Amycolatopsis keratiniphila: AORI_5800
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Entry
AORI_5800 CDS
T02678
Symbol
aceE
Name
(GenBank) pyruvate dehydrogenase E1 component
KO
K00163
pyruvate dehydrogenase E1 component [EC:
1.2.4.1
]
Organism
aoi
Amycolatopsis keratiniphila
Pathway
aoi00010
Glycolysis / Gluconeogenesis
aoi00020
Citrate cycle (TCA cycle)
aoi00620
Pyruvate metabolism
aoi00785
Lipoic acid metabolism
aoi01100
Metabolic pathways
aoi01110
Biosynthesis of secondary metabolites
aoi01120
Microbial metabolism in diverse environments
aoi01200
Carbon metabolism
aoi01210
2-Oxocarboxylic acid metabolism
Module
aoi_M00307
Pyruvate oxidation, pyruvate => acetyl-CoA
Brite
KEGG Orthology (KO) [BR:
aoi00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00010 Glycolysis / Gluconeogenesis
AORI_5800 (aceE)
00020 Citrate cycle (TCA cycle)
AORI_5800 (aceE)
00620 Pyruvate metabolism
AORI_5800 (aceE)
09108 Metabolism of cofactors and vitamins
00785 Lipoic acid metabolism
AORI_5800 (aceE)
Enzymes [BR:
aoi01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.4 With a disulfide as acceptor
1.2.4.1 pyruvate dehydrogenase (acetyl-transferring)
AORI_5800 (aceE)
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Gene cluster
GFIT
Motif
Pfam:
PDH_E1_M
Transketolase_N
Transketolase_C
Motif
Other DBs
NCBI-ProteinID:
AGM08383
UniProt:
R4TDC5
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Position
6556546..6559341
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AA seq
931 aa
AA seq
DB search
MAPQNDGASGKETPARVRVIRDGLAAHLPDIDPEETAEWLDSFDEALARGGQQRARYLML
RILERARERHVGVPALTSTDYVNTIPTENEPWFPGDEEIERRYRAYIRWNAAIMVHRAQR
PGVGVGGHISTYGSSAALYEVGFNHFFRGKDHSGGGDQIFIQGHASPGIYARAFLEGRLT
ESQLDGFRQEFSHAGEGGGLPSYPHPRLMPEFWENPTVSMGLGPMNAIYQARFNRYLRDR
GIKDTSDQHVWAFLGDGEMDEPESRGLIHVAASEGLDNLTFVINCNLQRLDGPVRGNGKI
IQELESYFRGAGWNVIKVIWGREWDSLLHADRDGALVNLMNTTPDGDFQTYKANDGAFVR
EHFFGRDPRTKELVKDLTDADVWNLKRGGHDYRKVYAAYKSSLEHHGQPTVILAHTIKGY
GLGPSFEGRNATHQMKKLTLDDLKLFRDAQRIPISDEELERDPKLPPYYHPGKESPEIEY
MIGRRRALGGFLPERRPKASKALVLPGDKVYEGIRKGSGKQEVATTMAFVRLVRELAKDS
EIGKRIVPIIPDEARTFGLDSMFPTAKIYNPHGQTYTSVDASLMLAYKESEKGVILHEGI
NEAGSTASFTAVGTSYATHGEPMIPIYIFYSMFGFQRTGDGLYAAADQMARGFVLGATAG
RTTLTGEGLQHADGHSLLLAATNPAVVAYDAAWSFEIAHIVRDGLRRMYGETGPDGNGEN
IFYYMTIYNEPYQQPAEPENLDVDGLLKGLYKYADAPSGDGPEAQILVSGVTMPDALRAQ
QMLAEEWGVRAAVWSATSWTELRREAVEVDHDNLLHPGDSPRVPYITQKLSGVNGPVVAV
SDWMRAVPDLIRPWVPTDMLTLGTDGFGFSDTRPAARRKFLVDAQSIVVGTLSALAKRGE
IDQSKAAEAARKYRLDDVAAAGPQLSDSGSA
NT seq
2796 nt
NT seq
+upstream
nt +downstream
nt
ttggccccgcagaacgacggcgcctccggcaaggagaccccggcacgcgtccgcgtcatc
cgtgacggattggcggcgcacctgcccgacatcgacccggaggagaccgccgaatggctg
gactccttcgacgaggcgctggccaggggtggtcagcagcgcgcccggtacctgatgctg
cgcatcctcgagcgggccagggaacgccacgtcggcgtcccggcgctgacgtcgacggac
tacgtcaacaccatccccaccgagaacgaaccctggttccccggtgacgaggagatcgaa
cgccggtaccgcgcctacatccggtggaacgccgcgatcatggtgcaccgcgcgcagcgt
cccggcgtcggcgtcggcgggcacatctcgacctacggctcgtccgcggcgctgtacgaa
gtgggcttcaaccacttcttccgcggcaaggaccactcgggcggcggcgaccagatcttc
atccagggccacgcctcccccggcatctacgcccgcgcgttcctcgagggcaggctgacc
gagagccagctggacggcttccgccaggagttctcgcacgccggcgagggcggcggcctg
ccgtcgtacccgcacccccggctgatgccggagttctgggagaacccgaccgtgtccatg
ggcctcggcccgatgaacgcgatctaccaggcgcgattcaaccgctacctgcgcgaccgc
ggcatcaaggacaccagcgaccagcacgtctgggcgttcctcggcgacggcgagatggac
gagccggaatcgcgcggcctcatccacgtggccgcgagcgagggcctcgacaacctgacc
ttcgtgatcaactgcaacctgcagcggctcgacggcccggtgcgcggcaacggcaagatc
atccaggagctggagtcgtacttccgcggcgccggctggaacgtcatcaaggtcatctgg
ggccgcgagtgggactcgctgctgcacgcggaccgtgacggcgcgctggtcaacctgatg
aacaccacgccggacggcgatttccagacctacaaggccaacgacggcgcgttcgtccgc
gagcacttcttcggccgcgacccgcggaccaaggaactcgtcaaggacctcaccgacgcc
gacgtctggaacctcaagcgcggcgggcacgactaccgcaaggtctacgcggcctacaag
tcgtcgctggagcaccacggccagccgacggtgatcctggcccacaccatcaagggttac
ggcctcggaccgtccttcgagggccgcaacgccacgcaccagatgaagaagctcaccctc
gacgacctcaagctgttccgggacgcccagcgcatcccgatcagcgacgaggagctcgag
cgcgacccgaagctgccgccgtactaccacccgggcaaggaatcgccggagatcgagtac
atgatcggccgccgccgcgcgctcggcgggttcctgccggagcgccgcccgaaggcctcg
aaggccctcgtgctgcccggcgacaaggtctacgaaggcatccggaagggctcgggcaag
caggaggtcgccaccacgatggcgttcgtccggctcgtccgcgagctggcgaaggactcc
gagatcggcaagcggatcgtcccgatcatcccggacgaggcgcgcaccttcggcctcgac
tcgatgttcccgacggccaagatctacaacccgcacggccagacgtacacgtcggtcgac
gcgagcctgatgctggcctacaaggagtccgaaaagggcgtcatcctgcacgagggcatc
aacgaggcgggctcgaccgcgtcgttcaccgccgtcggcacctcgtacgccacgcacggc
gagccgatgatcccgatctacatcttctactcgatgttcgggttccagcggaccggtgac
ggcctctacgcggcggcggaccagatggcccgcgggttcgtgctcggcgccaccgccggc
cgcaccacgctgaccggcgagggcctccagcacgccgacgggcactcgctgctgctggcg
gcgaccaacccggccgtcgtggcctacgacgcggcgtggtcgttcgagatcgcccacatc
gtgcgggacggtcttcgccggatgtacggcgagaccgggccggacggcaacggcgagaac
atcttctactacatgacgatctacaacgagccctaccagcagcccgccgagcccgagaac
ctcgacgtcgacggcctgctcaagggtctctacaagtacgcggacgccccgtcgggcgac
ggcccggaggcgcagatcctggtctccggcgtcaccatgcccgacgcgctgcgggcgcag
cagatgctggccgaggagtggggcgtgcgcgcggccgtgtggtcggcgacgtcgtggacc
gagctgcgccgcgaggccgtcgaggtcgaccacgacaacctgctccacccgggcgactcc
ccgcgtgtgccgtacatcacgcagaagctgtccggcgtgaacgggccggtcgtcgcggtc
tcggactggatgcgggccgtgccggacctcatccgcccctgggtgccgaccgacatgctg
acgctgggcaccgacgggttcggcttctccgacacccgccccgccgcccggcggaagttc
ctggtcgacgcccagtcgatcgtggtcggcacgctgagcgcgctggccaagcgcggcgag
atcgaccagtcgaaggcggcggaggcggcgcgcaagtaccgcctcgacgacgtcgcggcc
gcgggtccgcagttgtcggactccggtagcgcctga
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