Amycolatopsis orientalis: SD37_33730
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Entry
SD37_33730 CDS
T06703
Name
(GenBank) non-ribosomal peptide synthetase
KO
K16428
nonribosomal peptide synthetase CepA
Organism
aori
Amycolatopsis orientalis
Pathway
aori01055
Biosynthesis of vancomycin group antibiotics
Brite
KEGG Orthology (KO) [BR:
aori00001
]
09100 Metabolism
09109 Metabolism of terpenoids and polyketides
01055 Biosynthesis of vancomycin group antibiotics
SD37_33730
09180 Brite Hierarchies
09181 Protein families: metabolism
01008 Polyketide biosynthesis proteins [BR:
aori01008
]
SD37_33730
Polyketide biosynthesis proteins [BR:
aori01008
]
Nonribosomal peptide synthetase (NRPS)
Linear NRPS
Vancomycin synthetase
SD37_33730
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
AMP-binding
Condensation
PP-binding
AMP-binding_C
Reovirus_L2_8th
Motif
Other DBs
NCBI-ProteinID:
ANN20078
UniProt:
A0A193C6U2
LinkDB
All DBs
Position
complement(7774874..7784305)
Genome browser
AA seq
3143 aa
AA seq
DB search
MNSAARTAVTVLELFASQVERMPGAVAVVDGDRVLTYRELDEAAGLLAGRLAARGIRHGD
RVAVMMGRSADLLVALLAVWKAGATYVPVDAAYPAPRVEFMVRDSAAALMVCSVASRDAV
PEGIDSLVVDAATDEDGRAATATVRPEDLAFVMYTSGSTGRPKGVAITQGSVADLVRDPG
WAMGPDDAVLMHSPHAFDASLFEVWTPLASGARVVIAEPGSVDVRRLRAAAAAGVTRVYL
TAGSFRAVAEEAPESFAAFREVLTGGDVVPAHAVQRVRQACPEARFRNMYGPTEATMCAT
WYPLEPGEVLGSVVPIGRPLVGRRVQVLDESLRPVGPGVVGDLYLSGCLAEGYFNRPGLT
AERFVADPSAPGQRMYWTGDLAQWTADGVLLFAGRADDQVKVRGFRIEPGEIEAALIAQP
EVHDAVVAAIEGRLIGYVVAEEGVDPVLVRERLRAELPEYLVPAVVLTLDALPLTRNGKV
DRAALPAPEFATGAAGREPATEEERVLCGLFADVLRLDRAGVDDGFFDLGGDSIFAMRLA
ARAAKAGLLVTPVQIFEEKTPARLAAVARPVPADEPLDGPLLSLTEAEEAELAIAAPGAE
EIWPLAPLQEGLLFESILDDQGSDIYQVQVILELNGPLDEARLRAAWDTVVHRHPELRLT
FHRLESGKTVQAVHGDVAVPWRAVDLAGADDVDAAVEALAGQEQGKRFDLAKAPLVRLVL
IRTGEDRHRLLFVIHHILVDGWSVAVILNEVADAYTAGGRLPAQRGGASFKDYLAWLDRQ
DKDAARAAWRDELAGLDEPALIATTSVETDYDYRATHLTSALHTRLLEFAREHGLTPSTV
VHAAWALVLARLTRRTDVVFGTMVATRPAELEGIESMPGLLMSAVPVRVPLDGGQPVVDL
LTDLHTRQTALKPHQHLGLPEIQKAAGPGAGFDTLLVIENYPREYAAQFTHLRTIEGTHY
PLTLGITPGERFKIQLGYWQGQVPDAVAESLLEWFVGAIGALVADPARPVGRIGVGTAET
REWAAPLVAGEPLPTLVGRIAARLPDNVALVDSAGELSYAELWERSLKLAAVLRDNGVGS
ESRVGLVVGRSSWWTVGMLGVLLAGGTFVPVDPAYPDERKEWIFRSADPMLVVCEGTTRR
AVPVEFADRLLVVDDVDLSARPEAELPRVDPRSAAYVIYTSGSTGTPKGVVVTHTGLGNL
ALAHIDRFRVTPSSRVLQFAALGFDTIVSEVMMALLSGATLVVPPEQELPPRMAFSETLE
RWGITQVKAPPSVLGTVDALPPTVETVVAAGELCPPGLVDRLSADRRMINAYGPTETTIC
ATMSLPLTPRQHPIPFGGPVPGVRGYLLDSFLRPLPPGVTGELYLSGIGVARGYLGRPGL
TAERFVADPFAPGERMYRTGDLAYWTDQGELVSAGRADDQVKIRGFRVEPREIEFALSAY
PRITQATVTVREDRLLAYVTPGDIDTQAVRKHLASRMPQYMVPAAVVALDTLPLTAHGKI
DRRALPDPEFTTGAPAREPATETERVLCELFAGVLGLEQVGVDDSFFDLGGDSILSMQLA
ARARRSGLTFSAADVFDGKTPERIARLAEESAPPEPGRPAKSDGVGEVPWTPVTRLLGEG
VTGSAFAQWMVVGAPADLTEETVAAGFAAVVDAHDMLRARVVDEEGGRRLLVGERGSVTG
SVTRVGLDGRPVDEVVEEAARDAVSRLDPSAGVLARAVWVDAGPDRIGRLVVVVHHLSVD
GVSWRVLLSDLQAACEAVAAGREPVLEPVGVSFKRWAGLLGEWAVSAERVGELAAWQAIL
GQEQPVATRELTTSQAAKGAVRSRSWVVPKAETSALTGRAPVVFHCGVHEILLAGLAGAV
TRWRGGDTVLVDVESHGRHPADGMDLSRTVGWFTSAHPVRLEVAGTELADVLAGGPAAGR
LLKTVKEQSRAVPGDGLGYGLLRYLNDTTAPVLAELPSARIGFNYMGRFATGEDSGVRAW
QPVGDIGSSLEPGMGLPHAIEVNAIVQDLPDGPELTLMLEWQEDLLGEAEIDQLGQGILA
VLAGLARQAEDPAAGGHTASDFDLVALGQDEIEALEAEFADAGGVADLLPLSPLQHGLAF
HAGFSGDGVDVYTAQAVLELTGPLDMPLLRKSVRALLDRHANLRAGFRHAADGSAYQVIP
GALAVPVTLVDVTGSADPEAEAAAVAAADRAQPFDLAKPPLLRLTVVALGENGHRLVLTN
HHILLDGWSTPLLLDELLTLYRDGAVPSALAPVNPYREYLAWVRETDRDAAITAWRDALA
GLPEPTLVAADRTVPVQVPGQMWAELGEAFAGALAARARECGVTVSTVLQAVWGMVLAAI
TGRDDVVFGAVVSGRPAELPGIETMVGLFINTVPVRVRMDPRHTFAELVKEVQDEQIALL
AHHHVGLTDIQQAAGLGRLFDTLVVYENYPRPAEAADAEPDRLRVLGMTAADATHYPLAL
AVVPGESLRLRLEHQPALFTTEQAAAVLERFTRVLEAVVAAPGTPLAAVPILSESEQREL
RARNDTAVPVPDRTLPELFAAQVAATPEATAVTFEDRSLSYAELDARADRLARRLIERGV
GPEGLVAVMLPRSLDLVVTVLAITKTGGAWLPIDPVYPADRVTYILDDAEPALVITSAAL
AASPAGEVLAARPSTVVLDDLAIAGGEHVPVADADRVRPLDPRHPAYLIYTSGSTGRPKA
VVVTHRNLANYLFHCGTKYPGLRGRSLLHSSIAFDLTVTAMLTPLTVGGTVQVGALEDLI
GTVGSAPALFLKATPSHLKTLETGSREIAVPGDLLLGGEQLSVETVADWRRTYPNTVVVN
EYGPTEATVGCVEYRLEPGQAAPSGDVVPIGTPMTNMRAFVLDSWLRPVPPGAVGELYVS
GAGVARGYLGRAGLTATRFVADPFGAGGLMYRTGDLVRWNTDGELVFAGRVDDQVKVRGY
RIEPGEIEAALEAHESVGQAVVLARDSASGKRLIGYVTPAGVDGAAVRAAVAARLPEYMV
PAAVVALDALPLTANGKVDRDALPDPDFNERVSGREPVTEAERLLCALFAEVLGLERAGA
DDSFFELGGDSILSMRLAARAHREGMAFGAREVFELRTPAGIAAIVERAPAVPAAADYAA
SDVALLELNQDEIDEFEAEFDAS
NT seq
9432 nt
NT seq
+upstream
nt +downstream
nt
atgaattccgcagcgcggaccgccgtgacggtgctggagctgttcgcctcgcaggtggag
cggatgcccggcgcggtggccgtggtcgacggcgaccgggtgctgacctaccgggaactc
gacgaggccgcgggcctgctggccggacggctggcggcccggggcatccgccacggcgac
cgggtcgcggtgatgatgggccgctcggcggatctgctggtggcgttgctcgccgtgtgg
aaggcgggcgcgacgtacgtaccggtggacgccgcctatccggcgccgcgtgtggaattc
atggtgcgcgattcggcggccgcgctgatggtgtgctcggtcgcgtcgcgtgacgccgtg
ccggagggcatcgattcgctcgtggtggacgccgccacggacgaggacgggcgtgcggcg
acggccacggtgcgcccggaggacctggcgttcgtgatgtacacctccggctcgacgggc
aggcccaagggggtggcgatcacccagggcagtgtcgcggacctggtgcgggatcccggt
tgggcgatggggccggacgacgccgtgctgatgcattcgccgcacgccttcgacgcgtcc
ttgttcgaggtctggacgccgctggcctcgggtgcgcgggtggtgatcgccgaaccgggt
tcggtggacgtccggcgcctgcgcgccgcggccgcggccggggtgacgagggtgtacctg
accgcggggagtttccgcgcggtggcggaggaggcgccggagtcgttcgcggccttccgt
gaggtgctgaccggcggtgacgtggtgcccgcgcacgccgtgcagcgggtgcggcaggcc
tgtcccgaggcgcggttccggaacatgtacgggccgacggaagcgacgatgtgcgcgacg
tggtacccgctggaaccgggtgaggtactgggttcggtggtgccgatcgggcgtccgctg
gtcggccgccgggtccaggtgctcgacgaatcgctgcgcccggtggggccgggtgtggtc
ggcgacctgtacctctccggatgtctggcggagggctacttcaaccggccggggctgacg
gcggagcggttcgtcgcggatccctccgcgccgggacagcggatgtactggacgggtgac
ctcgcccagtggacggcggacggtgtgctgctgttcgcgggccgcgccgacgaccaggtg
aaggtccgcgggttccggatcgagcccggcgagatcgaggccgcgctgatcgcccagccg
gaggtccacgacgccgtggtcgcggcgatcgagggacggctgatcggctacgtggtggcc
gaggagggcgtggatcccgttctcgtccgcgagcgcctacgcgcggaattgccggaatac
ctggtgcccgcggtcgtcctcacgctggacgcgttgccgttgacccgtaacggaaaggtg
gacagggcggcgctgcccgcgcccgagttcgcgacgggcgccgcgggccgtgaacccgcc
accgaggaggaacgcgtcctttgtggactgttcgccgacgtgctacggctcgaccgggcc
ggggtcgacgacggcttcttcgatctgggcggggattccatcttcgcgatgcgcctggcg
gcacgggcggccaaggcgggcctgctggtgacacccgtccagatcttcgaggagaagacg
cccgcgcggctggcggcggtggcgcgtccggtaccggccgacgagccgctcgacggcccc
ctgctcagtttgaccgaggccgaagaggcggagctggcgatcgccgctccgggtgccgag
gagatctggccgctggcgccgttgcaggaggggttgctcttcgagtcgatcctggacgac
cagggctccgacatctaccaggtgcaggtgatcctggagctgaacggaccgctggacgag
gcccggctgcgggccgcgtgggacacggtcgtccaccggcaccccgagcttcggctcacc
ttccaccggctcgagtcgggaaagacggtgcaggccgtccacggcgacgtcgccgtgccg
tggcgggcggtggatctggcgggcgccgacgacgtcgacgcggccgtcgaggccttggcc
ggacaggaacaggggaagcggttcgatctcgccaaggcaccgctggtccggctggtgctg
atccgcaccggcgaggaccggcaccggctgctgttcgtcatccaccacatcctggtcgac
ggctggtcggtggcggtgatcctcaacgaggtcgccgacgcgtacacggcgggcggacgg
ctgccggcacagcgcggcggcgcctccttcaaggactacctggcgtggctggaccggcag
gacaaggacgcggcgcgggcggcctggcgcgacgagctggccggtctcgacgagcccgcg
ctgatcgcgacgacgtccgtcgagacggactacgactaccgcgccacccacctcacctcg
gcgctgcacaccaggttgctggagttcgcccgtgagcacgggctgacgccgagcacggtg
gtgcacgccgcctgggcgctggtgctggcgcgtctcacgcggcggaccgacgtggtgttc
ggcaccatggtcgcgacccgccccgcggaactcgagggtatcgagtcgatgccgggcctg
ctgatgagcgcggtaccggtgcgggtgcccctcgacggcggccaaccggtcgtggacctg
ctgaccgacctgcacaccaggcagacggccctcaaaccgcatcagcatctgggcctgccg
gagatccagaaggcggccggacccggcgcgggcttcgacacgctgctggtgatcgagaac
tacccgcgggagtacgccgctcagttcacgcatctgcgcaccatcgaaggcacgcactat
ccgctgaccctcggcatcacgccgggggagcggttcaagatccagctcggctactggcag
ggacaggttcccgacgccgtcgccgaatcgctgctggagtggttcgtcggcgcgatcggc
gcgctggtcgccgatccggcccgcccggtggggcggatcggggtgggcaccgccgagacg
cgcgagtgggccgcgccgttggtggcgggagagccgctgccgacgctggtcgggcggatc
gcggcgcggctgccggacaacgtggcgctggtggacagcgcgggtgagctgtcctacgcg
gagttgtgggagcggtcgctgaagctcgcggccgtgttgcgggacaacggtgtcgggtcc
gagagccgcgtcggcctggtggtggggcgctcgtcctggtggacggtcggcatgctgggc
gtgttgctggccggtggcactttcgtgccggtggacccggcctatccggacgagcgcaag
gaatggatcttccggagtgcggatccgatgctggtggtgtgcgaggggacgacgcggcga
gcggtgccagtcgagttcgcggaccggctgctggtggtcgacgacgtcgacctgtcggcg
aggccggaagcggagctgccgcgagtggatccgcgcagcgccgcgtacgtgatttacacg
tcggggtcgacgggaactccgaagggggtcgtcgtcacccataccggactgggaaacctg
gcgctggcgcatatcgaccggttccgggtgacgccgtcgtcgcgggtcctgcagttcgcc
gcgctcggcttcgacaccatcgtgtccgaggtgatgatggcgctgctgtcgggcgcgacg
ctggtcgtgccgccggagcaggaactgccgccccggatggcgttctccgaaacgctggaa
cggtggggcatcacgcaggtgaaggcgccgccgtcggtgctgggcacggtcgacgcgctg
ccgccgaccgtggagacggtggtggcggcgggcgaactctgcccgccgggtctggtggac
cggctgtccgcggaccggcggatgatcaacgcctacgggccgaccgagaccacgatctgc
gcgacgatgagcctgccgctgacgccgcgccagcatccgatcccgttcggtggcccggtt
ccgggggtgcgcggatacctgctggactcgttcctgcgtccgctgccgcccggggtgacc
ggtgagctgtacctgtccgggatcggggtggcccgcggctatctgggccgtccggggctg
acggccgagcggttcgtggccgatccgttcgcccccggcgagcggatgtaccggaccggg
gacctggcctactggaccgaccagggtgagctggtgtccgccgggcgcgccgacgaccag
gtcaagatccgcgggttccgggtcgaaccgcgcgagatcgagttcgccttgtccgcctat
ccccggatcactcaggccacggtgaccgtccgcgaagaccgcctgctcgcctacgtgaca
ccgggcgacatcgacacgcaggcggtgcggaaacatctcgcgtcccggatgccccagtac
atggtgcccgcggcggtggtggcgctggacaccctgccactgacggcgcacgggaagatc
gaccggcgcgcgctgcccgatcccgaattcaccaccggggcgcccgccagggaaccggcc
accgagaccgagcgggtgctgtgcgagttgttcgccggtgtcctcggtctggagcaggtc
ggggtggacgacagtttcttcgatctgggcggggactccatcctttcgatgcagctggcg
gcgcgggcacggcgttcggggctgacgttctccgcagccgacgtcttcgacgggaagacc
ccggagcggatcgcgcggctggcggaggagtcggcgccgccggagccggggcgtccggcg
aagtccgacggtgtgggcgaagtcccgtggacgccggtgacgcggctgctgggcgaaggc
gtcacgggatcggcgttcgcgcagtggatggtggtgggcgcgcccgcggatctgacggag
gagacggtggcggccgggttcgcggccgtggtggacgcgcacgacatgctgcgggcgcgg
gtcgtcgacgaggagggcggccgtcgcctgctggtcggcgagcgtgggtcggtgaccggg
tcggtcacccgcgtgggactggacggccgtccagtggacgaggtcgtcgaggaggcggcg
cgagacgccgtgagcaggctggatccgtcggcgggcgtgctggcgcgggcggtgtgggtg
gacgccggaccggaccggatcgggcggctcgtggtggtggtgcaccacttgtcggtcgac
ggtgtgtcgtggcgggtgctgctctcggatctgcaagccgcctgcgaggcggtggccgcg
ggccgggagccggtgctggagccggtgggggtgtccttcaagcggtgggcgggcctgctc
ggtgagtgggcggtctccgcggagcgcgtcggcgaattggcggcgtggcaggcgatcctc
ggacaggagcagccggtcgccacccgtgagctgaccacgagtcaggccgcgaagggtgca
gtgcgctcgcggtcgtgggtggtgccgaaggcggagacgtcggcactgaccgggcgggct
cccgtggtgttccactgcggcgtccacgagatcctgctcgccgggctggccggagcggtg
acgcggtggcgtggcggggacacggtcctggtggacgtggaaagccacggccgccatccg
gccgacgggatggatctgtcccggacggtgggctggttcaccagcgcgcatccggtccgg
ctggaagtggcggggaccgagctggccgacgtgctcgccggtggcccggcggccgggcgt
ctgctgaagacggtcaaggagcagtcgcgggccgtgcccggcgacgggctcggctacgga
ctgctgcgctatctcaatgacacgaccgcgccggtactggcggaactgccgtcggcgcgg
atcgggttcaactacatgggcaggttcgccaccggtgaggacagcggggtccgggcgtgg
cagccggtcggggacatcggcagctcgctcgaacccggaatgggcttgccgcacgcgatc
gaggtcaacgcgatcgtccaggacctgccggacggtcccgaactgacgctcatgctggaa
tggcaggaggatctgctcggcgaggccgagatcgaccagctgggccaagggattctggcc
gtgctggccgggcttgcccggcaggcggaggatcccgccgcgggcgggcacaccgcgtcc
gacttcgatctcgtcgccttgggccaggacgagatcgaggccctcgaagccgaattcgcg
gacgccggtggggtggccgacctgctgccgctgtcgccgttgcagcacggtctcgccttc
cacgccggtttctccggtgacggcgtcgatgtctataccgcgcaggcggtcctggagctg
accggaccgctggacatgccattgctgcggaagtccgtccgcgcgctgctggacaggcac
gcgaacctgcgcgccggcttccggcacgccgccgacgggtccgcgtaccaggtgatcccc
ggtgccttggcggtgccggtgaccctggtggacgtgaccgggtcggcggatccggaagcg
gaagcggcggcggtggccgcggcagaccgggcccagccgttcgatctggccaagcccccg
ctgctgcggttgacggtggtggccttgggcgagaacggccaccggctggtgctgaccaac
caccacatcctgctcgacggctggtcgacgccgctgctgctggacgaactgctcacgctg
taccgcgacggggcggttccgtccgcgctggcgccggtcaacccgtaccgggagtacctg
gcctgggtgcgcgaaaccgatcgggacgcggcgatcaccgcctggcgcgacgccttggcg
gggctgccggaaccgacgctggtcgcggccgaccggacggtcccggtccaggtgcccggg
cagatgtgggccgaactgggcgaggcgttcgccggtgcgctggcggcgcgggcccgcgaa
tgcggggtcaccgtcagcacggtgctgcaggcggtgtggggcatggtgctggccgcgatc
accggacgcgacgacgtcgtgttcggggcggtggtgtccggccgcccggcggaactgccc
gggatcgagaccatggtcgggctgttcatcaacaccgtcccggtccgggtccggatggac
ccccggcacaccttcgccgaactggtgaaggaagtgcaggacgagcagatcgccttgctg
gcccatcaccacgtcggcctcaccgacatccagcaggccgccgggctgggcaggttgttc
gacaccctcgtcgtctacgagaactacccgcgacccgccgaggccgccgacgcggaaccg
gatcggttgcgggtgctgggaatgaccgccgccgacgccacgcactatccgctggcgctg
gccgtcgtcccgggcgaaagcctgcggctgcggctggagcaccagcccgcgctgttcacc
accgagcaggcggccgccgtgctggagcggttcacgcgggtgctcgaagccgtggtcgcc
gctccggggacgccgctcgcggcggtgccgatcctgtccgagtccgaacagcgagagctg
cgggcgcgcaacgacaccgcggtgccggtgccggaccggacgctgccggagttgttcgcc
gcgcaggtcgccgccaccccggaggcgaccgcggtgaccttcgaggaccggtcgctgtcc
tacgccgaactcgacgcccgtgccgatcggctggcacgccggctcatcgagcggggtgtc
ggtcccgaaggcctggtcgcggtgatgctgccccggtcgctggacctggtcgtcacggtg
ctggcgatcaccaagaccggcggtgcctggctgccgatcgatccggtctatccggccgat
cgtgtcacctacatcctcgacgacgccgaaccggcattggtgatcacgagcgccgcgctg
gcggcctcgcccgccggtgaggtgctggcggcacggccctcgacggtggtgctcgacgat
ctcgcgatcgcgggcggcgagcacgtgccggtcgccgacgccgatcgggtccggccgctg
gatccgcgtcatccggcctacctcatctacacctcgggctcgaccggccgtcccaaggcc
gtcgtcgtcacccaccggaatctggcgaactatctgttccactgcgggacgaagtacccg
gggctgcggggacggtcgctgctgcattcgtcgatcgccttcgatctgacggtcaccgcg
atgctcaccccgctcaccgtcgggggaacggtccaggtcggtgcgctggaagacctgatc
ggcacggtgggaagcgccccggcgctgttcctcaaggccacgccgagccatctgaagacg
ttggagaccggctcccgggagatcgccgttcccggtgatctcctgctcggcggcgaacag
ttgtccgtcgagacggtcgccgactggcgccggacgtacccgaacaccgtggtggtcaac
gaatacggcccgaccgaggcgacggtcggctgcgtcgaataccggctcgaacccgggcag
gcggcgccgtccggcgacgtggtgccgatcggcaccccgatgacgaacatgcgggcgttc
gtcctggattcgtggctgcggccggtgccgccgggcgcggtgggcgagttgtacgtgtcc
ggcgcgggcgtggcccggggctatctggggcgggcggggctgaccgcgacgcggttcgtg
gccgatccgttcggtgccggtgggctgatgtaccggaccggggacctggtgcggtggaac
acggacggggaactggtcttcgccggccgtgtcgacgaccaggtgaaggtgcggggatac
cgcatcgaacccggtgagatcgaggcggcactggaggcgcacgaatcggtggggcaggca
gttgtcttggcccgcgacagtgcctccggcaaacggctgatcggttatgtgacgcctgcc
ggggtggacggggccgcggtgcgcgcggccgtggcggcccggttgccggagtacatggtg
cccgcggcggtggtggcgctcgacgcgcttccgttgacggcgaacgggaaagtggaccgg
gacgcgctgccggatcccgacttcaacgaacgcgtctccggccgggagccggtcacggag
gccgaacggctgctgtgcgcgcttttcgccgaggtgctcggcctggagcgggcaggcgcg
gacgacagtttcttcgaactgggcggggattcgatcctgtcgatgcgactggcggcgcgg
gcgcaccgcgagggaatggccttcggcgcacgcgaggtgttcgagctgcggacgcccgcc
gggatcgcggcgatcgtcgagcgggcaccggctgttcccgccgcggcggactacgccgct
tccgacgtcgccctgctggaactgaaccaggacgagatcgacgaattcgaggcggagttc
gacgcctcgtga
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integrated database retrieval system
