Amycolatopsis thermalba: L1857_06485
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Entry
L1857_06485 CDS
T08681
Name
(GenBank) NADP-dependent isocitrate dehydrogenase
KO
K00031
isocitrate dehydrogenase [EC:
1.1.1.42
]
Organism
athm
Amycolatopsis thermalba
Pathway
athm00020
Citrate cycle (TCA cycle)
athm00480
Glutathione metabolism
athm01100
Metabolic pathways
athm01110
Biosynthesis of secondary metabolites
athm01120
Microbial metabolism in diverse environments
athm01200
Carbon metabolism
athm01210
2-Oxocarboxylic acid metabolism
athm01230
Biosynthesis of amino acids
Module
athm_M00009
Citrate cycle (TCA cycle, Krebs cycle)
athm_M00010
Citrate cycle, first carbon oxidation, oxaloacetate => 2-oxoglutarate
Brite
KEGG Orthology (KO) [BR:
athm00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00020 Citrate cycle (TCA cycle)
L1857_06485
09106 Metabolism of other amino acids
00480 Glutathione metabolism
L1857_06485
Enzymes [BR:
athm01000
]
1. Oxidoreductases
1.1 Acting on the CH-OH group of donors
1.1.1 With NAD+ or NADP+ as acceptor
1.1.1.42 isocitrate dehydrogenase (NADP+)
L1857_06485
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GFIT
Motif
Pfam:
Iso_dh
Motif
Other DBs
NCBI-ProteinID:
UQS22494
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Position
1318259..1319482
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AA seq
407 aa
AA seq
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MAKIKVEGTVVELDGDEMTRIIWKFIKDKLIHPYLDINLEYYDLGIEERDRTDDQVTIDS
ANAIKKHGVGVKCATITPDEARVEEFGLKKMWRSPNGTIRNILGGVVFREPIIISNIPRL
VPGWTKPIIIGRHAHGDQYKATDFKVPGPGTVTMTYVPEDGSEPIEFEVARYPEGGGVAM
GMYNYRKSIEDFARASLQYGLDRGMPVYMSTKNTILKAYDGMFKDTFQEIFDNEFKADFD
AKGLTYEHRLIDDMVAASLKWEGGYVWACKNYDGDVQSDTVAQGFGSLGLMTSVLRTPDG
KTVEAEAAHGTVTRHYRQHQQGKPTSTNPIASIFAWTRGLEHRGKLDGNSELVGFANKLE
QVVIETVESGKMTKDLALLVGKDQPFQTTEEFLATLDENLAAKIAQG
NT seq
1224 nt
NT seq
+upstream
nt +downstream
nt
atggccaagatcaaggtcgagggcaccgtcgtagaactcgacggcgacgagatgactcgc
atcatctggaagttcatcaaggacaagctgatccacccgtatctcgacatcaacctcgag
tactacgacctcggcatcgaggagcgggaccggactgacgaccaggtcacgatcgattcc
gcgaacgccatcaagaagcacggcgtcggcgtcaagtgcgccaccatcaccccggacgag
gcccgggtcgaggagttcggcctgaagaagatgtggcggagccccaacggcaccatccgc
aacatcctcggcggcgtcgtcttccgtgagccgatcatcatctccaacatcccgcggctg
gtcccgggctggacgaagccgatcatcatcggccgtcacgcgcacggtgaccagtacaag
gccaccgacttcaaggtccccggccccggcacggtgaccatgacgtacgtgcccgaggac
ggctccgagccgatcgagttcgaggtcgcccgctacccggagggtggcggcgtcgcgatg
ggcatgtacaactaccgcaagtcgatcgaggacttcgcgcgcgcctcgctgcagtacggc
ctggaccgcggcatgccggtctacatgtcgacgaagaacaccatcctgaaggcctacgac
ggcatgttcaaggacaccttccaggagatcttcgacaacgagttcaaggccgacttcgac
gccaagggcctgacctacgagcaccgcctgatcgacgacatggtcgccgcctcgctgaag
tgggagggcggctacgtctgggcgtgcaagaactacgacggtgacgtgcagtccgacacc
gtggcgcagggcttcggctcgctgggcctgatgacctcggtgctgcgcacgccggacggc
aagaccgtggaagccgaggccgcgcacggcacggtcacccggcactaccgccagcaccag
cagggcaagccgacctcgacgaacccgatcgcgtcgatcttcgcgtggacccggggtctc
gagcaccgcggcaagctggacggcaactccgagctggtgggcttcgccaacaagctcgag
caggtcgtcatcgagaccgtcgagagcggcaagatgaccaaggacctggcgctgctcgtc
ggcaaggaccagccgttccagacgacggaggagttcctggcgaccctggacgagaacctg
gcggcgaagatcgcccagggctga
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