KEGG   Ailuropoda melanoleuca (giant panda): 100483319Help
Entry
100483319         CDS       T01329                                 

Gene name
HK1
Definition
(RefSeq) hexokinase 1
  KO
K00844  
hexokinase [EC:2.7.1.1]
Organism
aml  Ailuropoda melanoleuca (giant panda)
Pathway
Glycolysis / Gluconeogenesis
Fructose and mannose metabolism
Galactose metabolism
Starch and sucrose metabolism
Amino sugar and nucleotide sugar metabolism
Neomycin, kanamycin and gentamicin biosynthesis
Metabolic pathways
Carbon metabolism
HIF-1 signaling pathway
Insulin signaling pathway
Type II diabetes mellitus
Carbohydrate digestion and absorption
Central carbon metabolism in cancer
Module
Glycolysis (Embden-Meyerhof pathway), glucose => pyruvate
Nucleotide sugar biosynthesis, glucose => UDP-glucose
Brite
KEGG Orthology (KO) [BR:aml00001]
 Metabolism
  Carbohydrate metabolism
   00010 Glycolysis / Gluconeogenesis
    100483319 (HK1)
   00051 Fructose and mannose metabolism
    100483319 (HK1)
   00052 Galactose metabolism
    100483319 (HK1)
   00500 Starch and sucrose metabolism
    100483319 (HK1)
   00520 Amino sugar and nucleotide sugar metabolism
    100483319 (HK1)
  Biosynthesis of other secondary metabolites
   00524 Neomycin, kanamycin and gentamicin biosynthesis
    100483319 (HK1)
 Environmental Information Processing
  Signal transduction
   04066 HIF-1 signaling pathway
    100483319 (HK1)
 Organismal Systems
  Endocrine system
   04910 Insulin signaling pathway
    100483319 (HK1)
  Digestive system
   04973 Carbohydrate digestion and absorption
    100483319 (HK1)
 Human Diseases
  Cancers
   05230 Central carbon metabolism in cancer
    100483319 (HK1)
  Endocrine and metabolic diseases
   04930 Type II diabetes mellitus
    100483319 (HK1)
Enzymes [BR:aml01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.1  Phosphotransferases with an alcohol group as acceptor
    2.7.1.1  hexokinase
     100483319 (HK1)
Membrane trafficking [BR:aml04131]
 Autophagy
  Mitophagy
   Other mitophagy associated  proteins
    100483319 (HK1)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif Motif
Other DBs
NCBI-GeneID: 
NCBI-ProteinID: 
Ensembl: 
LinkDB All DBs
Position
Un
AA seq 922 aa AA seqDB search
MIAAQLLAYYFTELKDDQVKKIDKYLYAMRLSDETLIDIMTRFKKEMKNGLSRDFNPTAT
VKMLPTFVRSIPDGSEKGDFIALDLGGSSFRILRVQVNHEQNQNVHMESEIYDTPENIVH
GSGSQLFDHVAECLGDFMEKKKIKDKKLPVGFTFSFPCRQSKIDEGILITWTKKFKASGV
EGMDVVKLLNKAIKKRGDYDANIVAVVNDTVGTMMTCGYDDQQCEVGLIIGTGTNACYME
ELRHIDLVEGDEGRMCINTEWGAFGDDGSLEDIRTEFDREIDRGSLNPGKQLFEKMVSGM
YLGELVRLILVKMAKESLLFEGRITPELLTRGKFKTSDVSAIEKNKEGLHNAKEILTRLG
VEPSDDDCISVQHVCTIVSFRSANLVAATLGAILNRLRDNKGTPRLRTTVGVDGSLYKTH
PQYSRRFHKTLRRLVPDSDVRFLLSESGSGKGAAMVTAVXXXAVAYRLAEQHRQIEETLA
HFRLTKDMLLEVKKRMRAEMDMGLRKQTHEKAVVKMLPSFVRSTPDGTEHGDFLALDLGG
TNFRVLLVKIRSGKKRTVEMHNKIYAIPIEIMQGTGEELFDHIVSCISDFLDYMGIKGPK
MPLGFTFSFPCKQTSLDAGILITWTKGFKATDCVGHDVATLLREAIKRREEFDLDVVAVV
NDTVGTMMTCAYEEPTCEVGLIVGTGSNACYMEEMKNVEMLEGNDGRMCINMEWGAFGDN
GCLDDIRTLYDRLVDEYSLNAGKQRYEKMISGMYLGEIVRNILIDFTKKGFLFRGQISET
LKTRGIFQTKYLSQIESDRLALLQVRAILQQLGLNSTCDDSILVKTVCGVVSKRAAQLCG
AGMAAVVDKIRENRGLDHLNVTVGVDGTLYKLHPHFSRIMYQTVKELSPKCNVSFLLSED
GSGKGAALITAVGVRLREETSS
NT seq 2769 nt NT seq  +upstreamnt  +downstreamnt
atgatcgccgcgcagctcctggcctattacttcaccgagctgaaggatgaccaagtcaaa
aagattgacaagtatctctatgccatgcggctctccgatgaaaccctgatagatatcatg
actcgtttcaagaaggagatgaagaatggcctctcccgggattttaatccaacagccaca
gtcaagatgttgccaacgtttgtaaggtccattcctgatggttcagaaaagggagatttc
attgccctggatcttggcgggtcttcctttcgaattctgagggtacaagtgaatcacgag
caaaaccagaatgttcacatggagtccgagatttatgacaccccggagaacatcgtgcat
ggcagtggaagccagctttttgatcacgtggctgagtgcctgggagacttcatggagaaa
aaaaaaatcaaggacaagaaattacctgtgggattcacgttttctttcccctgtcgacag
tccaaaatagacgagggcatcctgataacctggacaaagaaatttaaagcgagcggagtg
gagggaatggatgtggtgaagctgcttaacaaagccatcaagaagcgcggggactacgat
gccaacattgtggccgtggtaaacgacacggtggggaccatgatgacttgtggctacgat
gaccagcagtgtgaagtcggcctcatcatcggcactggcaccaatgcctgctacatggag
gaactgaggcacattgacctggtggaaggcgatgaggggaggatgtgcatcaacacggag
tggggggccttcggcgacgacgggtccctggaagacatccgcaccgagttcgaccgggag
atagaccgtggctctctcaaccctgggaagcagctgtttgagaagatggtcagtggcatg
tacttgggggagctggtgcgactgatcctggtcaagatggccaaggagagcctcttgttt
gaagggcggatcaccccggagctgctcaccagggggaagttcaagaccagcgacgtgtca
gccattgagaagaataaggaaggcctccacaatgccaaagaaatcctgacccgcctggga
gtggagccatccgatgacgactgtatttcagtccagcacgtgtgtaccattgtctcattt
cgctctgccaacctggtggctgcaacgctgggcgccatcttgaaccgccttcgagataac
aagggcacacccaggctgcggaccacggttggtgtcgacgggtctctttacaagacgcac
ccacagtattcccggcgtttccacaagactctgaggcgcttggtgcccgactccgatgtg
cgcttcctcctctcggagagcggcagtggcaagggggcggccatggtcacggcggtgnnn
nnnnnngcggtggcctaccgcctggcggagcagcaccggcagatagaggagaccctggcc
cacttccgcctcaccaaggacatgctgctggaggtgaagaagaggatgcgggccgagatg
gatatgggcctgaggaagcagacgcacgagaaggccgtggtcaagatgctaccctccttt
gtccggagcacgccagacgggactgagcatggtgacttcttggcccttgatcttggagga
acaaatttccgtgtcctgctggtgaaaatccgcagtgggaaaaagagaacagtggaaatg
cacaacaagatctatgccattcccattgaaatcatgcagggcactggggaagagctgttt
gaccacatcgtctcctgcatttctgacttcctggactacatggggatcaaaggccccaaa
atgcctctgggcttcacgttctccttcccctgcaagcagacgagcctggatgcgggaatc
ttgatcacctggaccaagggttttaaggcaaccgactgcgtggggcacgatgtagcaaca
ttactaagggaagcgataaaaaggagagaggaatttgacctggacgtggtggctgtggtc
aatgacactgtgggcaccatgatgacctgtgcttacgaggagcctacctgcgaggttgga
ctcatcgtagggaccggcagcaatgcctgctacatggaagaaatgaagaatgtcgagatg
ctggaggggaatgacgggcgcatgtgtatcaacatggagtggggtgcctttggggacaat
gggtgtctagatgatatcagaacactctatgacagactggtggatgaatattctctaaac
gctgggaaacaaaggtacgagaaaatgattagcggtatgtacctgggtgagatcgtccgc
aacatcttgatcgacttcaccaagaagggcttcctcttccgagggcagatctccgagacg
ctgaagacccggggcatctttcagaccaaatacctttcccagattgagagtgaccgatta
gcgctgctccaggtccgggccatcctccagcagctgggcctgaacagcacctgtgacgac
agtatcctggtcaagactgtgtgcggggtggtgtccaagagggccgcgcagctgtgtggt
gcgggcatggctgccgtggtggataagatccgagagaacagagggctggaccacctcaac
gtgactgtgggggtggatggaacactctacaagcttcatccgcacttctccagaatcatg
taccaaaccgtgaaggaactgtcaccaaaatgtaacgtgtccttcctcctgtccgaagac
ggtagcggcaagggggccgccctcatcacggcggtgggcgtccggctccgggaagagacg
agcagctaa

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