KEGG   Ailuropoda melanoleuca (giant panda): 100478007
Entry
100478007         CDS       T01329                                 
Symbol
PRKCB
Name
(RefSeq) protein kinase C beta type isoform X2
  KO
K19662  classical protein kinase C beta type [EC:2.7.11.13]
Organism
aml  Ailuropoda melanoleuca (giant panda)
Pathway
aml01521  EGFR tyrosine kinase inhibitor resistance
aml04010  MAPK signaling pathway
aml04012  ErbB signaling pathway
aml04014  Ras signaling pathway
aml04015  Rap1 signaling pathway
aml04020  Calcium signaling pathway
aml04062  Chemokine signaling pathway
aml04064  NF-kappa B signaling pathway
aml04066  HIF-1 signaling pathway
aml04070  Phosphatidylinositol signaling system
aml04071  Sphingolipid signaling pathway
aml04150  mTOR signaling pathway
aml04270  Vascular smooth muscle contraction
aml04310  Wnt signaling pathway
aml04370  VEGF signaling pathway
aml04510  Focal adhesion
aml04540  Gap junction
aml04613  Neutrophil extracellular trap formation
aml04650  Natural killer cell mediated cytotoxicity
aml04662  B cell receptor signaling pathway
aml04666  Fc gamma R-mediated phagocytosis
aml04670  Leukocyte transendothelial migration
aml04713  Circadian entrainment
aml04720  Long-term potentiation
aml04723  Retrograde endocannabinoid signaling
aml04724  Glutamatergic synapse
aml04725  Cholinergic synapse
aml04726  Serotonergic synapse
aml04727  GABAergic synapse
aml04728  Dopaminergic synapse
aml04730  Long-term depression
aml04750  Inflammatory mediator regulation of TRP channels
aml04911  Insulin secretion
aml04912  GnRH signaling pathway
aml04916  Melanogenesis
aml04918  Thyroid hormone synthesis
aml04919  Thyroid hormone signaling pathway
aml04921  Oxytocin signaling pathway
aml04925  Aldosterone synthesis and secretion
aml04928  Parathyroid hormone synthesis, secretion and action
aml04929  GnRH secretion
aml04931  Insulin resistance
aml04933  AGE-RAGE signaling pathway in diabetic complications
aml04935  Growth hormone synthesis, secretion and action
aml04960  Aldosterone-regulated sodium reabsorption
aml04961  Endocrine and other factor-regulated calcium reabsorption
aml04970  Salivary secretion
aml04971  Gastric acid secretion
aml04972  Pancreatic secretion
aml04973  Carbohydrate digestion and absorption
aml05017  Spinocerebellar ataxia
aml05022  Pathways of neurodegeneration - multiple diseases
aml05031  Amphetamine addiction
aml05032  Morphine addiction
aml05140  Leishmaniasis
aml05143  African trypanosomiasis
aml05146  Amoebiasis
aml05161  Hepatitis B
aml05163  Human cytomegalovirus infection
aml05164  Influenza A
aml05170  Human immunodeficiency virus 1 infection
aml05171  Coronavirus disease - COVID-19
aml05200  Pathways in cancer
aml05205  Proteoglycans in cancer
aml05206  MicroRNAs in cancer
aml05207  Chemical carcinogenesis - receptor activation
aml05214  Glioma
aml05223  Non-small cell lung cancer
aml05225  Hepatocellular carcinoma
aml05231  Choline metabolism in cancer
aml05415  Diabetic cardiomyopathy
Brite
KEGG Orthology (KO) [BR:aml00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    100478007 (PRKCB)
   04012 ErbB signaling pathway
    100478007 (PRKCB)
   04014 Ras signaling pathway
    100478007 (PRKCB)
   04015 Rap1 signaling pathway
    100478007 (PRKCB)
   04310 Wnt signaling pathway
    100478007 (PRKCB)
   04370 VEGF signaling pathway
    100478007 (PRKCB)
   04064 NF-kappa B signaling pathway
    100478007 (PRKCB)
   04066 HIF-1 signaling pathway
    100478007 (PRKCB)
   04020 Calcium signaling pathway
    100478007 (PRKCB)
   04070 Phosphatidylinositol signaling system
    100478007 (PRKCB)
   04071 Sphingolipid signaling pathway
    100478007 (PRKCB)
   04150 mTOR signaling pathway
    100478007 (PRKCB)
 09140 Cellular Processes
  09144 Cellular community - eukaryotes
   04510 Focal adhesion
    100478007 (PRKCB)
   04540 Gap junction
    100478007 (PRKCB)
 09150 Organismal Systems
  09151 Immune system
   04613 Neutrophil extracellular trap formation
    100478007 (PRKCB)
   04650 Natural killer cell mediated cytotoxicity
    100478007 (PRKCB)
   04662 B cell receptor signaling pathway
    100478007 (PRKCB)
   04666 Fc gamma R-mediated phagocytosis
    100478007 (PRKCB)
   04670 Leukocyte transendothelial migration
    100478007 (PRKCB)
   04062 Chemokine signaling pathway
    100478007 (PRKCB)
  09152 Endocrine system
   04911 Insulin secretion
    100478007 (PRKCB)
   04929 GnRH secretion
    100478007 (PRKCB)
   04912 GnRH signaling pathway
    100478007 (PRKCB)
   04921 Oxytocin signaling pathway
    100478007 (PRKCB)
   04935 Growth hormone synthesis, secretion and action
    100478007 (PRKCB)
   04918 Thyroid hormone synthesis
    100478007 (PRKCB)
   04919 Thyroid hormone signaling pathway
    100478007 (PRKCB)
   04928 Parathyroid hormone synthesis, secretion and action
    100478007 (PRKCB)
   04916 Melanogenesis
    100478007 (PRKCB)
   04925 Aldosterone synthesis and secretion
    100478007 (PRKCB)
  09153 Circulatory system
   04270 Vascular smooth muscle contraction
    100478007 (PRKCB)
  09154 Digestive system
   04970 Salivary secretion
    100478007 (PRKCB)
   04971 Gastric acid secretion
    100478007 (PRKCB)
   04972 Pancreatic secretion
    100478007 (PRKCB)
   04973 Carbohydrate digestion and absorption
    100478007 (PRKCB)
  09155 Excretory system
   04960 Aldosterone-regulated sodium reabsorption
    100478007 (PRKCB)
   04961 Endocrine and other factor-regulated calcium reabsorption
    100478007 (PRKCB)
  09156 Nervous system
   04724 Glutamatergic synapse
    100478007 (PRKCB)
   04727 GABAergic synapse
    100478007 (PRKCB)
   04725 Cholinergic synapse
    100478007 (PRKCB)
   04728 Dopaminergic synapse
    100478007 (PRKCB)
   04726 Serotonergic synapse
    100478007 (PRKCB)
   04720 Long-term potentiation
    100478007 (PRKCB)
   04730 Long-term depression
    100478007 (PRKCB)
   04723 Retrograde endocannabinoid signaling
    100478007 (PRKCB)
  09157 Sensory system
   04750 Inflammatory mediator regulation of TRP channels
    100478007 (PRKCB)
  09159 Environmental adaptation
   04713 Circadian entrainment
    100478007 (PRKCB)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    100478007 (PRKCB)
   05206 MicroRNAs in cancer
    100478007 (PRKCB)
   05205 Proteoglycans in cancer
    100478007 (PRKCB)
   05207 Chemical carcinogenesis - receptor activation
    100478007 (PRKCB)
   05231 Choline metabolism in cancer
    100478007 (PRKCB)
  09162 Cancer: specific types
   05225 Hepatocellular carcinoma
    100478007 (PRKCB)
   05214 Glioma
    100478007 (PRKCB)
   05223 Non-small cell lung cancer
    100478007 (PRKCB)
  09172 Infectious disease: viral
   05170 Human immunodeficiency virus 1 infection
    100478007 (PRKCB)
   05161 Hepatitis B
    100478007 (PRKCB)
   05171 Coronavirus disease - COVID-19
    100478007 (PRKCB)
   05164 Influenza A
    100478007 (PRKCB)
   05163 Human cytomegalovirus infection
    100478007 (PRKCB)
  09174 Infectious disease: parasitic
   05146 Amoebiasis
    100478007 (PRKCB)
   05140 Leishmaniasis
    100478007 (PRKCB)
   05143 African trypanosomiasis
    100478007 (PRKCB)
  09164 Neurodegenerative disease
   05017 Spinocerebellar ataxia
    100478007 (PRKCB)
   05022 Pathways of neurodegeneration - multiple diseases
    100478007 (PRKCB)
  09165 Substance dependence
   05031 Amphetamine addiction
    100478007 (PRKCB)
   05032 Morphine addiction
    100478007 (PRKCB)
  09166 Cardiovascular disease
   05415 Diabetic cardiomyopathy
    100478007 (PRKCB)
  09167 Endocrine and metabolic disease
   04931 Insulin resistance
    100478007 (PRKCB)
   04933 AGE-RAGE signaling pathway in diabetic complications
    100478007 (PRKCB)
  09176 Drug resistance: antineoplastic
   01521 EGFR tyrosine kinase inhibitor resistance
    100478007 (PRKCB)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:aml01001]
    100478007 (PRKCB)
Enzymes [BR:aml01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.11  Protein-serine/threonine kinases
    2.7.11.13  protein kinase C
     100478007 (PRKCB)
Protein kinases [BR:aml01001]
 Serine/threonine kinases: AGC group
  PKC family [OT]
   100478007 (PRKCB)
SSDB
Motif
Pfam: Pkinase PK_Tyr_Ser-Thr C1_1 C2 Pkinase_C Kinase-like ABC1 CEP76-C2
Other DBs
NCBI-GeneID: 100478007
NCBI-ProteinID: XP_011232297
Ensembl: ENSAMEG00000014177
LinkDB
Position
10:complement(20241054..20562044)
AA seq 671 aa
MADPAAGPPPSEGEESTVRFARKGALRQKNVHEVKNHKFTARFFKQPTFCSHCTDFIWGF
GKQGFQCQVCCFVVHKRCHEFVTFSCPGADKGPASDDPRSKHKFKIHTYSSPTFCDHCGS
LLYGLIHQGMKCDTCMMNVHKRCVMNVPSLCGTDHTERRGRIYIQAHIEREVLIVVVRDA
KNLVPMDPNGLSDPYVKLKLIPDPKSESKQKTKTIKCSLNPEWNETFRFQLKESDKDRRL
SVEIWDWDLTSRNDFMGSLSFGISELQKAGVDGWFKLLSQEEGEYFNVPVPPEGSEGNEE
LRQKFERAKISQGTKAPEEKTTNTISKLDNNGNRDRMKLTDFNFLMVLGKGSFGKVMLSE
RKGTDELYAVKILKKDVVIQDDDVECTMVEKRVLALPGKPPFLTQLHSCFQTMDRLYFVM
EYVNGGDLMYHIQQVGRFKEPHAVFYAAEIAIGLFFLQSKGIIYRDLKLDNVMLDSEGHI
KIADFGMCKENIWDGVTTKTFCGTPDYIAPEIIAYQPYGKSVDWWAFGVLLYEMLAGQAP
FEGEDEDELFQSIMEHNVAYPKSMSKEAVAICKGLMTKHPGKRLGCGPEGERDIKEHAFF
RYIDWEKLERKEIQPPYKPKARDKRDTSNFDKEFTRQPVELTPTDKLFIMNLDQNEFAGF
SYTNPEFVINV
NT seq 2016 nt   +upstreamnt  +downstreamnt
atggctgacccggctgcggggccgccgccgagcgagggcgaggagagcaccgtgcgcttc
gcccgcaaaggcgccctccgacagaagaacgtgcacgaggtgaagaaccacaaattcact
gcccgcttcttcaagcagcccacattctgcagccactgcaccgacttcatctggggcttc
ggaaagcaaggattccagtgccaagtctgctgttttgttgtgcacaagcggtgccatgaa
tttgtcaccttctcctgcccaggcgccgacaaaggcccagcctccgatgacccccggagc
aaacacaagtttaagatccacacgtactccagccccacgttttgtgaccactgtgggtca
ctgctgtatggactcatccaccaggggatgaagtgtgacacctgcatgatgaacgtgcac
aagcgctgcgtgatgaacgtccccagcctgtgcggcacagaccacacggagcgccgcggc
cgcatctacatccaggcccacatcgagagggaagtcctcattgtagtcgtaagagatgct
aaaaaccttgtacctatggaccccaatggcttgtcagacccttacgtgaaactaaaactg
attcctgaccccaagagcgagagcaagcagaagaccaaaaccatcaagtgctccctcaac
cctgagtggaatgagacattcagattccaactgaaagaatcggacaaagacagaagactg
tctgtagagatttgggattgggatctgaccagcaggaatgacttcatgggatctttgtcg
tttgggatttccgaactgcagaaagctggtgttgatggctggtttaagctgctgagccag
gaggaaggcgaatacttcaatgtgcctgtgccgccggaaggaagcgaaggcaatgaagag
ctgcggcagaaattcgagagggccaagatcagtcaggggaccaaggctccagaagaaaag
acgaccaacaccatatccaaacttgacaacaacgggaacagagaccgaatgaaactgacc
gattttaacttcctgatggtgctcgggaaaggaagctttggaaaggtcatgctctctgag
cgaaaaggcacggacgagctctatgccgtgaagatcctgaagaaggacgtcgtgatccag
gatgacgatgtggagtgcacgatggtggagaagcgggtgctggccctgcctgggaagccg
ccattcctgacccaactgcattcctgcttccagaccatggaccgcctgtactttgtgatg
gagtatgtgaacgggggcgacctcatgtaccacatccaacaagtcggccggtttaaggag
cctcatgctgtattttacgctgcagaaattgccatcggtctgttcttcttacagagcaag
ggcatcatttaccgtgacctcaaacttgacaatgtgatgctggattcagagggccacatc
aagattgctgattttggcatgtgcaaagaaaacatctgggatggggtgaccaccaagaca
ttctgtggcactccagactacatcgcccctgagatcattgcctaccagccctatgggaag
tctgtggattggtgggccttcggagtcctgctgtacgaaatgttggctgggcaggcaccc
tttgaaggggaggatgaggatgagctcttccagtccatcatggaacacaatgtggcttac
cccaagtccatgtccaaggaagctgtggccatctgcaaagggctgatgaccaaacacccg
ggcaaacgtctgggttgcggacccgaaggtgaacgtgacatcaaggagcatgcgtttttc
cggtatattgattgggagaaacttgaacgcaaagagattcagcccccgtataagccaaaa
gccagagacaagcgagacacctccaacttcgacaaagagttcaccagacagcctgtggaa
ctcacgcctaccgataaactcttcatcatgaacttggaccaaaatgaatttgctggcttc
tcctatactaacccagagtttgtcattaatgtgtag

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