Actinoplanes sp. SE50/110: ACPL_7545
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Entry
ACPL_7545 CDS
T02044
Symbol
sucA
Name
(GenBank) 2-oxoglutarate dehydrogenase E1 component
KO
K01616
multifunctional 2-oxoglutarate metabolism enzyme [EC:
2.2.1.5
4.1.1.71
1.2.4.2
2.3.1.61
]
Organism
ase
Actinoplanes sp. SE50/110
Pathway
ase00020
Citrate cycle (TCA cycle)
ase00630
Glyoxylate and dicarboxylate metabolism
ase00785
Lipoic acid metabolism
ase01100
Metabolic pathways
ase01110
Biosynthesis of secondary metabolites
ase01120
Microbial metabolism in diverse environments
ase01200
Carbon metabolism
ase01210
2-Oxocarboxylic acid metabolism
Module
ase_M00009
Citrate cycle (TCA cycle, Krebs cycle)
ase_M00011
Citrate cycle, second carbon oxidation, 2-oxoglutarate => oxaloacetate
Brite
KEGG Orthology (KO) [BR:
ase00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00020 Citrate cycle (TCA cycle)
ACPL_7545 (sucA)
00630 Glyoxylate and dicarboxylate metabolism
ACPL_7545 (sucA)
09108 Metabolism of cofactors and vitamins
00785 Lipoic acid metabolism
ACPL_7545 (sucA)
Enzymes [BR:
ase01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.4 With a disulfide as acceptor
1.2.4.2 oxoglutarate dehydrogenase (succinyl-transferring)
ACPL_7545 (sucA)
2. Transferases
2.2 Transferring aldehyde or ketonic groups
2.2.1 Transketolases and transaldolases
2.2.1.5 2-hydroxy-3-oxoadipate synthase
ACPL_7545 (sucA)
2.3 Acyltransferases
2.3.1 Transferring groups other than aminoacyl groups
2.3.1.61 dihydrolipoyllysine-residue succinyltransferase
ACPL_7545 (sucA)
4. Lyases
4.1 Carbon-carbon lyases
4.1.1 Carboxy-lyases
4.1.1.71 2-oxoglutarate decarboxylase
ACPL_7545 (sucA)
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SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
E1_dh
OxoGdeHyase_C
2-oxoacid_dh
Transket_pyr
2-oxogl_dehyd_N
Motif
Other DBs
NCBI-ProteinID:
AEV88425
UniProt:
G8S0B7
LinkDB
All DBs
Position
8341460..8345200
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AA seq
1246 aa
AA seq
DB search
MTNTVKEANAAVSTQQTSQDNPLADFGPNEWIVDEMYQRYLADPTSVDPAWHDFFADYKP
ATASGSIVTPDEATAANATKSAAKAGTDAPAAATVAPAKPVTPPAPAAKKAEPVKAAPKP
AAAAQPAPAGAKTTVLRGVAGKIVQNMEASLQVPTATSVRAVPAKLMIDNRIVINNHLSR
GRGGKVSFTHLIGWALVRAVVAHPEMNNIYAEVDGKPTLVQPEHINLGIAIDLAKKDGSR
TLVVPSIKNCEQMDFRQFWQAYEDVVRRARRNELTMDDYAGTTISLTNPGGIGTVHSIPR
LMNGQSAIIGVGALEYPAPYAGMSDETLTDHGVSKVTTLTSTYDHRVIQGAQSGEFLKVM
HELLLGGRDFYDEIFTSLRIPYEPVRWVRDVAHTSEGQIDKAARVIELIHAYRVRGHLMA
DTDPLEFTIRKHPDLDVLQHGLTLWDLDRTFPVGGFAGKQKMKLRDVLGVLRDSYCRRIG
IEYMHIQDPEERRWVQERIEVKYAKPDTDEQKQILLRLNRAEAFETFLQTKYVGQKRFSL
EGGESLIPLLDAVLQSSAEAGLDEMVIGMAHRGRLNVLTNIVGKPYEKLFNEFEGWMDPK
SAHGSGDVKYHLGQTGKYTTPDGRHSTTVSVVANPSHLEAVDPVLEGIVRAKQDRLDLGL
HGYTVLPVLVHGDAAFAGQGVVAETLNLSQLRGYRTGGTVHVVVNNQVGFTTAPEYSRSS
MYSTDVARMVEAPIFHVNGDDPEAVVRVAKLAFEYRQTFNKDVVIDMICYRRRGHNEGDD
PSMTNPRMYQIIDTKRSVRKLYTEELIGRGDITVQDAEEQLRDYQSRLEEVFKATRDAAG
SPPRPHIIAEEPEPQVATAVEADTVRAVGQAHIELPEGFTPHKRVQQLLDRRAKMSTDGG
IDWGFGELIAFGSLLAQGVTVRLAGQDSRRGTFTSRHASIVDSRTGKDFLPIASLATGTA
RFFVHDSLLSEYAAMGFEYGYSVENPDALVLWEAQFGDFVNGAQSIVDEFLSSGEVKWGQ
QSSLVLLLPHGMEGQGPDHSSGRPERFLQLCAQDNMRVANPTTPANYFHLLRRQALSSKR
KPLVVMSPKSLLRHKLAVSSVADFTQGTFQPVLGDAGVNGQPLDAGSVKRVLFCSGKVYY
DLFQARADRGITDTAIIRMEQIYPLPVDELKAVLAQYPNAEDFAWVQEEPANQGAWSFVA
LNLLEHLEGVRLRRISRPAAAAPAVGSAKMHEAEQQALIEASLPRP
NT seq
3741 nt
NT seq
+upstream
nt +downstream
nt
atgacaaacacggtgaaagaggcgaacgcggcagtgtcgacgcagcagacttcgcaggac
aacccactcgcggatttcggtcccaacgagtggatcgtcgacgagatgtatcagcgatac
ctggccgatccgaccagtgtcgaccctgcctggcacgatttcttcgccgactacaagccg
gcgaccgcctcgggctcgatcgtgacacccgacgaggccaccgcggcgaacgcgaccaag
agcgccgccaaggccggcaccgacgcgcccgccgcggccaccgtggcgccggccaagccg
gtcaccccgcccgccccggcggcgaagaaggcggagccggtcaaggccgcaccgaagccc
gcggcggcggcccagcccgccccggccggggcgaagaccacggtcctgcgcggcgtcgcc
ggcaagatcgtgcagaacatggaggcctcgctccaggtccccaccgccacctcggtgcgc
gcggtgccggcgaaactgatgatcgacaaccgcatcgtgatcaacaatcacctctcccgg
ggccggggcggcaaggtcagtttcacgcacctgatcgggtgggcgctggtccgggcggtc
gtcgcgcacccggagatgaacaacatctacgccgaggtcgacggcaagcccacgctggtc
cagccggagcacatcaacctcggcatcgccatcgacctggccaagaaggacgggtcgcgc
accctggtggtgccgtccatcaagaactgcgaacagatggacttccggcagttctggcag
gcgtacgaggacgtggtccgccgcgcccggcgcaacgagctgaccatggacgactacgcc
ggcaccacgatctcgctgaccaacccgggcggcatcggcacggtgcactcgatcccgcgt
ctgatgaacggtcagtccgcgatcatcggcgtcggcgcgctggagtaccccgcgccctac
gccgggatgagcgacgagaccctcaccgaccatggcgtctccaaggtgacgacgctgacc
agcacctacgaccaccgggtcatccagggcgcgcagtccggcgagttcctcaaggtgatg
cacgagctgctgctcggcggccgggacttctacgacgagatcttcacctcgctgcggatc
ccgtacgagccggtccgctgggtgcgcgacgtcgcgcacacctccgagggccagatcgac
aaggccgcccgggtgatcgagctgatccacgcgtaccgggtgcgcggtcacctgatggcc
gacaccgacccgctcgagttcaccatccgcaagcaccccgacctcgacgtgctgcagcac
ggcctcacgctgtgggacctggaccgcacgttcccggtcggcggtttcgccggcaagcag
aagatgaagctgcgcgacgtgctcggcgtgctgcgcgacagctactgccgccggatcggc
atcgagtacatgcacatccaggacccggaggagcgccgctgggttcaggagcgcatcgag
gtcaagtacgccaagccggacaccgacgagcagaagcagatcctgctgcgactcaaccgg
gccgaggcgttcgagaccttcctgcagaccaagtacgtcgggcagaagcggttctcgctg
gagggcggcgagtcgctgatcccgctgctcgacgcggtgctccagtcgtccgccgaggcc
gggctcgacgagatggtgatcggcatggcccaccgcggccggctgaacgtgctcaccaac
atcgtcggcaagccgtacgagaagctcttcaacgagttcgaggggtggatggaccccaag
tcggcgcacggctccggtgacgtgaagtaccacctgggccagaccggcaaatacaccacg
cccgacggccggcactccaccaccgtcagcgtggtcgcgaacccgtcccacctggaggcc
gtcgacccggtcctggagggcatcgtccgggccaagcaggaccgcctcgacctgggcctg
cacggctacacggtgctgccggtgctggtgcacggcgacgccgcgttcgccggtcagggc
gtggtcgccgagacgctgaacctctcccagctgcggggctaccgcaccggtggcaccgtc
cacgtggtcgtgaacaaccaggtcggcttcaccaccgccccggagtacagccgctcgtcg
atgtactcgaccgacgtcgcccggatggtcgaggcgccgatcttccacgtcaacggggac
gacccggaggccgtggtgcgggtcgccaagctggccttcgagtaccgccagacgttcaac
aaggacgtcgtgatcgacatgatctgctaccgccgccgcggtcacaacgagggcgacgac
ccgtcgatgaccaacccgcggatgtaccagatcatcgacaccaagcgcagcgtccgcaag
ctgtacaccgaggagctcatcggccgcggcgacatcaccgtgcaggacgccgaggagcag
ctgcgcgactaccagtcccggctggaggaggtcttcaaggccacccgggacgcggccggc
agcccgccgcggccgcacatcatcgccgaggaaccggagccgcaggtggccaccgcggtc
gaggcggacaccgtgcgggccgtcggccaggcgcacatcgagctgcccgagggcttcacc
ccgcacaagcgggtccagcagctgctcgaccggcgggccaagatgtccaccgacggcggc
atcgactggggcttcggcgagctgatcgcgttcggttcgctgctcgcccagggcgtcacc
gtccggctcgccggtcaggactcccgtcgcggcacgttcacctcgcggcacgcctcgatc
gtcgactcgcgaaccggcaaggacttcctgccgatcgcctcgctggccaccggcaccgcg
cggttcttcgtgcacgactcgctgctctccgagtacgccgcgatgggcttcgagtacggc
tactcggtggagaacccggacgcgctggtcctgtgggaggcccagttcggtgacttcgtc
aacggcgcccagtcgatcgtcgacgagttcctctcctccggcgaggtgaagtggggccag
cagtcgtcgctggtgctgctgctcccgcacggcatggagggccaggggcccgaccactcg
tccggccgcccggagcggttcctgcagctctgcgcacaggacaacatgcgggtggcgaac
ccgaccaccccggcgaactacttccacctgctgcgccgccaggccctgtccagcaagcgc
aagccgctggtcgtcatgtcgccgaagtcgctgctgcggcacaagctcgcggtgtcctcg
gtggccgacttcacccagggcacgttccagccggtgctcggcgacgccggggtcaacggc
cagccgctggacgccggctcggtgaagcgggtgctgttctgctccggcaaggtctactac
gacctgttccaggcccgggccgaccgcggcatcaccgacaccgcgatcatccggatggag
cagatctacccgctgccggtggacgagctcaaggcggtcctggcgcagtacccgaacgcc
gaggacttcgcctgggtccaggaggagccggccaaccagggtgcctggtcgttcgtcgcg
ctcaacctgctggagcacctggagggcgtccggctgcggcggatctcccgcccggcggcg
gccgccccggcggtcggctcggccaagatgcacgaggccgagcagcaggcgctgatcgag
gcgtcgctgccccgcccgtga
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