Bifidobacterium breve DSM 20213 = JCM 1192: BBBR_0278
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Entry
BBBR_0278 CDS
T04525
Name
(GenBank) D-alanine-D-alanine ligase
KO
K01921
D-alanine-D-alanine ligase [EC:
6.3.2.4
]
Organism
bbrd
Bifidobacterium breve DSM 20213 = JCM 1192
Pathway
bbrd00470
D-Amino acid metabolism
bbrd00550
Peptidoglycan biosynthesis
bbrd01100
Metabolic pathways
bbrd01502
Vancomycin resistance
Brite
KEGG Orthology (KO) [BR:
bbrd00001
]
09100 Metabolism
09106 Metabolism of other amino acids
00470 D-Amino acid metabolism
BBBR_0278
09107 Glycan biosynthesis and metabolism
00550 Peptidoglycan biosynthesis
BBBR_0278
09160 Human Diseases
09175 Drug resistance: antimicrobial
01502 Vancomycin resistance
BBBR_0278
09180 Brite Hierarchies
09181 Protein families: metabolism
01011 Peptidoglycan biosynthesis and degradation proteins [BR:
bbrd01011
]
BBBR_0278
Enzymes [BR:
bbrd01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.4 D-alanine---D-alanine ligase
BBBR_0278
Peptidoglycan biosynthesis and degradation proteins [BR:
bbrd01011
]
Precursor biosynthesis
Amino acid ligase
BBBR_0278
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Gene cluster
GFIT
Motif
Pfam:
Dala_Dala_lig_C
Dala_Dala_lig_N
ATP-grasp
ATP-grasp_4
CPSase_L_D2
GARS_A
Motif
Other DBs
NCBI-ProteinID:
BAQ99316
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Position
357855..359042
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AA seq
395 aa
AA seq
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MAKKRIVVLYGGRADEHSISCISTAGVLAAMDTERFEPIPVGITKDGKWIIDGEDPRGWN
LDGDELPTVKITPKSRPVILDPSRGKDGFFAGEPDHLSNADSGFGTSFVNLSDPEIHHVL
TSLGHVDAVLPVLHGPYGEDGTVQGLLEMMGVPYVGCGVFASAACMDKHYTKVVLNAAGI
PTAPGIMVDARAFTAADVVAQIEVAGLAYPLFVKPSRAGSSFGVTKVDKAEDLETQQDRV
AAAIATAGEHDWKVLIEQGIDGREIECAVLCPKAGDEPEASWPGEIVLDHQNDDQFYDFD
SKYMDASASHVEVPANLPVSVLEDVRDVARRAFKAVDGAGLSRVDTFVTPDGTVMVNEIN
TMPGFTPISMYPKAWDATGVGYTELITRLIEGVLK
NT seq
1188 nt
NT seq
+upstream
nt +downstream
nt
atggccaagaaacgtattgtggtgctctatggtgggcgtgcggatgaacattcgatttcc
tgcatctccacggccggcgtgctggcggctatggataccgaacgtttcgagccgattccg
gtgggcatcaccaaggacggcaagtggattatcgacggtgaggatccgcgcggctggaat
ctggacggcgacgagctgccgaccgtgaagatcacgccgaaatcccgtccggtgattctc
gacccctcgcgaggcaaggacggtttctttgccggtgagccggatcatctcagcaatgcc
gactccggttttggcaccagctttgtgaacttgtccgatcctgagatacatcacgtgctg
acctcgctggggcatgtcgatgcggtgctgcctgtgctgcatggcccttacggcgaggac
ggcacggtgcagggtcttcttgagatgatgggtgtgccgtatgtgggctgtggcgtgttc
gcctctgccgcctgcatggataagcactacaccaaagtggtgctcaatgctgccggtatt
ccgacggctcccggcattatggtggatgcgcgcgcgttcaccgcagccgatgtggtcgcc
cagatcgaggtcgccggattggcttatccgctgttcgtcaagccttcccgtgctggatcc
agctttggcgtcaccaaggtggataaagccgaggatctggaaacccagcaggaccgtgtg
gccgctgccatcgccacggccggtgagcatgactggaaggtgctcatcgagcagggcatc
gacggccgcgagatcgaatgcgccgtgctgtgcccgaaggcgggcgatgagcccgaggcc
agctggcccggcgaaatcgtgcttgaccaccagaatgacgaccagttctatgatttcgat
tccaagtacatggatgcttccgccagccatgtggaagtgccggccaacctgcccgtcagc
gtgcttgaggatgtacgcgacgtggctcgccgtgcgttcaaggccgtagatggagcgggt
ctgagccgcgtggataccttcgtgactccggacggcaccgtgatggtcaacgagatcaac
accatgcctggcttcacgccgatttccatgtatcccaaggcatgggacgccacgggtgtg
ggatacaccgaactcatcacccgtctgatcgaaggcgtgttgaagtaa
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