Actinomyces radicidentis: AXF14_01190
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Entry
AXF14_01190 CDS
T04288
Symbol
kgd
Name
(GenBank) alpha-ketoglutarate decarboxylase
KO
K01616
multifunctional 2-oxoglutarate metabolism enzyme [EC:
2.2.1.5
4.1.1.71
1.2.4.2
2.3.1.61
]
Organism
ard
Actinomyces radicidentis
Pathway
ard00020
Citrate cycle (TCA cycle)
ard00630
Glyoxylate and dicarboxylate metabolism
ard00785
Lipoic acid metabolism
ard01100
Metabolic pathways
ard01110
Biosynthesis of secondary metabolites
ard01120
Microbial metabolism in diverse environments
ard01200
Carbon metabolism
ard01210
2-Oxocarboxylic acid metabolism
Module
ard_M00011
Citrate cycle, second carbon oxidation, 2-oxoglutarate => oxaloacetate
Brite
KEGG Orthology (KO) [BR:
ard00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00020 Citrate cycle (TCA cycle)
AXF14_01190 (kgd)
00630 Glyoxylate and dicarboxylate metabolism
AXF14_01190 (kgd)
09108 Metabolism of cofactors and vitamins
00785 Lipoic acid metabolism
AXF14_01190 (kgd)
Enzymes [BR:
ard01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.4 With a disulfide as acceptor
1.2.4.2 oxoglutarate dehydrogenase (succinyl-transferring)
AXF14_01190 (kgd)
2. Transferases
2.2 Transferring aldehyde or ketonic groups
2.2.1 Transketolases and transaldolases
2.2.1.5 2-hydroxy-3-oxoadipate synthase
AXF14_01190 (kgd)
2.3 Acyltransferases
2.3.1 Transferring groups other than aminoacyl groups
2.3.1.61 dihydrolipoyllysine-residue succinyltransferase
AXF14_01190 (kgd)
4. Lyases
4.1 Carbon-carbon lyases
4.1.1 Carboxy-lyases
4.1.1.71 2-oxoglutarate decarboxylase
AXF14_01190 (kgd)
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Gene cluster
GFIT
Motif
Pfam:
E1_dh
2-oxoacid_dh
OxoGdeHyase_C
Transket_pyr
2-oxogl_dehyd_N
Motif
Other DBs
NCBI-ProteinID:
AMD86464
UniProt:
A0A109W217
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All DBs
Position
277856..281731
Genome browser
AA seq
1291 aa
AA seq
DB search
MPTHESTAAGAAAFGANEWMVEEMREAWEADPSSVSAQWRELFEKDPTAGLSKDEGGSDA
SSAPAPEPTAVPAPGAVPAGATHPESAPAGEDDTAIRPRRRAATAVQDVTRSDLPPAPTS
DVAPPTSPYAQRVARLAAEGRGASDAADVDSKMKGAPARTAKNMEDSLAIPTATSARAVP
AKVMIENRAIINSHLSHTRGGKVSFTHLIGWAVVEALTEMPGMNVSYTTDEKGKPVLHEP
AHVAFGLAIDVPTSKGERRLMVPSIKQADLLDLAGFVEANQALVRKARDGRLEVADFMGT
TVTLTNPGMIGTLHSVPRLMPGQGAIIGVGSMAYPASFAGASDETLARNGIGKTITLTST
YDHRVIQGALSGEFLRLLETKLLGLDGFWERAFESLRVPHEPVTWARDTTYDAELETGKP
ARVAELIHAFRQRGHLAADTDPLTYRLRRHPDLDITTYGLSLWDLDRTFPTGGLGGTERA
TLRQILDRLREAYCRTVGVEYMHIQDPAQREWWQERLEGTWSPTTDAERRRTLTKLQQAE
AFETFLQTKYIGQKRFSLEGGESLIVLLDRVLDEAAHDGLDEVVIGMAHRGRLNVLTNIA
GKSYAQVFDEFDGNGVIDGAGTGDVKYHLGTEGVFTGTDGVETRVSLAANPSHLETVDGV
VEGIARAKQDRIGLGEKGYTVMPVLVHGDAAFAGQGVVYETLNMSQLPGYRTGGTVHVVV
NNQIGFTTGSASGRSTTYATDLAKGLQVPIFHVNADDPETVARVAKRAYEYRATFHKDVI
IDLICYRRRGHNEGDDPSMTQPVMYRLIDSMPSTRAVYLGQLVGRGEITEEEAQEIETAF
HDELERILTETRAAHSGKDEETSLAEEAAEGQSESDPTLVGRQRSSLELPSSQAAGAGMM
IGWTSAIPKEIVERIGDSQVAYPEGFHIHPKLAKMLEKRQASSREGGIDWGFGELLALGS
LLMEGVPVRFAGEDTRRATFAQRHAVLHDHESGAEWTPLDFLTPDQAPFEIYDSLLSEYA
AMAFEYGYSVERPEALTLWEAQFGDFANGAQSVIDEYVTSAAQKWGQRSGLVLLLPHGQE
GQGPDHSSARIERYLQMCGQDNMRVVMPSTPANHFHVLREQAFRRPRRPLIVFTPKQLLR
LKAATSSVEDFTEGAFQPVIGETEQKVVDGGKVTRVLLCSGRVYYDLIAERAKRGDESVA
IVRLEQLYPLPVEELAEALAPFEGAELVWVQDEPENQGVWPFLALNLPDSITGGKRPGLA
SRHVAAAPAVGTAGAYKRTQAELVAKAFDRG
NT seq
3876 nt
NT seq
+upstream
nt +downstream
nt
gtgccgacgcatgagagcaccgcggctggagccgcagcattcggagccaacgagtggatg
gtggaggagatgcgcgaggcctgggaggccgacccctcctccgtgagcgcccagtggcgc
gagctcttcgagaaggaccccaccgcgggcctgagcaaggacgagggcggcagcgacgcc
tcctccgcccccgcccccgagccgacggctgtccccgcccccggagccgtccccgcgggg
gccacccaccccgagtccgcccccgccggcgaggatgacaccgccatccgcccccgccgt
cgggccgccaccgcggtccaggacgtcacccgctccgacctgccgccggcaccgacctcc
gacgtcgccccgccgacctccccctacgcccagcgcgtcgcccgcctcgccgccgagggc
cgcggcgcctccgacgccgccgacgtcgactccaagatgaagggcgccccggcgcgcacc
gcgaagaacatggaggactcgctcgccatcccgacggcgacctccgcccgcgcggtgccc
gccaaggtcatgatcgagaaccgcgcgatcatcaactcccacctctcgcacacccgcggc
ggcaaggtctccttcacccacctcatcggctgggccgtcgtcgaggccctcaccgagatg
ccgggcatgaacgtctcctacacgacggacgagaagggcaagccggtcctccacgagccg
gcccacgtcgccttcggcctcgccatcgacgtgcccacctcgaagggcgagcgccgcctc
atggtgccctccatcaagcaggcggacctcctcgacctcgccggcttcgtcgaggccaac
caggccctcgtgaggaaggctcgcgacggcaggctcgaggtcgccgacttcatgggcacg
accgtcaccctgaccaaccccggcatgatcggcaccctgcactcggtgccgcgcctcatg
cccggccagggcgccatcatcggggtcggctccatggcctacccggcctccttcgcgggc
gcgagcgacgagacgctcgcccgcaacggcatcggcaagaccatcaccctgacctccacc
tacgaccaccgcgtcatccagggcgccctgtcgggcgagttcctccgcctgctcgagacc
aagctcctcggcctcgacggcttctgggagcgggccttcgagtcgctgcgggtcccgcac
gagcccgtcacgtgggcccgggacaccacctacgacgccgagctcgagaccggcaagccg
gcgcgcgtcgccgagctcatccacgccttccgccagcgcggccacctcgccgcggacacg
gacccgctcacctaccgcctgcgccgtcaccccgacctggacatcacgacctacgggctg
agcctgtgggacctggaccgcaccttcccgaccgggggcctgggcggcaccgagcgcgcg
acgctccgccagatcctcgaccgcctccgcgaggcctactgccgcacggtgggcgtcgag
tacatgcacatccaggacccggcgcagcgcgagtggtggcaggagcgcctcgagggcacc
tggtcccccacgaccgacgccgagcgccgccgcaccctcaccaagctgcagcaggcggag
gccttcgagaccttcctgcagacgaagtacatcggtcagaagcgcttcagcctcgagggc
ggcgagtccctcatcgtcctgctcgaccgcgtcctggacgaggccgcgcacgacggactc
gacgaggtcgtcatcggcatggcccaccgcggccgcctcaacgtgctcaccaacatcgcc
ggcaagtcctacgcgcaggtcttcgacgagttcgacggcaacggcgtcatcgatggcgcc
ggcaccggcgacgtcaagtaccacctgggcacggagggcgtcttcaccggcaccgacggc
gtcgagacccgagtctccctggccgccaacccgtcccacctggagacggtcgacggcgtc
gtcgagggcatcgcccgcgccaagcaggaccgcatcggcctgggcgagaagggctacacg
gtcatgccggtcctcgtccacggcgacgcggccttcgccggccagggcgtcgtctacgag
accctcaacatgtcccagctgcccggctaccggacgggcggcaccgtccacgtcgtcgtc
aacaaccagatcggcttcacgaccggctcggcctcgggccgctcgacgacctacgcgacg
gacctcgccaagggcctccaggtcccgatcttccacgtcaacgcggacgaccccgagacc
gtggcgcgcgtcgcgaagcgcgcctacgagtaccgggcgaccttccacaaggacgtcatc
atcgacctcatctgctaccgccgccgcggtcacaacgagggcgacgacccctcgatgacg
cagccggtcatgtatcgcctcatcgactcgatgccctccacgcgcgccgtctacctcggt
cagctcgtgggccgcggggagatcaccgaggaggaggcccaggagatcgagaccgccttc
cacgacgagctcgagcggatcctcaccgagacgcgcgcggcccactccggcaaggacgag
gagacctccctcgccgaggaggccgcggagggccagtccgagtccgacccgacgctcgtc
gggcgtcagcgctccagcctcgagcttcccagctcgcaggccgccggcgccggcatgatg
atcggctggacgagcgcgatcccgaaggagatcgtcgagcgcatcggcgactcccaggtc
gcctaccccgagggcttccacatccaccccaagctcgcgaagatgctcgagaagcgccag
gcctcctcgcgcgagggcggcatcgactggggcttcggcgagctcctcgccctgggctcc
ctcctcatggagggcgtgccggtccgcttcgcgggcgaggacacccgccgcgccaccttc
gcccagcgccacgcggtcctccacgaccacgagtcgggcgcggagtggacaccgctggac
ttcctcacccctgaccaggcgcccttcgagatctacgactcgctcctgagcgagtacgcg
gcgatggccttcgagtacggctactccgtggagcgcccggaggccctcaccctgtgggag
gcgcagttcggcgacttcgccaacggcgcccagagcgtcatcgacgagtacgtcacctcg
gccgcccagaagtgggggcagcgctccggcctcgtcctcctgctgccgcacggccaggag
ggccagggcccggaccactcctccgcccgcatcgagcgctacctgcagatgtgcggccag
gacaacatgcgcgtcgtcatgccgtcgacgccggcgaaccacttccacgtgctgcgcgag
caggccttccgccgtccgcgccgcccgctcatcgtcttcaccccgaagcagctgctgcgc
ctcaaggcggcgacctcctcggtcgaggacttcaccgagggcgccttccagccggtcatc
ggcgagacggagcagaaggtcgtcgacggcggcaaggtgacccgcgtgctcctgtgctcg
ggccgtgtctactacgacctcatcgccgagcgcgccaagcgcggcgacgagtcggtcgcg
atcgtccgcctcgagcagctctacccgctgcccgtcgaggagctcgccgaggccctcgcc
cccttcgagggcgcggagctcgtgtgggtgcaggacgagccggagaaccagggcgtatgg
cccttcctcgcccttaacctgccggactcgatcacgggcgggaagcggcccggcctggcc
tcgcggcacgtcgcggcggccccggcggtcggcacggcgggcgcctacaagcgcacgcag
gccgagctcgtcgccaaggccttcgaccgcggctga
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