcccggccgcgacccgaccgctggaacccggc gaggtccgggtgggcgtgcgcgccgcgggcgtcaacttccgggacgccgccgtcgtgctg aacgccgtgcccggccagcgcgggctcggcggagaggccgcgggcgtggtcctggagacc ggtcccggcgtcaccggcctcgcggtcggcgaccgggtgctcggcacgttcgaccgcgac ttcggcgcgttcggcccggtcgcgatcaccgacgcccgcctgctcgcgcccgtcccgccc ggctgggggttcgcgcgcgccgcgtcggtgccggtcgcgttcctcaccgccctccacggc ctgcgcgacctcgcccaggtcgggccgggcgaccgcgtcctggtgcacgcgggcgcgggc ggcgtcggcggcgcggcggtcaggctggcggcgttgctgggcgcggaggtgttcgccacc gcgtcgcctgccaagtggccggtgctgcgcgcgctcggcctggacgacgcgcacctggcc tcctcccgcgacaccgggttcgccgagcgcttcccggccgtggacgtcgtgctgaactcg ctcaccggcgagctggtggacgcctcgctgcggctgctcgcgccgggcgggcggttcctg gagctgggcaaggtcgacgtgcgcgacctcgtgcgcgccgacgtcgcgtaccgggcctac gacctgcgcgacgcgggcccggaccgcaccgccgaactgctcgccgaggtgctggggctg ttcgagcagggccgccttgagccgctgccgctgaccgtccgcgacatccggcacgccccc gaggcgctgcggcacgtcgcgtccggcgggcacgtcggcaaggtcgtgctcaccgtgccc cgcccgctcgaccccgagggcaccgtcctggtccacggcggtggcgcgctcggcgcgctc accgcccgccacctggtgtccgcgcacggcgcccgccacctgctgatcacctcccggcgc ggccccgacgcgcccggcgccgccgaactggccgccgacctggccgagctcggcgccacc acgcggttcgagcgctgcgacgccgccgaccgcgaccgggtggccgccctgctggccgac ctgggcgagcacccgctgaccgccgtcgtgcacacggcgggcgccctcgacgacgccctg ctcgccgaccaggacgcggcgcgcgtcgacgcggtcctgcgccccaagctcgacggggcg ctgctgctggaccagctgacccgcgacgccgacctcgccgcgttcgtgctgttctcctcc gccgccgggacgctcggcaacgcgggccaggccaactacgccgccgcgaacgccgcgctc gacgcgctggccacccgccgccgctccgccgggctgcccgccacctccatagcctggggc cactgggagagcgccagcgcgctcaccgccgggctcaccgccgccgacctcgcgcgcggg gccaggcacggcgcaggctcgctcggcaccaccgaggcgctggcgctgctggacgccgcg ctggcctccccggaacccgccgtcctcgccgccgcgctcgacccgcgccgcgcagccgag gtcccgccgctgctgcgcgacctcgccgggccgcgccgggcggtcgccgcccaggccgtc gcgggcgcggaccggccgctgatcgacgtggtcagggcgcacaccgcgaccgtgctcggg caccgcgacgcctccgccgtggacgcgcaccgcgcgttcaaggagctgggcgtggactcg ctcacggccgtggagctgcgcaaccggctcgccgccgcgaccggcctcgcgctcgccgcc acctcggtgttcgaccacccgaccccggcgctgctgaccgcgcacctgctcgccgagctc gggcacgcccccgccgccgggaccaccgcgcccgccaccgccgtcaccgccgacgcgggg gagcccatcgcgatcgtgtcgatggcctgccgcttccccggcgacgtgtcctccccggag gacctgtgggacctcgtcgcgggcggcggggacgcgctcaccccgttccccgccgaccgg ggctgggacctggccaccctgttcgcccccgacccggacggggccgggcgcagccacgcc cgcgcgggcgggttcctcgcggacgtcgcgggcttcgacgccgacctgttcggcatcagc ccgcgcgaggccatcggcaccgacccgcagcagcggctgctgctggaggtggcgtgggag ctgttcgagcgcgcgggcatcgcccccgactcgctgcgcggcaccgacaccggcgtgttc gcgggcgtcatcgcgcacggctacccggtgctgcccgcccactccgaccaggggctggag gggcaccgggtcaccggggtgtccgggagcgtggtgtccggccgggtcgcctacgccttc gggctgcagggaccggcgatgaccgtggacaccgcctgctcgtcgtcgctggtgggcgtg cacctggcggtgcgggccctgcgcggcggcgagtgctcgctggcgctggcgggcggtgtg acggtgctgagcacgccggacctgttcgtggacttctcccggcagcgcgggctcgccgcc gacgggcgctgcaaggcgttcggggcgggcgcggacggcaccgggttcggcgagggcgtc ggcttggtgctgctggagcggctctcggacgcgcgccgcaacgggcaccgggtgctgggg ctggtgcgcggcagcgcggtcaactccgacggggcctccaacgggctgaccgcgcccagc ggccccgcgcaggagcgcgtcatcgggcgggcgctcgcggacgccgggctgtcggcggcc gacgtggacctggtggaggcgcacggcaccgggacccggttgggtgacccgatcgaggcg cgggcgctggtcgcgacctacgggcgggaccggggcggggagccgctgtggctcgggtcg gtcaagtccaacatcgggcacacccaggccgccgcgggcgtcgccgggctgatcaaggcg gtgcaggcgctgcggcacggggtgctgcccgcgaccctgcacgcggacgagcccaccccc gaggtcgagtgggacggggtggcggtgctggccgagcggcgggactggcccgaggtgggc aggccgcgcagggcggcggtgtcctcgttcggggtcagcggcaccaacgcgcacgtcgtg ctggagcaggctcccgaggagcgggttccggaaggccgagggcccgagcgcgaggccccc gccggggccgacgaccgggacgtccccggtcacctgccgctcgtcctgtccgcccacgac cccgtcgcgctgcgcgccaccgcagccgcgctcctgcccgtcgccgagcacctcccgctg cccgacctggcgctgtccctggtcaccggccgcgccgccctgccctgccgggcggtgctc cccgcccgcgaccgggaccaggcgctggcggcgctgcgcgacctcgcgtccggcgccacc gagcccgccgggcgggacggcgggagcgtcgcgttcctgctgtccggccagggcagccag cgggccgggaccgggcggctgctggagcggcggttcccggtgttccgcgacgcgctgcgc gaggtgtgcgccctgctggaccggcgcatcgtcggcggccccggcgtgcgcgcggccctg gacgacccggggctgctcgccgacacccgctacgcgcaggccgggctgttcgccgtgcag gtcgcgctggtgcgcctgctcgacgcgctcggcgtccgccccgacctgctcgccgggcac tcggtcggcgagatcgccgtcgcgcacgccgccggggtgctgtccctggaggacgcctcc accctcgtggccgcgcgcggcgccctcatgcgcgagctgccccccggcgtgatggtcgcg gtccgggcgggcgaggacgaggtgcgcgccgcgctggtcgacggggtggagctggccgcc gtcaacggcccccgcgccaccgtgctcaccggcgacgaggccgccgtcaccgaggtcgcc gcccgcctcgggcgcgccacgcgcctgcgggtcgcccacgccttccactcggccgccgtc gacgcggtgctgcccgcgttcgccgacgtgctggcgcgcctcgacttccgcccgccgcgc gtcccggtcgtcgccaccgcgcccggcgcgctcgacgcgccggagtactggctgggccag gcccgcgagccggtgcgcttcgccgacgccgtcaccgacctgcaccggcggggcgcgacc gcgttcgtcgaggtcggccccggcggcgggctggccgccgccgcgcaggagtgcctggac gggcacgacgtgctctgcgcccccctgctgcaccgcgaccgggacgaggaccactccctg atcaccgcgctcggcgcgctgcacgcgaggggcgcgcgcgtcgacttcgccccgctgctg gccgacgcgggcggccggaccaccgacctgcccacctacccgttccagcgccgccgcttc tggctggaccccgccccgcccaccaccgacgccgccccgctggagcacccgctgctcacc ggggagctggagatccccggctcggacaccgccgcgttcaccggccgcgccgccaccggc gcccacccgtggctggccgaccaccggctgctcgacgcggtcgtcgtgcccggcacggcc ctgctggacctggtgcgggcggccggtcggcagctcgggctgcccgaggtcgccgagctg gtcaacgaggtcccgctggtgctcggcgacggggcggcgctgctgcgcgtcaccgccgcc gcgccgggaccggacgggcgccgcgaggtggccgtgcactcccggccggagtcggccggg ccgcgctcgccgtggacccggcacgtcaccggccagctcgcccccgacggggggccgctc gcgttcgacctggcgcagtggccgccgccgggcgcgcagccgctgccggtggccgaccac cgggccgcgatggccgccaccggccacgggtacgggcccgcgttcctggggctgcgcgcc gcttggcggctcgacgacgaggtgctggtggaggcggtgctgcccgacgaggtcgccgac gacgggcacaccgtgcaccccgcgctgctcgacgcggtgctccaggccctctcgctcacc ggcgtcgaggacggctcgcaggtgcgggtgccgttcagctggcgctccgcgcgcggcgcg ggccgggcgggccgcgcggtccgcgcctccctgcggcccgacggcgacggcggcgtccgg gtgcgcgtggcctgcccgcagggccgcccgctgctggagatcgcctcgctggtgtcccga ccggtcacccccgaccggctgcggccgggggtgctgctgcgccaggcgtggacggaggtc ggcccgccgcccggcgccgccgagcccgtgccgctgcgcgaggtcggcgagcgggtgccg ccggtggtgcgggtcgacgccgggcacgtccgcgacctgctgccgctgctccaggaggcg gtgaccgagccacgctgggagtcgacgcggctgctcgtgacgacctcgggcgcggtcggg ccgcgcgccggtcgcgccgagggcgccgcggtgtggggcctggtgcggtcggccgccgcc gagcaccccggccggttcgtcctggccgacctggacgaccggcccgagtccgccgcgctg ctgcccgcgctcgccaccggcgcgctgccggaggcggtgctgcgcgcgggacgcgtgctc gtgccggggctgcaccgggtcgccgcgcccagcaccggcgggaccgcgctcgaccccggc gggaccgcgctgatcaccggcggctccggggcgctggcggcgctgctggccgagcacctg gtgcgcgcgcacggcgtgcgctccctggtgctgctcagccgcagcgggcgcgggccggac gtgccgggcgccgacgtgcggcacgtgcgcggcgacgtcgcggaccgggccgacgtggtc gcggcgctggccgccgtgccgccggaccggccgctgacgctggtggcgcacctggccggg gtgctcgacgacggcgccctcacctcgctgacccccgagcggctggacgcggtgctgcgc cccaaggccgagggcgcccggcacctggacgagctgaccagggaccgggacctggcggcg ttcgtgctgttctcctcggtcgcgggcgtgctcggccacgccgggcaggccaactacgcg gcggccaacgcccacttggacggcctcgcgcacgagcggcacgccctcggcctgcccgcc acggcgctggcctgggggccgtggaccgagggcatggcgcgcggtcgcggcggcgggctc tcgccgcaggtcgcgctcggcctgttcgacgcggccctgcgcaccggcctgcccgcgctc gtcccgctcgaccgcgaacccgagcgccgggtccccgccccgcgcgccgcgacccccgct cccgccgggccgtcgctggccgaccggctgcgcccgatgccgcccgccgagcggcgcgcc cacctgctggagctggtcaccgccgaggcgctgggcgtgctgggccacgacgacggggcc gcgctgcccgccgggcaggcgttccgcgacgccgggttcgactcgatcaccgcgatggcg ctgcgcaaccggctcgtccggctggccggggtgcggctgcccgcgagcgtcgtgttcgac caccccacccccgccgccaccgccgagcgcctggaggccgagctgttcccggccgagcag ctgcccggcccccggcacggcgacgacttcgacgacatggccgccgacgagctggtccgc cgcgcgctcggcggcgagtggccgaccccccttggaggacccgcgtga

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